Causes of Death in Hospitalized HIV Patients in the Early Anti-Retroviral Therapy Era.
Identifieur interne : 000135 ( PubMed/Corpus ); précédent : 000134; suivant : 000136Causes of Death in Hospitalized HIV Patients in the Early Anti-Retroviral Therapy Era.
Auteurs : M. Lartey ; A. Asante-Quashie ; A. Essel ; E. Kenu ; V. Ganu ; A. NeequayeSource :
- Ghana medical journal [ 0016-9560 ] ; 2015.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Aged, 80 and over, Antiretroviral Therapy, Highly Active (mortality), Cause of Death, Female, Ghana (epidemiology), HIV Infections (drug therapy), HIV Infections (mortality), Hospital Mortality, Hospitalization (statistics & numerical data), Humans, Male, Middle Aged, Retrospective Studies, Tuberculosis, Pulmonary (mortality), Young Adult.
- MESH :
- geographic , epidemiology : Ghana.
- drug therapy : HIV Infections.
- mortality : Antiretroviral Therapy, Highly Active, HIV Infections, Tuberculosis, Pulmonary.
- statistics & numerical data : Hospitalization.
- Adolescent, Adult, Aged, Aged, 80 and over, Cause of Death, Female, Hospital Mortality, Humans, Male, Middle Aged, Retrospective Studies, Young Adult.
Abstract
To establish the cause(s) of death among persons with HIV and AIDS admitted to the Fevers Unit of the Korle-Bu Teaching Hospital (KBTH) in 2007 and to determine whether they were AIDS-related in the era of availability of HAART.
PubMed: 26339078
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Essel</name><affiliation><nlm:affiliation>Department of Community Health, University of Ghana Medical School, Korle Bu.</nlm:affiliation></affiliation></author><author><name sortKey="Kenu, E" sort="Kenu, E" uniqKey="Kenu E" first="E" last="Kenu">E. Kenu</name><affiliation><nlm:affiliation>Department of Medicine, Korle-Bu Teaching Hospital, Korle-Bu, Accra, Ghana.</nlm:affiliation></affiliation></author><author><name sortKey="Ganu, V" sort="Ganu, V" uniqKey="Ganu V" first="V" last="Ganu">V. Ganu</name><affiliation><nlm:affiliation>Department of Medicine, Korle-Bu Teaching Hospital, Korle-Bu, Accra, Ghana.</nlm:affiliation></affiliation></author><author><name sortKey="Neequaye, A" sort="Neequaye, A" uniqKey="Neequaye A" first="A" last="Neequaye">A. Neequaye</name><affiliation><nlm:affiliation>Department of Medicine, University of Ghana Medical School, College of Health Sciences, Korle Bu, Accra, Ghana ; Department of Medicine, Korle-Bu Teaching Hospital, Korle-Bu, Accra, Ghana.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:26339078</idno><idno type="pmid">26339078</idno><idno type="wicri:Area/PubMed/Corpus">000135</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000135</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Causes of Death in Hospitalized HIV Patients in the Early Anti-Retroviral Therapy Era.</title><author><name sortKey="Lartey, M" sort="Lartey, M" uniqKey="Lartey M" first="M" last="Lartey">M. Lartey</name><affiliation><nlm:affiliation>Department of Medicine, University of Ghana Medical School, College of Health Sciences, Korle Bu, Accra, Ghana ; Department of Medicine, Korle-Bu Teaching Hospital, Korle-Bu, Accra, Ghana.</nlm:affiliation></affiliation></author><author><name sortKey="Asante Quashie, A" sort="Asante Quashie, A" uniqKey="Asante Quashie A" first="A" last="Asante-Quashie">A. Asante-Quashie</name><affiliation><nlm:affiliation>International Organization for Migration, Accra, Ghana.</nlm:affiliation></affiliation></author><author><name sortKey="Essel, A" sort="Essel, A" uniqKey="Essel A" first="A" last="Essel">A. Essel</name><affiliation><nlm:affiliation>Department of Community Health, University of Ghana Medical School, Korle Bu.</nlm:affiliation></affiliation></author><author><name sortKey="Kenu, E" sort="Kenu, E" uniqKey="Kenu E" first="E" last="Kenu">E. Kenu</name><affiliation><nlm:affiliation>Department of Medicine, Korle-Bu Teaching Hospital, Korle-Bu, Accra, Ghana.</nlm:affiliation></affiliation></author><author><name sortKey="Ganu, V" sort="Ganu, V" uniqKey="Ganu V" first="V" last="Ganu">V. Ganu</name><affiliation><nlm:affiliation>Department of Medicine, Korle-Bu Teaching Hospital, Korle-Bu, Accra, Ghana.</nlm:affiliation></affiliation></author><author><name sortKey="Neequaye, A" sort="Neequaye, A" uniqKey="Neequaye A" first="A" last="Neequaye">A. Neequaye</name><affiliation><nlm:affiliation>Department of Medicine, University of Ghana Medical School, College of Health Sciences, Korle Bu, Accra, Ghana ; Department of Medicine, Korle-Bu Teaching Hospital, Korle-Bu, Accra, Ghana.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Ghana medical journal</title><idno type="ISSN">0016-9560</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Antiretroviral Therapy, Highly Active (mortality)</term><term>Cause of Death</term><term>Female</term><term>Ghana (epidemiology)</term><term>HIV Infections (drug therapy)</term><term>HIV Infections (mortality)</term><term>Hospital Mortality</term><term>Hospitalization (statistics & numerical data)</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Retrospective Studies</term><term>Tuberculosis, Pulmonary (mortality)</term><term>Young Adult</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Ghana</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Antiretroviral Therapy, Highly Active</term><term>HIV Infections</term><term>Tuberculosis, Pulmonary</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Hospitalization</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Cause of Death</term><term>Female</term><term>Hospital Mortality</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Retrospective Studies</term><term>Young Adult</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To establish the cause(s) of death among persons with HIV and AIDS admitted to the Fevers Unit of the Korle-Bu Teaching Hospital (KBTH) in 2007 and to determine whether they were AIDS-related in the era of availability of HAART.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26339078</PMID><DateCreated><Year>2015</Year><Month>09</Month><Day>04</Day></DateCreated><DateCompleted><Year>2016</Year><Month>06</Month><Day>03</Day></DateCompleted><DateRevised><Year>2015</Year><Month>09</Month><Day>07</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0016-9560</ISSN><JournalIssue CitedMedium="Internet"><Volume>49</Volume><Issue>1</Issue><PubDate><Year>2015</Year><Month>Mar</Month></PubDate></JournalIssue><Title>Ghana medical journal</Title><ISOAbbreviation>Ghana Med J</ISOAbbreviation></Journal><ArticleTitle>Causes of Death in Hospitalized HIV Patients in the Early Anti-Retroviral Therapy Era.</ArticleTitle><Pagination><MedlinePgn>7-11</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To establish the cause(s) of death among persons with HIV and AIDS admitted to the Fevers Unit of the Korle-Bu Teaching Hospital (KBTH) in 2007 and to determine whether they were AIDS-related in the era of availability of HAART.</AbstractText><AbstractText Label="METHOD" NlmCategory="METHODS">Retrospective chart review of all deaths that occurred in the year 2007 among inpatients with HIV infection. Cause of Death (COD) was established with post mortem diagnosis, where not available ICD-10 was reviewed independently by two physicians experienced in HIV medicine and a consensus reached as to the most likely COD.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">In the year under review, 215 (97%) of the 221 adult deaths studied were caused by AIDS and HIV-associated illnesses. Of these, 123 (55.7%) were due to an AIDS-defining illness as described in CDC Category 3 or WHO stage 4. Infections accounted for most of the deaths 158 (71.5%), many of them opportunistic 82 (51.8%). Tuberculosis was the commonest COD. Clinical diagnosis of TB was accurate in 54% of deaths, but was not validated by autopsy in 36% of deaths. There were few deaths (14.5%) in patients on HAART.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">In a developing country like Ghana where HAART was still not fully accessible, AIDS-related events remained the major causes of death in persons living with HIV. Total scale-up of the ART programme with continuous availability of antiretrovirals is therefore imperative to reduce deaths from AIDS and HIV associated illnesses. There is need for interventions for early diagnosis as well as reduction in late presentation and also better diagnostic tools for tuberculosis.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Lartey</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Ghana Medical School, College of Health Sciences, Korle Bu, Accra, Ghana ; Department of Medicine, Korle-Bu Teaching Hospital, Korle-Bu, Accra, Ghana.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Asante-Quashie</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>International Organization for Migration, Accra, Ghana.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Essel</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Community Health, University of Ghana Medical School, Korle Bu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kenu</LastName><ForeName>E</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Medicine, Korle-Bu Teaching Hospital, Korle-Bu, Accra, Ghana.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ganu</LastName><ForeName>V</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Department of Medicine, Korle-Bu Teaching Hospital, Korle-Bu, Accra, Ghana.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Neequaye</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Ghana Medical School, College of Health Sciences, Korle Bu, Accra, Ghana ; Department of Medicine, Korle-Bu Teaching Hospital, Korle-Bu, Accra, Ghana.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Ghana</Country><MedlineTA>Ghana Med J</MedlineTA><NlmUniqueID>0073210</NlmUniqueID><ISSNLinking>0016-9560</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>J Korean Med Sci. 2013 Jan;28(1):67-73</RefSource><PMID Version="1">23341714</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>HIV Med. 2002 Jul;3(3):195-9</RefSource><PMID Version="1">12139658</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Infect Dev Ctries. 2011 May;5(5):377-82</RefSource><PMID Version="1">21628815</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>HIV Med. 2008 Aug;9(7):535-43</RefSource><PMID Version="1">18554309</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>MMWR Recomm Rep. 2008 Dec 5;57(RR-10):1-12</RefSource><PMID 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RefType="Cites"><RefSource>Ann Intern Med. 2006 Sep 19;145(6):397-406</RefSource><PMID Version="1">16983127</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Curr HIV Res. 2008 Jan;6(1):77-81</RefSource><PMID Version="1">18288979</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>HIV Med. 2013 Nov;14(10):596-604</RefSource><PMID Version="1">23672663</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>AIDS Care. 2012;24(4):478-90</RefSource><PMID Version="1">22148973</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D023241" MajorTopicYN="N">Antiretroviral Therapy, Highly Active</DescriptorName><QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002423" MajorTopicYN="N">Cause of Death</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005869" MajorTopicYN="N" Type="Geographic">Ghana</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015658" MajorTopicYN="N">HIV Infections</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017052" MajorTopicYN="Y">Hospital Mortality</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006760" MajorTopicYN="N">Hospitalization</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014397" MajorTopicYN="N">Tuberculosis, Pulmonary</DescriptorName><QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList><OtherID Source="NLM">PMC4549815</OtherID><KeywordList 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