Improvement of clinical algorithms for the diagnosis of Neisseria gonorrhoeae and Chlamydia trachomatis by the use of Gram-stained smears among female sex workers in Accra, Ghana.
Identifieur interne : 000748 ( PubMed/Checkpoint ); précédent : 000747; suivant : 000749Improvement of clinical algorithms for the diagnosis of Neisseria gonorrhoeae and Chlamydia trachomatis by the use of Gram-stained smears among female sex workers in Accra, Ghana.
Auteurs : G. Deceuninck [Canada] ; C. Asamoah-Adu ; N. Khonde ; J. Pépin ; E H Frost ; S. Deslandes ; A. Asamoah-Adu ; V. Bekoe ; M. AlarySource :
- Sexually transmitted diseases [ 0148-5717 ] ; 2000.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Algorithmes, Cervicite (diagnostic), Cervicite (microbiologie), Chlamydia trachomatis (isolement et purification), Chlorure de méthylrosanilinium, Femelle, Frottis vaginal (), Ghana, Gonorrhée (diagnostic), Gonorrhée (microbiologie), Humains, Infections à Chlamydia (diagnostic), Infections à Chlamydia (microbiologie), Neisseria gonorrhoeae (isolement et purification), Phénazines, Prostitution, Sensibilité et spécificité, Études transversales.
- MESH :
- diagnostic : Cervicite, Gonorrhée, Infections à Chlamydia.
- isolement et purification : Chlamydia trachomatis, Neisseria gonorrhoeae.
- microbiologie : Cervicite, Gonorrhée, Infections à Chlamydia.
- Adulte, Adulte d'âge moyen, Algorithmes, Chlorure de méthylrosanilinium, Femelle, Frottis vaginal, Ghana, Humains, Phénazines, Prostitution, Sensibilité et spécificité, Études transversales.
English descriptors
- KwdEn :
- Adult, Algorithms, Chlamydia Infections (diagnosis), Chlamydia Infections (microbiology), Chlamydia trachomatis (isolation & purification), Cross-Sectional Studies, Female, Gentian Violet, Ghana, Gonorrhea (diagnosis), Gonorrhea (microbiology), Humans, Middle Aged, Neisseria gonorrhoeae (isolation & purification), Phenazines, Sensitivity and Specificity, Sex Work, Uterine Cervicitis (diagnosis), Uterine Cervicitis (microbiology), Vaginal Smears (methods).
- MESH :
- chemical : Gentian Violet, Phenazines.
- diagnosis : Chlamydia Infections, Gonorrhea, Uterine Cervicitis.
- isolation & purification : Chlamydia trachomatis, Neisseria gonorrhoeae.
- methods : Vaginal Smears.
- microbiology : Chlamydia Infections, Gonorrhea, Uterine Cervicitis.
- Adult, Algorithms, Cross-Sectional Studies, Female, Ghana, Humans, Middle Aged, Sensitivity and Specificity, Sex Work.
Abstract
Screening for cervical infection is difficult in developing countries. Screening strategies must be improved for high-risk women, such as female sex workers.
PubMed: 10949431
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:10949431Le document en format XML
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<term>Algorithms</term>
<term>Chlamydia Infections (diagnosis)</term>
<term>Chlamydia Infections (microbiology)</term>
<term>Chlamydia trachomatis (isolation & purification)</term>
<term>Cross-Sectional Studies</term>
<term>Female</term>
<term>Gentian Violet</term>
<term>Ghana</term>
<term>Gonorrhea (diagnosis)</term>
<term>Gonorrhea (microbiology)</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Neisseria gonorrhoeae (isolation & purification)</term>
<term>Phenazines</term>
<term>Sensitivity and Specificity</term>
<term>Sex Work</term>
<term>Uterine Cervicitis (diagnosis)</term>
<term>Uterine Cervicitis (microbiology)</term>
<term>Vaginal Smears (methods)</term>
</keywords>
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<term>Adulte d'âge moyen</term>
<term>Algorithmes</term>
<term>Cervicite (diagnostic)</term>
<term>Cervicite (microbiologie)</term>
<term>Chlamydia trachomatis (isolement et purification)</term>
<term>Chlorure de méthylrosanilinium</term>
<term>Femelle</term>
<term>Frottis vaginal ()</term>
<term>Ghana</term>
<term>Gonorrhée (diagnostic)</term>
<term>Gonorrhée (microbiologie)</term>
<term>Humains</term>
<term>Infections à Chlamydia (diagnostic)</term>
<term>Infections à Chlamydia (microbiologie)</term>
<term>Neisseria gonorrhoeae (isolement et purification)</term>
<term>Phénazines</term>
<term>Prostitution</term>
<term>Sensibilité et spécificité</term>
<term>Études transversales</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Gentian Violet</term>
<term>Phenazines</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Chlamydia Infections</term>
<term>Gonorrhea</term>
<term>Uterine Cervicitis</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Cervicite</term>
<term>Gonorrhée</term>
<term>Infections à Chlamydia</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Chlamydia trachomatis</term>
<term>Neisseria gonorrhoeae</term>
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<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Chlamydia trachomatis</term>
<term>Neisseria gonorrhoeae</term>
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<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Vaginal Smears</term>
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<keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Cervicite</term>
<term>Gonorrhée</term>
<term>Infections à Chlamydia</term>
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<keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Chlamydia Infections</term>
<term>Gonorrhea</term>
<term>Uterine Cervicitis</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Algorithms</term>
<term>Cross-Sectional Studies</term>
<term>Female</term>
<term>Ghana</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Sensitivity and Specificity</term>
<term>Sex Work</term>
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<term>Adulte d'âge moyen</term>
<term>Algorithmes</term>
<term>Chlorure de méthylrosanilinium</term>
<term>Femelle</term>
<term>Frottis vaginal</term>
<term>Ghana</term>
<term>Humains</term>
<term>Phénazines</term>
<term>Prostitution</term>
<term>Sensibilité et spécificité</term>
<term>Études transversales</term>
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<front><div type="abstract" xml:lang="en">Screening for cervical infection is difficult in developing countries. Screening strategies must be improved for high-risk women, such as female sex workers.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">10949431</PMID>
<DateCreated><Year>2000</Year>
<Month>11</Month>
<Day>21</Day>
</DateCreated>
<DateCompleted><Year>2001</Year>
<Month>01</Month>
<Day>04</Day>
</DateCompleted>
<DateRevised><Year>2016</Year>
<Month>11</Month>
<Day>24</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0148-5717</ISSN>
<JournalIssue CitedMedium="Print"><Volume>27</Volume>
<Issue>7</Issue>
<PubDate><Year>2000</Year>
<Month>Aug</Month>
</PubDate>
</JournalIssue>
<Title>Sexually transmitted diseases</Title>
<ISOAbbreviation>Sex Transm Dis</ISOAbbreviation>
</Journal>
<ArticleTitle>Improvement of clinical algorithms for the diagnosis of Neisseria gonorrhoeae and Chlamydia trachomatis by the use of Gram-stained smears among female sex workers in Accra, Ghana.</ArticleTitle>
<Pagination><MedlinePgn>401-10</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Screening for cervical infection is difficult in developing countries. Screening strategies must be improved for high-risk women, such as female sex workers.</AbstractText>
<AbstractText Label="GOAL" NlmCategory="OBJECTIVE">To evaluate the sensitivity and specificity of screening algorithms for cervical infection pathogens among female sex workers in Accra, Ghana.</AbstractText>
<AbstractText Label="STUDY DESIGN" NlmCategory="METHODS">A cross-sectional study among female sex workers was conducted. Each woman underwent an interview and a clinical examination. Biologic samples were obtained for the diagnosis of HIV, syphilis, bacterial vaginosis, yeast infection, Trichomonas vaginalis, Neisseria gonorrhoeae, and Chlamydia trachomatis infection. Signs and symptoms associated with cervicitis agents were identified. Algorithms for the diagnosis of cervical infection were tested by computer simulations.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The following prevalences were observed: HIV, 76.6%; N. gonorrhoeae, 33.7%; C. trachomatis, 10.1%; candidiasis, 24.4%; T. vaginalis, 31.4%; bacterial vaginosis, 2.3%; serologic syphilis, 4.6%; and genital ulcers on clinical examination, 10.6%. The best performance of algorithms were reached when using a combination of clinical signs and a search for gram-negative diplococci on cervical smears (sensitivity, 64.4%; specificity, 80.0%).</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">In the algorithms, examination of Gram-stained genital smears in female sex workers without clinical signs of cervicitis improved sensitivity without altering specificity for the diagnosis of cervical infection.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Deceuninck</LastName>
<ForeName>G</ForeName>
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<AffiliationInfo><Affiliation>Epidemiology Research Group, Centre Hospitalier Affilé Universitaire de Québec, Canada.</Affiliation>
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<ForeName>A</ForeName>
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<Author ValidYN="Y"><LastName>Bekoe</LastName>
<ForeName>V</ForeName>
<Initials>V</Initials>
</Author>
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<ForeName>M</ForeName>
<Initials>M</Initials>
</Author>
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<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D023362">Evaluation Studies</PublicationType>
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<MedlineTA>Sex Transm Dis</MedlineTA>
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<ISSNLinking>0148-5717</ISSNLinking>
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<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C035863">Gram's stain</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D010619">Phenazines</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>J4Z741D6O5</RegistryNumber>
<NameOfSubstance UI="D005840">Gentian Violet</NameOfSubstance>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000465" MajorTopicYN="N">Algorithms</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002690" MajorTopicYN="N">Chlamydia Infections</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002692" MajorTopicYN="N">Chlamydia trachomatis</DescriptorName>
<QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003430" MajorTopicYN="N">Cross-Sectional Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005840" MajorTopicYN="Y">Gentian Violet</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005869" MajorTopicYN="N">Ghana</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006069" MajorTopicYN="N">Gonorrhea</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009344" MajorTopicYN="N">Neisseria gonorrhoeae</DescriptorName>
<QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010619" MajorTopicYN="Y">Phenazines</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012680" MajorTopicYN="N">Sensitivity and Specificity</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011477" MajorTopicYN="N">Sex Work</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002575" MajorTopicYN="N">Uterine Cervicitis</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014626" MajorTopicYN="N">Vaginal Smears</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName>
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</MeshHeadingList>
<OtherID Source="PIP">151113</OtherID>
<OtherID Source="POP">00295872</OtherID>
<KeywordList Owner="PIP"><Keyword MajorTopicYN="N">Africa</Keyword>
<Keyword MajorTopicYN="N">Africa South Of The Sahara</Keyword>
<Keyword MajorTopicYN="N">Behavior</Keyword>
<Keyword MajorTopicYN="Y">Chlamydia--women</Keyword>
<Keyword MajorTopicYN="Y">Cross Sectional Analysis</Keyword>
<Keyword MajorTopicYN="N">Developing Countries</Keyword>
<Keyword MajorTopicYN="N">Diseases</Keyword>
<Keyword MajorTopicYN="N">English Speaking Africa</Keyword>
<Keyword MajorTopicYN="N">Examinations And Diagnoses</Keyword>
<Keyword MajorTopicYN="N">Ghana</Keyword>
<Keyword MajorTopicYN="Y">Gonorrhea--women</Keyword>
<Keyword MajorTopicYN="N">Infections</Keyword>
<Keyword MajorTopicYN="Y">Laboratory Examinations And Diagnoses</Keyword>
<Keyword MajorTopicYN="Y">Prostitutes--women</Keyword>
<Keyword MajorTopicYN="N">Reproductive Tract Infections</Keyword>
<Keyword MajorTopicYN="N">Research Methodology</Keyword>
<Keyword MajorTopicYN="Y">Research Report</Keyword>
<Keyword MajorTopicYN="N">Sex Behavior</Keyword>
<Keyword MajorTopicYN="N">Sexually Transmitted Diseases</Keyword>
<Keyword MajorTopicYN="N">Western Africa</Keyword>
<Keyword MajorTopicYN="Y">Women</Keyword>
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<GeneralNote Owner="PIP">TJ: SEXUALLY TRANSMITTED DISEASES.</GeneralNote>
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