Le SIDA au Ghana (serveur d'exploration)

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Screening for viral markers in volunteer and replacement blood donors in West Africa.

Identifieur interne : 000725 ( PubMed/Checkpoint ); précédent : 000724; suivant : 000726

Screening for viral markers in volunteer and replacement blood donors in West Africa.

Auteurs : F. Sarkodie [Ghana] ; M. Adarkwa ; Y. Adu-Sarkodie ; D. Candotti ; J W Acheampong ; J P Allain

Source :

RBID : pubmed:11840974

Descripteurs français

English descriptors

Abstract

West Africa is a highly endemic area for viral infections. The prevalence of five viral markers was determined in Ghanaian blood donors.

PubMed: 11840974


Affiliations:


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pubmed:11840974

Le document en format XML

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<term>Blood Donors</term>
<term>Blood Transfusion (adverse effects)</term>
<term>Enzyme-Linked Immunosorbent Assay</term>
<term>Family</term>
<term>Female</term>
<term>Ghana (epidemiology)</term>
<term>HIV Antibodies (blood)</term>
<term>HIV Core Protein p24 (blood)</term>
<term>HIV Seroprevalence</term>
<term>HTLV-I Antibodies (blood)</term>
<term>HTLV-II Antibodies (blood)</term>
<term>Hepatitis B Surface Antigens (blood)</term>
<term>Hepatitis C Antibodies (blood)</term>
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<term>Male</term>
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<term>RNA, Viral (blood)</term>
<term>Seroepidemiologic Studies</term>
<term>Viremia (blood)</term>
<term>Viremia (diagnosis)</term>
<term>Viremia (epidemiology)</term>
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<term>Volunteers</term>
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<term>Ghana (épidémiologie)</term>
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<term>Mâle</term>
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<term>Séroprévalence du VIH</term>
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<term>Transfusion sanguine (effets indésirables)</term>
<term>Virémie ()</term>
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<term>HIV Antibodies</term>
<term>HIV Core Protein p24</term>
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<term>Donneurs de sang</term>
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<front>
<div type="abstract" xml:lang="en">West Africa is a highly endemic area for viral infections. The prevalence of five viral markers was determined in Ghanaian blood donors.</div>
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<Year>2001</Year>
<Month>07</Month>
<Day>13</Day>
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<Year>2001</Year>
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<Title>Vox sanguinis</Title>
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<ArticleTitle>Screening for viral markers in volunteer and replacement blood donors in West Africa.</ArticleTitle>
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<AbstractText Label="BACKGROUND AND OBJECTIVES" NlmCategory="OBJECTIVE">West Africa is a highly endemic area for viral infections. The prevalence of five viral markers was determined in Ghanaian blood donors.</AbstractText>
<AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">Replacement and volunteer blood donors were screened using enzyme immunoassays (EIAs) for hepatitis B surface antigen (HBsAg), human immunodeficiency virus antibodies (anti-HIV), HIV p24 antigen, human T-cell lymphocytotrophic virus-I and -II antibodies (anti-HTLV-I/II) and hepatitis C virus antibodies (anti-HCV).</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">HBsAg was present at an equally high frequency (15%) in young volunteer (median age 18 years) and older replacement (median age 33 years) blood donors. In contrast, the prevalence of anti-HIV and anti-HCV was significantly higher in replacement blood donors (2.4 and 0.3%, respectively, P < 0.001). HCV RNA was detected in 74 or 55% of seropositive donors, depending on the confirmatory criteria used. No p24 antigen-positive/anti-HIV-negative donations were found. The prevalence of HTLV-I/II was generally low (0.5%).</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">All blood donations should be screened for hepatitis B virus (HBV), HIV and HCV markers.</AbstractText>
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