Diagnosis of dual human immunodeficiency virus types 1 and 2 infections in a resource-limited setting.
Identifieur interne : 000560 ( PubMed/Checkpoint ); précédent : 000559; suivant : 000561Diagnosis of dual human immunodeficiency virus types 1 and 2 infections in a resource-limited setting.
Auteurs : K W C. Sagoe [Ghana] ; A A Agyei ; M. Lartey ; T K Adiku ; J A A. Mingle ; M. ArensSource :
- East African medical journal [ 0012-835X ] ; 2009.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Femelle, Ghana, Humains, Jeune adulte, Mâle, Pays en voie de développement, Sujet âgé, Séropositivité VIH (diagnostic), VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (immunologie), VIH-2 (Virus de l'Immunodéficience Humaine de type 2) (immunologie), Études transversales.
- MESH :
- diagnostic : Séropositivité VIH.
- immunologie : VIH-1 (Virus de l'Immunodéficience Humaine de type 1), VIH-2 (Virus de l'Immunodéficience Humaine de type 2).
- Adolescent, Adulte, Adulte d'âge moyen, Femelle, Ghana, Humains, Jeune adulte, Mâle, Pays en voie de développement, Sujet âgé, Études transversales.
- Wicri :
- geographic : Ghana.
English descriptors
- KwdEn :
- MESH :
- geographic : Ghana.
- diagnosis : HIV Seropositivity.
- immunology : HIV-1, HIV-2.
- Adolescent, Adult, Aged, Cross-Sectional Studies, Developing Countries, Female, Humans, Male, Middle Aged, Young Adult.
Abstract
The presence of dual HIV-1/HIV-2 infection in Ghana and the different drug requirements for the treatment of HIV-1 and HIV-2 presents difficulties for the treatment of dual infections with both viruses.
PubMed: 21644411
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Box 4236, Accra</wicri:regionArea><placeName><settlement type="city">Accra</settlement><region nuts="2">Région du Grand Accra</region></placeName></affiliation></author><author><name sortKey="Agyei, A A" sort="Agyei, A A" uniqKey="Agyei A" first="A A" last="Agyei">A A Agyei</name></author><author><name sortKey="Lartey, M" sort="Lartey, M" uniqKey="Lartey M" first="M" last="Lartey">M. Lartey</name></author><author><name sortKey="Adiku, T K" sort="Adiku, T K" uniqKey="Adiku T" first="T K" last="Adiku">T K Adiku</name></author><author><name sortKey="Mingle, J A A" sort="Mingle, J A A" uniqKey="Mingle J" first="J A A" last="Mingle">J A A. Mingle</name></author><author><name sortKey="Arens, M" sort="Arens, M" uniqKey="Arens M" first="M" last="Arens">M. 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Sagoe</name><affiliation wicri:level="3"><nlm:affiliation>Department of Microbiology, Clinical Virology Laboratory, University of Ghana Medical School, P.O. Box 4236, Accra, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Department of Microbiology, Clinical Virology Laboratory, University of Ghana Medical School, P.O. Box 4236, Accra</wicri:regionArea><placeName><settlement type="city">Accra</settlement><region nuts="2">Région du Grand Accra</region></placeName></affiliation></author><author><name sortKey="Agyei, A A" sort="Agyei, A A" uniqKey="Agyei A" first="A A" last="Agyei">A A Agyei</name></author><author><name sortKey="Lartey, M" sort="Lartey, M" uniqKey="Lartey M" first="M" last="Lartey">M. Lartey</name></author><author><name sortKey="Adiku, T K" sort="Adiku, T K" uniqKey="Adiku T" first="T K" last="Adiku">T K Adiku</name></author><author><name sortKey="Mingle, J A A" sort="Mingle, J A A" uniqKey="Mingle J" first="J A A" last="Mingle">J A A. Mingle</name></author><author><name sortKey="Arens, M" sort="Arens, M" uniqKey="Arens M" first="M" last="Arens">M. Arens</name></author></analytic><series><title level="j">East African medical journal</title><idno type="ISSN">0012-835X</idno><imprint><date when="2009" type="published">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Cross-Sectional Studies</term><term>Developing Countries</term><term>Female</term><term>Ghana</term><term>HIV Seropositivity (diagnosis)</term><term>HIV-1 (immunology)</term><term>HIV-2 (immunology)</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Ghana</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Pays en voie de développement</term><term>Sujet âgé</term><term>Séropositivité VIH (diagnostic)</term><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (immunologie)</term><term>VIH-2 (Virus de l'Immunodéficience Humaine de type 2) (immunologie)</term><term>Études transversales</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Ghana</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>HIV Seropositivity</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Séropositivité VIH</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1)</term><term>VIH-2 (Virus de l'Immunodéficience Humaine de type 2)</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>HIV-1</term><term>HIV-2</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Cross-Sectional Studies</term><term>Developing Countries</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Ghana</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Pays en voie de développement</term><term>Sujet âgé</term><term>Études transversales</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Ghana</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The presence of dual HIV-1/HIV-2 infection in Ghana and the different drug requirements for the treatment of HIV-1 and HIV-2 presents difficulties for the treatment of dual infections with both viruses.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">21644411</PMID><DateCreated><Year>2011</Year><Month>06</Month><Day>07</Day></DateCreated><DateCompleted><Year>2011</Year><Month>07</Month><Day>26</Day></DateCompleted><DateRevised><Year>2011</Year><Month>06</Month><Day>07</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0012-835X</ISSN><JournalIssue CitedMedium="Print"><Volume>86</Volume><Issue>9</Issue><PubDate><Year>2009</Year><Month>Sep</Month></PubDate></JournalIssue><Title>East African medical journal</Title><ISOAbbreviation>East Afr Med J</ISOAbbreviation></Journal><ArticleTitle>Diagnosis of dual human immunodeficiency virus types 1 and 2 infections in a resource-limited setting.</ArticleTitle><Pagination><MedlinePgn>417-21</MedlinePgn></Pagination><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">The presence of dual HIV-1/HIV-2 infection in Ghana and the different drug requirements for the treatment of HIV-1 and HIV-2 presents difficulties for the treatment of dual infections with both viruses.</AbstractText><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">To determine the prevalence of the dual sero-positive profile in treatment naive patients at a principal ART Clinic in Accra, Ghana and to investigate if rapid screening assays could be useful for diagnosis.</AbstractText><AbstractText Label="DESIGN" NlmCategory="METHODS">A cross-sectional study.</AbstractText><AbstractText Label="SETTING" NlmCategory="METHODS">A principal antiretroviral treatment centre in Accra, Ghana.</AbstractText><AbstractText Label="SUBJECTS" NlmCategory="METHODS">Three hundred and twenty eight antiretroviral treatment naive patients.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">A total of 12 (3.7%) of patients seen were dual seropositive. There was a slight tendency of dual seropositive females being older than their HIV-1 counterparts (p = 0.088, CI = -10.833 to 0.753). Eight of the 12 of the dual seropositives were reactive for Genie II and were considered as possibly infected with both HIV-I and HIV-2. Seven (87.5%) of Genie II dual seropositives had strong intensities (> 1+) on both HIV-2 specific bands (sgp105 and gp36) on Innolia. CD4 counts were not significantly different in dual seropositives as compared to HIV-1 infected patients.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Dual HIV-1/HIV-2 seropositives (and possibly infections) maybe common especially in older women. The Genie II will be useful as a supplemental rapid test for rapid and accurate differentiation of HIV-1 and HIV-2 antibodies at treatment centres.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Sagoe</LastName><ForeName>K W C</ForeName><Initials>KW</Initials><AffiliationInfo><Affiliation>Department of Microbiology, Clinical Virology Laboratory, University of Ghana Medical School, P.O. 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Arens</name><name sortKey="Lartey, M" sort="Lartey, M" uniqKey="Lartey M" first="M" last="Lartey">M. Lartey</name><name sortKey="Mingle, J A A" sort="Mingle, J A A" uniqKey="Mingle J" first="J A A" last="Mingle">J A A. Mingle</name></noCountry><country name="Ghana"><region name="Région du Grand Accra"><name sortKey="Sagoe, K W C" sort="Sagoe, K W C" uniqKey="Sagoe K" first="K W C" last="Sagoe">K W C. Sagoe</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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