Assessment of the impact of malaria on CD4+ T Cells and haemoglobin levels of HIV-malaria co-infected patients.
Identifieur interne : 000475 ( PubMed/Checkpoint ); précédent : 000474; suivant : 000476Assessment of the impact of malaria on CD4+ T Cells and haemoglobin levels of HIV-malaria co-infected patients.
Auteurs : Daniel Nii Aryee Tagoe [Ghana] ; Joseph BoachieSource :
- Journal of infection in developing countries [ 1972-2680 ] ; 2012.
Descripteurs français
- KwdFr :
- Adulte, Co-infection (anatomopathologie), Co-infection (immunologie), Femelle, Ghana, Humains, Hémoglobines (analyse), Infections à VIH (), Infections à VIH (anatomopathologie), Infections à VIH (immunologie), Lymphocytes T CD4+ (immunologie), Mâle, Paludisme (), Paludisme (anatomopathologie), Paludisme (immunologie).
- MESH :
- analyse : Hémoglobines.
- anatomopathologie : Co-infection, Infections à VIH, Paludisme.
- immunologie : Co-infection, Infections à VIH, Lymphocytes T CD4+, Paludisme.
- Adulte, Femelle, Ghana, Humains, Infections à VIH, Mâle, Paludisme.
- Wicri :
- geographic : Ghana.
English descriptors
- KwdEn :
- Adult, CD4-Positive T-Lymphocytes (immunology), Coinfection (immunology), Coinfection (pathology), Female, Ghana, HIV Infections (complications), HIV Infections (immunology), HIV Infections (pathology), Hemoglobins (analysis), Humans, Malaria (complications), Malaria (immunology), Malaria (pathology), Male.
- MESH :
- chemical , analysis : Hemoglobins.
- geographic : Ghana.
- complications : HIV Infections, Malaria.
- immunology : CD4-Positive T-Lymphocytes, Coinfection, HIV Infections, Malaria.
- pathology : Coinfection, HIV Infections, Malaria.
- Adult, Female, Humans, Male.
Abstract
The human immunodeficiency virus (HIV) and malaria destroy important cells required for proper immunological and haematological functioning of the body. This research therefore aimed to assess the effect of malaria on CD4+ and haemoglobin (Hb) levels of HIV-malaria co-infected patients.
PubMed: 23000865
Affiliations:
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pubmed:23000865Le document en format XML
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<term>Ghana</term>
<term>HIV Infections (complications)</term>
<term>HIV Infections (immunology)</term>
<term>HIV Infections (pathology)</term>
<term>Hemoglobins (analysis)</term>
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<term>Malaria (complications)</term>
<term>Malaria (immunology)</term>
<term>Malaria (pathology)</term>
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<term>Co-infection (anatomopathologie)</term>
<term>Co-infection (immunologie)</term>
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<term>Ghana</term>
<term>Humains</term>
<term>Hémoglobines (analyse)</term>
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<term>Lymphocytes T CD4+ (immunologie)</term>
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<term>Paludisme ()</term>
<term>Paludisme (anatomopathologie)</term>
<term>Paludisme (immunologie)</term>
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<term>Malaria</term>
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<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Co-infection</term>
<term>Infections à VIH</term>
<term>Lymphocytes T CD4+</term>
<term>Paludisme</term>
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<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>CD4-Positive T-Lymphocytes</term>
<term>Coinfection</term>
<term>HIV Infections</term>
<term>Malaria</term>
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<front><div type="abstract" xml:lang="en">The human immunodeficiency virus (HIV) and malaria destroy important cells required for proper immunological and haematological functioning of the body. This research therefore aimed to assess the effect of malaria on CD4+ and haemoglobin (Hb) levels of HIV-malaria co-infected patients.</div>
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<DateCreated><Year>2012</Year>
<Month>09</Month>
<Day>24</Day>
</DateCreated>
<DateCompleted><Year>2013</Year>
<Month>01</Month>
<Day>31</Day>
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<DateRevised><Year>2012</Year>
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<Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1972-2680</ISSN>
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<Issue>9</Issue>
<PubDate><Year>2012</Year>
<Month>Sep</Month>
<Day>17</Day>
</PubDate>
</JournalIssue>
<Title>Journal of infection in developing countries</Title>
<ISOAbbreviation>J Infect Dev Ctries</ISOAbbreviation>
</Journal>
<ArticleTitle>Assessment of the impact of malaria on CD4+ T Cells and haemoglobin levels of HIV-malaria co-infected patients.</ArticleTitle>
<Pagination><MedlinePgn>660-3</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.3855/jidc.2124</ELocationID>
<Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">The human immunodeficiency virus (HIV) and malaria destroy important cells required for proper immunological and haematological functioning of the body. This research therefore aimed to assess the effect of malaria on CD4+ and haemoglobin (Hb) levels of HIV-malaria co-infected patients.</AbstractText>
<AbstractText Label="METHODOLOGY" NlmCategory="METHODS">The study was performed by sampling 220 adult HIV patients on highly active anti retroviral therapy (HAART) who routinely visited the Tema General Hospital in Ghana. Blood samples were obtained for both blood film microscopy identification of malaria parasites and analysis using rapid diagnostic test kits. A BD Facscount Analyzer was used in the quantification of CD4+ levels.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Of the 220 patients sampled, 34 (15.5%) were HIV-malaria co-infected, all of whom (34; 100%) had CD4+ counts below the normal range, while 23 (12.9%) of the HIV mono-infected patients had normal CD4+ counts. Almost all HIV-malaria co-infected patients (33; 97.1%) had low Hb levels, whereas 79 (42.5%) of the HIV mono-infected patients had normal Hb. Malaria infection strongly correlated positively and significantly with both low CD4+ count (χ2 = 0.828, P = 0.003) and Hb (χ2 = 0.817, P = 0.004) levels.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Malaria co-infection with HIV decreases CD4+ T cells and Hb levels in patients. It is therefore recommended that HIV patients in malaria endemic areas should adhere to malaria preventive measures.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tagoe</LastName>
<ForeName>Daniel Nii Aryee</ForeName>
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<AffiliationInfo><Affiliation>University of Cape Coast, Ghana. dnatagoe@gmail.com</Affiliation>
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<MeshHeading><DescriptorName UI="D015496" MajorTopicYN="N">CD4-Positive T-Lymphocytes</DescriptorName>
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<QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName>
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