Prevalence of hepatitis B virus co-infection among HIV-seropositive persons attending antiretroviral clinics in the Eastern Region of Ghana
Identifieur interne : 000075 ( Pmc/Checkpoint ); précédent : 000074; suivant : 000076Prevalence of hepatitis B virus co-infection among HIV-seropositive persons attending antiretroviral clinics in the Eastern Region of Ghana
Auteurs : Gideon Kye-Duodu [Ghana] ; Priscillia Nortey [Ghana] ; Keziah Malm [Ghana] ; Kofi Mensah Nyarko [Ghana] ; Samuel Oko Sackey [Ghana] ; Sampson Ofori [Ghana] ; Edwin Andrews Afari [Ghana]Source :
- The Pan African Medical Journal [ 1937-8688 ] ; 2016.
Abstract
Hepatitis B and HIV infections are endemic in sub-Saharan Africa including Ghana. Understanding the extent of the co-infection is critical to the optimal care of persons living with HIV and AIDS (PLHIV). We determined the prevalence and risk factors of HBV co-infection in PLHIV and assessed the knowledge of health care workers (HCW) in Antiretroviral Therapy (ART) clinics regarding the co-infection.
A cross sectional study was conducted in five ART clinics to obtain data from a systematic random sample of PLHIV in the Eastern region of Ghana from March to June 2012. We used self-administered questionnaires to assess knowledge of HCW on knowledge and management of the co-infection. Descriptive statistics and logistic regression models were used for analysis at 5% significance level.
Of 320 PLHIV recruited into study, with median age of 40 years (IQR: 33-50 years), 28 tested positive for HBsAg giving an overall prevalence of 8.8%. There were significant associations between HBV infection and being an adult (p=0.004), increasing serum ALT levels (p=0.002) and partner with history of HBV infection (p=0.010). HCW obtained 84.2% (SD± 20.53; 95% CI: 89-98.1) and 53.1% (SD± 35.06; 95% CI: 13.0-88.9) in the “general knowledge” and “management practice” indexes respectively.
Prevalence of HBV-HIV co-infection was relatively high among PLHIV in Eastern region. Knowledge of HCW on management practices of HBV-HIV co-infection and HBV vaccination coverage among PLHIV were found to be relatively low. Regular trainings of HCW and a HBV vaccination programme targeted at PLHIV should be considered.
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DOI: 10.11604/pamj.supp.2016.25.1.6172
PubMed: 28210375
PubMed Central: 5292113
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Box LG 13, Accra</wicri:regionArea><placeName><settlement type="city">Accra</settlement><region nuts="2">Région du Grand Accra</region></placeName><orgName type="university">Université du Ghana</orgName></affiliation></author><author><name sortKey="Malm, Keziah" sort="Malm, Keziah" uniqKey="Malm K" first="Keziah" last="Malm">Keziah Malm</name><affiliation wicri:level="4"><nlm:aff id="aff0001">Ghana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra, Ghana</nlm:aff><country xml:lang="fr">Ghana</country><wicri:regionArea>Ghana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. 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Box LG 13, Accra</wicri:regionArea><placeName><settlement type="city">Accra</settlement><region nuts="2">Région du Grand Accra</region></placeName><orgName type="university">Université du Ghana</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">28210375</idno><idno type="pmc">5292113</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292113</idno><idno type="RBID">PMC:5292113</idno><idno type="doi">10.11604/pamj.supp.2016.25.1.6172</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000504</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000504</idno><idno type="wicri:Area/Pmc/Curation">000503</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000503</idno><idno type="wicri:Area/Pmc/Checkpoint">000075</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000075</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Prevalence of hepatitis B virus co-infection among HIV-seropositive persons attending antiretroviral clinics in the Eastern Region of Ghana</title><author><name sortKey="Kye Duodu, Gideon" sort="Kye Duodu, Gideon" uniqKey="Kye Duodu G" first="Gideon" last="Kye-Duodu">Gideon Kye-Duodu</name><affiliation wicri:level="4"><nlm:aff id="aff0001">Ghana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra, Ghana</nlm:aff><country xml:lang="fr">Ghana</country><wicri:regionArea>Ghana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra</wicri:regionArea><placeName><settlement type="city">Accra</settlement><region nuts="2">Région du Grand Accra</region></placeName><orgName type="university">Université du Ghana</orgName></affiliation></author><author><name sortKey="Nortey, Priscillia" sort="Nortey, Priscillia" uniqKey="Nortey P" first="Priscillia" last="Nortey">Priscillia Nortey</name><affiliation wicri:level="4"><nlm:aff id="aff0002">Department of Epidemiology and Disease Control, School of Public Health, University of Ghana, P.O. Box LG 13, Accra, Ghana</nlm:aff><country xml:lang="fr">Ghana</country><wicri:regionArea>Department of Epidemiology and Disease Control, School of Public Health, University of Ghana, P.O. Box LG 13, Accra</wicri:regionArea><placeName><settlement type="city">Accra</settlement><region nuts="2">Région du Grand Accra</region></placeName><orgName type="university">Université du Ghana</orgName></affiliation></author><author><name sortKey="Malm, Keziah" sort="Malm, Keziah" uniqKey="Malm K" first="Keziah" last="Malm">Keziah Malm</name><affiliation wicri:level="4"><nlm:aff id="aff0001">Ghana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra, Ghana</nlm:aff><country xml:lang="fr">Ghana</country><wicri:regionArea>Ghana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra</wicri:regionArea><placeName><settlement type="city">Accra</settlement><region nuts="2">Région du Grand Accra</region></placeName><orgName type="university">Université du Ghana</orgName></affiliation></author><author><name sortKey="Nyarko, Kofi Mensah" sort="Nyarko, Kofi Mensah" uniqKey="Nyarko K" first="Kofi Mensah" last="Nyarko">Kofi Mensah Nyarko</name><affiliation wicri:level="4"><nlm:aff id="aff0001">Ghana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra, Ghana</nlm:aff><country xml:lang="fr">Ghana</country><wicri:regionArea>Ghana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra</wicri:regionArea><placeName><settlement type="city">Accra</settlement><region nuts="2">Région du Grand Accra</region></placeName><orgName type="university">Université du Ghana</orgName></affiliation></author><author><name sortKey="Sackey, Samuel Oko" sort="Sackey, Samuel Oko" uniqKey="Sackey S" first="Samuel Oko" last="Sackey">Samuel Oko Sackey</name><affiliation wicri:level="4"><nlm:aff id="aff0001">Ghana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra, Ghana</nlm:aff><country xml:lang="fr">Ghana</country><wicri:regionArea>Ghana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra</wicri:regionArea><placeName><settlement type="city">Accra</settlement><region nuts="2">Région du Grand Accra</region></placeName><orgName type="university">Université du Ghana</orgName></affiliation></author><author><name sortKey="Ofori, Sampson" sort="Ofori, Sampson" uniqKey="Ofori S" first="Sampson" last="Ofori">Sampson Ofori</name><affiliation wicri:level="1"><nlm:aff id="aff0003">Ghana Health Service, Regional Hospital, Koforidua, Eastern Region, Ghana</nlm:aff><country xml:lang="fr">Ghana</country><wicri:regionArea>Ghana Health Service, Regional Hospital, Koforidua, Eastern Region</wicri:regionArea><wicri:noRegion>Eastern Region</wicri:noRegion></affiliation></author><author><name sortKey="Afari, Edwin Andrews" sort="Afari, Edwin Andrews" uniqKey="Afari E" first="Edwin Andrews" last="Afari">Edwin Andrews Afari</name><affiliation wicri:level="4"><nlm:aff id="aff0001">Ghana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra, Ghana</nlm:aff><country xml:lang="fr">Ghana</country><wicri:regionArea>Ghana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra</wicri:regionArea><placeName><settlement type="city">Accra</settlement><region nuts="2">Région du Grand Accra</region></placeName><orgName type="university">Université du Ghana</orgName></affiliation></author></analytic><series><title level="j">The Pan African Medical Journal</title><idno type="eISSN">1937-8688</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="s1"><title>Introduction</title><p>Hepatitis B and HIV infections are endemic in sub-Saharan Africa including Ghana. Understanding the extent of the co-infection is critical to the optimal care of persons living with HIV and AIDS (PLHIV). We determined the prevalence and risk factors of HBV co-infection in PLHIV and assessed the knowledge of health care workers (HCW) in Antiretroviral Therapy (ART) clinics regarding the co-infection.</p></sec><sec id="s2"><title>Methods</title><p>A cross sectional study was conducted in five ART clinics to obtain data from a systematic random sample of PLHIV in the Eastern region of Ghana from March to June 2012. We used self-administered questionnaires to assess knowledge of HCW on knowledge and management of the co-infection. Descriptive statistics and logistic regression models were used for analysis at 5% significance level.</p></sec><sec id="s3"><title>Results</title><p>Of 320 PLHIV recruited into study, with median age of 40 years (IQR: 33-50 years), 28 tested positive for HBsAg giving an overall prevalence of 8.8%. There were significant associations between HBV infection and being an adult (p=0.004), increasing serum ALT levels (p=0.002) and partner with history of HBV infection (p=0.010). HCW obtained 84.2% (SD± 20.53; 95% CI: 89-98.1) and 53.1% (SD± 35.06; 95% CI: 13.0-88.9) in the “general knowledge” and “management practice” indexes respectively.</p></sec><sec id="s4"><title>Conclusion</title><p>Prevalence of HBV-HIV co-infection was relatively high among PLHIV in Eastern region. Knowledge of HCW on management practices of HBV-HIV co-infection and HBV vaccination coverage among PLHIV were found to be relatively low. Regular trainings of HCW and a HBV vaccination programme targeted at PLHIV should be considered.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Thio, Cl" uniqKey="Thio C">CL Thio</name></author><author><name sortKey="Seaberg, Ec" uniqKey="Seaberg E">EC Seaberg</name></author><author><name sortKey="Skolasky, R" uniqKey="Skolasky R">R Skolasky</name></author><author><name sortKey="Phair, J" uniqKey="Phair J">J Phair</name></author><author><name sortKey="Visscher, B" uniqKey="Visscher B">B Visscher</name></author><author><name sortKey="Muoz, A" uniqKey="Muoz A">A Muoz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lai, Cl" uniqKey="Lai C">CL Lai</name></author><author><name sortKey="Ratziu, V" uniqKey="Ratziu V">V Ratziu</name></author><author><name sortKey="Yuen, Mf" uniqKey="Yuen M">MF Yuen</name></author><author><name sortKey="Poynard, T" uniqKey="Poynard T">T Poynard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Puoti, M" uniqKey="Puoti M">M Puoti</name></author><author><name sortKey="Airoldi, M" uniqKey="Airoldi M">M Airoldi</name></author><author><name sortKey="Bruno, R" uniqKey="Bruno R">R Bruno</name></author><author><name sortKey="Zanini, B" uniqKey="Zanini B">B Zanini</name></author><author><name sortKey="Spinetti, A" uniqKey="Spinetti A">A Spinetti</name></author><author><name sortKey="Pezzoli, C" uniqKey="Pezzoli C">C Pezzoli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoffmann, Cj" uniqKey="Hoffmann C">CJ Hoffmann</name></author><author><name sortKey="Seaberg, Ec" uniqKey="Seaberg E">EC Seaberg</name></author><author><name sortKey="Young, S" uniqKey="Young S">S Young</name></author><author><name sortKey="Witt, Md" uniqKey="Witt M">MD Witt</name></author><author><name sortKey="Acunto, D" uniqKey="Acunto D">D Acunto</name></author><author><name sortKey="Phair, J" uniqKey="Phair J">J Phair</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Palella, Fj" uniqKey="Palella F">FJ Palella</name></author><author><name sortKey="Baker, Rk" uniqKey="Baker R">RK Baker</name></author><author><name sortKey="Moorman, Ac" uniqKey="Moorman A">AC Moorman</name></author><author><name sortKey="Chmiel, Js" uniqKey="Chmiel J">JS Chmiel</name></author><author><name sortKey="Wood, Kc" uniqKey="Wood K">KC Wood</name></author><author><name sortKey="Brooks, Jt" uniqKey="Brooks J">JT Brooks</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Weber, Rainer" uniqKey="Weber R">Rainer Weber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wester, Cw" uniqKey="Wester C">CW Wester</name></author><author><name sortKey="Bussmann, H" uniqKey="Bussmann H">H Bussmann</name></author><author><name sortKey="Koethe, J" uniqKey="Koethe J">J Koethe</name></author><author><name sortKey="Moffat, C" uniqKey="Moffat C">C Moffat</name></author><author><name sortKey="Vermund, S" uniqKey="Vermund S">S Vermund</name></author><author><name sortKey="Essex, M" uniqKey="Essex M">M Essex</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Konopnicki, D" uniqKey="Konopnicki D">D Konopnicki</name></author><author><name sortKey="Mocroft, A" uniqKey="Mocroft A">A Mocroft</name></author><author><name sortKey="De Wit, S" uniqKey="De Wit S">S de Wit</name></author><author><name sortKey="Antunes, F" uniqKey="Antunes F">F Antunes</name></author><author><name sortKey="Ledergerber, B" uniqKey="Ledergerber B">B Ledergerber</name></author><author><name sortKey="Katlama, C" uniqKey="Katlama C">C Katlama</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lewden, C" uniqKey="Lewden C">C Lewden</name></author><author><name sortKey="May, T" uniqKey="May T">T May</name></author><author><name sortKey="Rosenthal, E" uniqKey="Rosenthal E">E Rosenthal</name></author><author><name sortKey="Burty, C" uniqKey="Burty C">C Burty</name></author><author><name sortKey="Bonnet, F" uniqKey="Bonnet F">F Bonnet</name></author><author><name sortKey="Costagliola, D" uniqKey="Costagliola D">D Costagliola</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Burnett, Rj" uniqKey="Burnett R">RJ Burnett</name></author><author><name sortKey="Francois, G" uniqKey="Francois G">G François</name></author><author><name sortKey="Kew, Mc" uniqKey="Kew M">MC Kew</name></author><author><name sortKey="Leroux Roels, G" uniqKey="Leroux Roels G">G Leroux-Roels</name></author><author><name sortKey="Meheus, A" uniqKey="Meheus A">a Meheus</name></author><author><name sortKey="Hoosen, Aa" uniqKey="Hoosen A">AA Hoosen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Diop Ndiaye, H" uniqKey="Diop Ndiaye H">H Diop-Ndiaye</name></author><author><name sortKey="Toure Kane, C" uniqKey="Toure Kane C">C Touré-Kane</name></author><author><name sortKey="Etard, J F" uniqKey="Etard J">J f Etard</name></author><author><name sortKey="Lo, G" uniqKey="Lo G">G Lô</name></author><author><name sortKey="Diaw, P" uniqKey="Diaw P">P Diaw</name></author><author><name sortKey="Ngom Gueye, N F" uniqKey="Ngom Gueye N">N f Ngom-Gueye</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nyirenda, M" uniqKey="Nyirenda M">M Nyirenda</name></author><author><name sortKey="Beadsworth, Mbj" uniqKey="Beadsworth M">MBJ Beadsworth</name></author><author><name sortKey="Stephany, P" uniqKey="Stephany P">P Stephany</name></author><author><name sortKey="Hart, Ca" uniqKey="Hart C">CA Hart</name></author><author><name sortKey="Hart, Ij" uniqKey="Hart I">IJ Hart</name></author><author><name sortKey="Munthali, C" uniqKey="Munthali C">C Munthali</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kapembwa, Kc" uniqKey="Kapembwa K">KC Kapembwa</name></author><author><name sortKey="Goldman, Jd" uniqKey="Goldman J">JD Goldman</name></author><author><name sortKey="Lakhi, S" uniqKey="Lakhi S">S Lakhi</name></author><author><name sortKey="Banda, Y" uniqKey="Banda Y">Y Banda</name></author><author><name sortKey="Bowa, K" uniqKey="Bowa K">K Bowa</name></author><author><name sortKey="Vermund, Sh" uniqKey="Vermund S">SH Vermund</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Geretti, Am" uniqKey="Geretti A">AM Geretti</name></author><author><name sortKey="Patel, M" uniqKey="Patel M">M Patel</name></author><author><name sortKey="Sarfo, Fs" uniqKey="Sarfo F">FS Sarfo</name></author><author><name sortKey="Chadwick, D" uniqKey="Chadwick D">D Chadwick</name></author><author><name sortKey="Verheyen, J" uniqKey="Verheyen J">J Verheyen</name></author><author><name sortKey="Fraune, M" uniqKey="Fraune M">M Fraune</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Agency, Gn" uniqKey="Agency G">GN Agency</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Chao, J" uniqKey="Chao J">J Chao</name></author><author><name sortKey="Chang, Et" uniqKey="Chang E">ET Chang</name></author><author><name sortKey="So, Sk" uniqKey="So S">SK So</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Samuel, So" uniqKey="Samuel S">SO Samuel</name></author><author><name sortKey="Aderibigbe, Sa" uniqKey="Aderibigbe S">SA Aderibigbe</name></author><author><name sortKey="Salami, Tat" uniqKey="Salami T">TAT Salami</name></author><author><name sortKey="Babatunde, Oa" uniqKey="Babatunde O">OA Babatunde</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Nyonator, F" uniqKey="Nyonator F">F Nyonator</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Singh, A" uniqKey="Singh A">A Singh</name></author><author><name sortKey="Masuku, M" uniqKey="Masuku M">M Masuku</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Israel, Gd" uniqKey="Israel G">GD Israel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nagu, Tj" uniqKey="Nagu T">TJ Nagu</name></author><author><name sortKey="Bakari, M" uniqKey="Bakari M">M Bakari</name></author><author><name sortKey="Matee, M" uniqKey="Matee M">M Matee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wester, Cw" uniqKey="Wester C">CW Wester</name></author><author><name sortKey="Bussmann, H" uniqKey="Bussmann H">H Bussmann</name></author><author><name sortKey="Koethe, J" uniqKey="Koethe J">J Koethe</name></author><author><name sortKey="Moffat, C" uniqKey="Moffat C">C Moffat</name></author><author><name sortKey="Vermund, S" uniqKey="Vermund S">S Vermund</name></author><author><name sortKey="Essex, M" uniqKey="Essex M">M Essex</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Blankson, A" uniqKey="Blankson A">A Blankson</name></author><author><name sortKey="Wiredu, Ek" uniqKey="Wiredu E">EK Wiredu</name></author><author><name sortKey="Gyasi, Rk" uniqKey="Gyasi R">RK Gyasi</name></author><author><name sortKey="Adjei, A" uniqKey="Adjei A">A Adjei</name></author><author><name sortKey="Tettey, Y" uniqKey="Tettey Y">Y Tettey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shimelis, T" uniqKey="Shimelis T">T Shimelis</name></author><author><name sortKey="Torben, W" uniqKey="Torben W">W Torben</name></author><author><name sortKey="Medhin, G" uniqKey="Medhin G">G Medhin</name></author><author><name sortKey="Tebeje, M" uniqKey="Tebeje M">M Tebeje</name></author><author><name sortKey="Andualm, A" uniqKey="Andualm A">A Andualm</name></author><author><name sortKey="Demessie, F" uniqKey="Demessie F">F Demessie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Moore, E" uniqKey="Moore E">E Moore</name></author><author><name sortKey="Beadsworth, Mbj" uniqKey="Beadsworth M">MBJ Beadsworth</name></author><author><name sortKey="Chaponda, M" uniqKey="Chaponda M">M Chaponda</name></author><author><name sortKey="Mhango, B" uniqKey="Mhango B">B Mhango</name></author><author><name sortKey="Faragher, B" uniqKey="Faragher B">B Faragher</name></author><author><name sortKey="Njala, J" uniqKey="Njala J">J Njala</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Braga, Wsm" uniqKey="Braga W">WSM Braga</name></author><author><name sortKey="Castilho, M Da C" uniqKey="Castilho M">M da C Castilho</name></author><author><name sortKey="Santos, Icv Dos" uniqKey="Santos I">ICV dos Santos</name></author><author><name sortKey="Moura, Mas" uniqKey="Moura M">MAS Moura</name></author><author><name sortKey="Segurado, Ac" uniqKey="Segurado A">AC Segurado</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Adewole, Oo" uniqKey="Adewole O">OO Adewole</name></author><author><name sortKey="Anteyi, E" uniqKey="Anteyi E">E Anteyi</name></author><author><name sortKey="Ajuwon, Z" uniqKey="Ajuwon Z">Z Ajuwon</name></author><author><name sortKey="Wada, I" uniqKey="Wada I">I Wada</name></author><author><name sortKey="Elegba, F" uniqKey="Elegba F">F Elegba</name></author><author><name sortKey="Ahmed, P" uniqKey="Ahmed P">P Ahmed</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pereira, Rar De A" uniqKey="Pereira R">RAR de A Pereira</name></author><author><name sortKey="Mussi, Adh" uniqKey="Mussi A">ADH Mussi</name></author><author><name sortKey="Silva, Vc De Ae" uniqKey="Silva V">VC de AE Silva</name></author><author><name sortKey="Souto, Fj" uniqKey="Souto F">FJ Souto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mehmet, D" uniqKey="Mehmet D">D Mehmet</name></author><author><name sortKey="Meliksah, E" uniqKey="Meliksah E">E Meliksah</name></author><author><name sortKey="Serif, Y" uniqKey="Serif Y">Y Serif</name></author><author><name sortKey="Gunay, S" uniqKey="Gunay S">S Gunay</name></author><author><name sortKey="Tuncer, O" uniqKey="Tuncer O">Ö Tuncer</name></author><author><name sortKey="Zeynep, S" uniqKey="Zeynep S">S Zeynep</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reid, Sr" uniqKey="Reid S">SR Reid</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Irving, A" uniqKey="Irving A">A Irving</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ziraba, Ak" uniqKey="Ziraba A">AK Ziraba</name></author><author><name sortKey="Bwogi, J" uniqKey="Bwogi J">J Bwogi</name></author><author><name sortKey="Namale, A" uniqKey="Namale A">A Namale</name></author><author><name sortKey="Wainaina, Cw" uniqKey="Wainaina C">CW Wainaina</name></author><author><name sortKey="Mayanja Kizza, H" uniqKey="Mayanja Kizza H">H Mayanja-Kizza</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Pan Afr Med J</journal-id><journal-id journal-id-type="iso-abbrev">Pan Afr Med J</journal-id><journal-id journal-id-type="publisher-id">PAMJ</journal-id><journal-title-group><journal-title>The Pan African Medical Journal</journal-title></journal-title-group><issn pub-type="epub">1937-8688</issn><publisher><publisher-name>The African Field Epidemiology Network</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">28210375</article-id><article-id pub-id-type="pmc">5292113</article-id><article-id pub-id-type="publisher-id">PAMJ-SUPP-25-1-07</article-id><article-id pub-id-type="doi">10.11604/pamj.supp.2016.25.1.6172</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research</subject></subj-group></article-categories><title-group><article-title>Prevalence of hepatitis B virus co-infection among HIV-seropositive persons attending antiretroviral clinics in the Eastern Region of Ghana</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Kye-Duodu</surname><given-names>Gideon</given-names></name><xref ref-type="aff" rid="aff0001">1</xref><xref ref-type="corresp" rid="cor1">&</xref></contrib><contrib contrib-type="author"><name><surname>Nortey</surname><given-names>Priscillia</given-names></name><xref ref-type="aff" rid="aff0002">2</xref></contrib><contrib contrib-type="author"><name><surname>Malm</surname><given-names>Keziah</given-names></name><xref ref-type="aff" rid="aff0001">1</xref></contrib><contrib contrib-type="author"><name><surname>Nyarko</surname><given-names>Kofi Mensah</given-names></name><xref ref-type="aff" rid="aff0001">1</xref></contrib><contrib contrib-type="author"><name><surname>Sackey</surname><given-names>Samuel Oko</given-names></name><xref ref-type="aff" rid="aff0001">1</xref></contrib><contrib contrib-type="author"><name><surname>Ofori</surname><given-names>Sampson</given-names></name><xref ref-type="aff" rid="aff0003">3</xref></contrib><contrib contrib-type="author"><name><surname>Afari</surname><given-names>Edwin Andrews</given-names></name><xref ref-type="aff" rid="aff0001">1</xref></contrib></contrib-group><aff id="aff0001"><label>1</label>Ghana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra, Ghana</aff><aff id="aff0002"><label>2</label>Department of Epidemiology and Disease Control, School of Public Health, University of Ghana, P.O. Box LG 13, Accra, Ghana</aff><aff id="aff0003"><label>3</label>Ghana Health Service, Regional Hospital, Koforidua, Eastern Region, Ghana</aff><author-notes><corresp id="cor1"><label>&</label><bold>Corresponding author:</bold> Gideon Kye-Duodu, Ghana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra, Ghana. (<email xlink:href="kyedors@yahoo.com">kyedors@yahoo.com</email>)</corresp></author-notes><pub-date pub-type="epub"><day>01</day><month>10</month><year>2016</year></pub-date><pub-date pub-type="collection"><year>2016</year></pub-date><volume>25</volume><issue>Suppl 1</issue><elocation-id>7</elocation-id><history><date date-type="received"><day>22</day><month>1</month><year>2015</year></date><date date-type="accepted"><day>06</day><month>6</month><year>2016</year></date></history><permissions><copyright-statement>© Gideon Kye-Duodu et al.</copyright-statement><copyright-year>2016</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/2.0/"><license-p>The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><sec id="s1"><title>Introduction</title><p>Hepatitis B and HIV infections are endemic in sub-Saharan Africa including Ghana. Understanding the extent of the co-infection is critical to the optimal care of persons living with HIV and AIDS (PLHIV). We determined the prevalence and risk factors of HBV co-infection in PLHIV and assessed the knowledge of health care workers (HCW) in Antiretroviral Therapy (ART) clinics regarding the co-infection.</p></sec><sec id="s2"><title>Methods</title><p>A cross sectional study was conducted in five ART clinics to obtain data from a systematic random sample of PLHIV in the Eastern region of Ghana from March to June 2012. We used self-administered questionnaires to assess knowledge of HCW on knowledge and management of the co-infection. Descriptive statistics and logistic regression models were used for analysis at 5% significance level.</p></sec><sec id="s3"><title>Results</title><p>Of 320 PLHIV recruited into study, with median age of 40 years (IQR: 33-50 years), 28 tested positive for HBsAg giving an overall prevalence of 8.8%. There were significant associations between HBV infection and being an adult (p=0.004), increasing serum ALT levels (p=0.002) and partner with history of HBV infection (p=0.010). HCW obtained 84.2% (SD± 20.53; 95% CI: 89-98.1) and 53.1% (SD± 35.06; 95% CI: 13.0-88.9) in the “general knowledge” and “management practice” indexes respectively.</p></sec><sec id="s4"><title>Conclusion</title><p>Prevalence of HBV-HIV co-infection was relatively high among PLHIV in Eastern region. Knowledge of HCW on management practices of HBV-HIV co-infection and HBV vaccination coverage among PLHIV were found to be relatively low. Regular trainings of HCW and a HBV vaccination programme targeted at PLHIV should be considered.</p></sec></abstract><kwd-group><kwd>Human Immunodeficiency Virus</kwd><kwd>hepatitis B virus</kwd><kwd>co-infection</kwd><kwd>risk factors</kwd><kwd>Ghana</kwd></kwd-group></article-meta></front></pmc><affiliations><list><country><li>Ghana</li></country><region><li>Région du Grand Accra</li></region><settlement><li>Accra</li></settlement><orgName><li>Université du Ghana</li></orgName></list><tree><country name="Ghana"><region name="Région du Grand Accra"><name sortKey="Kye Duodu, Gideon" sort="Kye Duodu, Gideon" uniqKey="Kye Duodu G" first="Gideon" last="Kye-Duodu">Gideon Kye-Duodu</name></region><name sortKey="Afari, Edwin Andrews" sort="Afari, Edwin Andrews" uniqKey="Afari E" first="Edwin Andrews" last="Afari">Edwin Andrews Afari</name><name sortKey="Malm, Keziah" sort="Malm, Keziah" uniqKey="Malm K" first="Keziah" last="Malm">Keziah Malm</name><name sortKey="Nortey, Priscillia" sort="Nortey, Priscillia" uniqKey="Nortey P" first="Priscillia" last="Nortey">Priscillia Nortey</name><name sortKey="Nyarko, Kofi Mensah" sort="Nyarko, Kofi Mensah" uniqKey="Nyarko K" first="Kofi Mensah" last="Nyarko">Kofi Mensah Nyarko</name><name sortKey="Ofori, Sampson" sort="Ofori, Sampson" uniqKey="Ofori S" first="Sampson" last="Ofori">Sampson Ofori</name><name sortKey="Sackey, Samuel Oko" sort="Sackey, Samuel Oko" uniqKey="Sackey S" first="Samuel Oko" last="Sackey">Samuel Oko Sackey</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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