SidaGhanaV1, PascalFrancis, Curation, bibRecord, 000100

Low seroprevalence of cryptococcal antigenaemia in patients with advanced HIV infection enrolling in an antiretroviral programme in Ghana

Identifieur interne : 000100 ( PascalFrancis/Curation ); précédent : 000099; suivant : 000101

Low seroprevalence of cryptococcal antigenaemia in patients with advanced HIV infection enrolling in an antiretroviral programme in Ghana

Auteurs : Yaasir Mamoojee [Royaume-Uni] ; Shaid Shakoor [Royaume-Uni] ; Rebecca L. Gorton [Royaume-Uni] ; Stephen Sarfo [Ghana] ; Lambert T. Appiah [Ghana] ; Betty Norman [Ghana] ; Indran Balakrishnan [Royaume-Uni] ; Richard Phillips [Ghana] ; David Chadwick [Royaume-Uni]

Source :

TM & IH. Tropical medicine & international health [ 1360-2276 ] ; 2011.

RBID : Pascal:11-0033262

Descripteurs français

Pascal (Inist)
- SIDA, Sérologie, Antiviral, Prévalence, Cryptococcose, Antigène, Homme, Virus immunodéficience humaine, Sang, Stade avancé, Antirétroviral, Ghana, Epidémiologie, Médecine tropicale.
Wicri :
- geographic : Ghana.
- topic : Homme.

English descriptors

KwdEn :
- AIDS, Advanced stage, Antigen, Antiretroviral agent, Antiviral, Blood, Cryptococcosis, Epidemiology, Ghana, Human, Human immunodeficiency virus, Prevalence, Serology, Tropical medicine.

Abstract

OBJECTIVES To determine the prevalence of cryptococcal antigenaemia in a clinic population with advanced HIV infection, with a view to giving antifungal therapy to those testing positive. METHODS Serum samples from adults with CD4 count <100 cells/mm³ presenting to a large HIV clinic in Kumasi, Ghana, were tested retrospectively for cryptococcal antigenaemia using a latex agglutination assay, and clinical and demographic data extracted from case notes. RESULTS Of 92 samples tested, two were positive thus giving a prevalence of 2% (95% CI, 0-5.2%). CONCLUSIONS The prevalence of cryptococcal antigenaemia in patients with advanced HIV infection enrolling in an antiretroviral programme appears to be low in Kumasi, suggesting that the value of routine testing of outpatients diagnosed with advanced HIV infection may be limited in this population.

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A14	`03`			`@1 Department of Medicine, Komfo Anokye Teaching Hospital @2 Kumasi @3 GHA @Z 4 aut. @Z 5 aut. @Z 6 aut. @Z 8 aut.`
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C01	`01`		`ENG`	@0 OBJECTIVES To determine the prevalence of cryptococcal antigenaemia in a clinic population with advanced HIV infection, with a view to giving antifungal therapy to those testing positive. METHODS Serum samples from adults with CD4 count <100 cells/mm³ presenting to a large HIV clinic in Kumasi, Ghana, were tested retrospectively for cryptococcal antigenaemia using a latex agglutination assay, and clinical and demographic data extracted from case notes. RESULTS Of 92 samples tested, two were positive thus giving a prevalence of 2% (95% CI, 0-5.2%). CONCLUSIONS The prevalence of cryptococcal antigenaemia in patients with advanced HIV infection enrolling in an antiretroviral programme appears to be low in Kumasi, suggesting that the value of routine testing of outpatients diagnosed with advanced HIV infection may be limited in this population.
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Pascal:11-0033262

Le document en format XML

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<s2>London</s2>
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<author><name sortKey="Phillips, Richard" sort="Phillips, Richard" uniqKey="Phillips R" first="Richard" last="Phillips">Richard Phillips</name>
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<series><title level="j" type="main">TM & IH. Tropical medicine & international health</title>
<title level="j" type="abbreviated">TM IH, Trop. med. int. health</title>
<idno type="ISSN">1360-2276</idno>
<imprint><date when="2011">2011</date>
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<seriesStmt><title level="j" type="main">TM & IH. Tropical medicine & international health</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>AIDS</term>
<term>Advanced stage</term>
<term>Antigen</term>
<term>Antiretroviral agent</term>
<term>Antiviral</term>
<term>Blood</term>
<term>Cryptococcosis</term>
<term>Epidemiology</term>
<term>Ghana</term>
<term>Human</term>
<term>Human immunodeficiency virus</term>
<term>Prevalence</term>
<term>Serology</term>
<term>Tropical medicine</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>SIDA</term>
<term>Sérologie</term>
<term>Antiviral</term>
<term>Prévalence</term>
<term>Cryptococcose</term>
<term>Antigène</term>
<term>Homme</term>
<term>Virus immunodéficience humaine</term>
<term>Sang</term>
<term>Stade avancé</term>
<term>Antirétroviral</term>
<term>Ghana</term>
<term>Epidémiologie</term>
<term>Médecine tropicale</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Ghana</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term>
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<front><div type="abstract" xml:lang="en">OBJECTIVES To determine the prevalence of cryptococcal antigenaemia in a clinic population with advanced HIV infection, with a view to giving antifungal therapy to those testing positive. METHODS Serum samples from adults with CD4 count <100 cells/mm<sup>3</sup>
 presenting to a large HIV clinic in Kumasi, Ghana, were tested retrospectively for cryptococcal antigenaemia using a latex agglutination assay, and clinical and demographic data extracted from case notes. RESULTS Of 92 samples tested, two were positive thus giving a prevalence of 2% (95% CI, 0-5.2%). CONCLUSIONS The prevalence of cryptococcal antigenaemia in patients with advanced HIV infection enrolling in an antiretroviral programme appears to be low in Kumasi, suggesting that the value of routine testing of outpatients diagnosed with advanced HIV infection may be limited in this population.</div>
</front>
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<fA03 i2="1"><s0>TM IH, Trop. med. int. health</s0>
</fA03>
<fA05><s2>16</s2>
</fA05>
<fA06><s2>1</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>Low seroprevalence of cryptococcal antigenaemia in patients with advanced HIV infection enrolling in an antiretroviral programme in Ghana</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>MAMOOJEE (Yaasir)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>SHAKOOR (Shaid)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>GORTON (Rebecca L.)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>SARFO (Stephen)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>APPIAH (Lambert T.)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>NORMAN (Betty)</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>BALAKRISHNAN (Indran)</s1>
</fA11>
<fA11 i1="08" i2="1"><s1>PHILLIPS (Richard)</s1>
</fA11>
<fA11 i1="09" i2="1"><s1>CHADWICK (David)</s1>
</fA11>
<fA14 i1="01"><s1>Department of Infection & Travel Medicine, The James Cook University Hospital</s1>
<s2>Middlesbrough</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>9 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Department of Microbiology, The Royal Free Hospital</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>3 aut.</sZ>
<sZ>7 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Department of Medicine, Komfo Anokye Teaching Hospital</s1>
<s2>Kumasi</s2>
<s3>GHA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</fA14>
<fA20><s1>53-56</s1>
</fA20>
<fA21><s1>2011</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>26295</s2>
<s5>354000194051910070</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2011 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>1/2 p.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>11-0033262</s0>
</fA47>
<fA60><s1>P</s1>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>TM & IH. Tropical medicine & international health</s0>
</fA64>
<fA66 i1="01"><s0>GBR</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>OBJECTIVES To determine the prevalence of cryptococcal antigenaemia in a clinic population with advanced HIV infection, with a view to giving antifungal therapy to those testing positive. METHODS Serum samples from adults with CD4 count <100 cells/mm<sup>3</sup>
 presenting to a large HIV clinic in Kumasi, Ghana, were tested retrospectively for cryptococcal antigenaemia using a latex agglutination assay, and clinical and demographic data extracted from case notes. RESULTS Of 92 samples tested, two were positive thus giving a prevalence of 2% (95% CI, 0-5.2%). CONCLUSIONS The prevalence of cryptococcal antigenaemia in patients with advanced HIV infection enrolling in an antiretroviral programme appears to be low in Kumasi, suggesting that the value of routine testing of outpatients diagnosed with advanced HIV infection may be limited in this population.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B01</s0>
</fC02>
<fC02 i1="02" i2="X"><s0>002B05D02L</s0>
</fC02>
<fC02 i1="03" i2="X"><s0>002B05C02D</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>SIDA</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>AIDS</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>SIDA</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Sérologie</s0>
<s5>04</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Serology</s0>
<s5>04</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Serología</s0>
<s5>04</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Antiviral</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Antiviral</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Antiviral</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Prévalence</s0>
<s5>07</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Prevalence</s0>
<s5>07</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Prevalencia</s0>
<s5>07</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Cryptococcose</s0>
<s5>08</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Cryptococcosis</s0>
<s5>08</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Criptococosis</s0>
<s5>08</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Antigène</s0>
<s5>09</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Antigen</s0>
<s5>09</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Antígeno</s0>
<s5>09</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Homme</s0>
<s5>10</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Human</s0>
<s5>10</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Hombre</s0>
<s5>10</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Virus immunodéficience humaine</s0>
<s2>NW</s2>
<s5>11</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Human immunodeficiency virus</s0>
<s2>NW</s2>
<s5>11</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Human immunodeficiency virus</s0>
<s2>NW</s2>
<s5>11</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Sang</s0>
<s5>13</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Blood</s0>
<s5>13</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Sangre</s0>
<s5>13</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Stade avancé</s0>
<s5>14</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Advanced stage</s0>
<s5>14</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Estadio avanzado</s0>
<s5>14</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Antirétroviral</s0>
<s5>15</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG"><s0>Antiretroviral agent</s0>
<s5>15</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA"><s0>Antiretroviral</s0>
<s5>15</s5>
</fC03>
<fC03 i1="12" i2="X" l="FRE"><s0>Ghana</s0>
<s2>NG</s2>
<s5>16</s5>
</fC03>
<fC03 i1="12" i2="X" l="ENG"><s0>Ghana</s0>
<s2>NG</s2>
<s5>16</s5>
</fC03>
<fC03 i1="12" i2="X" l="SPA"><s0>Ghana</s0>
<s2>NG</s2>
<s5>16</s5>
</fC03>
<fC03 i1="13" i2="X" l="FRE"><s0>Epidémiologie</s0>
<s5>18</s5>
</fC03>
<fC03 i1="13" i2="X" l="ENG"><s0>Epidemiology</s0>
<s5>18</s5>
</fC03>
<fC03 i1="13" i2="X" l="SPA"><s0>Epidemiología</s0>
<s5>18</s5>
</fC03>
<fC03 i1="14" i2="X" l="FRE"><s0>Médecine tropicale</s0>
<s5>19</s5>
</fC03>
<fC03 i1="14" i2="X" l="ENG"><s0>Tropical medicine</s0>
<s5>19</s5>
</fC03>
<fC03 i1="14" i2="X" l="SPA"><s0>Medicina tropical</s0>
<s5>19</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Virose</s0>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Viral disease</s0>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Virosis</s0>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Infection</s0>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Infection</s0>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Infección</s0>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Mycose</s0>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Mycosis</s0>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Micosis</s0>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Lentivirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Lentivirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Lentivirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Retroviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Retroviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Retroviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="07" i2="X" l="FRE"><s0>Afrique</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="07" i2="X" l="ENG"><s0>Africa</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="07" i2="X" l="SPA"><s0>Africa</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="08" i2="X" l="FRE"><s0>Immunodéficit</s0>
<s5>37</s5>
</fC07>
<fC07 i1="08" i2="X" l="ENG"><s0>Immune deficiency</s0>
<s5>37</s5>
</fC07>
<fC07 i1="08" i2="X" l="SPA"><s0>Inmunodeficiencia</s0>
<s5>37</s5>
</fC07>
<fC07 i1="09" i2="X" l="FRE"><s0>Immunopathologie</s0>
<s5>39</s5>
</fC07>
<fC07 i1="09" i2="X" l="ENG"><s0>Immunopathology</s0>
<s5>39</s5>
</fC07>
<fC07 i1="09" i2="X" l="SPA"><s0>Inmunopatología</s0>
<s5>39</s5>
</fC07>
<fN21><s1>024</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>

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	Le SIDA au Ghana (serveur d'exploration)
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Le SIDA au Ghana (serveur d'exploration)

Low seroprevalence of cryptococcal antigenaemia in patients with advanced HIV infection enrolling in an antiretroviral programme in Ghana

Low seroprevalence of cryptococcal antigenaemia in patients with advanced HIV infection enrolling in an antiretroviral programme in Ghana

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