SidaGhanaV1, PascalFrancis, Curation, bibRecord, 000090

Relative safety of first-time volunteer and replacement donors in West Africa

Identifieur interne : 000090 ( PascalFrancis/Curation ); précédent : 000089; suivant : 000091

Relative safety of first-time volunteer and replacement donors in West Africa

Auteurs : Jean-Pierre Allain [Royaume-Uni, Ghana] ; Francis Sarkodie ; Kwame Asenso-Mensah ; Shirley Owusu-Ofori

Source :

Transfusion : (Philadelphia, PA) [ 0041-1132 ] ; 2010.

RBID : Pascal:10-0108406

Descripteurs français

Pascal (Inist)
- Homme, Donneur limite, Afrique, Transfusion.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Africa, Human, Suboptimal donor, Transfusion.

Abstract

BACKGROUND: A significantly higher level of safety between nonremunerated volunteer and replacement donor blood is assumed. This is supported by global data without stratifying between genuine replacement and paid donors, for first-time or repeat volunteer, or according to age. STUDY DESIGN AND METHODS: In 2008, first-time volunteer and replacement donors were identified, and confirmed human immunodeficiency virus antibody (anti-HIV), hepatitis B surface antigen (HBsAg), and hepatitis C virus antibody (anti-HCV)-positive screening results were collated. Data were analyzed according to age and sex between the two types of donors. RESULTS: In 6640 first-time volunteer and 4360 replacement donors, the prevalence of anti-HIV and HBsAg (1.03 and 13.8% vs. 1.1 and 14.9%, respectively) was not significantly different. Anti-HIV prevalence was higher in replacement donors less than age 20 than in first-time volunteers; the difference was not significant. HBsAg and anti-HIV confirmed-positive prevalence was significantly higher in first-time volunteer donors over age 20. CONCLUSION: In Kumasi, Ghana, viral safety of replacement and first-time volunteer donors was similar, constituting a single population of donors. Safety increment is provided by repeat donation applicable to either group, through different approaches. A blood unit from replacement donor costs half or less than that from a volunteer donor; similar studies conducted elsewhere in sub-Saharan Africa may lead to changes in current strategies.

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A08	`01`	`1`	`ENG`	`@1 Relative safety of first-time volunteer and replacement donors in West Africa`
A11	`01`	`1`		`@1 ALLAIN (Jean-Pierre)`
A11	`02`	`1`		`@1 SARKODIE (Francis)`
A11	`03`	`1`		`@1 ASENSO-MENSAH (Kwame)`
A11	`04`	`1`		`@1 OWUSU-OFORI (Shirley)`
A14	`01`			`@1 Division of Transfusion Medicine, Department of Haematology, University of Cambridge @2 Cambridge @3 GBR`
A14	`02`			`@1 Transfusion Medicine Unit, Komfo Anokye Teaching Hospital @2 Kumasi @3 GHA`
A20				`@1 340-343`
A21				`@1 2010`
A23	`01`			`@0 ENG`
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C01	`01`		`ENG`	@0 BACKGROUND: A significantly higher level of safety between nonremunerated volunteer and replacement donor blood is assumed. This is supported by global data without stratifying between genuine replacement and paid donors, for first-time or repeat volunteer, or according to age. STUDY DESIGN AND METHODS: In 2008, first-time volunteer and replacement donors were identified, and confirmed human immunodeficiency virus antibody (anti-HIV), hepatitis B surface antigen (HBsAg), and hepatitis C virus antibody (anti-HCV)-positive screening results were collated. Data were analyzed according to age and sex between the two types of donors. RESULTS: In 6640 first-time volunteer and 4360 replacement donors, the prevalence of anti-HIV and HBsAg (1.03 and 13.8% vs. 1.1 and 14.9%, respectively) was not significantly different. Anti-HIV prevalence was higher in replacement donors less than age 20 than in first-time volunteers; the difference was not significant. HBsAg and anti-HIV confirmed-positive prevalence was significantly higher in first-time volunteer donors over age 20. CONCLUSION: In Kumasi, Ghana, viral safety of replacement and first-time volunteer donors was similar, constituting a single population of donors. Safety increment is provided by repeat donation applicable to either group, through different approaches. A blood unit from replacement donor costs half or less than that from a volunteer donor; similar studies conducted elsewhere in sub-Saharan Africa may lead to changes in current strategies.
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C03	`02`	`X`	`ENG`	`@0 Suboptimal donor @5 10`
C03	`02`	`X`	`SPA`	`@0 Donante marginal @5 10`
C03	`03`	`X`	`FRE`	`@0 Afrique @2 NG @5 11`
C03	`03`	`X`	`ENG`	`@0 Africa @2 NG @5 11`
C03	`03`	`X`	`SPA`	`@0 Africa @2 NG @5 11`
C03	`04`	`X`	`FRE`	`@0 Transfusion @5 12`
C03	`04`	`X`	`ENG`	`@0 Transfusion @5 12`
C03	`04`	`X`	`SPA`	`@0 Transfusión @5 12`
N21				`@1 067`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

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Pascal:10-0108406

Le document en format XML

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<author><name sortKey="Allain, Jean Pierre" sort="Allain, Jean Pierre" uniqKey="Allain J" first="Jean-Pierre" last="Allain">Jean-Pierre Allain</name>
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<author><name sortKey="Asenso Mensah, Kwame" sort="Asenso Mensah, Kwame" uniqKey="Asenso Mensah K" first="Kwame" last="Asenso-Mensah">Kwame Asenso-Mensah</name>
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<author><name sortKey="Owusu Ofori, Shirley" sort="Owusu Ofori, Shirley" uniqKey="Owusu Ofori S" first="Shirley" last="Owusu-Ofori">Shirley Owusu-Ofori</name>
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<front><div type="abstract" xml:lang="en">BACKGROUND: A significantly higher level of safety between nonremunerated volunteer and replacement donor blood is assumed. This is supported by global data without stratifying between genuine replacement and paid donors, for first-time or repeat volunteer, or according to age. STUDY DESIGN AND METHODS: In 2008, first-time volunteer and replacement donors were identified, and confirmed human immunodeficiency virus antibody (anti-HIV), hepatitis B surface antigen (HBsAg), and hepatitis C virus antibody (anti-HCV)-positive screening results were collated. Data were analyzed according to age and sex between the two types of donors. RESULTS: In 6640 first-time volunteer and 4360 replacement donors, the prevalence of anti-HIV and HBsAg (1.03 and 13.8% vs. 1.1 and 14.9%, respectively) was not significantly different. Anti-HIV prevalence was higher in replacement donors less than age 20 than in first-time volunteers; the difference was not significant. HBsAg and anti-HIV confirmed-positive prevalence was significantly higher in first-time volunteer donors over age 20. CONCLUSION: In Kumasi, Ghana, viral safety of replacement and first-time volunteer donors was similar, constituting a single population of donors. Safety increment is provided by repeat donation applicable to either group, through different approaches. A blood unit from replacement donor costs half or less than that from a volunteer donor; similar studies conducted elsewhere in sub-Saharan Africa may lead to changes in current strategies.</div>
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	Le SIDA au Ghana (serveur d'exploration)
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Le SIDA au Ghana (serveur d'exploration)

Relative safety of first-time volunteer and replacement donors in West Africa

Relative safety of first-time volunteer and replacement donors in West Africa

Source :

Descripteurs français

English descriptors

Abstract

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