SidaGhanaV1, PascalFrancis, Curation, bibRecord, 000010

Residual risk of transfusion in Ghana

Identifieur interne : 000010 ( PascalFrancis/Curation ); précédent : 000009; suivant : 000011

Residual risk of transfusion in Ghana

Auteurs : Daniel Candotti [Royaume-Uni] ; Francis Sarkodie [Ghana] ; Jean-Pierre Allain [Royaume-Uni]

Source :

British journal of haematology [ 0007-1048 ] ; 2001.

RBID : Pascal:01-0325633

Descripteurs français

Pascal (Inist)
- Transfusion, Sécurité transfusionnelle, Donneur sang, Virus immunodéficience humaine, Virus hépatite C, Risque infectieux, Homme.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Blood donor, Hepatitis C virus, Human, Human immunodeficiency virus, Infectious risk, Transfusion, Transfusion safety.

Abstract

Plasma samples from replacement and volunteer blood donors in Kumasi, Ghana were pooled and tested using a duplex human immunodeficiency virus (HIV) and hepatitis C virus (HCV) RNA detection method. Individual plasmas constitutive of reactive pools were confirmed using reverse transcription-polymerase chain reaction. HIV and HCV infections were significantly higher in 1569 replacement donors than in 1169 volunteers; 2.4 and 1.7 versus 0.3 and 0.7% respectively (P < 0.01). Two duplex RNA-positive plasma pools contained a confirmed/seronegative HIV or HCV RNA individual plasma. The residual post-transfusion risk of HIV and HCV infection of blood collected from replacement blood donors ranged between 1:260 and 1:16 393 after screening for anti-HIV p24 antigen and anti-HCV, These data indicate that in high-prevalence HIV and HCV blood donor populations, a substantial residual post-transfusion risk of infection remains. This risk might be reduced by collecting blood in younger volunteer donors or by genomic screening.

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A02	`01`			`@0 BJHEAL`
A03		`1`		`@0 Br. j. haematol.`
A05				`@2 113`
A06				`@2 1`
A08	`01`	`1`	`ENG`	`@1 Residual risk of transfusion in Ghana`
A11	`01`	`1`		`@1 CANDOTTI (Daniel)`
A11	`02`	`1`		`@1 SARKODIE (Francis)`
A11	`03`	`1`		`@1 ALLAIN (Jean-Pierre)`
A14	`01`			`@1 East Anglia Blood Centre, National Blood Service @2 Cambridge @3 GBR @Z 1 aut.`
A14	`02`			`@1 Department of Medicine, Komfo Anokye Teaching Hospital @2 Kumasi @3 GHA @Z 2 aut.`
A14	`03`			`@1 Division of Transfusion Medicine, Department of Haematology, University of Cambridge @2 Cambridge @3 GBR @Z 3 aut.`
A20				`@1 37-39`
A21				`@1 2001`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 7597 @5 354000095276990070`
A44				`@0 0000 @1 © 2001 INIST-CNRS. All rights reserved.`
A45				`@0 12 ref.`
A47	`01`	`1`		`@0 01-0325633`
A60				`@1 P @3 CC`
A61				`@0 A`
A64	`01`	`1`		`@0 British journal of haematology`
A66	`01`			`@0 GBR`
C01	`01`		`ENG`	@0 Plasma samples from replacement and volunteer blood donors in Kumasi, Ghana were pooled and tested using a duplex human immunodeficiency virus (HIV) and hepatitis C virus (HCV) RNA detection method. Individual plasmas constitutive of reactive pools were confirmed using reverse transcription-polymerase chain reaction. HIV and HCV infections were significantly higher in 1569 replacement donors than in 1169 volunteers; 2.4 and 1.7 versus 0.3 and 0.7% respectively (P < 0.01). Two duplex RNA-positive plasma pools contained a confirmed/seronegative HIV or HCV RNA individual plasma. The residual post-transfusion risk of HIV and HCV infection of blood collected from replacement blood donors ranged between 1:260 and 1:16 393 after screening for anti-HIV p24 antigen and anti-HCV, These data indicate that in high-prevalence HIV and HCV blood donor populations, a substantial residual post-transfusion risk of infection remains. This risk might be reduced by collecting blood in younger volunteer donors or by genomic screening.
C02	`01`	`X`		`@0 002B27D01`
C03	`01`	`X`	`FRE`	`@0 Transfusion @5 01`
C03	`01`	`X`	`ENG`	`@0 Transfusion @5 01`
C03	`01`	`X`	`SPA`	`@0 Transfusión @5 01`
C03	`02`	`X`	`FRE`	`@0 Sécurité transfusionnelle @5 02`
C03	`02`	`X`	`ENG`	`@0 Transfusion safety @5 02`
C03	`02`	`X`	`SPA`	`@0 Seguridad de la transfusión @5 02`
C03	`03`	`X`	`FRE`	`@0 Donneur sang @5 03`
C03	`03`	`X`	`ENG`	`@0 Blood donor @5 03`
C03	`03`	`X`	`SPA`	`@0 Donador sangre @5 03`
C03	`04`	`X`	`FRE`	`@0 Virus immunodéficience humaine @2 NW @5 04`
C03	`04`	`X`	`ENG`	`@0 Human immunodeficiency virus @2 NW @5 04`
C03	`04`	`X`	`SPA`	`@0 Human immunodeficiency virus @2 NW @5 04`
C03	`05`	`X`	`FRE`	`@0 Virus hépatite C @2 NW @5 05`
C03	`05`	`X`	`ENG`	`@0 Hepatitis C virus @2 NW @5 05`
C03	`05`	`X`	`SPA`	`@0 Hepatitis C virus @2 NW @5 05`
C03	`06`	`X`	`FRE`	`@0 Risque infectieux @5 06`
C03	`06`	`X`	`ENG`	`@0 Infectious risk @5 06`
C03	`06`	`X`	`SPA`	`@0 Riesgo infeccioso @5 06`
C03	`07`	`X`	`FRE`	`@0 Homme @5 18`
C03	`07`	`X`	`ENG`	`@0 Human @5 18`
C03	`07`	`X`	`SPA`	`@0 Hombre @5 18`
C07	`01`	`X`	`FRE`	`@0 Lentivirus @2 NW`
C07	`01`	`X`	`ENG`	`@0 Lentivirus @2 NW`
C07	`01`	`X`	`SPA`	`@0 Lentivirus @2 NW`
C07	`02`	`X`	`FRE`	`@0 Retroviridae @2 NW`
C07	`02`	`X`	`ENG`	`@0 Retroviridae @2 NW`
C07	`02`	`X`	`SPA`	`@0 Retroviridae @2 NW`
C07	`03`	`X`	`FRE`	`@0 Virus @2 NW`
C07	`03`	`X`	`ENG`	`@0 Virus @2 NW`
C07	`03`	`X`	`SPA`	`@0 Virus @2 NW`
C07	`04`	`X`	`FRE`	`@0 Hepacivirus @2 NW`
C07	`04`	`X`	`ENG`	`@0 Hepacivirus @2 NW`
C07	`04`	`X`	`SPA`	`@0 Hepacivirus @2 NW`
C07	`05`	`X`	`FRE`	`@0 Flaviviridae @2 NW`
C07	`05`	`X`	`ENG`	`@0 Flaviviridae @2 NW`
C07	`05`	`X`	`SPA`	`@0 Flaviviridae @2 NW`
N21				`@1 225`

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Pascal:01-0325633

Le document en format XML

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<author><name sortKey="Sarkodie, Francis" sort="Sarkodie, Francis" uniqKey="Sarkodie F" first="Francis" last="Sarkodie">Francis Sarkodie</name>
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<author><name sortKey="Allain, Jean Pierre" sort="Allain, Jean Pierre" uniqKey="Allain J" first="Jean-Pierre" last="Allain">Jean-Pierre Allain</name>
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	Le SIDA au Ghana (serveur d'exploration)
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Le SIDA au Ghana (serveur d'exploration)

Residual risk of transfusion in Ghana

Residual risk of transfusion in Ghana

Source :

Descripteurs français

English descriptors

Abstract

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