Suitability of a rapid immunochromatographic test for detection of antibodies to human immunodeficiency virus in Ghana, West Africa
Identifieur interne : 000132 ( PascalFrancis/Corpus ); précédent : 000131; suivant : 000133Suitability of a rapid immunochromatographic test for detection of antibodies to human immunodeficiency virus in Ghana, West Africa
Auteurs : S. Aidoo ; W. K. Ampofo ; J. A. M. Brandful ; S. V. Nuvor ; J. K. Ansah ; N. Nii-Trebi ; J. S. Barnor ; F. Apeagyei ; T. Sata ; D. Ofori-Adjei ; K. IshikawaSource :
- Journal of clinical microbiology [ 0095-1137 ] ; 2001.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
In West African countries such as Ghana, efficient human immunodeficiency virus (HIV) testing is a priority in the fight against AIDS. A new immunochromatographic rapid test, Determine HIV-1/2 (Abbott Diagnostics, North Chicago, Ill.), that detects antibodies against HIV type 1 (HIV-1) and/or HIV-2 was evaluated using Ghanaian blood samples. Two hundred four serum and/or plasma specimens were tested. HIV screening was done by a particle agglutination test and confirmed by a Western blot (WB) test as the "gold standard." The results revealed 125 HIV-seropositive AIDS patients, 75 HIV-seronegative healthy individuals, and 4 individuals for whom the HIV-1 result was indeterminate. The results obtained by the Determine HIV-1/2 assay and Diagnostic HIV SPOT (Genelabs), which is currently widely used in many districts in Ghana, were compared with those of the WB test, excluding the four HIV-1-indeterminate samples. The sensitivity of the Determine HIV-1/2 assay was 100%, compared with 98.0% for the HIV SPOT assay. The specificity was 100% for both tests. Determine HIV-1/2 is a single-step assay and was found to be rapid and easy to perform without any special equipment. It was highly sensitive and specific. The kit can be applied without electricity and water supplies, making it suitable for the detection of HIV antibodies especially in the rural areas of Ghana, West Africa.
Notice en format standard (ISO 2709)
Pour connaître la documentation sur le format Inist Standard.
pA |
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Format Inist (serveur)
NO : | PASCAL 02-0327136 INIST |
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ET : | Suitability of a rapid immunochromatographic test for detection of antibodies to human immunodeficiency virus in Ghana, West Africa |
AU : | AIDOO (S.); AMPOFO (W. K.); BRANDFUL (J. A. M.); NUVOR (S. V.); ANSAH (J. K.); NII-TREBI (N.); BARNOR (J. S.); APEAGYEI (F.); SATA (T.); OFORI-ADJEI (D.); ISHIKAWA (K.) |
AF : | Noguchi Memorial Institute for Medical Research, University of Ghana/Accra/Ghana (1 aut., 2 aut., 3 aut., 4 aut., 6 aut., 7 aut., 10 aut., 11 aut.); National Blood Transfusion Service, Ministry of Health/Korle-Bu/Ghana (5 aut.); Hygiene Wing, Military Hospital/Accra/Ghana (8 aut.); National Institute of Infectious Diseases/Tokyo/Japon (9 aut., 11 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | Journal of clinical microbiology; ISSN 0095-1137; Coden JCMIDW; Etats-Unis; Da. 2001; Vol. 39; No. 7; Pp. 2572-2575; Bibl. 18 ref. |
LA : | Anglais |
EA : | In West African countries such as Ghana, efficient human immunodeficiency virus (HIV) testing is a priority in the fight against AIDS. A new immunochromatographic rapid test, Determine HIV-1/2 (Abbott Diagnostics, North Chicago, Ill.), that detects antibodies against HIV type 1 (HIV-1) and/or HIV-2 was evaluated using Ghanaian blood samples. Two hundred four serum and/or plasma specimens were tested. HIV screening was done by a particle agglutination test and confirmed by a Western blot (WB) test as the "gold standard." The results revealed 125 HIV-seropositive AIDS patients, 75 HIV-seronegative healthy individuals, and 4 individuals for whom the HIV-1 result was indeterminate. The results obtained by the Determine HIV-1/2 assay and Diagnostic HIV SPOT (Genelabs), which is currently widely used in many districts in Ghana, were compared with those of the WB test, excluding the four HIV-1-indeterminate samples. The sensitivity of the Determine HIV-1/2 assay was 100%, compared with 98.0% for the HIV SPOT assay. The specificity was 100% for both tests. Determine HIV-1/2 is a single-step assay and was found to be rapid and easy to perform without any special equipment. It was highly sensitive and specific. The kit can be applied without electricity and water supplies, making it suitable for the detection of HIV antibodies especially in the rural areas of Ghana, West Africa. |
CC : | 002B05C03; 002B05C02D; 002A05 |
FD : | Homme; Virus immunodéficience humaine; Détection; Anticorps; Ghana; Afrique Ouest; Immunodéficit |
FG : | Lentivirus; Retroviridae; Virus; Afrique; Immunopathologie |
ED : | Human; Human immunodeficiency virus; Detection; Antibody; Ghana; West Africa; Immune deficiency |
EG : | Lentivirus; Retroviridae; Virus; Africa; Immunopathology |
SD : | Hombre; Human immunodeficiency virus; Detección; Anticuerpo; Ghana; Africa occidental; Inmunodeficiencia |
LO : | INIST-17088.354000096613080290 |
ID : | 02-0327136 |
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Pascal:02-0327136Le document en format XML
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<series><title level="j" type="main">Journal of clinical microbiology</title>
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<front><div type="abstract" xml:lang="en">In West African countries such as Ghana, efficient human immunodeficiency virus (HIV) testing is a priority in the fight against AIDS. A new immunochromatographic rapid test, Determine HIV-1/2 (Abbott Diagnostics, North Chicago, Ill.), that detects antibodies against HIV type 1 (HIV-1) and/or HIV-2 was evaluated using Ghanaian blood samples. Two hundred four serum and/or plasma specimens were tested. HIV screening was done by a particle agglutination test and confirmed by a Western blot (WB) test as the "gold standard." The results revealed 125 HIV-seropositive AIDS patients, 75 HIV-seronegative healthy individuals, and 4 individuals for whom the HIV-1 result was indeterminate. The results obtained by the Determine HIV-1/2 assay and Diagnostic HIV SPOT (Genelabs), which is currently widely used in many districts in Ghana, were compared with those of the WB test, excluding the four HIV-1-indeterminate samples. The sensitivity of the Determine HIV-1/2 assay was 100%, compared with 98.0% for the HIV SPOT assay. The specificity was 100% for both tests. Determine HIV-1/2 is a single-step assay and was found to be rapid and easy to perform without any special equipment. It was highly sensitive and specific. The kit can be applied without electricity and water supplies, making it suitable for the detection of HIV antibodies especially in the rural areas of Ghana, West Africa.</div>
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<fA14 i1="04"><s1>National Institute of Infectious Diseases</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>9 aut.</sZ>
<sZ>11 aut.</sZ>
</fA14>
<fA20><s1>2572-2575</s1>
</fA20>
<fA21><s1>2001</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>17088</s2>
<s5>354000096613080290</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2002 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>18 ref.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>02-0327136</s0>
</fA47>
<fA60><s1>P</s1>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>Journal of clinical microbiology</s0>
</fA64>
<fA66 i1="01"><s0>USA</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>In West African countries such as Ghana, efficient human immunodeficiency virus (HIV) testing is a priority in the fight against AIDS. A new immunochromatographic rapid test, Determine HIV-1/2 (Abbott Diagnostics, North Chicago, Ill.), that detects antibodies against HIV type 1 (HIV-1) and/or HIV-2 was evaluated using Ghanaian blood samples. Two hundred four serum and/or plasma specimens were tested. HIV screening was done by a particle agglutination test and confirmed by a Western blot (WB) test as the "gold standard." The results revealed 125 HIV-seropositive AIDS patients, 75 HIV-seronegative healthy individuals, and 4 individuals for whom the HIV-1 result was indeterminate. The results obtained by the Determine HIV-1/2 assay and Diagnostic HIV SPOT (Genelabs), which is currently widely used in many districts in Ghana, were compared with those of the WB test, excluding the four HIV-1-indeterminate samples. The sensitivity of the Determine HIV-1/2 assay was 100%, compared with 98.0% for the HIV SPOT assay. The specificity was 100% for both tests. Determine HIV-1/2 is a single-step assay and was found to be rapid and easy to perform without any special equipment. It was highly sensitive and specific. The kit can be applied without electricity and water supplies, making it suitable for the detection of HIV antibodies especially in the rural areas of Ghana, West Africa.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B05C03</s0>
</fC02>
<fC02 i1="02" i2="X"><s0>002B05C02D</s0>
</fC02>
<fC02 i1="03" i2="X"><s0>002A05</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Homme</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Human</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Hombre</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Virus immunodéficience humaine</s0>
<s2>NW</s2>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Human immunodeficiency virus</s0>
<s2>NW</s2>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Human immunodeficiency virus</s0>
<s2>NW</s2>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Détection</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Detection</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Detección</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Anticorps</s0>
<s5>06</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Antibody</s0>
<s5>06</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Anticuerpo</s0>
<s5>06</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Ghana</s0>
<s2>NG</s2>
<s5>07</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Ghana</s0>
<s2>NG</s2>
<s5>07</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Ghana</s0>
<s2>NG</s2>
<s5>07</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Afrique Ouest</s0>
<s2>NG</s2>
<s5>08</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>West Africa</s0>
<s2>NG</s2>
<s5>08</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Africa occidental</s0>
<s2>NG</s2>
<s5>08</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Immunodéficit</s0>
<s5>14</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Immune deficiency</s0>
<s5>14</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Inmunodeficiencia</s0>
<s5>14</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Lentivirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Lentivirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Lentivirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Retroviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Retroviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Retroviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Afrique</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Africa</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Africa</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Immunopathologie</s0>
<s5>20</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Immunopathology</s0>
<s5>20</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Inmunopatología</s0>
<s5>20</s5>
</fC07>
<fN21><s1>182</s1>
</fN21>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
<server><NO>PASCAL 02-0327136 INIST</NO>
<ET>Suitability of a rapid immunochromatographic test for detection of antibodies to human immunodeficiency virus in Ghana, West Africa</ET>
<AU>AIDOO (S.); AMPOFO (W. K.); BRANDFUL (J. A. M.); NUVOR (S. V.); ANSAH (J. K.); NII-TREBI (N.); BARNOR (J. S.); APEAGYEI (F.); SATA (T.); OFORI-ADJEI (D.); ISHIKAWA (K.)</AU>
<AF>Noguchi Memorial Institute for Medical Research, University of Ghana/Accra/Ghana (1 aut., 2 aut., 3 aut., 4 aut., 6 aut., 7 aut., 10 aut., 11 aut.); National Blood Transfusion Service, Ministry of Health/Korle-Bu/Ghana (5 aut.); Hygiene Wing, Military Hospital/Accra/Ghana (8 aut.); National Institute of Infectious Diseases/Tokyo/Japon (9 aut., 11 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Journal of clinical microbiology; ISSN 0095-1137; Coden JCMIDW; Etats-Unis; Da. 2001; Vol. 39; No. 7; Pp. 2572-2575; Bibl. 18 ref.</SO>
<LA>Anglais</LA>
<EA>In West African countries such as Ghana, efficient human immunodeficiency virus (HIV) testing is a priority in the fight against AIDS. A new immunochromatographic rapid test, Determine HIV-1/2 (Abbott Diagnostics, North Chicago, Ill.), that detects antibodies against HIV type 1 (HIV-1) and/or HIV-2 was evaluated using Ghanaian blood samples. Two hundred four serum and/or plasma specimens were tested. HIV screening was done by a particle agglutination test and confirmed by a Western blot (WB) test as the "gold standard." The results revealed 125 HIV-seropositive AIDS patients, 75 HIV-seronegative healthy individuals, and 4 individuals for whom the HIV-1 result was indeterminate. The results obtained by the Determine HIV-1/2 assay and Diagnostic HIV SPOT (Genelabs), which is currently widely used in many districts in Ghana, were compared with those of the WB test, excluding the four HIV-1-indeterminate samples. The sensitivity of the Determine HIV-1/2 assay was 100%, compared with 98.0% for the HIV SPOT assay. The specificity was 100% for both tests. Determine HIV-1/2 is a single-step assay and was found to be rapid and easy to perform without any special equipment. It was highly sensitive and specific. The kit can be applied without electricity and water supplies, making it suitable for the detection of HIV antibodies especially in the rural areas of Ghana, West Africa.</EA>
<CC>002B05C03; 002B05C02D; 002A05</CC>
<FD>Homme; Virus immunodéficience humaine; Détection; Anticorps; Ghana; Afrique Ouest; Immunodéficit</FD>
<FG>Lentivirus; Retroviridae; Virus; Afrique; Immunopathologie</FG>
<ED>Human; Human immunodeficiency virus; Detection; Antibody; Ghana; West Africa; Immune deficiency</ED>
<EG>Lentivirus; Retroviridae; Virus; Africa; Immunopathology</EG>
<SD>Hombre; Human immunodeficiency virus; Detección; Anticuerpo; Ghana; Africa occidental; Inmunodeficiencia</SD>
<LO>INIST-17088.354000096613080290</LO>
<ID>02-0327136</ID>
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