Le SIDA au Ghana (serveur d'exploration)

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The effect of school attendance and school dropout on incident HIV and HSV-2 among young women in rural South Africa enrolled in HPTN 068.

Identifieur interne : 000B61 ( Ncbi/Merge ); précédent : 000B60; suivant : 000B62

The effect of school attendance and school dropout on incident HIV and HSV-2 among young women in rural South Africa enrolled in HPTN 068.

Auteurs : Marie C D. Stoner [Afrique du Sud] ; Audrey Pettifor ; Jessie K. Edwards ; Allison E. Aiello ; Carolyn T. Halpern ; Aimée Julien ; Amanda Selin ; Rhian Twine ; James P. Hughes ; Jing Wang ; Yaw Agyei ; F Xavier Gomez-Olive ; Ryan G. Wagner ; Catherine Macphail ; Kathleen Kahn

Source :

RBID : pubmed:28692544

Abstract

To estimate the association between school attendance, school dropout, and risk of incident HIV and herpes simplex virus type 2 (HSV-2) infection among young women.

DOI: 10.1097/QAD.0000000000001584
PubMed: 28692544

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pubmed:28692544

Le document en format XML

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<nlm:affiliation>aDepartment of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, USA bMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), Faculty of Health Sciences, School of Public Health, University of the Witwatersrand, Johannesburg, South Africa cDepartment of Maternal and Child Health, University of North Carolina, Chapel Hill, North Carolina, USA dEpidemiology and Global Health Unit, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden eDepartment of Biostatistics, University of Washington fFred Hutchinson Cancer Research Center, Seattle, Washington gDepartment of Pathology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA hINDEPTH Network, Accra, Ghana, West Africa iSchool of Health and Society, University of Wollongong, New South Wales, Australia jWits Reproductive Health and HIV Research Institute, University of the Witwatersrand, Johannesburg, South Africa.</nlm:affiliation>
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<wicri:regionArea>aDepartment of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, USA bMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), Faculty of Health Sciences, School of Public Health, University of the Witwatersrand, Johannesburg, South Africa cDepartment of Maternal and Child Health, University of North Carolina, Chapel Hill, North Carolina, USA dEpidemiology and Global Health Unit, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden eDepartment of Biostatistics, University of Washington fFred Hutchinson Cancer Research Center, Seattle, Washington gDepartment of Pathology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA hINDEPTH Network, Accra, Ghana, West Africa iSchool of Health and Society, University of Wollongong, New South Wales, Australia jWits Reproductive Health and HIV Research Institute, University of the Witwatersrand, Johannesburg</wicri:regionArea>
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<div type="abstract" xml:lang="en">To estimate the association between school attendance, school dropout, and risk of incident HIV and herpes simplex virus type 2 (HSV-2) infection among young women.</div>
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<ArticleTitle>The effect of school attendance and school dropout on incident HIV and HSV-2 among young women in rural South Africa enrolled in HPTN 068.</ArticleTitle>
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<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To estimate the association between school attendance, school dropout, and risk of incident HIV and herpes simplex virus type 2 (HSV-2) infection among young women.</AbstractText>
<AbstractText Label="DESIGN" NlmCategory="METHODS">We used longitudinal data from a randomized controlled trial in rural Mpumalanga province, South Africa, to assess the association between school days attended, school dropout, and incident HIV and HSV-2 in young women aged 13-23 years.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">We examined inverse probability of exposure weighted survival curves and used them to calculate 1.5, 2.5, and 3.5-year risk differences and risk ratios for the effect of school attendance on incident HIV and HSV-2. A marginal structural Cox model was used to estimate hazard ratios for the effect of school attendance and school dropout on incident infection.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Risk of infection increased over time as young women aged, and was higher in young women with low school attendance (<80% school days) compared with high (≥80% school days). Young women with low attendance were more likely to acquire HIV [hazard ratio (HR): 2.97; 95% confidence interval (CI): 1.62, 5.45] and HSV-2 (HR: 2.47; 95% CI: 1.46, 4.17) over the follow-up period than young women with high attendance. Similarly, young women who dropped out of school had a higher weighted hazard of both HIV (HR 3.25 95% CI: 1.67, 6.32) and HSV-2 (HR 2.70; 95% CI 1.59, 4.59).</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Young women who attend more school days and stay in school have a lower risk of incident HIV and HSV-2 infection. Interventions to increase frequency of school attendance and prevent dropout should be promoted to reduce risk of infection.</AbstractText>
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<ForeName>Marie C D</ForeName>
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<Affiliation>aDepartment of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, USA bMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), Faculty of Health Sciences, School of Public Health, University of the Witwatersrand, Johannesburg, South Africa cDepartment of Maternal and Child Health, University of North Carolina, Chapel Hill, North Carolina, USA dEpidemiology and Global Health Unit, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden eDepartment of Biostatistics, University of Washington fFred Hutchinson Cancer Research Center, Seattle, Washington gDepartment of Pathology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA hINDEPTH Network, Accra, Ghana, West Africa iSchool of Health and Society, University of Wollongong, New South Wales, Australia jWits Reproductive Health and HIV Research Institute, University of the Witwatersrand, Johannesburg, South Africa.</Affiliation>
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<RefSource>J Adolesc Health. 2006 Oct;39(4):596.e11-8</RefSource>
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<CommentsCorrections RefType="Cites">
<RefSource>AIDS. 2007 Nov;21 Suppl 7:S29-38</RefSource>
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<CommentsCorrections RefType="Cites">
<RefSource>AIDS. 2008 Dec;22 Suppl 4:S41-56</RefSource>
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<CommentsCorrections RefType="Cites">
<RefSource>AIDS Behav. 2006 Sep;10(5):541-52</RefSource>
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<RefSource>Epidemiology. 2000 Sep;11(5):561-70</RefSource>
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