Le SIDA au Ghana (serveur d'exploration)

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Genotypic characterisation of human papillomavirus infections among persons living with HIV infection; a case-control study in Kumasi, Ghana.

Identifieur interne : 000907 ( Ncbi/Merge ); précédent : 000906; suivant : 000908

Genotypic characterisation of human papillomavirus infections among persons living with HIV infection; a case-control study in Kumasi, Ghana.

Auteurs : Denis Dekugmen Yar [Ghana] ; Samson Pandam Salifu [Ghana] ; Samuel Nkansah Darko [Ghana] ; Augustina Angelina Annan [Ghana] ; Akosua Adumea Gyimah [Ghana] ; Kwame Ohene Buabeng [Ghana] ; Ellis Owusu-Dabo [Ghana]

Source :

RBID : pubmed:26598430

Descripteurs français

English descriptors

Abstract

The objective of this study is to describe the burden of human papillomavirus (HPV) infection among women living with HIV and non-infected women in Ghana.

DOI: 10.1111/tmi.12645
PubMed: 26598430

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pubmed:26598430

Le document en format XML

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<div type="abstract" xml:lang="en">The objective of this study is to describe the burden of human papillomavirus (HPV) infection among women living with HIV and non-infected women in Ghana.</div>
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<Day>02</Day>
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<Month>06</Month>
<Day>09</Day>
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<Title>Tropical medicine & international health : TM & IH</Title>
<ISOAbbreviation>Trop. Med. Int. Health</ISOAbbreviation>
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<ArticleTitle>Genotypic characterisation of human papillomavirus infections among persons living with HIV infection; a case-control study in Kumasi, Ghana.</ArticleTitle>
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<AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">The objective of this study is to describe the burden of human papillomavirus (HPV) infection among women living with HIV and non-infected women in Ghana.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">A case-control study was conducted involving 107 women living with HIV aged between 18 and 59 years (cases) and 100 non-HIV-infected apparently healthy women (controls) who were recruited from the Kumasi South Hospital, from July to December, 2014. Cervicovaginal swabs were taken from study participants to characterise 28 high- and low-risk HPV genotypes using a multiplex real-time PCR.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The overall mean age for the participants was 40.10 ± 9.76 years. The prevalence of high-risk (hr)-HPV genotypes was significantly higher among the cases than the controls (77.4% vs. 41.6%, P < 0.0001). Overall, HPV 58 and 54 were the most predominant high-risk (18.8%) and low-risk (15.0%) genotypes detected. The two most common hr-HPV genotype isolates were 58 (18.8%) and 35 (15.9%) with 58 being the most prevalent among age group 35-44 years compared with hr-HPV 16, 18, 35 and 45, found predominantly among 18-34 age group.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Significant variations exist in HPV genotypes among HIV-infected and uninfected women.</AbstractText>
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<Affiliation>School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.</Affiliation>
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<name sortKey="Yar, Denis Dekugmen" sort="Yar, Denis Dekugmen" uniqKey="Yar D" first="Denis Dekugmen" last="Yar">Denis Dekugmen Yar</name>
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<name sortKey="Annan, Augustina Angelina" sort="Annan, Augustina Angelina" uniqKey="Annan A" first="Augustina Angelina" last="Annan">Augustina Angelina Annan</name>
<name sortKey="Buabeng, Kwame Ohene" sort="Buabeng, Kwame Ohene" uniqKey="Buabeng K" first="Kwame Ohene" last="Buabeng">Kwame Ohene Buabeng</name>
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<name sortKey="Gyimah, Akosua Adumea" sort="Gyimah, Akosua Adumea" uniqKey="Gyimah A" first="Akosua Adumea" last="Gyimah">Akosua Adumea Gyimah</name>
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