Pre-donation screening of blood for transfusion transmissible infections: the gains and the pains - experience at a resource limited blood bank.
Identifieur interne : 000763 ( Ncbi/Merge ); précédent : 000762; suivant : 000764Pre-donation screening of blood for transfusion transmissible infections: the gains and the pains - experience at a resource limited blood bank.
Auteurs : A O Shittu ; H O Olawumi ; J O AdewuyiSource :
- Ghana medical journal [ 0016-9560 ] ; 2014.
Descripteurs français
- KwdFr :
- Analyse coût-bénéfice, Banques de sang (), Banques de sang (économie), Donneurs de sang, Dépistage systématique (), Dépistage systématique (économie), Humains, Hépatite B (), Hépatite B (transmission), Hépatite C (), Hépatite C (transmission), Infections à VIH (), Infections à VIH (transmission), Nigeria, Pathogènes transmissibles par le sang, Pays en voie de développement, Sécurité transfusionnelle (), Sécurité transfusionnelle (économie), Transfusion sanguine (effets indésirables), Études rétrospectives.
- MESH :
- effets indésirables : Transfusion sanguine.
- économie : Banques de sang, Dépistage systématique, Hépatite B, Hépatite C, Infections à VIH, Sécurité transfusionnelle.
- Analyse coût-bénéfice, Banques de sang, Donneurs de sang, Dépistage systématique, Humains, Hépatite B, Hépatite C, Infections à VIH, Nigeria, Pathogènes transmissibles par le sang, Pays en voie de développement, Sécurité transfusionnelle, Études rétrospectives.
- Wicri :
- geographic : Nigeria.
English descriptors
- KwdEn :
- Blood Banks (economics), Blood Banks (methods), Blood Donors, Blood Safety (economics), Blood Safety (methods), Blood Transfusion (adverse effects), Blood-Borne Pathogens, Cost-Benefit Analysis, Developing Countries, HIV Infections (prevention & control), HIV Infections (transmission), Hepatitis B (prevention & control), Hepatitis B (transmission), Hepatitis C (prevention & control), Hepatitis C (transmission), Humans, Mass Screening (economics), Mass Screening (methods), Nigeria, Retrospective Studies.
- MESH :
- geographic : Nigeria.
- adverse effects : Blood Transfusion.
- economics : Blood Banks, Blood Safety, Mass Screening.
- methods : Blood Banks, Blood Safety, Mass Screening.
- prevention & control : HIV Infections, Hepatitis B, Hepatitis C.
- transmission : HIV Infections, Hepatitis B, Hepatitis C.
- Blood Donors, Blood-Borne Pathogens, Cost-Benefit Analysis, Developing Countries, Humans, Retrospective Studies.
Abstract
To determine whether or not pre-donation testing of blood donors affords substantial cost savings without compromise to blood transfusion safety. Pre-donation testing of blood donors for Transfusion Transmissible Infections (TTIs) is done in most developing countries because substantial cost savings are made from resources, materials and man-hours which would have been spent to procure infected blood units. Simple rapid test kits used in pre-donation testing is not as sensitive as the Enzyme Linked Immuno-sorbent Assay (ELISA) method used in post-donation screening in a quality assured manner.
PubMed: 25709126
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pubmed:25709126Le document en format XML
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Pre-donation testing of blood donors for Transfusion Transmissible Infections (TTIs) is done in most developing countries because substantial cost savings are made from resources, materials and man-hours which would have been spent to procure infected blood units. Simple rapid test kits used in pre-donation testing is not as sensitive as the Enzyme Linked Immuno-sorbent Assay (ELISA) method used in post-donation screening in a quality assured manner.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25709126</PMID><DateCreated><Year>2015</Year><Month>02</Month><Day>24</Day></DateCreated><DateCompleted><Year>2015</Year><Month>10</Month><Day>07</Day></DateCompleted><DateRevised><Year>2015</Year><Month>10</Month><Day>28</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0016-9560</ISSN><JournalIssue CitedMedium="Internet"><Volume>48</Volume><Issue>3</Issue><PubDate><Year>2014</Year><Month>Sep</Month></PubDate></JournalIssue><Title>Ghana medical journal</Title><ISOAbbreviation>Ghana Med J</ISOAbbreviation></Journal><ArticleTitle>Pre-donation screening of blood for transfusion transmissible infections: the gains and the pains - experience at a resource limited blood bank.</ArticleTitle><Pagination><MedlinePgn>158-62</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To determine whether or not pre-donation testing of blood donors affords substantial cost savings without compromise to blood transfusion safety. Pre-donation testing of blood donors for Transfusion Transmissible Infections (TTIs) is done in most developing countries because substantial cost savings are made from resources, materials and man-hours which would have been spent to procure infected blood units. Simple rapid test kits used in pre-donation testing is not as sensitive as the Enzyme Linked Immuno-sorbent Assay (ELISA) method used in post-donation screening in a quality assured manner.</AbstractText><AbstractText Label="DESIGN" NlmCategory="METHODS">It is a retrospective study where records of pre- and post-donation tests done in donor clinic of University of Ilorin Teaching Hospital, between January and December 2010 were retrieved. All processes and inputs were evaluated and costs calculated for pre-donation testing by simple rapid techniques and post donation screening by ELISA.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">5000 prospective donors were tested in the study period. The cost of single rapid Pre-donation testing was less than that of single ELISA Post-donation screen. The cost of double rapid Pre-donation and Post donation ELISA screen exceeded the cost of single post donation ELISA screen. Substantial cost savings were made when single rapid Pre-donation testing is relied on. More blood units were found reactive for the TTIs with the more expensive Post-donation ELISA.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Pre-donation testing of blood donors was not cost effective. Although, there is an apparent savings if pre-donation testing is not followed by post-donation ELISA testing, it is done at a compromise to blood transfusion safety.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Shittu</LastName><ForeName>A O</ForeName><Initials>AO</Initials><AffiliationInfo><Affiliation>Department of Haematology and Blood Transfusion, University of Ilorin.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Olawumi</LastName><ForeName>H O</ForeName><Initials>HO</Initials><AffiliationInfo><Affiliation>Department of Haematology and Blood Transfusion, University of Ilorin.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Adewuyi</LastName><ForeName>J O</ForeName><Initials>JO</Initials><AffiliationInfo><Affiliation>Department of Haematology and Blood Transfusion, University of Ilorin.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Ghana</Country><MedlineTA>Ghana Med J</MedlineTA><NlmUniqueID>0073210</NlmUniqueID><ISSNLinking>0016-9560</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>N Engl J Med. 1996 Jun 27;334(26):1685-90</RefSource><PMID Version="1">8637512</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Transfus Med Rev. 1997 Jul;11(3):155-72</RefSource><PMID Version="1">9243769</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Virol J. 2011;8:105</RefSource><PMID Version="1">21385397</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Intern Med J. 2005 Oct;35(10):592-8</RefSource><PMID Version="1">16207258</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Transfusion. 2005 Feb;45(2):133-40</RefSource><PMID Version="1">15660820</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D001771" MajorTopicYN="N">Blood Banks</DescriptorName><QualifierName UI="Q000191" MajorTopicYN="Y">economics</QualifierName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001782" MajorTopicYN="Y">Blood Donors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058731" MajorTopicYN="N">Blood Safety</DescriptorName><QualifierName UI="Q000191" MajorTopicYN="Y">economics</QualifierName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001803" MajorTopicYN="N">Blood Transfusion</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017848" MajorTopicYN="N">Blood-Borne Pathogens</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003362" MajorTopicYN="N">Cost-Benefit Analysis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003906" MajorTopicYN="Y">Developing Countries</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015658" MajorTopicYN="N">HIV Infections</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName><QualifierName UI="Q000635" MajorTopicYN="N">transmission</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006509" MajorTopicYN="N">Hepatitis B</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName><QualifierName UI="Q000635" MajorTopicYN="N">transmission</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006526" MajorTopicYN="N">Hepatitis C</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName><QualifierName UI="Q000635" MajorTopicYN="N">transmission</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008403" MajorTopicYN="N">Mass Screening</DescriptorName><QualifierName UI="Q000191" MajorTopicYN="Y">economics</QualifierName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009549" MajorTopicYN="N" Type="Geographic">Nigeria</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading></MeshHeadingList><OtherID Source="NLM">PMC4335446</OtherID><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">TTIs screening</Keyword><Keyword MajorTopicYN="N">post-donation</Keyword><Keyword MajorTopicYN="N">pre-donation</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>2</Month><Day>25</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>2</Month><Day>25</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>10</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">25709126</ArticleId><ArticleId IdType="pmc">PMC4335446</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list></list><tree><noCountry><name sortKey="Adewuyi, J O" sort="Adewuyi, J O" uniqKey="Adewuyi J" first="J O" last="Adewuyi">J O Adewuyi</name><name sortKey="Olawumi, H O" sort="Olawumi, H O" uniqKey="Olawumi H" first="H O" last="Olawumi">H O Olawumi</name><name sortKey="Shittu, A O" sort="Shittu, A O" uniqKey="Shittu A" first="A O" last="Shittu">A O Shittu</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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