Response to antiretroviral therapy in occult hepatitis B and HIV co-infection in West Africa.
Identifieur interne : 000507 ( Ncbi/Merge ); précédent : 000506; suivant : 000508Response to antiretroviral therapy in occult hepatitis B and HIV co-infection in West Africa.
Auteurs : David Chadwick [Royaume-Uni] ; Alastair Stanley ; Stephen Sarfo ; Lambert Appiah ; Michael Ankcorn ; Geraldine Foster ; Uli Schwab ; Richard Phillips ; Anna M. GerettiSource :
- AIDS (London, England) [ 1473-5571 ] ; 2013.
Descripteurs français
- KwdFr :
- Agents antiVIH (usage thérapeutique), Antigènes de surface du virus de l'hépatite B (sang), Charge virale (), Co-infection, Femelle, Ghana (épidémiologie), Humains, Hépatite B (immunologie), Hépatite B (traitement médicamenteux), Hépatite B (épidémiologie), Indice de masse corporelle, Infections à VIH (immunologie), Infections à VIH (traitement médicamenteux), Infections à VIH (épidémiologie), Inhibiteurs de la transcriptase inverse (usage thérapeutique), Lamivudine (usage thérapeutique), Mâle, Numération des lymphocytes CD4, Prévalence, Résultat thérapeutique, Évolution de la maladie.
- MESH :
- immunologie : Hépatite B, Infections à VIH.
- sang : Antigènes de surface du virus de l'hépatite B.
- traitement médicamenteux : Hépatite B, Infections à VIH.
- usage thérapeutique : Agents antiVIH, Inhibiteurs de la transcriptase inverse, Lamivudine.
- épidémiologie : Ghana, Hépatite B, Infections à VIH.
- Charge virale, Co-infection, Femelle, Humains, Indice de masse corporelle, Mâle, Numération des lymphocytes CD4, Prévalence, Résultat thérapeutique, Évolution de la maladie.
- Wicri :
- geographic : Ghana.
English descriptors
- KwdEn :
- Anti-HIV Agents (therapeutic use), Body Mass Index, CD4 Lymphocyte Count, Coinfection, Disease Progression, Female, Ghana (epidemiology), HIV Infections (drug therapy), HIV Infections (epidemiology), HIV Infections (immunology), Hepatitis B (drug therapy), Hepatitis B (epidemiology), Hepatitis B (immunology), Hepatitis B Surface Antigens (blood), Humans, Lamivudine (therapeutic use), Male, Prevalence, Reverse Transcriptase Inhibitors (therapeutic use), Treatment Outcome, Viral Load (drug effects).
- MESH :
- chemical , blood : Hepatitis B Surface Antigens.
- chemical , therapeutic use : Anti-HIV Agents, Lamivudine, Reverse Transcriptase Inhibitors.
- geographic , epidemiology : Ghana.
- drug effects : Viral Load.
- drug therapy : HIV Infections, Hepatitis B.
- epidemiology : HIV Infections, Hepatitis B.
- immunology : HIV Infections, Hepatitis B.
- Body Mass Index, CD4 Lymphocyte Count, Coinfection, Disease Progression, Female, Humans, Male, Prevalence, Treatment Outcome.
Abstract
This study evaluated the outcome of first-line antiretroviral therapy among 35 Ghanaians with occult HBV/HIV co-infection, comparing them over 2 years to 120 patients with HBsAg+ HBV/HIV co-infection and 230 patients without HBV co-infection. Increases in CD4 cell count and BMI were similar, whereas elevations of hepatic transaminases were more frequent in both the occult HBV and HBsAg+ patients. Occult HBV/HIV co-infection appears not to impact adversely on response to antiretroviral therapy in Ghana.
DOI: 10.1097/QAD.0b013e3283589879
PubMed: 22874516
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000256
- to stream PubMed, to step Curation: 000256
- to stream PubMed, to step Checkpoint: 000256
Links to Exploration step
pubmed:22874516Le document en format XML
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<front><div type="abstract" xml:lang="en">This study evaluated the outcome of first-line antiretroviral therapy among 35 Ghanaians with occult HBV/HIV co-infection, comparing them over 2 years to 120 patients with HBsAg+ HBV/HIV co-infection and 230 patients without HBV co-infection. Increases in CD4 cell count and BMI were similar, whereas elevations of hepatic transaminases were more frequent in both the occult HBV and HBsAg+ patients. Occult HBV/HIV co-infection appears not to impact adversely on response to antiretroviral therapy in Ghana.</div>
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