Determination of beta-defensin genomic copy number in different populations: a comparison of three methods.
Identifieur interne : 000412 ( Ncbi/Curation ); précédent : 000411; suivant : 000413Determination of beta-defensin genomic copy number in different populations: a comparison of three methods.
Auteurs : Peder Fode [Danemark] ; Cathrine Jespersgaard ; Robert J. Hardwick ; Helen Bogle ; Michael Theisen ; Daniel Dodoo ; Martin Lenicek ; Libor Vitek ; Ana Vieira ; Joao Freitas ; Paal Skytt Andersen ; Edward J. HolloxSource :
- PloS one [ 1932-6203 ] ; 2011.
Descripteurs français
- KwdFr :
- Cartographie chromosomique (), Danemark, Données de séquences moléculaires, Dosage génique, Ghana, Génome humain (génétique), Génétique des populations (), Humains, Population, Portugal, Prédisposition génétique à une maladie, Royaume-Uni, République tchèque, Séquence nucléotidique, bêta-Défensines (génétique), Études de cohortes.
- MESH :
- génétique : Génome humain, bêta-Défensines.
- Cartographie chromosomique, Danemark, Données de séquences moléculaires, Dosage génique, Ghana, Génétique des populations, Humains, Population, Portugal, Prédisposition génétique à une maladie, Royaume-Uni, République tchèque, Séquence nucléotidique, Études de cohortes.
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : beta-Defensins.
- genetics : Genome, Human.
- methods : Chromosome Mapping, Genetics, Population.
- Base Sequence, Cohort Studies, Czech Republic, Denmark, Gene Dosage, Genetic Predisposition to Disease, Ghana, Humans, Molecular Sequence Data, Population, Portugal, United Kingdom.
Abstract
There have been conflicting reports in the literature on association of gene copy number with disease, including CCL3L1 and HIV susceptibility, and β-defensins and Crohn's disease. Quantification of precise gene copy numbers is important in order to define any association of gene copy number with disease. At present, real-time quantitative PCR (QPCR) is the most commonly used method to determine gene copy number, however the Paralogue Ratio Test (PRT) is being used in more and more laboratories.
DOI: 10.1371/journal.pone.0016768
PubMed: 21364933
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000693
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :000693
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000693
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :000412
Links to Exploration step
pubmed:21364933Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Determination of beta-defensin genomic copy number in different populations: a comparison of three methods.</title>
<author><name sortKey="Fode, Peder" sort="Fode, Peder" uniqKey="Fode P" first="Peder" last="Fode">Peder Fode</name>
<affiliation wicri:level="3"><nlm:affiliation>Department for Microbiological Surveillance and Research, Statens Serum Institut, Copenhagen, Denmark.</nlm:affiliation>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Department for Microbiological Surveillance and Research, Statens Serum Institut, Copenhagen</wicri:regionArea>
<placeName><settlement type="city">Copenhague</settlement>
<region type="région" nuts="2">Hovedstaden</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jespersgaard, Cathrine" sort="Jespersgaard, Cathrine" uniqKey="Jespersgaard C" first="Cathrine" last="Jespersgaard">Cathrine Jespersgaard</name>
</author>
<author><name sortKey="Hardwick, Robert J" sort="Hardwick, Robert J" uniqKey="Hardwick R" first="Robert J" last="Hardwick">Robert J. Hardwick</name>
</author>
<author><name sortKey="Bogle, Helen" sort="Bogle, Helen" uniqKey="Bogle H" first="Helen" last="Bogle">Helen Bogle</name>
</author>
<author><name sortKey="Theisen, Michael" sort="Theisen, Michael" uniqKey="Theisen M" first="Michael" last="Theisen">Michael Theisen</name>
</author>
<author><name sortKey="Dodoo, Daniel" sort="Dodoo, Daniel" uniqKey="Dodoo D" first="Daniel" last="Dodoo">Daniel Dodoo</name>
</author>
<author><name sortKey="Lenicek, Martin" sort="Lenicek, Martin" uniqKey="Lenicek M" first="Martin" last="Lenicek">Martin Lenicek</name>
</author>
<author><name sortKey="Vitek, Libor" sort="Vitek, Libor" uniqKey="Vitek L" first="Libor" last="Vitek">Libor Vitek</name>
</author>
<author><name sortKey="Vieira, Ana" sort="Vieira, Ana" uniqKey="Vieira A" first="Ana" last="Vieira">Ana Vieira</name>
</author>
<author><name sortKey="Freitas, Joao" sort="Freitas, Joao" uniqKey="Freitas J" first="Joao" last="Freitas">Joao Freitas</name>
</author>
<author><name sortKey="Andersen, Paal Skytt" sort="Andersen, Paal Skytt" uniqKey="Andersen P" first="Paal Skytt" last="Andersen">Paal Skytt Andersen</name>
</author>
<author><name sortKey="Hollox, Edward J" sort="Hollox, Edward J" uniqKey="Hollox E" first="Edward J" last="Hollox">Edward J. Hollox</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2011">2011</date>
<idno type="RBID">pubmed:21364933</idno>
<idno type="pmid">21364933</idno>
<idno type="doi">10.1371/journal.pone.0016768</idno>
<idno type="wicri:Area/PubMed/Corpus">000693</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000693</idno>
<idno type="wicri:Area/PubMed/Curation">000693</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000693</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000693</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000693</idno>
<idno type="wicri:Area/Ncbi/Merge">000412</idno>
<idno type="wicri:Area/Ncbi/Curation">000412</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Determination of beta-defensin genomic copy number in different populations: a comparison of three methods.</title>
<author><name sortKey="Fode, Peder" sort="Fode, Peder" uniqKey="Fode P" first="Peder" last="Fode">Peder Fode</name>
<affiliation wicri:level="3"><nlm:affiliation>Department for Microbiological Surveillance and Research, Statens Serum Institut, Copenhagen, Denmark.</nlm:affiliation>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Department for Microbiological Surveillance and Research, Statens Serum Institut, Copenhagen</wicri:regionArea>
<placeName><settlement type="city">Copenhague</settlement>
<region type="région" nuts="2">Hovedstaden</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jespersgaard, Cathrine" sort="Jespersgaard, Cathrine" uniqKey="Jespersgaard C" first="Cathrine" last="Jespersgaard">Cathrine Jespersgaard</name>
</author>
<author><name sortKey="Hardwick, Robert J" sort="Hardwick, Robert J" uniqKey="Hardwick R" first="Robert J" last="Hardwick">Robert J. Hardwick</name>
</author>
<author><name sortKey="Bogle, Helen" sort="Bogle, Helen" uniqKey="Bogle H" first="Helen" last="Bogle">Helen Bogle</name>
</author>
<author><name sortKey="Theisen, Michael" sort="Theisen, Michael" uniqKey="Theisen M" first="Michael" last="Theisen">Michael Theisen</name>
</author>
<author><name sortKey="Dodoo, Daniel" sort="Dodoo, Daniel" uniqKey="Dodoo D" first="Daniel" last="Dodoo">Daniel Dodoo</name>
</author>
<author><name sortKey="Lenicek, Martin" sort="Lenicek, Martin" uniqKey="Lenicek M" first="Martin" last="Lenicek">Martin Lenicek</name>
</author>
<author><name sortKey="Vitek, Libor" sort="Vitek, Libor" uniqKey="Vitek L" first="Libor" last="Vitek">Libor Vitek</name>
</author>
<author><name sortKey="Vieira, Ana" sort="Vieira, Ana" uniqKey="Vieira A" first="Ana" last="Vieira">Ana Vieira</name>
</author>
<author><name sortKey="Freitas, Joao" sort="Freitas, Joao" uniqKey="Freitas J" first="Joao" last="Freitas">Joao Freitas</name>
</author>
<author><name sortKey="Andersen, Paal Skytt" sort="Andersen, Paal Skytt" uniqKey="Andersen P" first="Paal Skytt" last="Andersen">Paal Skytt Andersen</name>
</author>
<author><name sortKey="Hollox, Edward J" sort="Hollox, Edward J" uniqKey="Hollox E" first="Edward J" last="Hollox">Edward J. Hollox</name>
</author>
</analytic>
<series><title level="j">PloS one</title>
<idno type="eISSN">1932-6203</idno>
<imprint><date when="2011" type="published">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Base Sequence</term>
<term>Chromosome Mapping (methods)</term>
<term>Cohort Studies</term>
<term>Czech Republic</term>
<term>Denmark</term>
<term>Gene Dosage</term>
<term>Genetic Predisposition to Disease</term>
<term>Genetics, Population (methods)</term>
<term>Genome, Human (genetics)</term>
<term>Ghana</term>
<term>Humans</term>
<term>Molecular Sequence Data</term>
<term>Population</term>
<term>Portugal</term>
<term>United Kingdom</term>
<term>beta-Defensins (genetics)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Cartographie chromosomique ()</term>
<term>Danemark</term>
<term>Données de séquences moléculaires</term>
<term>Dosage génique</term>
<term>Ghana</term>
<term>Génome humain (génétique)</term>
<term>Génétique des populations ()</term>
<term>Humains</term>
<term>Population</term>
<term>Portugal</term>
<term>Prédisposition génétique à une maladie</term>
<term>Royaume-Uni</term>
<term>République tchèque</term>
<term>Séquence nucléotidique</term>
<term>bêta-Défensines (génétique)</term>
<term>Études de cohortes</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>beta-Defensins</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Genome, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Génome humain</term>
<term>bêta-Défensines</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Chromosome Mapping</term>
<term>Genetics, Population</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Base Sequence</term>
<term>Cohort Studies</term>
<term>Czech Republic</term>
<term>Denmark</term>
<term>Gene Dosage</term>
<term>Genetic Predisposition to Disease</term>
<term>Ghana</term>
<term>Humans</term>
<term>Molecular Sequence Data</term>
<term>Population</term>
<term>Portugal</term>
<term>United Kingdom</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Cartographie chromosomique</term>
<term>Danemark</term>
<term>Données de séquences moléculaires</term>
<term>Dosage génique</term>
<term>Ghana</term>
<term>Génétique des populations</term>
<term>Humains</term>
<term>Population</term>
<term>Portugal</term>
<term>Prédisposition génétique à une maladie</term>
<term>Royaume-Uni</term>
<term>République tchèque</term>
<term>Séquence nucléotidique</term>
<term>Études de cohortes</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">There have been conflicting reports in the literature on association of gene copy number with disease, including CCL3L1 and HIV susceptibility, and β-defensins and Crohn's disease. Quantification of precise gene copy numbers is important in order to define any association of gene copy number with disease. At present, real-time quantitative PCR (QPCR) is the most commonly used method to determine gene copy number, however the Paralogue Ratio Test (PRT) is being used in more and more laboratories.</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/SidaGhanaV1/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000412 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 000412 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= SidaGhanaV1 |flux= Ncbi |étape= Curation |type= RBID |clé= pubmed:21364933 |texte= Determination of beta-defensin genomic copy number in different populations: a comparison of three methods. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:21364933" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \ | NlmPubMed2Wicri -a SidaGhanaV1
This area was generated with Dilib version V0.6.31. |