Le SIDA au Ghana (serveur d'exploration)

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Isolation and characterization of a highly divergent HIV-2[GH-2] : generation of an infectious molecular clone and functional analysis of its rev-responsive element in response to primate retrovirus tansactivators (rev and rex)

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Isolation and characterization of a highly divergent HIV-2[GH-2] : generation of an infectious molecular clone and functional analysis of its rev-responsive element in response to primate retrovirus tansactivators (rev and rex)

Auteurs : M. Kawamura [Japon] ; J. Katahira ; M. Fukasawa ; J.-I. Sakuragi ; K.-I. Ishikawa ; M. Nakai ; J. A. A. Mingle ; M. Osei-Kwasi ; V. B. A. Netty ; H. Akari ; O. Hishida ; K. Tomonaga ; T. Miura ; M. Hayami

Source :

RBID : Pascal:92-0416332

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English descriptors

Abstract

A highly divergent HIV-2 designated as HIV-2[GH-2] was obtained from an AIDS-related complex (ARC) patient in Ghana. A full-length molecular clone of this isolate was obtained and a biologically active clone was constructed. Its restriction pattern differed from that of prototype HIV-2[GH-1] in 25 of 35 restriction sites, but was strikingly similar to a previously characterized HIV-2 isolate from a Ghanaian (HIV-2ALT)

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Pascal:92-0416332

Le document en format XML

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<div type="abstract" xml:lang="en">A highly divergent HIV-2 designated as HIV-2[GH-2] was obtained from an AIDS-related complex (ARC) patient in Ghana. A full-length molecular clone of this isolate was obtained and a biologically active clone was constructed. Its restriction pattern differed from that of prototype HIV-2[GH-1] in 25 of 35 restriction sites, but was strikingly similar to a previously characterized HIV-2 isolate from a Ghanaian (HIV-2
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