SidaGhanaV1, Main, Exploration, bibRecord, 000A19

Sensitivities and specificities of diagnostic tests and infection prevalence of Schistosoma haematobium estimated from data on adults in villages northwest of Accra in Ghana

Identifieur interne : 000A19 ( Main/Exploration ); précédent : 000A18; suivant : 000A20

Sensitivities and specificities of diagnostic tests and infection prevalence of Schistosoma haematobium estimated from data on adults in villages northwest of Accra in Ghana

Auteurs : Artemis Koukounari ; Joanne P. Webster ; Christl A. Donnelly ; Bethany C. Bray ; Jean Naples ; Kwabena Bosompem ; Clive Shiff

Source :

The American journal of tropical medicine and hygiene [ 0002-9637 ] ; 2009.

RBID : PMC:2726788

Abstract

Substantial uncertainties surround the sensitivities and specificities of diagnostic techniques for urinary schistosomiasis. We used Latent Class (LC) modeling to address this problem. In this study 220 adults in three villages northwest of Accra in Ghana were examined using five Schistosoma haematobium diagnostic measures: microscopic examination of urine for detection of S. haematobium eggs, dipsticks for detection of haematuria, tests for circulating antigens, serological antibody tests and ultrasound scans of the urinary system. Testing of the LC model indicated non-invariance of the performance of the diagnostic tests across different age groups while measurement invariance held for males and females and for the three villages. We therefore recommend the use of LC models for comparison between, and the identification of, the most accurate schistosomiasis diagnostic tests. Furthermore, microscopy and haematuria dipsticks were indicated through these models as the most appropriate techniques for detection of S. haematobium infection.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726788

PubMed: 19270295
PubMed Central: 2726788

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p id="P1">Substantial uncertainties surround the sensitivities and specificities of diagnostic techniques for urinary schistosomiasis. We used Latent Class (LC) modeling to address this problem. In this study 220 adults in three villages northwest of Accra in Ghana were examined using five <italic>Schistosoma haematobium</italic>
 diagnostic measures: microscopic examination of urine for detection of <italic>S. haematobium</italic>
 eggs, dipsticks for detection of haematuria, tests for circulating antigens, serological antibody tests and ultrasound scans of the urinary system. Testing of the LC model indicated non-invariance of the performance of the diagnostic tests across different age groups while measurement invariance held for males and females and for the three villages. We therefore recommend the use of LC models for comparison between, and the identification of, the most accurate schistosomiasis diagnostic tests. Furthermore, microscopy and haematuria dipsticks were indicated through these models as the most appropriate techniques for detection of <italic>S. haematobium</italic>
 infection.</p>
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<name sortKey="Webster, Joanne P" sort="Webster, Joanne P" uniqKey="Webster J" first="Joanne P." last="Webster">Joanne P. Webster</name>
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Le SIDA au Ghana (serveur d'exploration)

Sensitivities and specificities of diagnostic tests and infection prevalence of Schistosoma haematobium estimated from data on adults in villages northwest of Accra in Ghana

Sensitivities and specificities of diagnostic tests and infection prevalence of Schistosoma haematobium estimated from data on adults in villages northwest of Accra in Ghana

Source :

Abstract

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	Le SIDA au Ghana (serveur d'exploration)
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