EBV and HHV-6 Circulating Subtypes in People Living with HIV in Burkina Faso, Impact on CD4 T cell count and HIV Viral Load.
Identifieur interne : 000085 ( Main/Exploration ); précédent : 000084; suivant : 000086EBV and HHV-6 Circulating Subtypes in People Living with HIV in Burkina Faso, Impact on CD4 T cell count and HIV Viral Load.
Auteurs : Lassina Traore ; Ouéogo Nikiema ; Abdoul Karim Ouattara ; Tegwindé Rébéca Compaore ; Serge Théophile Soubeiga ; Birama Diarra ; Dorcas Obiri-Yeboah [Ghana] ; Pegdwendé Abel Sorgho ; Florencia Wendkuuni Djigma ; Cyrille Bisseye ; Albert Théophane Yonli ; Jacques SimporeSource :
- Mediterranean journal of hematology and infectious diseases [ 2035-3006 ] ; 2017.
Abstract
Epstein Barr Virus (EBV) and Human Herpes Virus 6 (HHV-6) are responsible for severe diseases, particularly in immunocompromised persons. There is limited data of the infection of these opportunistic viruses in Burkina Faso. The purpose of this study was to characterize EBV and HHV-6 subtypes and to assess their impact on CD4 T cell count, HIV-1 viral load and antiretroviral treatment in people living with HIV-1. The study population consisted of 238 HIV-positive patients with information on the CD4 T cell count, HIV-1 viral load and HAART. Venous blood samples collected in EDTA tubes were used for EBV and HHV-6 Real Time PCR subtyping. An infection rate of 6.7% (16/238) and 7.1% (17/238) were found respectively for EBV and HHV-6 in the present study. Among EBV infections, similar prevalence was noted for both subtypes (3.9% (9/238) for EBV-1 vs 4.6% (11/238) for EBV-2) with 2.1% (5/238) of co-infection. HHV-6A infection represented 6.3% (15/238) of the study population against 5.0% (12/238) for HHV-6B. EBV-2 infection was significantly higher in patients with CD4 T cell count ≥ 500 compared to those with CD4 T cell count less than 500 cells (1.65% vs 8.56%, p = 0,011). The prevalence of EBV and HHV-6 infections was almost similar in HAART-naive and HAART-experienced patients. The present study provides information on the prevalence of EBV and HHV-6 subtypes in people living with HIV-1 in Burkina Faso. The study also suggests that HAART treatment has no effect on infection with these opportunistic viruses in people living with HIV-1.
DOI: 10.4084/MJHID.2017.049
PubMed: 28894558
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000570
- to stream PubMed, to step Curation: 000570
- to stream PubMed, to step Checkpoint: 000570
- to stream Ncbi, to step Merge: 000B99
- to stream Ncbi, to step Curation: 000B99
- to stream Ncbi, to step Checkpoint: 000B99
- to stream Main, to step Merge: 000085
- to stream Main, to step Curation: 000085
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">EBV and HHV-6 Circulating Subtypes in People Living with HIV in Burkina Faso, Impact on CD4 T cell count and HIV Viral Load.</title><author><name sortKey="Traore, Lassina" sort="Traore, Lassina" uniqKey="Traore L" first="Lassina" last="Traore">Lassina Traore</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Nikiema, Oueogo" sort="Nikiema, Oueogo" uniqKey="Nikiema O" first="Ouéogo" last="Nikiema">Ouéogo Nikiema</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Ouattara, Abdoul Karim" sort="Ouattara, Abdoul Karim" uniqKey="Ouattara A" first="Abdoul Karim" last="Ouattara">Abdoul Karim Ouattara</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Compaore, Tegwinde Rebeca" sort="Compaore, Tegwinde Rebeca" uniqKey="Compaore T" first="Tegwindé Rébéca" last="Compaore">Tegwindé Rébéca Compaore</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Soubeiga, Serge Theophile" sort="Soubeiga, Serge Theophile" uniqKey="Soubeiga S" first="Serge Théophile" last="Soubeiga">Serge Théophile Soubeiga</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Diarra, Birama" sort="Diarra, Birama" uniqKey="Diarra B" first="Birama" last="Diarra">Birama Diarra</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Obiri Yeboah, Dorcas" sort="Obiri Yeboah, Dorcas" uniqKey="Obiri Yeboah D" first="Dorcas" last="Obiri-Yeboah">Dorcas Obiri-Yeboah</name><affiliation wicri:level="1"><nlm:affiliation>Deparment of Microbiology and Immunology, School of Medical Sciences, University of Cape Coast, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Deparment of Microbiology and Immunology, School of Medical Sciences, University of Cape Coast</wicri:regionArea><wicri:noRegion>University of Cape Coast</wicri:noRegion></affiliation></author><author><name sortKey="Sorgho, Pegdwende Abel" sort="Sorgho, Pegdwende Abel" uniqKey="Sorgho P" first="Pegdwendé Abel" last="Sorgho">Pegdwendé Abel Sorgho</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Djigma, Florencia Wendkuuni" sort="Djigma, Florencia Wendkuuni" uniqKey="Djigma F" first="Florencia Wendkuuni" last="Djigma">Florencia Wendkuuni Djigma</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Bisseye, Cyrille" sort="Bisseye, Cyrille" uniqKey="Bisseye C" first="Cyrille" last="Bisseye">Cyrille Bisseye</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Yonli, Albert Theophane" sort="Yonli, Albert Theophane" uniqKey="Yonli A" first="Albert Théophane" last="Yonli">Albert Théophane Yonli</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Simpore, Jacques" sort="Simpore, Jacques" uniqKey="Simpore J" first="Jacques" last="Simpore">Jacques Simpore</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28894558</idno><idno type="pmid">28894558</idno><idno type="doi">10.4084/MJHID.2017.049</idno><idno type="wicri:Area/PubMed/Corpus">000570</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000570</idno><idno type="wicri:Area/PubMed/Curation">000570</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000570</idno><idno type="wicri:Area/PubMed/Checkpoint">000570</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000570</idno><idno type="wicri:Area/Ncbi/Merge">000B99</idno><idno type="wicri:Area/Ncbi/Curation">000B99</idno><idno type="wicri:Area/Ncbi/Checkpoint">000B99</idno><idno type="wicri:doubleKey">2035-3006:2017:Traore L:ebv:and:hhv</idno><idno type="wicri:Area/Main/Merge">000085</idno><idno type="wicri:Area/Main/Curation">000085</idno><idno type="wicri:Area/Main/Exploration">000085</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">EBV and HHV-6 Circulating Subtypes in People Living with HIV in Burkina Faso, Impact on CD4 T cell count and HIV Viral Load.</title><author><name sortKey="Traore, Lassina" sort="Traore, Lassina" uniqKey="Traore L" first="Lassina" last="Traore">Lassina Traore</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Nikiema, Oueogo" sort="Nikiema, Oueogo" uniqKey="Nikiema O" first="Ouéogo" last="Nikiema">Ouéogo Nikiema</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Ouattara, Abdoul Karim" sort="Ouattara, Abdoul Karim" uniqKey="Ouattara A" first="Abdoul Karim" last="Ouattara">Abdoul Karim Ouattara</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Compaore, Tegwinde Rebeca" sort="Compaore, Tegwinde Rebeca" uniqKey="Compaore T" first="Tegwindé Rébéca" last="Compaore">Tegwindé Rébéca Compaore</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Soubeiga, Serge Theophile" sort="Soubeiga, Serge Theophile" uniqKey="Soubeiga S" first="Serge Théophile" last="Soubeiga">Serge Théophile Soubeiga</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Diarra, Birama" sort="Diarra, Birama" uniqKey="Diarra B" first="Birama" last="Diarra">Birama Diarra</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Obiri Yeboah, Dorcas" sort="Obiri Yeboah, Dorcas" uniqKey="Obiri Yeboah D" first="Dorcas" last="Obiri-Yeboah">Dorcas Obiri-Yeboah</name><affiliation wicri:level="1"><nlm:affiliation>Deparment of Microbiology and Immunology, School of Medical Sciences, University of Cape Coast, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Deparment of Microbiology and Immunology, School of Medical Sciences, University of Cape Coast</wicri:regionArea><wicri:noRegion>University of Cape Coast</wicri:noRegion></affiliation></author><author><name sortKey="Sorgho, Pegdwende Abel" sort="Sorgho, Pegdwende Abel" uniqKey="Sorgho P" first="Pegdwendé Abel" last="Sorgho">Pegdwendé Abel Sorgho</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Djigma, Florencia Wendkuuni" sort="Djigma, Florencia Wendkuuni" uniqKey="Djigma F" first="Florencia Wendkuuni" last="Djigma">Florencia Wendkuuni Djigma</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Bisseye, Cyrille" sort="Bisseye, Cyrille" uniqKey="Bisseye C" first="Cyrille" last="Bisseye">Cyrille Bisseye</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Yonli, Albert Theophane" sort="Yonli, Albert Theophane" uniqKey="Yonli A" first="Albert Théophane" last="Yonli">Albert Théophane Yonli</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author><author><name sortKey="Simpore, Jacques" sort="Simpore, Jacques" uniqKey="Simpore J" first="Jacques" last="Simpore">Jacques Simpore</name><affiliation><nlm:affiliation>Biomolecular Research Center Pietro Annigoni (CERBA).</nlm:affiliation><wicri:noCountry code="no comma">Biomolecular Research Center Pietro Annigoni (CERBA).</wicri:noCountry></affiliation></author></analytic><series><title level="j">Mediterranean journal of hematology and infectious diseases</title><idno type="ISSN">2035-3006</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Epstein Barr Virus (EBV) and Human Herpes Virus 6 (HHV-6) are responsible for severe diseases, particularly in immunocompromised persons. There is limited data of the infection of these opportunistic viruses in Burkina Faso. The purpose of this study was to characterize EBV and HHV-6 subtypes and to assess their impact on CD4 T cell count, HIV-1 viral load and antiretroviral treatment in people living with HIV-1. The study population consisted of 238 HIV-positive patients with information on the CD4 T cell count, HIV-1 viral load and HAART. Venous blood samples collected in EDTA tubes were used for EBV and HHV-6 Real Time PCR subtyping. An infection rate of 6.7% (16/238) and 7.1% (17/238) were found respectively for EBV and HHV-6 in the present study. Among EBV infections, similar prevalence was noted for both subtypes (3.9% (9/238) for EBV-1 vs 4.6% (11/238) for EBV-2) with 2.1% (5/238) of co-infection. HHV-6A infection represented 6.3% (15/238) of the study population against 5.0% (12/238) for HHV-6B. EBV-2 infection was significantly higher in patients with CD4 T cell count ≥ 500 compared to those with CD4 T cell count less than 500 cells (1.65% vs 8.56%, p = 0,011). The prevalence of EBV and HHV-6 infections was almost similar in HAART-naive and HAART-experienced patients. The present study provides information on the prevalence of EBV and HHV-6 subtypes in people living with HIV-1 in Burkina Faso. The study also suggests that HAART treatment has no effect on infection with these opportunistic viruses in people living with HIV-1.</div></front></TEI><affiliations><list><country><li>Ghana</li></country></list><tree><noCountry><name sortKey="Bisseye, Cyrille" sort="Bisseye, Cyrille" uniqKey="Bisseye C" first="Cyrille" last="Bisseye">Cyrille Bisseye</name><name sortKey="Compaore, Tegwinde Rebeca" sort="Compaore, Tegwinde Rebeca" uniqKey="Compaore T" first="Tegwindé Rébéca" last="Compaore">Tegwindé Rébéca Compaore</name><name sortKey="Diarra, Birama" sort="Diarra, Birama" uniqKey="Diarra B" first="Birama" last="Diarra">Birama Diarra</name><name sortKey="Djigma, Florencia Wendkuuni" sort="Djigma, Florencia Wendkuuni" uniqKey="Djigma F" first="Florencia Wendkuuni" last="Djigma">Florencia Wendkuuni Djigma</name><name sortKey="Nikiema, Oueogo" sort="Nikiema, Oueogo" uniqKey="Nikiema O" first="Ouéogo" last="Nikiema">Ouéogo Nikiema</name><name sortKey="Ouattara, Abdoul Karim" sort="Ouattara, Abdoul Karim" uniqKey="Ouattara A" first="Abdoul Karim" last="Ouattara">Abdoul Karim Ouattara</name><name sortKey="Simpore, Jacques" sort="Simpore, Jacques" uniqKey="Simpore J" first="Jacques" last="Simpore">Jacques Simpore</name><name sortKey="Sorgho, Pegdwende Abel" sort="Sorgho, Pegdwende Abel" uniqKey="Sorgho P" first="Pegdwendé Abel" last="Sorgho">Pegdwendé Abel Sorgho</name><name sortKey="Soubeiga, Serge Theophile" sort="Soubeiga, Serge Theophile" uniqKey="Soubeiga S" first="Serge Théophile" last="Soubeiga">Serge Théophile Soubeiga</name><name sortKey="Traore, Lassina" sort="Traore, Lassina" uniqKey="Traore L" first="Lassina" last="Traore">Lassina Traore</name><name sortKey="Yonli, Albert Theophane" sort="Yonli, Albert Theophane" uniqKey="Yonli A" first="Albert Théophane" last="Yonli">Albert Théophane Yonli</name></noCountry><country name="Ghana"><noRegion><name sortKey="Obiri Yeboah, Dorcas" sort="Obiri Yeboah, Dorcas" uniqKey="Obiri Yeboah D" first="Dorcas" last="Obiri-Yeboah">Dorcas Obiri-Yeboah</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/SidaGhanaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000085 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000085 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= SidaGhanaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:28894558
|texte= EBV and HHV-6 Circulating Subtypes in People Living with HIV in Burkina Faso, Impact on CD4 T cell count and HIV Viral Load.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28894558" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a SidaGhanaV1
| This area was generated with Dilib version V0.6.31. |  |