Clinical balance scales indicate worse postural control in people with Parkinson's disease who exhibit freezing of gait compared to those who do not: A meta-analysis.
Identifieur interne : 000586 ( Main/Exploration ); précédent : 000585; suivant : 000587Clinical balance scales indicate worse postural control in people with Parkinson's disease who exhibit freezing of gait compared to those who do not: A meta-analysis.
Auteurs : Esther M J. Bekkers [Belgique] ; Bauke W. Dijkstra [Belgique] ; Kim Dockx [Belgique] ; Elke Heremans [Belgique] ; Sabine M P. Verschueren [Belgique] ; Alice Nieuwboer [Belgique]Source :
- Gait & posture [ 1879-2219 ] ; 2017.
Descripteurs français
- KwdFr :
- MESH :
- physiopathologie : Maladie de Parkinson, Troubles neurologiques de la marche.
- Démarche, Humains, Équilibre postural, Évolution de la maladie.
English descriptors
- KwdEn :
- MESH :
- physiopathology : Gait Disorders, Neurologic, Parkinson Disease.
- Disease Progression, Gait, Humans, Postural Balance.
Abstract
Postural instability and freezing of gait (FOG) are key features of Parkinson's disease (PD) that are closely related to falls. Uncovering the postural control differences between individuals with and without FOG contributes to our understanding of the relationship between these phenomena. The objective of this meta-analysis was to investigate whether postural control deficits, as detected by clinical balance scales, were more apparent in FOG+ compared to FOG-. Furthermore, we aimed to identify whether different scales were equally sensitive to detect postural control deficits and whether medication affected postural control differentially in each subgroup. Relevant articles were identified via five electronic databases. We performed a meta-analysis on nine studies which reported clinical balance scale scores in 249 freezers and 321 non-freezers. Methodological analysis showed that in 5/9 studies disease duration differed between subgroups. Despite this drawback, postural control was found to be significantly worse in FOG+ compared to FOG-. All included clinical balance scales were found to be sufficiently sensitive to detect the postural control differences. Levodopa did not differentially affect postural control (p=0.21), as in both medication states FOG+ had worse postural stability than FOG-. However, this finding warrants a cautious interpretation given the limitations of the studies included. From subscore analysis, we found that reactive and dynamic postural control were the most affected postural control systems in FOG+. We conclude that our findings provide important evidence for pronounced postural instability in individuals with FOG, which can be easily picked up with clinical evaluation tools. Posturographic measures in well-matched subgroups are needed to highlight the exact nature of these deficits.
DOI: 10.1016/j.gaitpost.2017.05.009
PubMed: 28544951
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Clinical balance scales indicate worse postural control in people with Parkinson's disease who exhibit freezing of gait compared to those who do not: A meta-analysis.</title><author><name sortKey="Bekkers, Esther M J" sort="Bekkers, Esther M J" uniqKey="Bekkers E" first="Esther M J" last="Bekkers">Esther M J. Bekkers</name><affiliation wicri:level="1"><nlm:affiliation>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven, Belgium. Electronic address: esther.bekkers@kuleuven.be.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven</wicri:regionArea><wicri:noRegion>KU Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Dijkstra, Bauke W" sort="Dijkstra, Bauke W" uniqKey="Dijkstra B" first="Bauke W" last="Dijkstra">Bauke W. Dijkstra</name><affiliation wicri:level="1"><nlm:affiliation>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven</wicri:regionArea><wicri:noRegion>KU Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Dockx, Kim" sort="Dockx, Kim" uniqKey="Dockx K" first="Kim" last="Dockx">Kim Dockx</name><affiliation wicri:level="1"><nlm:affiliation>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven</wicri:regionArea><wicri:noRegion>KU Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Heremans, Elke" sort="Heremans, Elke" uniqKey="Heremans E" first="Elke" last="Heremans">Elke Heremans</name><affiliation wicri:level="1"><nlm:affiliation>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven</wicri:regionArea><wicri:noRegion>KU Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Verschueren, Sabine M P" sort="Verschueren, Sabine M P" uniqKey="Verschueren S" first="Sabine M P" last="Verschueren">Sabine M P. Verschueren</name><affiliation wicri:level="1"><nlm:affiliation>Research Group for Musculoskeletal Research, Department of Rehabilitation Sciences, KU Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Research Group for Musculoskeletal Research, Department of Rehabilitation Sciences, KU Leuven</wicri:regionArea><wicri:noRegion>KU Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Nieuwboer, Alice" sort="Nieuwboer, Alice" uniqKey="Nieuwboer A" first="Alice" last="Nieuwboer">Alice Nieuwboer</name><affiliation wicri:level="1"><nlm:affiliation>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven</wicri:regionArea><wicri:noRegion>KU Leuven</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28544951</idno><idno type="pmid">28544951</idno><idno type="doi">10.1016/j.gaitpost.2017.05.009</idno><idno type="wicri:Area/Main/Corpus">000529</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000529</idno><idno type="wicri:Area/Main/Curation">000529</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000529</idno><idno type="wicri:Area/Main/Exploration">000529</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Clinical balance scales indicate worse postural control in people with Parkinson's disease who exhibit freezing of gait compared to those who do not: A meta-analysis.</title><author><name sortKey="Bekkers, Esther M J" sort="Bekkers, Esther M J" uniqKey="Bekkers E" first="Esther M J" last="Bekkers">Esther M J. Bekkers</name><affiliation wicri:level="1"><nlm:affiliation>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven, Belgium. Electronic address: esther.bekkers@kuleuven.be.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven</wicri:regionArea><wicri:noRegion>KU Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Dijkstra, Bauke W" sort="Dijkstra, Bauke W" uniqKey="Dijkstra B" first="Bauke W" last="Dijkstra">Bauke W. Dijkstra</name><affiliation wicri:level="1"><nlm:affiliation>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven</wicri:regionArea><wicri:noRegion>KU Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Dockx, Kim" sort="Dockx, Kim" uniqKey="Dockx K" first="Kim" last="Dockx">Kim Dockx</name><affiliation wicri:level="1"><nlm:affiliation>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven</wicri:regionArea><wicri:noRegion>KU Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Heremans, Elke" sort="Heremans, Elke" uniqKey="Heremans E" first="Elke" last="Heremans">Elke Heremans</name><affiliation wicri:level="1"><nlm:affiliation>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven</wicri:regionArea><wicri:noRegion>KU Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Verschueren, Sabine M P" sort="Verschueren, Sabine M P" uniqKey="Verschueren S" first="Sabine M P" last="Verschueren">Sabine M P. Verschueren</name><affiliation wicri:level="1"><nlm:affiliation>Research Group for Musculoskeletal Research, Department of Rehabilitation Sciences, KU Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Research Group for Musculoskeletal Research, Department of Rehabilitation Sciences, KU Leuven</wicri:regionArea><wicri:noRegion>KU Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Nieuwboer, Alice" sort="Nieuwboer, Alice" uniqKey="Nieuwboer A" first="Alice" last="Nieuwboer">Alice Nieuwboer</name><affiliation wicri:level="1"><nlm:affiliation>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven</wicri:regionArea><wicri:noRegion>KU Leuven</wicri:noRegion></affiliation></author></analytic><series><title level="j">Gait & posture</title><idno type="eISSN">1879-2219</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Disease Progression (MeSH)</term><term>Gait (MeSH)</term><term>Gait Disorders, Neurologic (physiopathology)</term><term>Humans (MeSH)</term><term>Parkinson Disease (physiopathology)</term><term>Postural Balance (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Démarche (MeSH)</term><term>Humains (MeSH)</term><term>Maladie de Parkinson (physiopathologie)</term><term>Troubles neurologiques de la marche (physiopathologie)</term><term>Équilibre postural (MeSH)</term><term>Évolution de la maladie (MeSH)</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Maladie de Parkinson</term><term>Troubles neurologiques de la marche</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Gait Disorders, Neurologic</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Disease Progression</term><term>Gait</term><term>Humans</term><term>Postural Balance</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Démarche</term><term>Humains</term><term>Équilibre postural</term><term>Évolution de la maladie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Postural instability and freezing of gait (FOG) are key features of Parkinson's disease (PD) that are closely related to falls. Uncovering the postural control differences between individuals with and without FOG contributes to our understanding of the relationship between these phenomena. The objective of this meta-analysis was to investigate whether postural control deficits, as detected by clinical balance scales, were more apparent in FOG+ compared to FOG-. Furthermore, we aimed to identify whether different scales were equally sensitive to detect postural control deficits and whether medication affected postural control differentially in each subgroup. Relevant articles were identified via five electronic databases. We performed a meta-analysis on nine studies which reported clinical balance scale scores in 249 freezers and 321 non-freezers. Methodological analysis showed that in 5/9 studies disease duration differed between subgroups. Despite this drawback, postural control was found to be significantly worse in FOG+ compared to FOG-. All included clinical balance scales were found to be sufficiently sensitive to detect the postural control differences. Levodopa did not differentially affect postural control (p=0.21), as in both medication states FOG+ had worse postural stability than FOG-. However, this finding warrants a cautious interpretation given the limitations of the studies included. From subscore analysis, we found that reactive and dynamic postural control were the most affected postural control systems in FOG+. We conclude that our findings provide important evidence for pronounced postural instability in individuals with FOG, which can be easily picked up with clinical evaluation tools. Posturographic measures in well-matched subgroups are needed to highlight the exact nature of these deficits.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">28544951</PMID><DateCompleted><Year>2018</Year><Month>02</Month><Day>20</Day></DateCompleted><DateRevised><Year>2018</Year><Month>12</Month><Day>02</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1879-2219</ISSN><JournalIssue CitedMedium="Internet"><Volume>56</Volume><PubDate><Year>2017</Year><Month>07</Month></PubDate></JournalIssue><Title>Gait & posture</Title><ISOAbbreviation>Gait Posture</ISOAbbreviation></Journal><ArticleTitle>Clinical balance scales indicate worse postural control in people with Parkinson's disease who exhibit freezing of gait compared to those who do not: A meta-analysis.</ArticleTitle><Pagination><MedlinePgn>134-140</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0966-6362(17)30191-1</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.gaitpost.2017.05.009</ELocationID><Abstract><AbstractText>Postural instability and freezing of gait (FOG) are key features of Parkinson's disease (PD) that are closely related to falls. Uncovering the postural control differences between individuals with and without FOG contributes to our understanding of the relationship between these phenomena. The objective of this meta-analysis was to investigate whether postural control deficits, as detected by clinical balance scales, were more apparent in FOG+ compared to FOG-. Furthermore, we aimed to identify whether different scales were equally sensitive to detect postural control deficits and whether medication affected postural control differentially in each subgroup. Relevant articles were identified via five electronic databases. We performed a meta-analysis on nine studies which reported clinical balance scale scores in 249 freezers and 321 non-freezers. Methodological analysis showed that in 5/9 studies disease duration differed between subgroups. Despite this drawback, postural control was found to be significantly worse in FOG+ compared to FOG-. All included clinical balance scales were found to be sufficiently sensitive to detect the postural control differences. Levodopa did not differentially affect postural control (p=0.21), as in both medication states FOG+ had worse postural stability than FOG-. However, this finding warrants a cautious interpretation given the limitations of the studies included. From subscore analysis, we found that reactive and dynamic postural control were the most affected postural control systems in FOG+. We conclude that our findings provide important evidence for pronounced postural instability in individuals with FOG, which can be easily picked up with clinical evaluation tools. Posturographic measures in well-matched subgroups are needed to highlight the exact nature of these deficits.</AbstractText><CopyrightInformation>Copyright © 2017 Elsevier B.V. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bekkers</LastName><ForeName>Esther M J</ForeName><Initials>EMJ</Initials><AffiliationInfo><Affiliation>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven, Belgium. Electronic address: esther.bekkers@kuleuven.be.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dijkstra</LastName><ForeName>Bauke W</ForeName><Initials>BW</Initials><AffiliationInfo><Affiliation>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dockx</LastName><ForeName>Kim</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Heremans</LastName><ForeName>Elke</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Verschueren</LastName><ForeName>Sabine M P</ForeName><Initials>SMP</Initials><AffiliationInfo><Affiliation>Research Group for Musculoskeletal Research, Department of Rehabilitation Sciences, KU Leuven, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nieuwboer</LastName><ForeName>Alice</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven, Belgium.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>05</Month><Day>11</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Gait Posture</MedlineTA><NlmUniqueID>9416830</NlmUniqueID><ISSNLinking>0966-6362</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D018450" MajorTopicYN="N">Disease Progression</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005684" MajorTopicYN="Y">Gait</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020233" MajorTopicYN="N">Gait Disorders, Neurologic</DescriptorName><QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName><QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004856" MajorTopicYN="Y">Postural Balance</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">Clinical balance scales</Keyword><Keyword MajorTopicYN="Y">Freezing of gait</Keyword><Keyword MajorTopicYN="Y">Parkinson’s disease</Keyword><Keyword MajorTopicYN="Y">Postural control</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>12</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2017</Year><Month>05</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>05</Month><Day>09</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>5</Month><Day>26</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2018</Year><Month>2</Month><Day>21</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>5</Month><Day>26</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28544951</ArticleId><ArticleId IdType="pii">S0966-6362(17)30191-1</ArticleId><ArticleId IdType="doi">10.1016/j.gaitpost.2017.05.009</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Belgique</li></country></list><tree><country name="Belgique"><noRegion><name sortKey="Bekkers, Esther M J" sort="Bekkers, Esther M J" uniqKey="Bekkers E" first="Esther M J" last="Bekkers">Esther M J. Bekkers</name></noRegion><name sortKey="Dijkstra, Bauke W" sort="Dijkstra, Bauke W" uniqKey="Dijkstra B" first="Bauke W" last="Dijkstra">Bauke W. Dijkstra</name><name sortKey="Dockx, Kim" sort="Dockx, Kim" uniqKey="Dockx K" first="Kim" last="Dockx">Kim Dockx</name><name sortKey="Heremans, Elke" sort="Heremans, Elke" uniqKey="Heremans E" first="Elke" last="Heremans">Elke Heremans</name><name sortKey="Nieuwboer, Alice" sort="Nieuwboer, Alice" uniqKey="Nieuwboer A" first="Alice" last="Nieuwboer">Alice Nieuwboer</name><name sortKey="Verschueren, Sabine M P" sort="Verschueren, Sabine M P" uniqKey="Verschueren S" first="Sabine M P" last="Verschueren">Sabine M P. Verschueren</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PosturoV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000586 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000586 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= PosturoV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:28544951
|texte= Clinical balance scales indicate worse postural control in people with Parkinson's disease who exhibit freezing of gait compared to those who do not: A meta-analysis.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28544951" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a PosturoV1
| This area was generated with Dilib version V0.6.37. |  |