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Vestibular and balance findings in nonsymptomatic workers exposed to styrene and dichloromethane.

Identifieur interne : 000C13 ( Main/Exploration ); précédent : 000C12; suivant : 000C14

Vestibular and balance findings in nonsymptomatic workers exposed to styrene and dichloromethane.

Auteurs : Ewa Zamyslowska-Szmytke [Pologne] ; Mariola Sliwinska-Kowalska

Source :

RBID : pubmed:21929376

Descripteurs français

English descriptors

Abstract

OBJECTIVE

The aim of our study was to assess the vestibular and balance system in non-symptomatic workers exposed to styrene and dichloromethane at the workplace.

DESIGN

Subjects underwent videonystagmography including saccades, smooth pursuit (SP), optokinetic test (OKN), gaze nystagmus assessment, bithermal caloric test, and static posturography.

STUDY SAMPLE

Study groups included 74 workers in plastics manufacturing, aged 40 (SD 8) years, exposed to styrene and dichloromethane, and the reference group of 49 non-exposed subjects, aged 36 (SD 10) years.

RESULTS

More than 60% of exposed and non-symptomatic workers revealed abnormal results of vestibular tests. Saccadic latency elongation (p = 0.0098), lower gain in SP (p = 0.0037) and OKN (p = 0.0000) were more common in the exposed group, as well as lower reactivity (p = 0.0337) and mean slow phase velocity of caloric nystagmus. Static posturography revealed higher sway velocities in the test with eyes closed, on foam and worse results of three from five limit of stability tests. No relationship between chemicals exposure and vestibular and balance test results was found.

CONCLUSIONS

In principle, our findings indicate the possibility of high-level deficits in the central part of vestibular system. Lower vestibular reactivity may suggest that bilateral vestibular hypofunction might also be the possible consequence of solvent exposure.


DOI: 10.3109/14992027.2011.599872
PubMed: 21929376


Affiliations:


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Le document en format XML

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<term>Facteurs de risque (MeSH)</term>
<term>Facteurs temps (MeSH)</term>
<term>Femelle (MeSH)</term>
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<term>Maladies asymptomatiques (MeSH)</term>
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<term>Maladies professionnelles (induit chimiquement)</term>
<term>Maladies professionnelles (physiopathologie)</term>
<term>Maladies vestibulaires (diagnostic)</term>
<term>Maladies vestibulaires (induit chimiquement)</term>
<term>Maladies vestibulaires (physiopathologie)</term>
<term>Mâle (MeSH)</term>
<term>Nystagmus optocinétique (effets des médicaments et des substances chimiques)</term>
<term>Nystagmus physiologique (effets des médicaments et des substances chimiques)</term>
<term>Pologne (MeSH)</term>
<term>Poursuite oculaire (effets des médicaments et des substances chimiques)</term>
<term>Saccades (effets des médicaments et des substances chimiques)</term>
<term>Solvants (effets indésirables)</term>
<term>Styrène (effets indésirables)</term>
<term>Troubles sensitifs (diagnostic)</term>
<term>Troubles sensitifs (induit chimiquement)</term>
<term>Troubles sensitifs (physiopathologie)</term>
<term>Épreuves vestibulaires (MeSH)</term>
<term>Équilibre postural (effets des médicaments et des substances chimiques)</term>
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<term>Methylene Chloride</term>
<term>Solvents</term>
<term>Styrene</term>
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<term>Poursuite oculaire</term>
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<term>Équilibre postural</term>
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<b>OBJECTIVE</b>
</p>
<p>The aim of our study was to assess the vestibular and balance system in non-symptomatic workers exposed to styrene and dichloromethane at the workplace.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>DESIGN</b>
</p>
<p>Subjects underwent videonystagmography including saccades, smooth pursuit (SP), optokinetic test (OKN), gaze nystagmus assessment, bithermal caloric test, and static posturography.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>STUDY SAMPLE</b>
</p>
<p>Study groups included 74 workers in plastics manufacturing, aged 40 (SD 8) years, exposed to styrene and dichloromethane, and the reference group of 49 non-exposed subjects, aged 36 (SD 10) years.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>RESULTS</b>
</p>
<p>More than 60% of exposed and non-symptomatic workers revealed abnormal results of vestibular tests. Saccadic latency elongation (p = 0.0098), lower gain in SP (p = 0.0037) and OKN (p = 0.0000) were more common in the exposed group, as well as lower reactivity (p = 0.0337) and mean slow phase velocity of caloric nystagmus. Static posturography revealed higher sway velocities in the test with eyes closed, on foam and worse results of three from five limit of stability tests. No relationship between chemicals exposure and vestibular and balance test results was found.</p>
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<div type="abstract" xml:lang="en">
<p>
<b>CONCLUSIONS</b>
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<p>In principle, our findings indicate the possibility of high-level deficits in the central part of vestibular system. Lower vestibular reactivity may suggest that bilateral vestibular hypofunction might also be the possible consequence of solvent exposure.</p>
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<name sortKey="Sliwinska Kowalska, Mariola" sort="Sliwinska Kowalska, Mariola" uniqKey="Sliwinska Kowalska M" first="Mariola" last="Sliwinska-Kowalska">Mariola Sliwinska-Kowalska</name>
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<country name="Pologne">
<noRegion>
<name sortKey="Zamyslowska Szmytke, Ewa" sort="Zamyslowska Szmytke, Ewa" uniqKey="Zamyslowska Szmytke E" first="Ewa" last="Zamyslowska-Szmytke">Ewa Zamyslowska-Szmytke</name>
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