Cluster analysis of auditory and vestibular test results in definite Menière's disease.
Identifieur interne : 000C13 ( Main/Corpus ); précédent : 000C12; suivant : 000C14Cluster analysis of auditory and vestibular test results in definite Menière's disease.
Auteurs : Lourdes Montes-Jovellar ; Francisco Guillen-Grima ; Nicolas Perez-FernandezSource :
- The Laryngoscope [ 1531-4995 ] ; 2011.
English descriptors
- KwdEn :
- Audiometry (MeSH), Cluster Analysis (MeSH), Disability Evaluation (MeSH), Female (MeSH), Hearing Loss (complications), Hearing Loss (diagnosis), Humans (MeSH), Male (MeSH), Meniere Disease (classification), Meniere Disease (diagnosis), Meniere Disease (physiopathology), Middle Aged (MeSH), Postural Balance (MeSH), Predictive Value of Tests (MeSH), Sensitivity and Specificity (MeSH), Vestibular Function Tests (MeSH).
- MESH :
- classification : Meniere Disease.
- complications : Hearing Loss.
- diagnosis : Hearing Loss, Meniere Disease.
- physiopathology : Meniere Disease.
- Audiometry, Cluster Analysis, Disability Evaluation, Female, Humans, Male, Middle Aged, Postural Balance, Predictive Value of Tests, Sensitivity and Specificity, Vestibular Function Tests.
Abstract
OBJECTIVES/HYPOTHESIS
To determine whether patients with Menière's disease can be grouped into distinct subtypes based on a cluster analysis of distinct disease parameters.
STUDY DESIGN
Prospective study at a tertiary center associated with a university hospital.
METHODS
The study included 153 patients diagnosed with unilateral definite Menière's disease. The main variables employed were taken from auditory, vestibular, posturographic, and disability assessments.
RESULTS
A four-cluster solution best fitted the data. Each cluster represented a distinct patient profile. Cluster 1 patients (13.1%) were the eldest, with the worst hearing bilaterally and good vestibular function but with a significant postural impact and a low level of disability. Cluster 2 patients (41.2%) were the least affected in all the parameters that were close to normal. Cluster 3 patients (34.6%) were the most affected, experiencing frequent and intense vertigo attacks, and they were visually dependent. Cluster 4 patients (11.1%) had strong asymmetric hearing between both ears and the most uncompensated vestibular deficit; they were moderately disabled.
CONCLUSIONS
We have identified four distinct profiles of patients with definite Menière's disease that we consider as "mildly active elderly," "mildly active young," "active compensated," and "active uncompensated." We have demonstrated that only in a restricted population of patients can the American Academy of Otolaryngology-Head and Neck Surgery staging system provide analysis of subtypes of the disease.
DOI: 10.1002/lary.21844
PubMed: 21792974
Links to Exploration step
pubmed:21792974Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Cluster analysis of auditory and vestibular test results in definite Menière's disease.</title>
<author><name sortKey="Montes Jovellar, Lourdes" sort="Montes Jovellar, Lourdes" uniqKey="Montes Jovellar L" first="Lourdes" last="Montes-Jovellar">Lourdes Montes-Jovellar</name>
<affiliation><nlm:affiliation>Department of Otorhinolaryngology, Clínica Universidad de Navarra, University Hospital and Medical School, University of Navarra, Navarra, Spain.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Guillen Grima, Francisco" sort="Guillen Grima, Francisco" uniqKey="Guillen Grima F" first="Francisco" last="Guillen-Grima">Francisco Guillen-Grima</name>
</author>
<author><name sortKey="Perez Fernandez, Nicolas" sort="Perez Fernandez, Nicolas" uniqKey="Perez Fernandez N" first="Nicolas" last="Perez-Fernandez">Nicolas Perez-Fernandez</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2011">2011</date>
<idno type="RBID">pubmed:21792974</idno>
<idno type="pmid">21792974</idno>
<idno type="doi">10.1002/lary.21844</idno>
<idno type="wicri:Area/Main/Corpus">000C13</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000C13</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Cluster analysis of auditory and vestibular test results in definite Menière's disease.</title>
<author><name sortKey="Montes Jovellar, Lourdes" sort="Montes Jovellar, Lourdes" uniqKey="Montes Jovellar L" first="Lourdes" last="Montes-Jovellar">Lourdes Montes-Jovellar</name>
<affiliation><nlm:affiliation>Department of Otorhinolaryngology, Clínica Universidad de Navarra, University Hospital and Medical School, University of Navarra, Navarra, Spain.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Guillen Grima, Francisco" sort="Guillen Grima, Francisco" uniqKey="Guillen Grima F" first="Francisco" last="Guillen-Grima">Francisco Guillen-Grima</name>
</author>
<author><name sortKey="Perez Fernandez, Nicolas" sort="Perez Fernandez, Nicolas" uniqKey="Perez Fernandez N" first="Nicolas" last="Perez-Fernandez">Nicolas Perez-Fernandez</name>
</author>
</analytic>
<series><title level="j">The Laryngoscope</title>
<idno type="eISSN">1531-4995</idno>
<imprint><date when="2011" type="published">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Audiometry (MeSH)</term>
<term>Cluster Analysis (MeSH)</term>
<term>Disability Evaluation (MeSH)</term>
<term>Female (MeSH)</term>
<term>Hearing Loss (complications)</term>
<term>Hearing Loss (diagnosis)</term>
<term>Humans (MeSH)</term>
<term>Male (MeSH)</term>
<term>Meniere Disease (classification)</term>
<term>Meniere Disease (diagnosis)</term>
<term>Meniere Disease (physiopathology)</term>
<term>Middle Aged (MeSH)</term>
<term>Postural Balance (MeSH)</term>
<term>Predictive Value of Tests (MeSH)</term>
<term>Sensitivity and Specificity (MeSH)</term>
<term>Vestibular Function Tests (MeSH)</term>
</keywords>
<keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Meniere Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Hearing Loss</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Hearing Loss</term>
<term>Meniere Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Meniere Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Audiometry</term>
<term>Cluster Analysis</term>
<term>Disability Evaluation</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Postural Balance</term>
<term>Predictive Value of Tests</term>
<term>Sensitivity and Specificity</term>
<term>Vestibular Function Tests</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><b>OBJECTIVES/HYPOTHESIS</b>
</p>
<p>To determine whether patients with Menière's disease can be grouped into distinct subtypes based on a cluster analysis of distinct disease parameters.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>STUDY DESIGN</b>
</p>
<p>Prospective study at a tertiary center associated with a university hospital.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>The study included 153 patients diagnosed with unilateral definite Menière's disease. The main variables employed were taken from auditory, vestibular, posturographic, and disability assessments.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>A four-cluster solution best fitted the data. Each cluster represented a distinct patient profile. Cluster 1 patients (13.1%) were the eldest, with the worst hearing bilaterally and good vestibular function but with a significant postural impact and a low level of disability. Cluster 2 patients (41.2%) were the least affected in all the parameters that were close to normal. Cluster 3 patients (34.6%) were the most affected, experiencing frequent and intense vertigo attacks, and they were visually dependent. Cluster 4 patients (11.1%) had strong asymmetric hearing between both ears and the most uncompensated vestibular deficit; they were moderately disabled.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b>
</p>
<p>We have identified four distinct profiles of patients with definite Menière's disease that we consider as "mildly active elderly," "mildly active young," "active compensated," and "active uncompensated." We have demonstrated that only in a restricted population of patients can the American Academy of Otolaryngology-Head and Neck Surgery staging system provide analysis of subtypes of the disease.</p>
</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">21792974</PMID>
<DateCompleted><Year>2011</Year>
<Month>09</Month>
<Day>23</Day>
</DateCompleted>
<DateRevised><Year>2011</Year>
<Month>07</Month>
<Day>27</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1531-4995</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>121</Volume>
<Issue>8</Issue>
<PubDate><Year>2011</Year>
<Month>Aug</Month>
</PubDate>
</JournalIssue>
<Title>The Laryngoscope</Title>
<ISOAbbreviation>Laryngoscope</ISOAbbreviation>
</Journal>
<ArticleTitle>Cluster analysis of auditory and vestibular test results in definite Menière's disease.</ArticleTitle>
<Pagination><MedlinePgn>1810-7</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1002/lary.21844</ELocationID>
<Abstract><AbstractText Label="OBJECTIVES/HYPOTHESIS" NlmCategory="OBJECTIVE">To determine whether patients with Menière's disease can be grouped into distinct subtypes based on a cluster analysis of distinct disease parameters.</AbstractText>
<AbstractText Label="STUDY DESIGN" NlmCategory="METHODS">Prospective study at a tertiary center associated with a university hospital.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">The study included 153 patients diagnosed with unilateral definite Menière's disease. The main variables employed were taken from auditory, vestibular, posturographic, and disability assessments.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">A four-cluster solution best fitted the data. Each cluster represented a distinct patient profile. Cluster 1 patients (13.1%) were the eldest, with the worst hearing bilaterally and good vestibular function but with a significant postural impact and a low level of disability. Cluster 2 patients (41.2%) were the least affected in all the parameters that were close to normal. Cluster 3 patients (34.6%) were the most affected, experiencing frequent and intense vertigo attacks, and they were visually dependent. Cluster 4 patients (11.1%) had strong asymmetric hearing between both ears and the most uncompensated vestibular deficit; they were moderately disabled.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">We have identified four distinct profiles of patients with definite Menière's disease that we consider as "mildly active elderly," "mildly active young," "active compensated," and "active uncompensated." We have demonstrated that only in a restricted population of patients can the American Academy of Otolaryngology-Head and Neck Surgery staging system provide analysis of subtypes of the disease.</AbstractText>
<CopyrightInformation>Copyright © 2011 The American Laryngological, Rhinological, and Otological Society, Inc.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Montes-Jovellar</LastName>
<ForeName>Lourdes</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Department of Otorhinolaryngology, Clínica Universidad de Navarra, University Hospital and Medical School, University of Navarra, Navarra, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Guillen-Grima</LastName>
<ForeName>Francisco</ForeName>
<Initials>F</Initials>
</Author>
<Author ValidYN="Y"><LastName>Perez-Fernandez</LastName>
<ForeName>Nicolas</ForeName>
<Initials>N</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Laryngoscope</MedlineTA>
<NlmUniqueID>8607378</NlmUniqueID>
<ISSNLinking>0023-852X</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D001299" MajorTopicYN="Y">Audiometry</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016000" MajorTopicYN="N">Cluster Analysis</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004185" MajorTopicYN="N">Disability Evaluation</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D034381" MajorTopicYN="N">Hearing Loss</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008575" MajorTopicYN="N">Meniere Disease</DescriptorName>
<QualifierName UI="Q000145" MajorTopicYN="N">classification</QualifierName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004856" MajorTopicYN="N">Postural Balance</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011237" MajorTopicYN="N">Predictive Value of Tests</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012680" MajorTopicYN="N">Sensitivity and Specificity</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014724" MajorTopicYN="Y">Vestibular Function Tests</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2011</Year>
<Month>7</Month>
<Day>28</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2011</Year>
<Month>7</Month>
<Day>28</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2011</Year>
<Month>9</Month>
<Day>29</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">21792974</ArticleId>
<ArticleId IdType="doi">10.1002/lary.21844</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PosturoV1/Data/Main/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000C13 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Corpus/biblio.hfd -nk 000C13 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= PosturoV1 |flux= Main |étape= Corpus |type= RBID |clé= pubmed:21792974 |texte= Cluster analysis of auditory and vestibular test results in definite Menière's disease. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Corpus/RBID.i -Sk "pubmed:21792974" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Corpus/biblio.hfd \ | NlmPubMed2Wicri -a PosturoV1
![]() | This area was generated with Dilib version V0.6.37. | ![]() |