Task-dependent deterioration of balance underpinning cognitive-postural interference in MS.
Identifieur interne : 000633 ( Main/Corpus ); précédent : 000632; suivant : 000634Task-dependent deterioration of balance underpinning cognitive-postural interference in MS.
Auteurs : Luca Prosperini ; Letizia Castelli ; Francesca De Luca ; Francesca Fabiano ; Ilaria Ferrante ; Laura De GiglioSource :
- Neurology [ 1526-632X ] ; 2016.
English descriptors
- KwdEn :
- Attention (MeSH), Cognition (MeSH), Cross-Sectional Studies (MeSH), Executive Function (MeSH), Female (MeSH), Humans (MeSH), Male (MeSH), Middle Aged (MeSH), Motor Activity (MeSH), Multiple Sclerosis (physiopathology), Multiple Sclerosis (psychology), Neuropsychological Tests (MeSH), Postural Balance (MeSH), Reproducibility of Results (MeSH).
- MESH :
- physiopathology : Multiple Sclerosis.
- psychology : Multiple Sclerosis.
- Attention, Cognition, Cross-Sectional Studies, Executive Function, Female, Humans, Male, Middle Aged, Motor Activity, Neuropsychological Tests, Postural Balance, Reproducibility of Results.
Abstract
OBJECTIVE
To investigate which concurrent cognitive task (if any) had the most detrimental effect on balance control of patients with multiple sclerosis (MS).
METHODS
In a dual-task experiment, we evaluated the reciprocal effect of simultaneously performing a postural and a cognitive task on balance and cognition in 52 patients and 26 sex- and age-matched controls. Balance was assessed by static posturography, while cognition was scored as number of correct items at 3 different neuropsychological tests, i.e., the Symbol Digit Modalities Test (SDMT), word list generation (WLG), and Stroop Color-Word Test (SCWT).
RESULTS
In both single and dual-task conditions, the patients had larger postural sway and worse scores at SDMT, WLG, and SCWT than the controls (p < 0.05). Test-retest reliability was excellent for all dual-task metrics (85%-94%). By means of 2-way analyses of the variance, we found significant main effects of dual task on balance, regardless of the concurrent cognitive task (p < 0.001). There was no main effect of dual task on cognitive performance across all the 3 task conditions (p ≥ 0.1). We observed a significant condition-by-group interaction effect on balance only when the SCWT was administered as concurrent task (p = 0.01), indicating a greater dual-task cost of balance for the patients than controls (53% vs 28%, p = 0.04).
CONCLUSIONS
We suggest that tasks exploring executive functions involved in discriminating conflicting stimuli may be the most suitable to unmask the cognitive-postural interference phenomenon in patients with MS. This may support the hypothesis that MS-related damage constrains brain networks to subserve both postural control and executive functions.
DOI: 10.1212/WNL.0000000000003090
PubMed: 27521436
Links to Exploration step
pubmed:27521436Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Task-dependent deterioration of balance underpinning cognitive-postural interference in MS.</title><author><name sortKey="Prosperini, Luca" sort="Prosperini, Luca" uniqKey="Prosperini L" first="Luca" last="Prosperini">Luca Prosperini</name><affiliation><nlm:affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy. luca.prosperini@uniroma1.it.</nlm:affiliation></affiliation></author><author><name sortKey="Castelli, Letizia" sort="Castelli, Letizia" uniqKey="Castelli L" first="Letizia" last="Castelli">Letizia Castelli</name><affiliation><nlm:affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="De Luca, Francesca" sort="De Luca, Francesca" uniqKey="De Luca F" first="Francesca" last="De Luca">Francesca De Luca</name><affiliation><nlm:affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Fabiano, Francesca" sort="Fabiano, Francesca" uniqKey="Fabiano F" first="Francesca" last="Fabiano">Francesca Fabiano</name><affiliation><nlm:affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Ferrante, Ilaria" sort="Ferrante, Ilaria" uniqKey="Ferrante I" first="Ilaria" last="Ferrante">Ilaria Ferrante</name><affiliation><nlm:affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="De Giglio, Laura" sort="De Giglio, Laura" uniqKey="De Giglio L" first="Laura" last="De Giglio">Laura De Giglio</name><affiliation><nlm:affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:27521436</idno><idno type="pmid">27521436</idno><idno type="doi">10.1212/WNL.0000000000003090</idno><idno type="wicri:Area/Main/Corpus">000633</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000633</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Task-dependent deterioration of balance underpinning cognitive-postural interference in MS.</title><author><name sortKey="Prosperini, Luca" sort="Prosperini, Luca" uniqKey="Prosperini L" first="Luca" last="Prosperini">Luca Prosperini</name><affiliation><nlm:affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy. luca.prosperini@uniroma1.it.</nlm:affiliation></affiliation></author><author><name sortKey="Castelli, Letizia" sort="Castelli, Letizia" uniqKey="Castelli L" first="Letizia" last="Castelli">Letizia Castelli</name><affiliation><nlm:affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="De Luca, Francesca" sort="De Luca, Francesca" uniqKey="De Luca F" first="Francesca" last="De Luca">Francesca De Luca</name><affiliation><nlm:affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Fabiano, Francesca" sort="Fabiano, Francesca" uniqKey="Fabiano F" first="Francesca" last="Fabiano">Francesca Fabiano</name><affiliation><nlm:affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Ferrante, Ilaria" sort="Ferrante, Ilaria" uniqKey="Ferrante I" first="Ilaria" last="Ferrante">Ilaria Ferrante</name><affiliation><nlm:affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="De Giglio, Laura" sort="De Giglio, Laura" uniqKey="De Giglio L" first="Laura" last="De Giglio">Laura De Giglio</name><affiliation><nlm:affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Neurology</title><idno type="eISSN">1526-632X</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Attention (MeSH)</term><term>Cognition (MeSH)</term><term>Cross-Sectional Studies (MeSH)</term><term>Executive Function (MeSH)</term><term>Female (MeSH)</term><term>Humans (MeSH)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Motor Activity (MeSH)</term><term>Multiple Sclerosis (physiopathology)</term><term>Multiple Sclerosis (psychology)</term><term>Neuropsychological Tests (MeSH)</term><term>Postural Balance (MeSH)</term><term>Reproducibility of Results (MeSH)</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Multiple Sclerosis</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Multiple Sclerosis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Attention</term><term>Cognition</term><term>Cross-Sectional Studies</term><term>Executive Function</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Motor Activity</term><term>Neuropsychological Tests</term><term>Postural Balance</term><term>Reproducibility of Results</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b></p><p>To investigate which concurrent cognitive task (if any) had the most detrimental effect on balance control of patients with multiple sclerosis (MS).</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>In a dual-task experiment, we evaluated the reciprocal effect of simultaneously performing a postural and a cognitive task on balance and cognition in 52 patients and 26 sex- and age-matched controls. Balance was assessed by static posturography, while cognition was scored as number of correct items at 3 different neuropsychological tests, i.e., the Symbol Digit Modalities Test (SDMT), word list generation (WLG), and Stroop Color-Word Test (SCWT).</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>In both single and dual-task conditions, the patients had larger postural sway and worse scores at SDMT, WLG, and SCWT than the controls (p < 0.05). Test-retest reliability was excellent for all dual-task metrics (85%-94%). By means of 2-way analyses of the variance, we found significant main effects of dual task on balance, regardless of the concurrent cognitive task (p < 0.001). There was no main effect of dual task on cognitive performance across all the 3 task conditions (p ≥ 0.1). We observed a significant condition-by-group interaction effect on balance only when the SCWT was administered as concurrent task (p = 0.01), indicating a greater dual-task cost of balance for the patients than controls (53% vs 28%, p = 0.04).</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>We suggest that tasks exploring executive functions involved in discriminating conflicting stimuli may be the most suitable to unmask the cognitive-postural interference phenomenon in patients with MS. This may support the hypothesis that MS-related damage constrains brain networks to subserve both postural control and executive functions.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27521436</PMID><DateCompleted><Year>2017</Year><Month>06</Month><Day>05</Day></DateCompleted><DateRevised><Year>2017</Year><Month>06</Month><Day>05</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1526-632X</ISSN><JournalIssue CitedMedium="Internet"><Volume>87</Volume><Issue>11</Issue><PubDate><Year>2016</Year><Month>Sep</Month><Day>13</Day></PubDate></JournalIssue><Title>Neurology</Title><ISOAbbreviation>Neurology</ISOAbbreviation></Journal><ArticleTitle>Task-dependent deterioration of balance underpinning cognitive-postural interference in MS.</ArticleTitle><Pagination><MedlinePgn>1085-92</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1212/WNL.0000000000003090</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To investigate which concurrent cognitive task (if any) had the most detrimental effect on balance control of patients with multiple sclerosis (MS).</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">In a dual-task experiment, we evaluated the reciprocal effect of simultaneously performing a postural and a cognitive task on balance and cognition in 52 patients and 26 sex- and age-matched controls. Balance was assessed by static posturography, while cognition was scored as number of correct items at 3 different neuropsychological tests, i.e., the Symbol Digit Modalities Test (SDMT), word list generation (WLG), and Stroop Color-Word Test (SCWT).</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">In both single and dual-task conditions, the patients had larger postural sway and worse scores at SDMT, WLG, and SCWT than the controls (p < 0.05). Test-retest reliability was excellent for all dual-task metrics (85%-94%). By means of 2-way analyses of the variance, we found significant main effects of dual task on balance, regardless of the concurrent cognitive task (p < 0.001). There was no main effect of dual task on cognitive performance across all the 3 task conditions (p ≥ 0.1). We observed a significant condition-by-group interaction effect on balance only when the SCWT was administered as concurrent task (p = 0.01), indicating a greater dual-task cost of balance for the patients than controls (53% vs 28%, p = 0.04).</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">We suggest that tasks exploring executive functions involved in discriminating conflicting stimuli may be the most suitable to unmask the cognitive-postural interference phenomenon in patients with MS. This may support the hypothesis that MS-related damage constrains brain networks to subserve both postural control and executive functions.</AbstractText><CopyrightInformation>© 2016 American Academy of Neurology.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Prosperini</LastName><ForeName>Luca</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy. luca.prosperini@uniroma1.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Castelli</LastName><ForeName>Letizia</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>De Luca</LastName><ForeName>Francesca</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fabiano</LastName><ForeName>Francesca</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ferrante</LastName><ForeName>Ilaria</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>De Giglio</LastName><ForeName>Laura</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>From the Department of Neurology and Psychiatry, Sapienza University, Rome, Italy.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>08</Month><Day>12</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Neurology</MedlineTA><NlmUniqueID>0401060</NlmUniqueID><ISSNLinking>0028-3878</ISSNLinking></MedlineJournalInfo><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Neurology. 2016 Sep 13;87(11):1090</RefSource><PMID Version="1">27521433</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D001288" MajorTopicYN="N">Attention</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003071" MajorTopicYN="Y">Cognition</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003430" MajorTopicYN="N">Cross-Sectional Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D056344" MajorTopicYN="N">Executive Function</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009043" MajorTopicYN="Y">Motor Activity</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009103" MajorTopicYN="N">Multiple Sclerosis</DescriptorName><QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName><QualifierName UI="Q000523" MajorTopicYN="Y">psychology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009483" MajorTopicYN="N">Neuropsychological Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004856" MajorTopicYN="Y">Postural Balance</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015203" MajorTopicYN="N">Reproducibility of Results</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>12</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2016</Year><Month>04</Month><Day>06</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>8</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>8</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>6</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27521436</ArticleId><ArticleId IdType="pii">WNL.0000000000003090</ArticleId><ArticleId IdType="doi">10.1212/WNL.0000000000003090</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PosturoV1/Data/Main/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000633 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Corpus/biblio.hfd -nk 000633 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= PosturoV1
|flux= Main
|étape= Corpus
|type= RBID
|clé= pubmed:27521436
|texte= Task-dependent deterioration of balance underpinning cognitive-postural interference in MS.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Corpus/RBID.i -Sk "pubmed:27521436" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a PosturoV1
| This area was generated with Dilib version V0.6.37. |  |