The Sensor Technology and Rehabilitative Timing (START) Protocol: A Randomized Controlled Trial for the Rehabilitation of Mild Traumatic Brain Injury.
Identifieur interne : 000126 ( Main/Corpus ); précédent : 000125; suivant : 000127The Sensor Technology and Rehabilitative Timing (START) Protocol: A Randomized Controlled Trial for the Rehabilitation of Mild Traumatic Brain Injury.
Auteurs : Lucy Parrington ; Deborah A. Jehu ; Peter C. Fino ; Samuel Stuart ; Jennifer Wilhelm ; Natalie Pettigrew ; Charles F. Murchison ; Mahmoud El-Gohary ; Jess Vanderwalker ; Sean Pearson ; Timothy Hullar ; James C. Chesnutt ; Robert J. Peterka ; Fay B. Horak ; Laurie A. KingSource :
- Physical therapy [ 1538-6724 ] ; 2020.
English descriptors
- KwdEn :
- Adult (MeSH), Ambulatory Care (methods), Brain Concussion (rehabilitation), Exercise Therapy (methods), Home Care Services (MeSH), Humans (MeSH), Middle Aged (MeSH), Outcome Assessment, Health Care (MeSH), Randomized Controlled Trials as Topic (MeSH), Sample Size (MeSH), Time Factors (MeSH), Treatment Outcome (MeSH), Wearable Electronic Devices (MeSH).
- MESH :
Abstract
BACKGROUND
Clinical practice for rehabilitation after mild traumatic brain injury (mTBI) is variable, and guidance on when to initiate physical therapy is lacking. Wearable sensor technology may aid clinical assessment, performance monitoring, and exercise adherence, potentially improving rehabilitation outcomes during unsupervised home exercise programs.
OBJECTIVE
The objectives of this study were to: (1) determine whether initiating rehabilitation earlier than typical will improve outcomes after mTBI, and (2) examine whether using wearable sensors during a home-exercise program will improve outcomes in participants with mTBI.
DESIGN
This was a randomized controlled trial.
SETTING
This study will take place within an academic hospital setting at Oregon Health & Science University and Veterans Affairs Portland Health Care System, and in the home environment.
PARTICIPANTS
This study will include 160 individuals with mTBI.
INTERVENTION
The early intervention group (n = 80) will receive one-on-one physical therapy 8 times over 6 weeks and complete daily home exercises. The standard care group (n = 80) will complete the same intervention after a 6- to 8-week wait period. One-half of each group will receive wearable sensors for therapist monitoring of patient adherence and quality of movements during their home exercise program.
MEASUREMENTS
The primary outcome measure will be the Dizziness Handicap Inventory score. Secondary outcome measures will include symptomatology, static and dynamic postural control, central sensorimotor integration posturography, and vestibular-ocular-motor function.
LIMITATIONS
Potential limitations include variable onset of care, a wide range of ages, possible low adherence and/or withdrawal from the study in the standard of care group, and low Dizziness Handicap Inventory scores effecting ceiling for change after rehabilitation.
CONCLUSIONS
If initiating rehabilitation earlier improves primary and secondary outcomes post-mTBI, this could help shape current clinical care guidelines for rehabilitation. Additionally, using wearable sensors to monitor performance and adherence may improve home exercise outcomes.
DOI: 10.1093/ptj/pzaa007
PubMed: 31951263
Links to Exploration step
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Jehu</name><affiliation><nlm:affiliation>Department of Neurology, Oregon Health & Science University; Djavad Mowafaghian Centre for Brain Health, Centre for Hip Health and Mobility, and Department of Physical Therapy, University of British Columbia, Vancouver, British Columbia, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Fino, Peter C" sort="Fino, Peter C" uniqKey="Fino P" first="Peter C" last="Fino">Peter C. 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Chesnutt</name><affiliation><nlm:affiliation>Departments of Family Medicine, Neurology, and Orthopedics & Rehabilitation, Oregon Health & Science University.</nlm:affiliation></affiliation></author><author><name sortKey="Peterka, Robert J" sort="Peterka, Robert J" uniqKey="Peterka R" first="Robert J" last="Peterka">Robert J. Peterka</name><affiliation><nlm:affiliation>National Center for Rehabilitative Auditory Research, Veterans Affairs Portland Health Care System.</nlm:affiliation></affiliation></author><author><name sortKey="Horak, Fay B" sort="Horak, Fay B" uniqKey="Horak F" first="Fay B" last="Horak">Fay B. Horak</name><affiliation><nlm:affiliation>Department of Neurology, Oregon Health & Science University; Veterans Affairs Portland Health Care System; and APDM Inc.</nlm:affiliation></affiliation></author><author><name sortKey="King, Laurie A" sort="King, Laurie A" uniqKey="King L" first="Laurie A" last="King">Laurie A. King</name><affiliation><nlm:affiliation>Department of Neurology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239 (USA); Veterans Affairs Portland Health Care System; and National Center for Rehabilitative Auditory Research, Veterans Affairs Portland Health Care System.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:31951263</idno><idno type="pmid">31951263</idno><idno type="doi">10.1093/ptj/pzaa007</idno><idno type="wicri:Area/Main/Corpus">000126</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000126</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">The Sensor Technology and Rehabilitative Timing (START) Protocol: A Randomized Controlled Trial for the Rehabilitation of Mild Traumatic Brain Injury.</title><author><name sortKey="Parrington, Lucy" sort="Parrington, Lucy" uniqKey="Parrington L" first="Lucy" last="Parrington">Lucy Parrington</name><affiliation><nlm:affiliation>Department of Neurology, Oregon Health & Science University, Portland, Oregon; and Veterans Affairs Portland Health Care System, Portland, Oregon.</nlm:affiliation></affiliation></author><author><name sortKey="Jehu, Deborah A" sort="Jehu, Deborah A" uniqKey="Jehu D" first="Deborah A" last="Jehu">Deborah A. Jehu</name><affiliation><nlm:affiliation>Department of Neurology, Oregon Health & Science University; Djavad Mowafaghian Centre for Brain Health, Centre for Hip Health and Mobility, and Department of Physical Therapy, University of British Columbia, Vancouver, British Columbia, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Fino, Peter C" sort="Fino, Peter C" uniqKey="Fino P" first="Peter C" last="Fino">Peter C. Fino</name><affiliation><nlm:affiliation>Department of Neurology, Oregon Health & Science University; Veterans Affairs Portland Health Care System; and Department of Health, Kinesiology, and Recreation, University of Utah, Salt Lake City, Utah.</nlm:affiliation></affiliation></author><author><name sortKey="Stuart, Samuel" sort="Stuart, Samuel" uniqKey="Stuart S" first="Samuel" last="Stuart">Samuel Stuart</name><affiliation><nlm:affiliation>Department of Neurology, Oregon Health & Science University; and Department of Sport, Exercise and Rehabilitation, Northumbria University, Newcastle upon Tyne, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Wilhelm, Jennifer" sort="Wilhelm, Jennifer" uniqKey="Wilhelm J" first="Jennifer" last="Wilhelm">Jennifer Wilhelm</name><affiliation><nlm:affiliation>Department of Neurology, Oregon Health & Science University.</nlm:affiliation></affiliation></author><author><name sortKey="Pettigrew, Natalie" sort="Pettigrew, Natalie" uniqKey="Pettigrew N" first="Natalie" last="Pettigrew">Natalie Pettigrew</name><affiliation><nlm:affiliation>Department of Neurology, Oregon Health & Science University.</nlm:affiliation></affiliation></author><author><name sortKey="Murchison, Charles F" sort="Murchison, Charles F" uniqKey="Murchison C" first="Charles F" last="Murchison">Charles F. Murchison</name><affiliation><nlm:affiliation>Department of Neurology, Oregon Health & Science University; and Department of Biostatistics at the University of Alabama, Birmingham, Alabama.</nlm:affiliation></affiliation></author><author><name sortKey="El Gohary, Mahmoud" sort="El Gohary, Mahmoud" uniqKey="El Gohary M" first="Mahmoud" last="El-Gohary">Mahmoud El-Gohary</name><affiliation><nlm:affiliation>ADPM Inc, Portland, Oregon.</nlm:affiliation></affiliation></author><author><name sortKey="Vanderwalker, Jess" sort="Vanderwalker, Jess" uniqKey="Vanderwalker J" first="Jess" last="Vanderwalker">Jess Vanderwalker</name><affiliation><nlm:affiliation>ADPM Inc.</nlm:affiliation></affiliation></author><author><name sortKey="Pearson, Sean" sort="Pearson, Sean" uniqKey="Pearson S" first="Sean" last="Pearson">Sean Pearson</name><affiliation><nlm:affiliation>ADPM Inc.</nlm:affiliation></affiliation></author><author><name sortKey="Hullar, Timothy" sort="Hullar, Timothy" uniqKey="Hullar T" first="Timothy" last="Hullar">Timothy Hullar</name><affiliation><nlm:affiliation>Department of Otolaryngology-Head and Neck Surgery, Oregon Health & Science University.</nlm:affiliation></affiliation></author><author><name sortKey="Chesnutt, James C" sort="Chesnutt, James C" uniqKey="Chesnutt J" first="James C" last="Chesnutt">James C. Chesnutt</name><affiliation><nlm:affiliation>Departments of Family Medicine, Neurology, and Orthopedics & Rehabilitation, Oregon Health & Science University.</nlm:affiliation></affiliation></author><author><name sortKey="Peterka, Robert J" sort="Peterka, Robert J" uniqKey="Peterka R" first="Robert J" last="Peterka">Robert J. Peterka</name><affiliation><nlm:affiliation>National Center for Rehabilitative Auditory Research, Veterans Affairs Portland Health Care System.</nlm:affiliation></affiliation></author><author><name sortKey="Horak, Fay B" sort="Horak, Fay B" uniqKey="Horak F" first="Fay B" last="Horak">Fay B. Horak</name><affiliation><nlm:affiliation>Department of Neurology, Oregon Health & Science University; Veterans Affairs Portland Health Care System; and APDM Inc.</nlm:affiliation></affiliation></author><author><name sortKey="King, Laurie A" sort="King, Laurie A" uniqKey="King L" first="Laurie A" last="King">Laurie A. King</name><affiliation><nlm:affiliation>Department of Neurology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239 (USA); Veterans Affairs Portland Health Care System; and National Center for Rehabilitative Auditory Research, Veterans Affairs Portland Health Care System.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Physical therapy</title><idno type="eISSN">1538-6724</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term><term>Ambulatory Care (methods)</term><term>Brain Concussion (rehabilitation)</term><term>Exercise Therapy (methods)</term><term>Home Care Services (MeSH)</term><term>Humans (MeSH)</term><term>Middle Aged (MeSH)</term><term>Outcome Assessment, Health Care (MeSH)</term><term>Randomized Controlled Trials as Topic (MeSH)</term><term>Sample Size (MeSH)</term><term>Time Factors (MeSH)</term><term>Treatment Outcome (MeSH)</term><term>Wearable Electronic Devices (MeSH)</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Ambulatory Care</term><term>Exercise Therapy</term></keywords><keywords scheme="MESH" qualifier="rehabilitation" xml:lang="en"><term>Brain Concussion</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Home Care Services</term><term>Humans</term><term>Middle Aged</term><term>Outcome Assessment, Health Care</term><term>Randomized Controlled Trials as Topic</term><term>Sample Size</term><term>Time Factors</term><term>Treatment Outcome</term><term>Wearable Electronic Devices</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>Clinical practice for rehabilitation after mild traumatic brain injury (mTBI) is variable, and guidance on when to initiate physical therapy is lacking. Wearable sensor technology may aid clinical assessment, performance monitoring, and exercise adherence, potentially improving rehabilitation outcomes during unsupervised home exercise programs.</p></div><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b></p><p>The objectives of this study were to: (1) determine whether initiating rehabilitation earlier than typical will improve outcomes after mTBI, and (2) examine whether using wearable sensors during a home-exercise program will improve outcomes in participants with mTBI.</p></div><div type="abstract" xml:lang="en"><p><b>DESIGN</b></p><p>This was a randomized controlled trial.</p></div><div type="abstract" xml:lang="en"><p><b>SETTING</b></p><p>This study will take place within an academic hospital setting at Oregon Health & Science University and Veterans Affairs Portland Health Care System, and in the home environment.</p></div><div type="abstract" xml:lang="en"><p><b>PARTICIPANTS</b></p><p>This study will include 160 individuals with mTBI.</p></div><div type="abstract" xml:lang="en"><p><b>INTERVENTION</b></p><p>The early intervention group (n = 80) will receive one-on-one physical therapy 8 times over 6 weeks and complete daily home exercises. The standard care group (n = 80) will complete the same intervention after a 6- to 8-week wait period. One-half of each group will receive wearable sensors for therapist monitoring of patient adherence and quality of movements during their home exercise program.</p></div><div type="abstract" xml:lang="en"><p><b>MEASUREMENTS</b></p><p>The primary outcome measure will be the Dizziness Handicap Inventory score. Secondary outcome measures will include symptomatology, static and dynamic postural control, central sensorimotor integration posturography, and vestibular-ocular-motor function.</p></div><div type="abstract" xml:lang="en"><p><b>LIMITATIONS</b></p><p>Potential limitations include variable onset of care, a wide range of ages, possible low adherence and/or withdrawal from the study in the standard of care group, and low Dizziness Handicap Inventory scores effecting ceiling for change after rehabilitation.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>If initiating rehabilitation earlier improves primary and secondary outcomes post-mTBI, this could help shape current clinical care guidelines for rehabilitation. Additionally, using wearable sensors to monitor performance and adherence may improve home exercise outcomes.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">31951263</PMID><DateCompleted><Year>2020</Year><Month>07</Month><Day>03</Day></DateCompleted><DateRevised><Year>2020</Year><Month>07</Month><Day>03</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1538-6724</ISSN><JournalIssue CitedMedium="Internet"><Volume>100</Volume><Issue>4</Issue><PubDate><Year>2020</Year><Month>04</Month><Day>17</Day></PubDate></JournalIssue><Title>Physical therapy</Title><ISOAbbreviation>Phys Ther</ISOAbbreviation></Journal><ArticleTitle>The Sensor Technology and Rehabilitative Timing (START) Protocol: A Randomized Controlled Trial for the Rehabilitation of Mild Traumatic Brain Injury.</ArticleTitle><Pagination><MedlinePgn>687-697</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1093/ptj/pzaa007</ELocationID><Abstract><AbstractText Label="BACKGROUND">Clinical practice for rehabilitation after mild traumatic brain injury (mTBI) is variable, and guidance on when to initiate physical therapy is lacking. Wearable sensor technology may aid clinical assessment, performance monitoring, and exercise adherence, potentially improving rehabilitation outcomes during unsupervised home exercise programs.</AbstractText><AbstractText Label="OBJECTIVE">The objectives of this study were to: (1) determine whether initiating rehabilitation earlier than typical will improve outcomes after mTBI, and (2) examine whether using wearable sensors during a home-exercise program will improve outcomes in participants with mTBI.</AbstractText><AbstractText Label="DESIGN">This was a randomized controlled trial.</AbstractText><AbstractText Label="SETTING">This study will take place within an academic hospital setting at Oregon Health & Science University and Veterans Affairs Portland Health Care System, and in the home environment.</AbstractText><AbstractText Label="PARTICIPANTS">This study will include 160 individuals with mTBI.</AbstractText><AbstractText Label="INTERVENTION">The early intervention group (n = 80) will receive one-on-one physical therapy 8 times over 6 weeks and complete daily home exercises. The standard care group (n = 80) will complete the same intervention after a 6- to 8-week wait period. One-half of each group will receive wearable sensors for therapist monitoring of patient adherence and quality of movements during their home exercise program.</AbstractText><AbstractText Label="MEASUREMENTS">The primary outcome measure will be the Dizziness Handicap Inventory score. Secondary outcome measures will include symptomatology, static and dynamic postural control, central sensorimotor integration posturography, and vestibular-ocular-motor function.</AbstractText><AbstractText Label="LIMITATIONS">Potential limitations include variable onset of care, a wide range of ages, possible low adherence and/or withdrawal from the study in the standard of care group, and low Dizziness Handicap Inventory scores effecting ceiling for change after rehabilitation.</AbstractText><AbstractText Label="CONCLUSIONS">If initiating rehabilitation earlier improves primary and secondary outcomes post-mTBI, this could help shape current clinical care guidelines for rehabilitation. Additionally, using wearable sensors to monitor performance and adherence may improve home exercise outcomes.</AbstractText><CopyrightInformation>© 2020 American Physical Therapy Association.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Parrington</LastName><ForeName>Lucy</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Neurology, Oregon Health & Science University, Portland, Oregon; and Veterans Affairs Portland Health Care System, Portland, Oregon.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jehu</LastName><ForeName>Deborah A</ForeName><Initials>DA</Initials><AffiliationInfo><Affiliation>Department of Neurology, Oregon Health & Science University; Djavad Mowafaghian Centre for Brain Health, Centre for Hip Health and Mobility, and Department of Physical Therapy, University of British Columbia, Vancouver, British Columbia, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fino</LastName><ForeName>Peter C</ForeName><Initials>PC</Initials><AffiliationInfo><Affiliation>Department of Neurology, Oregon Health & Science University; Veterans Affairs Portland Health Care System; and Department of Health, Kinesiology, and Recreation, University of Utah, Salt Lake City, Utah.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stuart</LastName><ForeName>Samuel</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Neurology, Oregon Health & Science University; and Department of Sport, Exercise and Rehabilitation, Northumbria University, Newcastle upon Tyne, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wilhelm</LastName><ForeName>Jennifer</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Neurology, Oregon Health & Science University.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pettigrew</LastName><ForeName>Natalie</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Neurology, Oregon Health & Science University.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Murchison</LastName><ForeName>Charles F</ForeName><Initials>CF</Initials><AffiliationInfo><Affiliation>Department of Neurology, Oregon Health & Science University; and Department of Biostatistics at the University of Alabama, Birmingham, Alabama.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>El-Gohary</LastName><ForeName>Mahmoud</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>ADPM Inc, Portland, Oregon.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>VanDerwalker</LastName><ForeName>Jess</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>ADPM Inc.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pearson</LastName><ForeName>Sean</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>ADPM Inc.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hullar</LastName><ForeName>Timothy</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Otolaryngology-Head and Neck Surgery, Oregon Health & Science University.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chesnutt</LastName><ForeName>James C</ForeName><Initials>JC</Initials><AffiliationInfo><Affiliation>Departments of Family Medicine, Neurology, and Orthopedics & Rehabilitation, Oregon Health & Science University.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Peterka</LastName><ForeName>Robert J</ForeName><Initials>RJ</Initials><AffiliationInfo><Affiliation>National Center for Rehabilitative Auditory Research, Veterans Affairs Portland Health Care System.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Horak</LastName><ForeName>Fay B</ForeName><Initials>FB</Initials><AffiliationInfo><Affiliation>Department of Neurology, Oregon Health & Science University; Veterans Affairs Portland Health Care System; and APDM Inc.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>King</LastName><ForeName>Laurie A</ForeName><Initials>LA</Initials><AffiliationInfo><Affiliation>Department of Neurology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239 (USA); Veterans Affairs Portland Health Care System; and National Center for Rehabilitative Auditory Research, Veterans Affairs Portland Health Care System.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><DataBankList CompleteYN="Y"><DataBank><DataBankName>ClinicalTrials.gov</DataBankName><AccessionNumberList><AccessionNumber>NCT03479541</AccessionNumber></AccessionNumberList></DataBank></DataBankList><GrantList CompleteYN="Y"><Grant><GrantID>T32 DK091317</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D000078325">Clinical Trial Protocol</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013486">Research Support, U.S. Gov't, Non-P.H.S.</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Phys Ther</MedlineTA><NlmUniqueID>0022623</NlmUniqueID><ISSNLinking>0031-9023</ISSNLinking></MedlineJournalInfo><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000553" MajorTopicYN="N">Ambulatory Care</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001924" MajorTopicYN="N">Brain Concussion</DescriptorName><QualifierName UI="Q000534" MajorTopicYN="Y">rehabilitation</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005081" MajorTopicYN="N">Exercise Therapy</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006699" MajorTopicYN="Y">Home Care Services</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017063" MajorTopicYN="N">Outcome Assessment, Health Care</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016032" MajorTopicYN="Y">Randomized Controlled Trials as Topic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018401" MajorTopicYN="N">Sample Size</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000076251" MajorTopicYN="Y">Wearable Electronic Devices</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>01</Month><Day>17</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2018</Year><Month>11</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2019</Year><Month>10</Month><Day>04</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>1</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>7</Month><Day>4</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>1</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">31951263</ArticleId><ArticleId IdType="pii">5707558</ArticleId><ArticleId IdType="doi">10.1093/ptj/pzaa007</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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