The balance of biogenic amines as condition for normal behaviour
Identifieur interne : 002C95 ( Main/Exploration ); précédent : 002C94; suivant : 002C96The balance of biogenic amines as condition for normal behaviour
Auteurs : W. Birkmayer [Autriche] ; W. Danielczyk [Autriche] ; E. Neumayer [Autriche] ; P. Riederer [Autriche]Source :
- Journal of Neural Transmission [ 0300-9564 ] ; 1972-06-01.
Abstract
Summary: An accumulation of norepinephrin, serotonin and dopamin exists in the brainstem. A decrease of biogenic amines in the brains of Parkinson's cases has been demonstrated. A substitution by the precursor L-DOPA produces an increase of dopamin in the brain and a decrease of serotonin. The high level of dopamin improves the akinesia and the depletion of serotonin causes a toxic delir. A substitution by l-tryptophan restores the balance and the Dopa-psychosis disappears.
Url:
DOI: 10.1007/BF01260902
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Birkmayer</name><affiliation wicri:level="1"><country xml:lang="fr">Autriche</country><wicri:regionArea>Ludwig-Boltzmann-Institut für Neurochemie und neurologische Abteilung des Alterskrankenhauses der Stadt Wien-Lainz</wicri:regionArea></affiliation></author><author><name sortKey="Danielczyk, W" sort="Danielczyk, W" uniqKey="Danielczyk W" first="W." last="Danielczyk">W. Danielczyk</name><affiliation wicri:level="1"><country xml:lang="fr">Autriche</country><wicri:regionArea>Ludwig-Boltzmann-Institut für Neurochemie und neurologische Abteilung des Alterskrankenhauses der Stadt Wien-Lainz</wicri:regionArea></affiliation></author><author><name sortKey="Neumayer, E" sort="Neumayer, E" uniqKey="Neumayer E" first="E." last="Neumayer">E. Neumayer</name><affiliation wicri:level="1"><country xml:lang="fr">Autriche</country><wicri:regionArea>Ludwig-Boltzmann-Institut für Neurochemie und neurologische Abteilung des Alterskrankenhauses der Stadt Wien-Lainz</wicri:regionArea></affiliation></author><author><name sortKey="Riederer, P" sort="Riederer, P" uniqKey="Riederer P" first="P." last="Riederer">P. Riederer</name><affiliation wicri:level="1"><country xml:lang="fr">Autriche</country><wicri:regionArea>Ludwig-Boltzmann-Institut für Neurochemie und neurologische Abteilung des Alterskrankenhauses der Stadt Wien-Lainz</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Neural Transmission</title><title level="j" type="sub">Basic neurosciences and genetics, Parkinson's disease and allied conditions, Alzheimer's disease and related disorders, biological psychiatry</title><title level="j" type="abbrev">J. Neural Transmission</title><idno type="ISSN">0300-9564</idno><idno type="eISSN">1435-1463</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Vienna</pubPlace><date type="published" when="1972-06-01">1972-06-01</date><biblScope unit="volume">33</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="163">163</biblScope><biblScope unit="page" to="178">178</biblScope></imprint><idno type="ISSN">0300-9564</idno></series><idno type="istex">F377EC34708C70F8E98E7629BE5B9D6A6312579D</idno><idno type="DOI">10.1007/BF01260902</idno><idno type="ArticleID">Art5</idno><idno type="ArticleID">BF01260902</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0300-9564</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Summary: An accumulation of norepinephrin, serotonin and dopamin exists in the brainstem. A decrease of biogenic amines in the brains of Parkinson's cases has been demonstrated. A substitution by the precursor L-DOPA produces an increase of dopamin in the brain and a decrease of serotonin. The high level of dopamin improves the akinesia and the depletion of serotonin causes a toxic delir. A substitution by l-tryptophan restores the balance and the Dopa-psychosis disappears.</div></front></TEI><affiliations><list><country><li>Autriche</li></country></list><tree><country name="Autriche"><noRegion><name sortKey="Birkmayer, W" sort="Birkmayer, W" uniqKey="Birkmayer W" first="W." last="Birkmayer">W. Birkmayer</name></noRegion><name sortKey="Danielczyk, W" sort="Danielczyk, W" uniqKey="Danielczyk W" first="W." last="Danielczyk">W. Danielczyk</name><name sortKey="Neumayer, E" sort="Neumayer, E" uniqKey="Neumayer E" first="E." last="Neumayer">E. Neumayer</name><name sortKey="Riederer, P" sort="Riederer, P" uniqKey="Riederer P" first="P." last="Riederer">P. 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