ParkinsonV1, Main, Exploration, bibRecord, 002171

Human aging brain disorders: Role of antioxidant enzymes

Identifieur interne : 002171 ( Main/Exploration ); précédent : 002170; suivant : 002172

Human aging brain disorders: Role of antioxidant enzymes

Auteurs : Ma Rosario De La Torre [Espagne] ; Angela Casado [Espagne] ; Encarnaci N L Pez-Fernández [Espagne] ; Diana Carrascosa [Espagne] ; Concepci N Casado [Espagne] ; Domenico Venarucci [Italie] ; Vincenzo Venarucci [Italie]

Source :

Neurochemical Research [ 0364-3190 ] ; 1996-08-01.

RBID : ISTEX:4AB7038D70C78C4CD7AFFA7B54A302040A349E86

Abstract

Abstract: In order to investigate the role of two free radical detoxificant enzymes in patients with aging brain disorders, superoxide dismutase (SOD) and catalase (CAT) activities have been measured in blood from male and female human patients of different ages with several types of aging brain disorders. When compared with activities in the normal population, we have detected: 1) SOD and CAT activities are decreased in patients with Parkinson disease. 2) SOD activity seems to be normal and CAT activity is decreased in patients with dementia. 3) In the patients with stroke, SOD activity is normal, while CAT activity is decreased. SOD activity was measured in red blood cells using the Minami and Yoshikawa method. CAT activity was measured in hemolysates by the method of Aebi. We can conclude that SOD and CAT activities in patients with Parkinson disease are decreased.

Url:

https://api.istex.fr/document/4AB7038D70C78C4CD7AFFA7B54A302040A349E86/fulltext/pdf

DOI: 10.1007/BF02532336

Affiliations:

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Le document en format XML

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<front><div type="abstract" xml:lang="en">Abstract: In order to investigate the role of two free radical detoxificant enzymes in patients with aging brain disorders, superoxide dismutase (SOD) and catalase (CAT) activities have been measured in blood from male and female human patients of different ages with several types of aging brain disorders. When compared with activities in the normal population, we have detected: 1) SOD and CAT activities are decreased in patients with Parkinson disease. 2) SOD activity seems to be normal and CAT activity is decreased in patients with dementia. 3) In the patients with stroke, SOD activity is normal, while CAT activity is decreased. SOD activity was measured in red blood cells using the Minami and Yoshikawa method. CAT activity was measured in hemolysates by the method of Aebi. We can conclude that SOD and CAT activities in patients with Parkinson disease are decreased.</div>
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Human aging brain disorders: Role of antioxidant enzymes

Human aging brain disorders: Role of antioxidant enzymes

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Abstract

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