Serotonin and emotion, learning and memory
Identifieur interne : 000053 ( Main/Exploration ); précédent : 000052; suivant : 000054Serotonin and emotion, learning and memory
Auteurs : Alfredo Meneses [Mexique] ; Gustavo Liy-SalmeronSource :
- Reviews in the Neurosciences [ 0334-1763 ] ; 2012-11-01.
Abstract
Serotonin (5-hydroxytryptamien, 5-HT) has been linked to emotional and motivational aspects of human behavior, including anxiety, depression, impulsivity, etc. Several clinically effective drugs exert effects via 5-HT systems. Growing evidence suggests that those effects play an important role in learning and memory. Whether the role of serotonin is related to memory and/or behavioral or emotional aspects remains an important question. A key question that remains is whether 5-HT markers (e.g., receptors) directly or indirectly participate and/or contribute to the physiological and pharmacological basis of memory and its pathogenesis. The major aim of this paper is to re-examine some recent advances regarding mammalian 5-HT receptors and transporter in light of their physiological, pathophysiological and therapeutic implications for memory. We particularly address evidence involving 5-HT systems in behavioral, pharmacological, molecular, genetic and imaging results and memory. Finally, this paper aims to summarize a portion of the evidence about serotonin, memory and emotion from animal and human studies and provide an overview of potential tools, markers and cellular and molecular candidate mechanisms. It should be noted that there are several subjects that this paper only briefly touches upon, presenting only what may be the most salient findings in the context of memory, emotion and serotonin.
Url:
DOI: 10.1515/revneuro-2012-0060
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Serotonin and emotion, learning and memory</title><author><name sortKey="Meneses, Alfredo" sort="Meneses, Alfredo" uniqKey="Meneses A" first="Alfredo" last="Meneses">Alfredo Meneses</name></author><author><name sortKey="Liy Salmeron, Gustavo" sort="Liy Salmeron, Gustavo" uniqKey="Liy Salmeron G" first="Gustavo" last="Liy-Salmeron">Gustavo Liy-Salmeron</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:5975BDDE7FEFE2161E850839B3256082817814B8</idno><date when="2012" year="2012">2012</date><idno type="doi">10.1515/revneuro-2012-0060</idno><idno type="url">https://api.istex.fr/document/5975BDDE7FEFE2161E850839B3256082817814B8/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">002E53</idno><idno type="wicri:Area/Main/Curation">002A70</idno><idno type="wicri:Area/Main/Exploration">000053</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Serotonin and emotion, learning and memory</title><author><name sortKey="Meneses, Alfredo" sort="Meneses, Alfredo" uniqKey="Meneses A" first="Alfredo" last="Meneses">Alfredo Meneses</name><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">Mexique</country><wicri:regionArea>Departamento de Farmacobiología, CINVESTAV-IPN, Tenorios 235, 14330 Granjas Coapa</wicri:regionArea><wicri:noRegion>14330 Granjas Coapa</wicri:noRegion></affiliation></author><author><name sortKey="Liy Salmeron, Gustavo" sort="Liy Salmeron, Gustavo" uniqKey="Liy Salmeron G" first="Gustavo" last="Liy-Salmeron">Gustavo Liy-Salmeron</name><affiliation><wicri:noCountry code="subField">Huixquilucan Edo. de México</wicri:noCountry></affiliation></author></analytic><monogr></monogr><series><title level="j">Reviews in the Neurosciences</title><idno type="ISSN">0334-1763</idno><idno type="eISSN">2191-0200</idno><imprint><publisher>De Gruyter</publisher><date type="published" when="2012-11-01">2012-11-01</date><biblScope unit="volume">23</biblScope><biblScope unit="issue">5-6</biblScope><biblScope unit="page" from="543">543</biblScope><biblScope unit="page" to="553">553</biblScope></imprint><idno type="ISSN">0334-1763</idno></series><idno type="istex">5975BDDE7FEFE2161E850839B3256082817814B8</idno><idno type="DOI">10.1515/revneuro-2012-0060</idno><idno type="ArticleID">revneuro-2012-0060</idno><idno type="Related-article-Href">revneuro-2012-0060.pdf</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0334-1763</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Serotonin (5-hydroxytryptamien, 5-HT) has been linked to emotional and motivational aspects of human behavior, including anxiety, depression, impulsivity, etc. Several clinically effective drugs exert effects via 5-HT systems. Growing evidence suggests that those effects play an important role in learning and memory. Whether the role of serotonin is related to memory and/or behavioral or emotional aspects remains an important question. A key question that remains is whether 5-HT markers (e.g., receptors) directly or indirectly participate and/or contribute to the physiological and pharmacological basis of memory and its pathogenesis. The major aim of this paper is to re-examine some recent advances regarding mammalian 5-HT receptors and transporter in light of their physiological, pathophysiological and therapeutic implications for memory. We particularly address evidence involving 5-HT systems in behavioral, pharmacological, molecular, genetic and imaging results and memory. Finally, this paper aims to summarize a portion of the evidence about serotonin, memory and emotion from animal and human studies and provide an overview of potential tools, markers and cellular and molecular candidate mechanisms. It should be noted that there are several subjects that this paper only briefly touches upon, presenting only what may be the most salient findings in the context of memory, emotion and serotonin.</div></front></TEI><affiliations><list><country><li>Mexique</li></country></list><tree><noCountry><name sortKey="Liy Salmeron, Gustavo" sort="Liy Salmeron, Gustavo" uniqKey="Liy Salmeron G" first="Gustavo" last="Liy-Salmeron">Gustavo Liy-Salmeron</name></noCountry><country name="Mexique"><noRegion><name sortKey="Meneses, Alfredo" sort="Meneses, Alfredo" uniqKey="Meneses A" first="Alfredo" last="Meneses">Alfredo Meneses</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000053 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000053 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:5975BDDE7FEFE2161E850839B3256082817814B8
|texte= Serotonin and emotion, learning and memory
}}
| This area was generated with Dilib version V0.6.23. |  |