Nucleus ruber and L-Dopa psychosis: Biochemical post-mortem findings
Identifieur interne : 002812 ( Main/Curation ); précédent : 002811; suivant : 002813Nucleus ruber and L-Dopa psychosis: Biochemical post-mortem findings
Auteurs : W. Birkmayer [Autriche] ; W. Danielczyk [Autriche] ; E. Neumayer [Autriche] ; P. Riederer [Autriche]Source :
- Journal of Neural Transmission [ 0300-9564 ] ; 1974-06-01.
Abstract
Summary: 1. In various areas of the brainstem: nucleus caudatus, putamen, gyrus cinguli, oral and caudal part of substantia nigra, nucleus amygdalae, globus pallidus, raphe, and nucleus ruber L-tyrosine, dopamine, noradrenaline, L-tryptophan, serotonin and 5-hydroxyindoleacetic acid were investigated in eight cases of deceased L-Dopa psychosis, six cases of parkinsonian patients without psychotic symptoms, and in nine controls. 2. The values of L-tyrosine in all investigated areas were increased in parkinsonian patients as well as in L-Dopa psychosis. 3. The dopamine levels in all areas were decreased in both groups. 4. Noradrenaline shows moderate slight increase in six out of nine regions in the psychotic group, when compared to parkinsonian patients without psychotic symptoms. 5. L-tryptophan levels in the psychotic group are decreased in all areas, whereas levels in parkinsonian patients without psychotic symptoms are equal to those of the Controls. 6. The 5-hydroxytryptamine levels in the psychotic group are increased in eight of nine regions, when compared to parkinsonian patients without psychotic symptoms, predominantly in the nucleus ruber, somewhat less in the raphe, and in the globus pallidus. 7. 5-hydroxyindoleacetic acid levels show a similar pattern as 5-HT. 8. The loss of balance will be discussed as trigger of the psychotic symptoms.
Url:
DOI: 10.1007/BF01250738
Links toward previous steps (curation, corpus...)
- to stream Main, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002B79
Links to Exploration step
ISTEX:81958F09B170231555C94C424BF857BD1978794CLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Nucleus ruber and L-Dopa psychosis: Biochemical post-mortem findings</title><author><name sortKey="Birkmayer, W" sort="Birkmayer, W" uniqKey="Birkmayer W" first="W." last="Birkmayer">W. Birkmayer</name><affiliation wicri:level="1"><mods:affiliation>Ludwig-Boltzmann-Institut für Neurochemie, Vienna, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Ludwig-Boltzmann-Institut für Neurochemie, Vienna</wicri:regionArea></affiliation></author><author><name sortKey="Danielczyk, W" sort="Danielczyk, W" uniqKey="Danielczyk W" first="W." last="Danielczyk">W. Danielczyk</name><affiliation wicri:level="1"><mods:affiliation>Ludwig-Boltzmann-Institut für Neurochemie, Vienna, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Ludwig-Boltzmann-Institut für Neurochemie, Vienna</wicri:regionArea></affiliation></author><author><name sortKey="Neumayer, E" sort="Neumayer, E" uniqKey="Neumayer E" first="E." last="Neumayer">E. Neumayer</name><affiliation wicri:level="1"><mods:affiliation>Ludwig-Boltzmann-Institut für Neurochemie, Vienna, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Ludwig-Boltzmann-Institut für Neurochemie, Vienna</wicri:regionArea></affiliation></author><author><name sortKey="Riederer, P" sort="Riederer, P" uniqKey="Riederer P" first="P." last="Riederer">P. Riederer</name><affiliation wicri:level="1"><mods:affiliation>Ludwig-Boltzmann-Institut für Neurochemie, Vienna, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Ludwig-Boltzmann-Institut für Neurochemie, Vienna</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:81958F09B170231555C94C424BF857BD1978794C</idno><date when="1974" year="1974">1974</date><idno type="doi">10.1007/BF01250738</idno><idno type="url">https://api.istex.fr/document/81958F09B170231555C94C424BF857BD1978794C/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">002B79</idno><idno type="wicri:Area/Main/Curation">002812</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Nucleus ruber and L-Dopa psychosis: Biochemical post-mortem findings</title><author><name sortKey="Birkmayer, W" sort="Birkmayer, W" uniqKey="Birkmayer W" first="W." last="Birkmayer">W. Birkmayer</name><affiliation wicri:level="1"><mods:affiliation>Ludwig-Boltzmann-Institut für Neurochemie, Vienna, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Ludwig-Boltzmann-Institut für Neurochemie, Vienna</wicri:regionArea></affiliation></author><author><name sortKey="Danielczyk, W" sort="Danielczyk, W" uniqKey="Danielczyk W" first="W." last="Danielczyk">W. Danielczyk</name><affiliation wicri:level="1"><mods:affiliation>Ludwig-Boltzmann-Institut für Neurochemie, Vienna, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Ludwig-Boltzmann-Institut für Neurochemie, Vienna</wicri:regionArea></affiliation></author><author><name sortKey="Neumayer, E" sort="Neumayer, E" uniqKey="Neumayer E" first="E." last="Neumayer">E. Neumayer</name><affiliation wicri:level="1"><mods:affiliation>Ludwig-Boltzmann-Institut für Neurochemie, Vienna, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Ludwig-Boltzmann-Institut für Neurochemie, Vienna</wicri:regionArea></affiliation></author><author><name sortKey="Riederer, P" sort="Riederer, P" uniqKey="Riederer P" first="P." last="Riederer">P. Riederer</name><affiliation wicri:level="1"><mods:affiliation>Ludwig-Boltzmann-Institut für Neurochemie, Vienna, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Ludwig-Boltzmann-Institut für Neurochemie, Vienna</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Neural Transmission</title><title level="j" type="sub">Basic neurosciences and genetics, Parkinson's disease and allied conditions, Alzheimer's disease and related disorders, biological psychiatry</title><title level="j" type="abbrev">J. Neural Transmission</title><idno type="ISSN">0300-9564</idno><idno type="eISSN">1435-1463</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Vienna</pubPlace><date type="published" when="1974-06-01">1974-06-01</date><biblScope unit="volume">35</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="93">93</biblScope><biblScope unit="page" to="116">116</biblScope></imprint><idno type="ISSN">0300-9564</idno></series><idno type="istex">81958F09B170231555C94C424BF857BD1978794C</idno><idno type="DOI">10.1007/BF01250738</idno><idno type="ArticleID">Art1</idno><idno type="ArticleID">BF01250738</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0300-9564</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Summary: 1. In various areas of the brainstem: nucleus caudatus, putamen, gyrus cinguli, oral and caudal part of substantia nigra, nucleus amygdalae, globus pallidus, raphe, and nucleus ruber L-tyrosine, dopamine, noradrenaline, L-tryptophan, serotonin and 5-hydroxyindoleacetic acid were investigated in eight cases of deceased L-Dopa psychosis, six cases of parkinsonian patients without psychotic symptoms, and in nine controls. 2. The values of L-tyrosine in all investigated areas were increased in parkinsonian patients as well as in L-Dopa psychosis. 3. The dopamine levels in all areas were decreased in both groups. 4. Noradrenaline shows moderate slight increase in six out of nine regions in the psychotic group, when compared to parkinsonian patients without psychotic symptoms. 5. L-tryptophan levels in the psychotic group are decreased in all areas, whereas levels in parkinsonian patients without psychotic symptoms are equal to those of the Controls. 6. The 5-hydroxytryptamine levels in the psychotic group are increased in eight of nine regions, when compared to parkinsonian patients without psychotic symptoms, predominantly in the nucleus ruber, somewhat less in the raphe, and in the globus pallidus. 7. 5-hydroxyindoleacetic acid levels show a similar pattern as 5-HT. 8. The loss of balance will be discussed as trigger of the psychotic symptoms.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002812 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 002812 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonV1
|flux= Main
|étape= Curation
|type= RBID
|clé= ISTEX:81958F09B170231555C94C424BF857BD1978794C
|texte= Nucleus ruber and L-Dopa psychosis: Biochemical post-mortem findings
}}
| This area was generated with Dilib version V0.6.23. |  |