Patients’ expectations of deep brain stimulation, and subjective perceived outcome related to clinical measures in Parkinson's disease: a mixed-method approach
Identifieur interne : 001562 ( Main/Curation ); précédent : 001561; suivant : 001563Patients’ expectations of deep brain stimulation, and subjective perceived outcome related to clinical measures in Parkinson's disease: a mixed-method approach
Auteurs : Franziska Maier [Allemagne] ; Catharine J. Lewis [Allemagne] ; Nina Horstkoetter [Allemagne] ; Carsten Eggers [Allemagne] ; Elke Kalbe [Allemagne] ; Mohammad Maarouf [Allemagne] ; Jens Kuhn [Allemagne] ; Mateusz Zurowski [Canada] ; Elena Moro [France] ; Christiane Woopen [Allemagne] ; Lars Timmermann [Allemagne]Source :
- Journal of Neurology, Neurosurgery & Psychiatry [ 0022-3050 ] ; 2013-11.
Abstract
Objective To study patients’ expectations of subthalamic deep brain stimulation (STN-DBS) and their subjective perceived outcome, by using qualitative and quantitative methods in Parkinson's disease (PD). Methods PD patients were prospectively examined before and 3 months after surgery. Semistructured interviews regarding preoperative expectations and postsurgical subjective perceived outcome were conducted. These were analysed using content analysis. For statistical analyses, patients were classified according to their subjective perceived outcome, resulting in three different subjective outcome groups (negative, mixed, positive outcome). The groups were used for multiple comparisons between and within each group regarding motor impairment, quality of life (QoL), neuropsychiatric status and cognitive functioning, using standard instruments. A logistic regression analysis was conducted to find predictors of subjective negative outcome. Receiver operating characteristic curves were used to analyse cut-off scores for predictive tests. Results Of the 30 PD patients participating, 8 had a subjective negative outcome, 8 a mixed and 14 a positive outcome. All groups significantly improved in motor functioning. Patients with subjective negative outcome were characterised by preoperative unrealistic expectations, no postsurgical improvement in QoL, and significantly higher presurgical and postsurgical apathy and depression scores. Higher preoperative apathy and depression scores were significant predictors of negative subjective outcome. Cut-off scores for apathy and depression were identified. Conclusions The mixed-method approach proved useful in examining a patient's subjective perception of STN-DBS outcome. Our results show that significant motor improvement does not necessarily lead to a positive subjective outcome. Moreover, PD patients should be screened carefully before surgery regarding apathy and depression. (DRKS-ID: DRKS00003221).
Url:
DOI: 10.1136/jnnp-2012-303670
Links toward previous steps (curation, corpus...)
- to stream Main, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001805
Links to Exploration step
ISTEX:436610088435E9614BE05D633E7A803476F69355Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Patients’ expectations of deep brain stimulation, and subjective perceived outcome related to clinical measures in Parkinson's disease: a mixed-method approach</title><author><name sortKey="Maier, Franziska" sort="Maier, Franziska" uniqKey="Maier F" first="Franziska" last="Maier">Franziska Maier</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, University of Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Lewis, Catharine J" sort="Lewis, Catharine J" uniqKey="Lewis C" first="Catharine J" last="Lewis">Catharine J. Lewis</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, University of Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Horstkoetter, Nina" sort="Horstkoetter, Nina" uniqKey="Horstkoetter N" first="Nina" last="Horstkoetter">Nina Horstkoetter</name><affiliation wicri:level="1"><mods:affiliation>Research Unit Ethics, Institute for the History of Medicine and Medical Ethics, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit Ethics, Institute for the History of Medicine and Medical Ethics, University of Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Eggers, Carsten" sort="Eggers, Carsten" uniqKey="Eggers C" first="Carsten" last="Eggers">Carsten Eggers</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, University of Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Kalbe, Elke" sort="Kalbe, Elke" uniqKey="Kalbe E" first="Elke" last="Kalbe">Elke Kalbe</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, University of Cologne, Cologne</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Institute for Gerontology, University of Vechta, Vechta, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Gerontology, University of Vechta, Vechta</wicri:regionArea></affiliation></author><author><name sortKey="Maarouf, Mohammad" sort="Maarouf, Mohammad" uniqKey="Maarouf M" first="Mohammad" last="Maarouf">Mohammad Maarouf</name><affiliation wicri:level="1"><mods:affiliation>Department of Stereotaxy and Functional Neurosurgery, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Stereotaxy and Functional Neurosurgery, University of Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Kuhn, Jens" sort="Kuhn, Jens" uniqKey="Kuhn J" first="Jens" last="Kuhn">Jens Kuhn</name><affiliation wicri:level="1"><mods:affiliation>Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Psychiatry and Psychotherapy, University of Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Zurowski, Mateusz" sort="Zurowski, Mateusz" uniqKey="Zurowski M" first="Mateusz" last="Zurowski">Mateusz Zurowski</name><affiliation wicri:level="1"><mods:affiliation>Department of Psychiatry, Department of Medicine, University of Toronto, University Health Network, Toronto, Ontario, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Psychiatry, Department of Medicine, University of Toronto, University Health Network, Toronto, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Moro, Elena" sort="Moro, Elena" uniqKey="Moro E" first="Elena" last="Moro">Elena Moro</name><affiliation wicri:level="1"><mods:affiliation>Movement Disorders Unit, Department of Psychiatry and Neurology, University Hospital Center (CHU) of Grenoble, Grenoble, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Movement Disorders Unit, Department of Psychiatry and Neurology, University Hospital Center (CHU) of Grenoble, Grenoble</wicri:regionArea></affiliation></author><author><name sortKey="Woopen, Christiane" sort="Woopen, Christiane" uniqKey="Woopen C" first="Christiane" last="Woopen">Christiane Woopen</name><affiliation wicri:level="1"><mods:affiliation>Research Unit Ethics, Institute for the History of Medicine and Medical Ethics, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit Ethics, Institute for the History of Medicine and Medical Ethics, University of Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Timmermann, Lars" sort="Timmermann, Lars" uniqKey="Timmermann L" first="Lars" last="Timmermann">Lars Timmermann</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, University of Cologne, Cologne</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:436610088435E9614BE05D633E7A803476F69355</idno><date when="2013" year="2013">2013</date><idno type="doi">10.1136/jnnp-2012-303670</idno><idno type="url">https://api.istex.fr/document/436610088435E9614BE05D633E7A803476F69355/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">001805</idno><idno type="wicri:Area/Main/Curation">001562</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">Patients’ expectations of deep brain stimulation, and subjective perceived outcome related to clinical measures in Parkinson's disease: a mixed-method approach</title><author><name sortKey="Maier, Franziska" sort="Maier, Franziska" uniqKey="Maier F" first="Franziska" last="Maier">Franziska Maier</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, University of Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Lewis, Catharine J" sort="Lewis, Catharine J" uniqKey="Lewis C" first="Catharine J" last="Lewis">Catharine J. Lewis</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, University of Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Horstkoetter, Nina" sort="Horstkoetter, Nina" uniqKey="Horstkoetter N" first="Nina" last="Horstkoetter">Nina Horstkoetter</name><affiliation wicri:level="1"><mods:affiliation>Research Unit Ethics, Institute for the History of Medicine and Medical Ethics, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit Ethics, Institute for the History of Medicine and Medical Ethics, University of Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Eggers, Carsten" sort="Eggers, Carsten" uniqKey="Eggers C" first="Carsten" last="Eggers">Carsten Eggers</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, University of Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Kalbe, Elke" sort="Kalbe, Elke" uniqKey="Kalbe E" first="Elke" last="Kalbe">Elke Kalbe</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, University of Cologne, Cologne</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Institute for Gerontology, University of Vechta, Vechta, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Gerontology, University of Vechta, Vechta</wicri:regionArea></affiliation></author><author><name sortKey="Maarouf, Mohammad" sort="Maarouf, Mohammad" uniqKey="Maarouf M" first="Mohammad" last="Maarouf">Mohammad Maarouf</name><affiliation wicri:level="1"><mods:affiliation>Department of Stereotaxy and Functional Neurosurgery, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Stereotaxy and Functional Neurosurgery, University of Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Kuhn, Jens" sort="Kuhn, Jens" uniqKey="Kuhn J" first="Jens" last="Kuhn">Jens Kuhn</name><affiliation wicri:level="1"><mods:affiliation>Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Psychiatry and Psychotherapy, University of Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Zurowski, Mateusz" sort="Zurowski, Mateusz" uniqKey="Zurowski M" first="Mateusz" last="Zurowski">Mateusz Zurowski</name><affiliation wicri:level="1"><mods:affiliation>Department of Psychiatry, Department of Medicine, University of Toronto, University Health Network, Toronto, Ontario, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Psychiatry, Department of Medicine, University of Toronto, University Health Network, Toronto, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Moro, Elena" sort="Moro, Elena" uniqKey="Moro E" first="Elena" last="Moro">Elena Moro</name><affiliation wicri:level="1"><mods:affiliation>Movement Disorders Unit, Department of Psychiatry and Neurology, University Hospital Center (CHU) of Grenoble, Grenoble, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Movement Disorders Unit, Department of Psychiatry and Neurology, University Hospital Center (CHU) of Grenoble, Grenoble</wicri:regionArea></affiliation></author><author><name sortKey="Woopen, Christiane" sort="Woopen, Christiane" uniqKey="Woopen C" first="Christiane" last="Woopen">Christiane Woopen</name><affiliation wicri:level="1"><mods:affiliation>Research Unit Ethics, Institute for the History of Medicine and Medical Ethics, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit Ethics, Institute for the History of Medicine and Medical Ethics, University of Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Timmermann, Lars" sort="Timmermann, Lars" uniqKey="Timmermann L" first="Lars" last="Timmermann">Lars Timmermann</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, University of Cologne, Cologne</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Neurology, Neurosurgery & Psychiatry</title><title level="j" type="abbrev">J Neurol Neurosurg Psychiatry</title><idno type="ISSN">0022-3050</idno><idno type="eISSN">1468-330X</idno><imprint><publisher>BMJ Publishing Group Ltd</publisher><date type="published" when="2013-11">2013-11</date><biblScope unit="volume">84</biblScope><biblScope unit="issue">11</biblScope><biblScope unit="page" from="1273">1273</biblScope></imprint><idno type="ISSN">0022-3050</idno></series><idno type="istex">436610088435E9614BE05D633E7A803476F69355</idno><idno type="DOI">10.1136/jnnp-2012-303670</idno><idno type="href">jnnp-84-1273.pdf</idno><idno type="ArticleID">jnnp-2012-303670</idno><idno type="PMID">23715910</idno><idno type="local">jnnp;84/11/1273</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0022-3050</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">Objective To study patients’ expectations of subthalamic deep brain stimulation (STN-DBS) and their subjective perceived outcome, by using qualitative and quantitative methods in Parkinson's disease (PD). Methods PD patients were prospectively examined before and 3 months after surgery. Semistructured interviews regarding preoperative expectations and postsurgical subjective perceived outcome were conducted. These were analysed using content analysis. For statistical analyses, patients were classified according to their subjective perceived outcome, resulting in three different subjective outcome groups (negative, mixed, positive outcome). The groups were used for multiple comparisons between and within each group regarding motor impairment, quality of life (QoL), neuropsychiatric status and cognitive functioning, using standard instruments. A logistic regression analysis was conducted to find predictors of subjective negative outcome. Receiver operating characteristic curves were used to analyse cut-off scores for predictive tests. Results Of the 30 PD patients participating, 8 had a subjective negative outcome, 8 a mixed and 14 a positive outcome. All groups significantly improved in motor functioning. Patients with subjective negative outcome were characterised by preoperative unrealistic expectations, no postsurgical improvement in QoL, and significantly higher presurgical and postsurgical apathy and depression scores. Higher preoperative apathy and depression scores were significant predictors of negative subjective outcome. Cut-off scores for apathy and depression were identified. Conclusions The mixed-method approach proved useful in examining a patient's subjective perception of STN-DBS outcome. Our results show that significant motor improvement does not necessarily lead to a positive subjective outcome. Moreover, PD patients should be screened carefully before surgery regarding apathy and depression. (DRKS-ID: DRKS00003221).</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001562 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 001562 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonV1
|flux= Main
|étape= Curation
|type= RBID
|clé= ISTEX:436610088435E9614BE05D633E7A803476F69355
|texte= Patients’ expectations of deep brain stimulation, and subjective perceived outcome related to clinical measures in Parkinson's disease: a mixed-method approach
}}
| This area was generated with Dilib version V0.6.23. |  |