Mortality from Parkinson's disease: A population‐based prospective study (NEDICES)
Identifieur interne : 000239 ( Main/Curation ); précédent : 000238; suivant : 000240Mortality from Parkinson's disease: A population‐based prospective study (NEDICES)
Auteurs : Ignacio J. Posada [Espagne] ; Julián Benito-Le N [Espagne] ; Elan D. Louis [États-Unis] ; Rocío Trincado [Espagne] ; Alberto Villarejo [Espagne] ; María José Medrano [Espagne] ; Félix Bermejo-Pareja [Espagne]Source :
- Movement Disorders [ 0885-3185 ] ; 2011-12.
English descriptors
- KwdEn :
Abstract
Most studies of mortality in Parkinson's disease have been clinical studies, yielding results that are not representative of the general population. We assessed the risk of mortality from Parkinson's disease in the Neurological Disorders in Central Spain (NEDICES) study, a prospective population‐based study in which Parkinson's disease patients who were not ascertained through medical practitioners were also included. The cohort consisted of 5262 elderly subjects (mean baseline age, 73.0 years), including 81 with Parkinson's disease at baseline (1994–1995). Thirteen‐year mortality was assessed. Two thousand seven hundred and one of 5262 subjects (51.3%) died over a median follow‐up of 12.0 years (range, 0.04–14.8 years), including 66 of 81 subjects (81.5%) with Parkinson's disease at baseline and 2635 of 5181 subjects (50.8%) without Parkinson's disease at baseline. In an unadjusted Cox model, the hazard ratio of mortality was increased in subjects with Parkinson's disease (hazard ratio, 2.29; 95% confidence interval, 1.80–2.93; P < .001) versus subjects without Parkinson's disease (reference group). In a Cox model that adjusted for a variety of demographic factors and comorbidities, the risk of mortality remained elevated in subjects with Parkinson's disease (hazard ratio, 1.75; 95% CI, 1.32–2.31, P < .001). In additional Cox models, Parkinson's disease patients with dementia had particularly high risks of mortality (adjusted hazard ratio, 2.62; 95% CI, 1.40–4.90; P < .001). In this prospective population‐based study, Parkinson's disease was an independent predictor of mortality in the elderly. Parkinson's disease patients with dementia had particularly high risks of mortality. © 2011 Movement Disorder Society
Url:
DOI: 10.1002/mds.23921
Links toward previous steps (curation, corpus...)
- to stream Main, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000286
Links to Exploration step
ISTEX:BB974B5A59EFFA3263E9F391A4F0785C6B58D23FLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Mortality from Parkinson's disease: A population‐based prospective study (NEDICES)</title><author><name sortKey="Posada, Ignacio J" sort="Posada, Ignacio J" uniqKey="Posada I" first="Ignacio J." last="Posada">Ignacio J. Posada</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University Hospital “12 de Octubre,” Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Neurology, University Hospital “12 de Octubre,” Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Faculty of Medicine, Complutense University, Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Faculty of Medicine, Complutense University, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Benito E N, Julian" sort="Benito E N, Julian" uniqKey="Benito E N J" first="Julián" last="Benito-Le N">Julián Benito-Le N</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University Hospital “12 de Octubre,” Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Neurology, University Hospital “12 de Octubre,” Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Faculty of Medicine, Complutense University, Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Faculty of Medicine, Complutense University, Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Louis, Elan D" sort="Louis, Elan D" uniqKey="Louis E" first="Elan D." last="Louis">Elan D. Louis</name><affiliation wicri:level="1"><mods:affiliation>G.H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>G.H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York</wicri:regionArea></affiliation></author><author><name sortKey="Trincado, Rocio" sort="Trincado, Rocio" uniqKey="Trincado R" first="Rocío" last="Trincado">Rocío Trincado</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University Hospital “12 de Octubre,” Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Neurology, University Hospital “12 de Octubre,” Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Villarejo, Alberto" sort="Villarejo, Alberto" uniqKey="Villarejo A" first="Alberto" last="Villarejo">Alberto Villarejo</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University Hospital “12 de Octubre,” Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Neurology, University Hospital “12 de Octubre,” Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Faculty of Medicine, Complutense University, Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Faculty of Medicine, Complutense University, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Medrano, Maria Jose" sort="Medrano, Maria Jose" uniqKey="Medrano M" first="María José" last="Medrano">María José Medrano</name><affiliation wicri:level="1"><mods:affiliation>Unit of Vascular Risk Factors, National Center for Epidemiology, ISCIII, Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Unit of Vascular Risk Factors, National Center for Epidemiology, ISCIII, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Bermejo Areja, Felix" sort="Bermejo Areja, Felix" uniqKey="Bermejo Areja F" first="Félix" last="Bermejo-Pareja">Félix Bermejo-Pareja</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University Hospital “12 de Octubre,” Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Neurology, University Hospital “12 de Octubre,” Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Faculty of Medicine, Complutense University, Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Faculty of Medicine, Complutense University, Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:BB974B5A59EFFA3263E9F391A4F0785C6B58D23F</idno><date when="2011" year="2011">2011</date><idno type="doi">10.1002/mds.23921</idno><idno type="url">https://api.istex.fr/document/BB974B5A59EFFA3263E9F391A4F0785C6B58D23F/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">000286</idno><idno type="wicri:Area/Main/Curation">000239</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Mortality from Parkinson's disease: A population‐based prospective study (NEDICES)</title><author><name sortKey="Posada, Ignacio J" sort="Posada, Ignacio J" uniqKey="Posada I" first="Ignacio J." last="Posada">Ignacio J. Posada</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University Hospital “12 de Octubre,” Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Neurology, University Hospital “12 de Octubre,” Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Faculty of Medicine, Complutense University, Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Faculty of Medicine, Complutense University, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Benito E N, Julian" sort="Benito E N, Julian" uniqKey="Benito E N J" first="Julián" last="Benito-Le N">Julián Benito-Le N</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University Hospital “12 de Octubre,” Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Neurology, University Hospital “12 de Octubre,” Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Faculty of Medicine, Complutense University, Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Faculty of Medicine, Complutense University, Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Louis, Elan D" sort="Louis, Elan D" uniqKey="Louis E" first="Elan D." last="Louis">Elan D. Louis</name><affiliation wicri:level="1"><mods:affiliation>G.H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>G.H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York</wicri:regionArea></affiliation></author><author><name sortKey="Trincado, Rocio" sort="Trincado, Rocio" uniqKey="Trincado R" first="Rocío" last="Trincado">Rocío Trincado</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University Hospital “12 de Octubre,” Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Neurology, University Hospital “12 de Octubre,” Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Villarejo, Alberto" sort="Villarejo, Alberto" uniqKey="Villarejo A" first="Alberto" last="Villarejo">Alberto Villarejo</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University Hospital “12 de Octubre,” Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Neurology, University Hospital “12 de Octubre,” Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Faculty of Medicine, Complutense University, Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Faculty of Medicine, Complutense University, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Medrano, Maria Jose" sort="Medrano, Maria Jose" uniqKey="Medrano M" first="María José" last="Medrano">María José Medrano</name><affiliation wicri:level="1"><mods:affiliation>Unit of Vascular Risk Factors, National Center for Epidemiology, ISCIII, Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Unit of Vascular Risk Factors, National Center for Epidemiology, ISCIII, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Bermejo Areja, Felix" sort="Bermejo Areja, Felix" uniqKey="Bermejo Areja F" first="Félix" last="Bermejo-Pareja">Félix Bermejo-Pareja</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University Hospital “12 de Octubre,” Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Neurology, University Hospital “12 de Octubre,” Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Faculty of Medicine, Complutense University, Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Faculty of Medicine, Complutense University, Madrid</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2011-12">2011-12</date><biblScope unit="volume">26</biblScope><biblScope unit="issue">14</biblScope><biblScope unit="page" from="2522">2522</biblScope><biblScope unit="page" to="2529">2529</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">BB974B5A59EFFA3263E9F391A4F0785C6B58D23F</idno><idno type="DOI">10.1002/mds.23921</idno><idno type="ArticleID">MDS23921</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson's disease</term><term>elderly</term><term>epidemiology</term><term>mortality</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Most studies of mortality in Parkinson's disease have been clinical studies, yielding results that are not representative of the general population. We assessed the risk of mortality from Parkinson's disease in the Neurological Disorders in Central Spain (NEDICES) study, a prospective population‐based study in which Parkinson's disease patients who were not ascertained through medical practitioners were also included. The cohort consisted of 5262 elderly subjects (mean baseline age, 73.0 years), including 81 with Parkinson's disease at baseline (1994–1995). Thirteen‐year mortality was assessed. Two thousand seven hundred and one of 5262 subjects (51.3%) died over a median follow‐up of 12.0 years (range, 0.04–14.8 years), including 66 of 81 subjects (81.5%) with Parkinson's disease at baseline and 2635 of 5181 subjects (50.8%) without Parkinson's disease at baseline. In an unadjusted Cox model, the hazard ratio of mortality was increased in subjects with Parkinson's disease (hazard ratio, 2.29; 95% confidence interval, 1.80–2.93; P < .001) versus subjects without Parkinson's disease (reference group). In a Cox model that adjusted for a variety of demographic factors and comorbidities, the risk of mortality remained elevated in subjects with Parkinson's disease (hazard ratio, 1.75; 95% CI, 1.32–2.31, P < .001). In additional Cox models, Parkinson's disease patients with dementia had particularly high risks of mortality (adjusted hazard ratio, 2.62; 95% CI, 1.40–4.90; P < .001). In this prospective population‐based study, Parkinson's disease was an independent predictor of mortality in the elderly. Parkinson's disease patients with dementia had particularly high risks of mortality. © 2011 Movement Disorder Society</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000239 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 000239 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonV1
|flux= Main
|étape= Curation
|type= RBID
|clé= ISTEX:BB974B5A59EFFA3263E9F391A4F0785C6B58D23F
|texte= Mortality from Parkinson's disease: A population‐based prospective study (NEDICES)
}}
| This area was generated with Dilib version V0.6.23. |  |