Profile of cognitive impairment in dementia associated with Parkinson’s disease compared with Alzheimer’s disease
Identifieur interne : 002B45 ( Main/Corpus ); précédent : 002B44; suivant : 002B46Profile of cognitive impairment in dementia associated with Parkinson’s disease compared with Alzheimer’s disease
Auteurs : Kolbjorn Bronnick ; Murat Emre ; Roger Lane ; Sibel Tekin ; Dag AarslandSource :
- Journal of Neurology, Neurosurgery & Psychiatry [ 0022-3050 ] ; 2007-10.
Abstract
Objective: To compare the profile of cognitive impairment in Alzheimer’s disease (AD) with dementia associated with Parkinson’s disease (PDD). Methods: Neuropsychological assessment was performed in 488 patients with PDD and 488 patients with AD using the Mini-Mental State Examination (MMSE) and the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog). Logistic regression analysis was used to investigate whether the diagnosis could be accurately predicted from the cognitive profile. Additionally, the cognitive profiles were compared with a normative group using standardised effect sizes (Cohen’s d). Results: Diagnosis was predicted from the cognitive profile, with an overall accuracy of 74.7%. Poor performance of the AD patients on the orientation test in ADAS-cog best discriminated between the groups, followed by poor performance of the PDD patients on the attentional task in MMSE. Both groups showed memory impairment, AD patients performing worse than PDD patients. Conclusion: The cognitive profile in PDD differs significantly from that in AD. Performance on tests of orientation and attention are best in differentiating the groups.
Url:
DOI: 10.1136/jnnp.2006.108076
Links to Exploration step
ISTEX:3945D7E135EA9C1F422E54FCD30B65D1E17A6BD6Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Profile of cognitive impairment in dementia associated with Parkinson’s disease compared with Alzheimer’s disease</title><author><name sortKey="Bronnick, Kolbjorn" sort="Bronnick, Kolbjorn" uniqKey="Bronnick K" first="Kolbjorn" last="Bronnick">Kolbjorn Bronnick</name><affiliation><mods:affiliation>Norwegian Centre for Movement Disorders, Stavanger University Hospital, Helse Stavanger, Norway</mods:affiliation></affiliation></author><author><name sortKey="Emre, Murat" sort="Emre, Murat" uniqKey="Emre M" first="Murat" last="Emre">Murat Emre</name><affiliation><mods:affiliation>Department of Neurology, Faculty of Medicine, Istanbul University, Turkey</mods:affiliation></affiliation></author><author><name sortKey="Lane, Roger" sort="Lane, Roger" uniqKey="Lane R" first="Roger" last="Lane">Roger Lane</name><affiliation><mods:affiliation>Novartis Pharmaceuticals, East Hanover, New Jersey, USA</mods:affiliation></affiliation></author><author><name sortKey="Tekin, Sibel" sort="Tekin, Sibel" uniqKey="Tekin S" first="Sibel" last="Tekin">Sibel Tekin</name><affiliation><mods:affiliation>Novartis Pharmaceuticals, East Hanover, New Jersey, USA</mods:affiliation></affiliation></author><author><name sortKey="Aarsland, Dag" sort="Aarsland, Dag" uniqKey="Aarsland D" first="Dag" last="Aarsland">Dag Aarsland</name><affiliation><mods:affiliation>Norwegian Centre for Movement Disorders, Stavanger University Hospital, Helse Stavanger, Norway</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:3945D7E135EA9C1F422E54FCD30B65D1E17A6BD6</idno><date when="2007" year="2007">2007</date><idno type="doi">10.1136/jnnp.2006.108076</idno><idno type="url">https://api.istex.fr/document/3945D7E135EA9C1F422E54FCD30B65D1E17A6BD6/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">002B45</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Profile of cognitive impairment in dementia associated with Parkinson’s disease compared with Alzheimer’s disease</title><author><name sortKey="Bronnick, Kolbjorn" sort="Bronnick, Kolbjorn" uniqKey="Bronnick K" first="Kolbjorn" last="Bronnick">Kolbjorn Bronnick</name><affiliation><mods:affiliation>Norwegian Centre for Movement Disorders, Stavanger University Hospital, Helse Stavanger, Norway</mods:affiliation></affiliation></author><author><name sortKey="Emre, Murat" sort="Emre, Murat" uniqKey="Emre M" first="Murat" last="Emre">Murat Emre</name><affiliation><mods:affiliation>Department of Neurology, Faculty of Medicine, Istanbul University, Turkey</mods:affiliation></affiliation></author><author><name sortKey="Lane, Roger" sort="Lane, Roger" uniqKey="Lane R" first="Roger" last="Lane">Roger Lane</name><affiliation><mods:affiliation>Novartis Pharmaceuticals, East Hanover, New Jersey, USA</mods:affiliation></affiliation></author><author><name sortKey="Tekin, Sibel" sort="Tekin, Sibel" uniqKey="Tekin S" first="Sibel" last="Tekin">Sibel Tekin</name><affiliation><mods:affiliation>Novartis Pharmaceuticals, East Hanover, New Jersey, USA</mods:affiliation></affiliation></author><author><name sortKey="Aarsland, Dag" sort="Aarsland, Dag" uniqKey="Aarsland D" first="Dag" last="Aarsland">Dag Aarsland</name><affiliation><mods:affiliation>Norwegian Centre for Movement Disorders, Stavanger University Hospital, Helse Stavanger, Norway</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Neurology, Neurosurgery & Psychiatry</title><title level="j" type="abbrev">J Neurol Neurosurg Psychiatry</title><idno type="ISSN">0022-3050</idno><idno type="eISSN">1468-330X</idno><imprint><publisher>BMJ Publishing Group Ltd</publisher><date type="published" when="2007-10">2007-10</date><biblScope unit="volume">78</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="1064">1064</biblScope></imprint><idno type="ISSN">0022-3050</idno></series><idno type="istex">3945D7E135EA9C1F422E54FCD30B65D1E17A6BD6</idno><idno type="DOI">10.1136/jnnp.2006.108076</idno><idno type="href">jnnp-78-1064.pdf</idno><idno type="ArticleID">jn108076</idno><idno type="PMID">17287236</idno><idno type="local">jnnp;78/10/1064</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0022-3050</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">Objective: To compare the profile of cognitive impairment in Alzheimer’s disease (AD) with dementia associated with Parkinson’s disease (PDD). Methods: Neuropsychological assessment was performed in 488 patients with PDD and 488 patients with AD using the Mini-Mental State Examination (MMSE) and the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog). Logistic regression analysis was used to investigate whether the diagnosis could be accurately predicted from the cognitive profile. Additionally, the cognitive profiles were compared with a normative group using standardised effect sizes (Cohen’s d). Results: Diagnosis was predicted from the cognitive profile, with an overall accuracy of 74.7%. Poor performance of the AD patients on the orientation test in ADAS-cog best discriminated between the groups, followed by poor performance of the PDD patients on the attentional task in MMSE. Both groups showed memory impairment, AD patients performing worse than PDD patients. Conclusion: The cognitive profile in PDD differs significantly from that in AD. Performance on tests of orientation and attention are best in differentiating the groups.</div></front></TEI><istex><corpusName>bmj</corpusName><author><json:item><name>Kolbjorn Bronnick</name><affiliations><json:string>Norwegian Centre for Movement Disorders, Stavanger University Hospital, Helse Stavanger, Norway</json:string></affiliations></json:item><json:item><name>Murat Emre</name><affiliations><json:string>Department of Neurology, Faculty of Medicine, Istanbul University, Turkey</json:string></affiliations></json:item><json:item><name>Roger Lane</name><affiliations><json:string>Novartis Pharmaceuticals, East Hanover, New Jersey, USA</json:string></affiliations></json:item><json:item><name>Sibel Tekin</name><affiliations><json:string>Novartis Pharmaceuticals, East Hanover, New Jersey, USA</json:string></affiliations></json:item><json:item><name>Dag Aarsland</name><affiliations><json:string>Norwegian Centre for Movement Disorders, Stavanger University Hospital, Helse Stavanger, Norway</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Papers</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Memory disorders (neurology)</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Drugs: CNS (not psychiatric)</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Memory disorders (psychiatry)</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Psychiatry of old age</value></json:item></subject><language><json:string>eng</json:string></language><abstract>Objective: To compare the profile of cognitive impairment in Alzheimer’s disease (AD) with dementia associated with Parkinson’s disease (PDD). Methods: Neuropsychological assessment was performed in 488 patients with PDD and 488 patients with AD using the Mini-Mental State Examination (MMSE) and the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog). Logistic regression analysis was used to investigate whether the diagnosis could be accurately predicted from the cognitive profile. Additionally, the cognitive profiles were compared with a normative group using standardised effect sizes (Cohen’s d). Results: Diagnosis was predicted from the cognitive profile, with an overall accuracy of 74.7%. Poor performance of the AD patients on the orientation test in ADAS-cog best discriminated between the groups, followed by poor performance of the PDD patients on the attentional task in MMSE. Both groups showed memory impairment, AD patients performing worse than PDD patients. Conclusion: The cognitive profile in PDD differs significantly from that in AD. Performance on tests of orientation and attention are best in differentiating the groups.</abstract><qualityIndicators><score>5.755</score><pdfVersion>1.2</pdfVersion><pdfPageSize>595.276 x 793.701 pts</pdfPageSize><refBibsNative>false</refBibsNative><keywordCount>5</keywordCount><abstractCharCount>1165</abstractCharCount><pdfWordCount>3787</pdfWordCount><pdfCharCount>25909</pdfCharCount><pdfPageCount>5</pdfPageCount><abstractWordCount>164</abstractWordCount></qualityIndicators><title>Profile of cognitive impairment in dementia associated with Parkinson’s disease compared with Alzheimer’s disease</title><pmid><json:string>17287236</json:string></pmid><genre><json:string>research-article</json:string></genre><host><volume>78</volume><pages><first>1064</first></pages><issn><json:string>0022-3050</json:string></issn><issue>10</issue><genre></genre><language><json:string>unknown</json:string></language><eissn><json:string>1468-330X</json:string></eissn><title>Journal of Neurology, Neurosurgery & Psychiatry</title></host><publicationDate>2007</publicationDate><copyrightDate>2007</copyrightDate><doi><json:string>10.1136/jnnp.2006.108076</json:string></doi><id>3945D7E135EA9C1F422E54FCD30B65D1E17A6BD6</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/3945D7E135EA9C1F422E54FCD30B65D1E17A6BD6/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/3945D7E135EA9C1F422E54FCD30B65D1E17A6BD6/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/3945D7E135EA9C1F422E54FCD30B65D1E17A6BD6/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Profile of cognitive impairment in dementia associated with Parkinson’s disease compared with Alzheimer’s disease</title><respStmt xml:id="ISTEX-API" resp="Références bibliographiques récupérées via GROBID" name="ISTEX-API (INIST-CNRS)"></respStmt></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>BMJ Publishing Group Ltd</publisher><availability><p>BMJ</p></availability><date>2007-02-07</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Profile of cognitive impairment in dementia associated with Parkinson’s disease compared with Alzheimer’s disease</title><author><persName><forename type="first">Kolbjorn</forename><surname>Bronnick</surname></persName><affiliation>Norwegian Centre for Movement Disorders, Stavanger University Hospital, Helse Stavanger, Norway</affiliation></author><author><persName><forename type="first">Murat</forename><surname>Emre</surname></persName><affiliation>Department of Neurology, Faculty of Medicine, Istanbul University, Turkey</affiliation></author><author><persName><forename type="first">Roger</forename><surname>Lane</surname></persName><affiliation>Novartis Pharmaceuticals, East Hanover, New Jersey, USA</affiliation></author><author><persName><forename type="first">Sibel</forename><surname>Tekin</surname></persName><affiliation>Novartis Pharmaceuticals, East Hanover, New Jersey, USA</affiliation></author><author><persName><forename type="first">Dag</forename><surname>Aarsland</surname></persName><affiliation>Norwegian Centre for Movement Disorders, Stavanger University Hospital, Helse Stavanger, Norway</affiliation></author></analytic><monogr><title level="j">Journal of Neurology, Neurosurgery & Psychiatry</title><title level="j" type="abbrev">J Neurol Neurosurg Psychiatry</title><idno type="pISSN">0022-3050</idno><idno type="eISSN">1468-330X</idno><imprint><publisher>BMJ Publishing Group Ltd</publisher><date type="published" when="2007-10"></date><biblScope unit="volume">78</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="1064">1064</biblScope></imprint></monogr><idno type="istex">3945D7E135EA9C1F422E54FCD30B65D1E17A6BD6</idno><idno type="DOI">10.1136/jnnp.2006.108076</idno><idno type="href">jnnp-78-1064.pdf</idno><idno type="ArticleID">jn108076</idno><idno type="PMID">17287236</idno><idno type="local">jnnp;78/10/1064</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2007-02-07</date></creation><langUsage><language ident="en">en</language></langUsage><abstract><p>Objective: To compare the profile of cognitive impairment in Alzheimer’s disease (AD) with dementia associated with Parkinson’s disease (PDD). Methods: Neuropsychological assessment was performed in 488 patients with PDD and 488 patients with AD using the Mini-Mental State Examination (MMSE) and the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog). Logistic regression analysis was used to investigate whether the diagnosis could be accurately predicted from the cognitive profile. Additionally, the cognitive profiles were compared with a normative group using standardised effect sizes (Cohen’s d). Results: Diagnosis was predicted from the cognitive profile, with an overall accuracy of 74.7%. Poor performance of the AD patients on the orientation test in ADAS-cog best discriminated between the groups, followed by poor performance of the PDD patients on the attentional task in MMSE. Both groups showed memory impairment, AD patients performing worse than PDD patients. Conclusion: The cognitive profile in PDD differs significantly from that in AD. Performance on tests of orientation and attention are best in differentiating the groups.</p></abstract><textClass><keywords scheme="keyword"><list><head>hwp-journal-coll</head><item><term>Memory disorders (neurology)</term></item></list></keywords></textClass><textClass><keywords scheme="keyword"><list><head>hwp-journal-coll</head><item><term>Drugs: CNS (not psychiatric)</term></item></list></keywords></textClass><textClass><keywords scheme="keyword"><list><head>hwp-journal-coll</head><item><term>Memory disorders (psychiatry)</term></item></list></keywords></textClass><textClass><keywords scheme="keyword"><list><head>hwp-journal-coll</head><item><term>Psychiatry of old age</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2007-02-07">Created</change><change when="2007-10">Published</change><change xml:id="refBibs-istex" who="#ISTEX-API" when="2016-3-14">References added</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/3945D7E135EA9C1F422E54FCD30B65D1E17A6BD6/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="corpus bmj" wicri:toSee="no header"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="no"</istex:xmlDeclaration><istex:docType PUBLIC="-//NLM//DTD Journal Archiving and Interchange DTD v2.3 20070202//EN" URI="archivearticle.dtd" name="istex:docType"></istex:docType><istex:document><article article-type="research-article" xml:lang="EN"><front><journal-meta><journal-id journal-id-type="hwp">jnnp</journal-id><journal-id journal-id-type="nlm-ta">J Neurol Neurosurg Psychiatry</journal-id><journal-id journal-id-type="publisher-id">jnnp</journal-id><journal-title>Journal of Neurology, Neurosurgery & Psychiatry</journal-title><abbrev-journal-title abbrev-type="publisher">J Neurol Neurosurg Psychiatry</abbrev-journal-title><issn pub-type="ppub">0022-3050</issn><issn pub-type="epub">1468-330X</issn><publisher><publisher-name>BMJ Publishing Group Ltd</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">jn108076</article-id><article-id pub-id-type="doi">10.1136/jnnp.2006.108076</article-id><article-id pub-id-type="other">jnnp;78/10/1064</article-id><article-id pub-id-type="other">jnnp;jnnp.2006.108076</article-id><article-id pub-id-type="pmid">17287236</article-id><article-id pub-id-type="other">1064</article-id><article-id pub-id-type="other">jnnp.2006.108076</article-id><article-categories><subj-group subj-group-type="heading"><subject content-type="original">Papers</subject></subj-group><subj-group subj-group-type="hwp-journal-coll"><subject>Memory disorders (neurology)</subject></subj-group><subj-group subj-group-type="hwp-journal-coll"><subject>Drugs: CNS (not psychiatric)</subject></subj-group><subj-group subj-group-type="hwp-journal-coll"><subject>Memory disorders (psychiatry)</subject></subj-group><subj-group subj-group-type="hwp-journal-coll"><subject>Psychiatry of old age</subject></subj-group></article-categories><title-group><article-title>Profile of cognitive impairment in dementia associated with Parkinson’s disease compared with Alzheimer’s disease</article-title><alt-title alt-title-type="running-head">Cognitive profiles in AD and PDD</alt-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Bronnick</surname><given-names>Kolbjorn</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Emre</surname><given-names>Murat</given-names></name><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Lane</surname><given-names>Roger</given-names></name><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Tekin</surname><given-names>Sibel</given-names></name><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Aarsland</surname><given-names>Dag</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib></contrib-group><aff id="aff1"><label>1</label> <addr-line>Norwegian Centre for Movement Disorders, Stavanger University Hospital, Helse Stavanger, Norway</addr-line> </aff><aff id="aff2"><label>2</label> <addr-line>Department of Neurology, Faculty of Medicine, Istanbul University, Turkey</addr-line> </aff><aff id="aff3"><label>3</label> <addr-line>Novartis Pharmaceuticals, East Hanover, New Jersey, USA</addr-line> </aff><author-notes><corresp>Kolbjørn Brønnick, Psychiatric Clinic, Helse Stavanger, PO box 8100, 4068 Stavanger, Norway; <email xlink:type="simple">bronnick@gmail.com</email></corresp></author-notes><pub-date pub-type="ppub"><month>10</month><year>2007</year></pub-date><pub-date pub-type="epub-original"><day>6</day><month>2</month><year>2007</year></pub-date><pub-date pub-type="epub"><day>7</day><month>2</month><year>2007</year></pub-date><volume>78</volume><volume-id pub-id-type="other">78</volume-id><volume-id pub-id-type="other">78</volume-id><issue>10</issue><issue-id pub-id-type="other">jnnp;78/10</issue-id><issue-id pub-id-type="other">10</issue-id><issue-id pub-id-type="other">78/10</issue-id><fpage>1064</fpage><history><date date-type="received"><day>2</day><month>10</month><year>2006</year></date><date date-type="rev-recd"><day>23</day><month>1</month><year>2007</year></date><date date-type="accepted"><day>27</day><month>1</month><year>2007</year></date></history><permissions><copyright-statement>2007 BMJ Publishing Group</copyright-statement><copyright-year>2007</copyright-year></permissions><self-uri content-type="pdf" xlink:role="full-text" xlink:href="jnnp-78-1064.pdf"></self-uri><abstract><sec><title>Objective:</title><p>To compare the profile of cognitive impairment in Alzheimer’s disease (AD) with dementia associated with Parkinson’s disease (PDD).</p></sec><sec><title>Methods:</title><p>Neuropsychological assessment was performed in 488 patients with PDD and 488 patients with AD using the Mini-Mental State Examination (MMSE) and the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog). Logistic regression analysis was used to investigate whether the diagnosis could be accurately predicted from the cognitive profile. Additionally, the cognitive profiles were compared with a normative group using standardised effect sizes (Cohen’s d).</p></sec><sec><title>Results:</title><p>Diagnosis was predicted from the cognitive profile, with an overall accuracy of 74.7%. Poor performance of the AD patients on the orientation test in ADAS-cog best discriminated between the groups, followed by poor performance of the PDD patients on the attentional task in MMSE. Both groups showed memory impairment, AD patients performing worse than PDD patients.</p></sec><sec><title>Conclusion:</title><p>The cognitive profile in PDD differs significantly from that in AD. Performance on tests of orientation and attention are best in differentiating the groups.</p></sec></abstract></article-meta></front></article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Profile of cognitive impairment in dementia associated with Parkinson’s disease compared with Alzheimer’s disease</title></titleInfo><titleInfo type="alternative" lang="en" contentType="CDATA"><title>Profile of cognitive impairment in dementia associated with Parkinson’s disease compared with Alzheimer’s disease</title></titleInfo><name type="personal"><namePart type="given">Kolbjorn</namePart><namePart type="family">Bronnick</namePart><affiliation>Norwegian Centre for Movement Disorders, Stavanger University Hospital, Helse Stavanger, Norway</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Murat</namePart><namePart type="family">Emre</namePart><affiliation>Department of Neurology, Faculty of Medicine, Istanbul University, Turkey</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Roger</namePart><namePart type="family">Lane</namePart><affiliation>Novartis Pharmaceuticals, East Hanover, New Jersey, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Sibel</namePart><namePart type="family">Tekin</namePart><affiliation>Novartis Pharmaceuticals, East Hanover, New Jersey, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Dag</namePart><namePart type="family">Aarsland</namePart><affiliation>Norwegian Centre for Movement Disorders, Stavanger University Hospital, Helse Stavanger, Norway</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="research-article"></genre><subject><genre>hwp-journal-coll</genre><topic>Memory disorders (neurology)</topic></subject><subject><genre>hwp-journal-coll</genre><topic>Drugs: CNS (not psychiatric)</topic></subject><subject><genre>hwp-journal-coll</genre><topic>Memory disorders (psychiatry)</topic></subject><subject><genre>hwp-journal-coll</genre><topic>Psychiatry of old age</topic></subject><originInfo><publisher>BMJ Publishing Group Ltd</publisher><dateIssued encoding="w3cdtf">2007-10</dateIssued><dateCreated encoding="w3cdtf">2007-02-07</dateCreated><copyrightDate encoding="w3cdtf">2007</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract>Objective: To compare the profile of cognitive impairment in Alzheimer’s disease (AD) with dementia associated with Parkinson’s disease (PDD). Methods: Neuropsychological assessment was performed in 488 patients with PDD and 488 patients with AD using the Mini-Mental State Examination (MMSE) and the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog). Logistic regression analysis was used to investigate whether the diagnosis could be accurately predicted from the cognitive profile. Additionally, the cognitive profiles were compared with a normative group using standardised effect sizes (Cohen’s d). Results: Diagnosis was predicted from the cognitive profile, with an overall accuracy of 74.7%. Poor performance of the AD patients on the orientation test in ADAS-cog best discriminated between the groups, followed by poor performance of the PDD patients on the attentional task in MMSE. Both groups showed memory impairment, AD patients performing worse than PDD patients. Conclusion: The cognitive profile in PDD differs significantly from that in AD. Performance on tests of orientation and attention are best in differentiating the groups.</abstract><relatedItem type="host"><titleInfo><title>Journal of Neurology, Neurosurgery & Psychiatry</title></titleInfo><titleInfo type="abbreviated"><title>J Neurol Neurosurg Psychiatry</title></titleInfo><genre type="Journal">journal</genre><identifier type="ISSN">0022-3050</identifier><identifier type="eISSN">1468-330X</identifier><identifier type="PublisherID">jnnp</identifier><identifier type="PublisherID-hwp">jnnp</identifier><identifier type="PublisherID-nlm-ta">J Neurol Neurosurg Psychiatry</identifier><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>78</number></detail><detail type="issue"><caption>no.</caption><number>10</number></detail><extent unit="pages"><start>1064</start></extent></part></relatedItem><identifier type="istex">3945D7E135EA9C1F422E54FCD30B65D1E17A6BD6</identifier><identifier type="DOI">10.1136/jnnp.2006.108076</identifier><identifier type="href">jnnp-78-1064.pdf</identifier><identifier type="ArticleID">jn108076</identifier><identifier type="PMID">17287236</identifier><identifier type="local">jnnp;78/10/1064</identifier><accessCondition type="use and reproduction" contentType="copyright">2007 BMJ Publishing Group</accessCondition><recordInfo><recordContentSource>BMJ</recordContentSource></recordInfo></mods></metadata><annexes><json:item><original>true</original><mimetype>image/jpeg</mimetype><extension>jpeg</extension><uri>https://api.istex.fr/document/3945D7E135EA9C1F422E54FCD30B65D1E17A6BD6/annexes/jpeg</uri></json:item></annexes><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002B45 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Corpus/biblio.hfd -nk 002B45 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonV1
|flux= Main
|étape= Corpus
|type= RBID
|clé= ISTEX:3945D7E135EA9C1F422E54FCD30B65D1E17A6BD6
|texte= Profile of cognitive impairment in dementia associated with Parkinson’s disease compared with Alzheimer’s disease
}}
| This area was generated with Dilib version V0.6.23. |  |