Recommendations for the diagnosis and management of Alzheimer's disease and other disorders associated with dementia: EFNS guideline
Identifieur interne : 002569 ( Main/Corpus ); précédent : 002568; suivant : 002570Recommendations for the diagnosis and management of Alzheimer's disease and other disorders associated with dementia: EFNS guideline
Auteurs : G. Waldemar ; B. Dubois ; M. Emre ; J. Georges ; I. G. Mckeith ; M. Rossor ; P. Scheltens ; P. Tariska ; B. WinbladSource :
- European Journal of Neurology [ 1351-5101 ] ; 2007-01.
English descriptors
- KwdEn :
Abstract
The aim of this international guideline on dementia was to present a peer‐reviewed evidence‐based statement for the guidance of practice for clinical neurologists, geriatricians, psychiatrists, and other specialist physicians responsible for the care of patients with dementia. It covers major aspects of diagnostic evaluation and treatment, with particular emphasis on the type of patient often referred to the specialist physician. The main focus is Alzheimer's disease, but many of the recommendations apply to dementia disorders in general. The task force working group considered and classified evidence from original research reports, meta‐analysis, and systematic reviews, published before January 2006. The evidence was classified and consensus recommendations graded according to the EFNS guidance. Where there was a lack of evidence, but clear consensus, good practice points were provided. The recommendations for clinical diagnosis, blood tests, neuroimaging, electroencephalography (EEG), cerebrospinal fluid (CSF) analysis, genetic testing, tissue biopsy, disclosure of diagnosis, treatment of Alzheimer's disease, and counselling and support for caregivers were all revised when compared with the previous EFNS guideline. New recommendations were added for the treatment of vascular dementia, Parkinson's disease dementia, and dementia with Lewy bodies, for monitoring treatment, for treatment of behavioural and psychological symptoms in dementia, and for legal issues. The specialist physician plays an important role together with primary care physicians in the multidisciplinary dementia teams, which have been established throughout Europe. This guideline may contribute to the definition of the role of the specialist physician in providing dementia health care.
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DOI: 10.1111/j.1468-1331.2006.01605.x
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It covers major aspects of diagnostic evaluation and treatment, with particular emphasis on the type of patient often referred to the specialist physician. The main focus is Alzheimer's disease, but many of the recommendations apply to dementia disorders in general. The task force working group considered and classified evidence from original research reports, meta‐analysis, and systematic reviews, published before January 2006. The evidence was classified and consensus recommendations graded according to the EFNS guidance. Where there was a lack of evidence, but clear consensus, good practice points were provided. The recommendations for clinical diagnosis, blood tests, neuroimaging, electroencephalography (EEG), cerebrospinal fluid (CSF) analysis, genetic testing, tissue biopsy, disclosure of diagnosis, treatment of Alzheimer's disease, and counselling and support for caregivers were all revised when compared with the previous EFNS guideline. New recommendations were added for the treatment of vascular dementia, Parkinson's disease dementia, and dementia with Lewy bodies, for monitoring treatment, for treatment of behavioural and psychological symptoms in dementia, and for legal issues. The specialist physician plays an important role together with primary care physicians in the multidisciplinary dementia teams, which have been established throughout Europe. This guideline may contribute to the definition of the role of the specialist physician in providing dementia health care.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>G. Waldemar</name><affiliations><json:string>Memory Disorders Research Group, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Denmark</json:string></affiliations></json:item><json:item><name>B. Dubois</name><affiliations><json:string>Department of Neurology and Dementia Research Center, Hopital de la Salpetriere, Paris, France</json:string></affiliations></json:item><json:item><name>M. Emre</name><affiliations><json:string>Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey</json:string></affiliations></json:item><json:item><name>J. Georges</name><affiliations><json:string>Alzheimer Europe, Luxembourg</json:string></affiliations></json:item><json:item><name>I. G. McKeith</name><affiliations><json:string>Institute for Ageing and Health, Newcastle General Hospital, Newcastle upon Tyne, UK</json:string></affiliations></json:item><json:item><name>M. Rossor</name><affiliations><json:string>Dementia Research Centre, Institute of Neurology, University College London, London, UK</json:string></affiliations></json:item><json:item><name>P. Scheltens</name><affiliations><json:string>Department of Neurology and Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands</json:string></affiliations></json:item><json:item><name>P. Tariska</name><affiliations><json:string>Department of Neurology, National Institute of Psychiatry and Neurology, Budapest, Hungary</json:string></affiliations></json:item><json:item><name>B. 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It covers major aspects of diagnostic evaluation and treatment, with particular emphasis on the type of patient often referred to the specialist physician. The main focus is Alzheimer's disease, but many of the recommendations apply to dementia disorders in general. The task force working group considered and classified evidence from original research reports, meta‐analysis, and systematic reviews, published before January 2006. The evidence was classified and consensus recommendations graded according to the EFNS guidance. Where there was a lack of evidence, but clear consensus, good practice points were provided. The recommendations for clinical diagnosis, blood tests, neuroimaging, electroencephalography (EEG), cerebrospinal fluid (CSF) analysis, genetic testing, tissue biopsy, disclosure of diagnosis, treatment of Alzheimer's disease, and counselling and support for caregivers were all revised when compared with the previous EFNS guideline. New recommendations were added for the treatment of vascular dementia, Parkinson's disease dementia, and dementia with Lewy bodies, for monitoring treatment, for treatment of behavioural and psychological symptoms in dementia, and for legal issues. The specialist physician plays an important role together with primary care physicians in the multidisciplinary dementia teams, which have been established throughout Europe. 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It covers major aspects of diagnostic evaluation and treatment, with particular emphasis on the type of patient often referred to the specialist physician. The main focus is Alzheimer's disease, but many of the recommendations apply to dementia disorders in general. The task force working group considered and classified evidence from original research reports, meta‐analysis, and systematic reviews, published before January 2006. The evidence was classified and consensus recommendations graded according to the EFNS guidance. Where there was a lack of evidence, but clear consensus, good practice points were provided. The recommendations for clinical diagnosis, blood tests, neuroimaging, electroencephalography (EEG), cerebrospinal fluid (CSF) analysis, genetic testing, tissue biopsy, disclosure of diagnosis, treatment of Alzheimer's disease, and counselling and support for caregivers were all revised when compared with the previous EFNS guideline. New recommendations were added for the treatment of vascular dementia, Parkinson's disease dementia, and dementia with Lewy bodies, for monitoring treatment, for treatment of behavioural and psychological symptoms in dementia, and for legal issues. The specialist physician plays an important role together with primary care physicians in the multidisciplinary dementia teams, which have been established throughout Europe. This guideline may contribute to the definition of the role of the specialist physician in providing dementia health care.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>Alzheimer's disease</term></item><item><term>dementia</term></item><item><term>diagnosis</term></item><item><term>guideline</term></item><item><term>management</term></item><item><term>treatment</term></item><item><term>vascular dementia</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2007-01">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/3B1BE630622933F329404DBB92A4762AB953C302/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Publishing Ltd</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1468-1331</doi><issn type="print">1351-5101</issn><issn type="electronic">1468-1331</issn><idGroup><id type="product" value="ENE"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="EUROPEAN JOURNAL OF NEUROLOGY">European Journal of Neurology</title></titleGroup></publicationMeta><publicationMeta level="part" position="01001"><doi origin="wiley">10.1111/ene.2007.14.issue-1</doi><numberingGroup><numbering type="journalVolume" number="14">14</numbering><numbering type="journalIssue" number="1">1</numbering></numberingGroup><coverDate startDate="2007-01">January 2007</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="25" status="forIssue"><doi origin="wiley">10.1111/j.1468-1331.2006.01605.x</doi><idGroup><id type="unit" value="ENE1605"></id></idGroup><countGroup><count type="pageTotal" number="26"></count></countGroup><titleGroup><title type="tocHeading1">EFNS Task Force/CME Article</title></titleGroup><eventGroup><event type="firstOnline" date="2007-01-09"></event><event type="publishedOnlineFinalForm" date="2007-01-09"></event><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:2.3.5 mode:FullText source:FullText result:FullText" date="2010-04-07"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-24"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-16"></event></eventGroup><numberingGroup><numbering type="pageFirst">e1</numbering><numbering type="pageLast">e26</numbering></numberingGroup><correspondenceTo>Gunhild Waldemar, Professor, MD, DMSc; Department of Neurology, Copenhagen University Hospital, Rigshospitalet, section 6702, 9 Blegdamsvej, DK‐2100 Copenhagen, Denmark (tel.: +45 35452580; fax: +45 35452446; e‐mail: <email>gunhild.waldemar@rh.hosp.dk</email>).</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:ENE.ENE1605.pdf"></link></linkGroup></publicationMeta><contentMeta><unparsedEditorialHistory>Received 27 May 2006 Accepted 26 June 2006</unparsedEditorialHistory><countGroup><count type="figureTotal" number="0"></count><count type="tableTotal" number="0"></count></countGroup><titleGroup><title type="main">Recommendations for the diagnosis and management of Alzheimer's disease and other disorders associated with dementia: EFNS guideline</title><title type="shortAuthors">G. Waldemar <i>et al.</i></title><title type="short">EFNS dementia guideline</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1"><personName><givenNames>G.</givenNames><familyName>Waldemar</familyName></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#a2"><personName><givenNames>B.</givenNames><familyName>Dubois</familyName></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#a3"><personName><givenNames>M.</givenNames><familyName>Emre</familyName></personName></creator><creator creatorRole="author" xml:id="cr4" affiliationRef="#a4"><personName><givenNames>J.</givenNames><familyName>Georges</familyName></personName></creator><creator creatorRole="author" xml:id="cr5" affiliationRef="#a5"><personName><givenNames>I. G.</givenNames><familyName>McKeith</familyName></personName></creator><creator creatorRole="author" xml:id="cr6" affiliationRef="#a6"><personName><givenNames>M.</givenNames><familyName>Rossor</familyName></personName></creator><creator creatorRole="author" xml:id="cr7" affiliationRef="#a7"><personName><givenNames>P.</givenNames><familyName>Scheltens</familyName></personName></creator><creator creatorRole="author" xml:id="cr8" affiliationRef="#a8"><personName><givenNames>P.</givenNames><familyName>Tariska</familyName></personName></creator><creator creatorRole="author" xml:id="cr9" affiliationRef="#a9"><personName><givenNames>B.</givenNames><familyName>Winblad</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="a1" countryCode="DK"><unparsedAffiliation>Memory Disorders Research Group, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Denmark</unparsedAffiliation></affiliation><affiliation xml:id="a2" countryCode="FR"><unparsedAffiliation>Department of Neurology and Dementia Research Center, Hopital de la Salpetriere, Paris, France</unparsedAffiliation></affiliation><affiliation xml:id="a3" countryCode="TR"><unparsedAffiliation>Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey</unparsedAffiliation></affiliation><affiliation xml:id="a4" countryCode="LU"><unparsedAffiliation>Alzheimer Europe, Luxembourg</unparsedAffiliation></affiliation><affiliation xml:id="a5" countryCode="GB"><unparsedAffiliation>Institute for Ageing and Health, Newcastle General Hospital, Newcastle upon Tyne, UK</unparsedAffiliation></affiliation><affiliation xml:id="a6" countryCode="GB"><unparsedAffiliation>Dementia Research Centre, Institute of Neurology, University College London, London, UK</unparsedAffiliation></affiliation><affiliation xml:id="a7" countryCode="NL"><unparsedAffiliation>Department of Neurology and Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands</unparsedAffiliation></affiliation><affiliation xml:id="a8" countryCode="HU"><unparsedAffiliation>Department of Neurology, National Institute of Psychiatry and Neurology, Budapest, Hungary</unparsedAffiliation></affiliation><affiliation xml:id="a9" countryCode="SE"><unparsedAffiliation>Department of Geriatric Medicine, Karolinska University Hospital, Huddinge, Sweden</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en"><keyword xml:id="k1">Alzheimer's disease</keyword><keyword xml:id="k2">dementia</keyword><keyword xml:id="k3">diagnosis</keyword><keyword xml:id="k4">guideline</keyword><keyword xml:id="k5">management</keyword><keyword xml:id="k6">treatment</keyword><keyword xml:id="k7">vascular dementia</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><p>The aim of this international guideline on dementia was to present a peer‐reviewed evidence‐based statement for the guidance of practice for clinical neurologists, geriatricians, psychiatrists, and other specialist physicians responsible for the care of patients with dementia. It covers major aspects of diagnostic evaluation and treatment, with particular emphasis on the type of patient often referred to the specialist physician. The main focus is Alzheimer's disease, but many of the recommendations apply to dementia disorders in general. The task force working group considered and classified evidence from original research reports, meta‐analysis, and systematic reviews, published before January 2006. The evidence was classified and consensus recommendations graded according to the EFNS guidance. Where there was a lack of evidence, but clear consensus, good practice points were provided. The recommendations for clinical diagnosis, blood tests, neuroimaging, electroencephalography (EEG), cerebrospinal fluid (CSF) analysis, genetic testing, tissue biopsy, disclosure of diagnosis, treatment of Alzheimer's disease, and counselling and support for caregivers were all revised when compared with the previous EFNS guideline. New recommendations were added for the treatment of vascular dementia, Parkinson's disease dementia, and dementia with Lewy bodies, for monitoring treatment, for treatment of behavioural and psychological symptoms in dementia, and for legal issues. The specialist physician plays an important role together with primary care physicians in the multidisciplinary dementia teams, which have been established throughout Europe. This guideline may contribute to the definition of the role of the specialist physician in providing dementia health care.</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="artCateg-note" numbered="no"><p>This is a Continuing Medical Education paper and can be found with corresponding questions on the Internet at: <url href="http://www.blackwellpublishing.com/products/journals/ene/mcqs">http://www.blackwellpublishing.com/products/journals/ene/mcqs</url>. Certificates for correctly answering the questions will be issued by the EFNS.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Recommendations for the diagnosis and management of Alzheimer's disease and other disorders associated with dementia: EFNS guideline</title></titleInfo><titleInfo type="abbreviated"><title>EFNS dementia guideline</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Recommendations for the diagnosis and management of Alzheimer's disease and other disorders associated with dementia: EFNS guideline</title></titleInfo><name type="personal"><namePart type="given">G.</namePart><namePart type="family">Waldemar</namePart><affiliation>Memory Disorders Research Group, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Denmark</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B.</namePart><namePart type="family">Dubois</namePart><affiliation>Department of Neurology and Dementia Research Center, Hopital de la Salpetriere, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="family">Emre</namePart><affiliation>Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J.</namePart><namePart type="family">Georges</namePart><affiliation>Alzheimer Europe, Luxembourg</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">I. G.</namePart><namePart type="family">McKeith</namePart><affiliation>Institute for Ageing and Health, Newcastle General Hospital, Newcastle upon Tyne, UK</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="family">Rossor</namePart><affiliation>Dementia Research Centre, Institute of Neurology, University College London, London, UK</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P.</namePart><namePart type="family">Scheltens</namePart><affiliation>Department of Neurology and Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P.</namePart><namePart type="family">Tariska</namePart><affiliation>Department of Neurology, National Institute of Psychiatry and Neurology, Budapest, Hungary</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B.</namePart><namePart type="family">Winblad</namePart><affiliation>Department of Geriatric Medicine, Karolinska University Hospital, Huddinge, Sweden</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2007-01</dateIssued><edition>Received 27 May 2006 Accepted 26 June 2006</edition><copyrightDate encoding="w3cdtf">2007</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">The aim of this international guideline on dementia was to present a peer‐reviewed evidence‐based statement for the guidance of practice for clinical neurologists, geriatricians, psychiatrists, and other specialist physicians responsible for the care of patients with dementia. It covers major aspects of diagnostic evaluation and treatment, with particular emphasis on the type of patient often referred to the specialist physician. The main focus is Alzheimer's disease, but many of the recommendations apply to dementia disorders in general. The task force working group considered and classified evidence from original research reports, meta‐analysis, and systematic reviews, published before January 2006. The evidence was classified and consensus recommendations graded according to the EFNS guidance. Where there was a lack of evidence, but clear consensus, good practice points were provided. The recommendations for clinical diagnosis, blood tests, neuroimaging, electroencephalography (EEG), cerebrospinal fluid (CSF) analysis, genetic testing, tissue biopsy, disclosure of diagnosis, treatment of Alzheimer's disease, and counselling and support for caregivers were all revised when compared with the previous EFNS guideline. New recommendations were added for the treatment of vascular dementia, Parkinson's disease dementia, and dementia with Lewy bodies, for monitoring treatment, for treatment of behavioural and psychological symptoms in dementia, and for legal issues. The specialist physician plays an important role together with primary care physicians in the multidisciplinary dementia teams, which have been established throughout Europe. This guideline may contribute to the definition of the role of the specialist physician in providing dementia health care.</abstract><subject lang="en"><genre>Keywords</genre><topic>Alzheimer's disease</topic><topic>dementia</topic><topic>diagnosis</topic><topic>guideline</topic><topic>management</topic><topic>treatment</topic><topic>vascular dementia</topic></subject><relatedItem type="host"><titleInfo><title>European Journal of Neurology</title></titleInfo><genre type="Journal">journal</genre><identifier type="ISSN">1351-5101</identifier><identifier type="eISSN">1468-1331</identifier><identifier type="DOI">10.1111/(ISSN)1468-1331</identifier><identifier type="PublisherID">ENE</identifier><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>14</number></detail><detail type="issue"><caption>no.</caption><number>1</number></detail><extent unit="pages"><start>e1</start><end>e26</end><total>26</total></extent></part></relatedItem><identifier type="istex">3B1BE630622933F329404DBB92A4762AB953C302</identifier><identifier type="DOI">10.1111/j.1468-1331.2006.01605.x</identifier><identifier type="ArticleID">ENE1605</identifier><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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