Impulse control disorders and dopamine dysregulation in Parkinson’s disease: a broader conceptual framework
Identifieur interne : 002553 ( Main/Corpus ); précédent : 002552; suivant : 002554Impulse control disorders and dopamine dysregulation in Parkinson’s disease: a broader conceptual framework
Auteurs : D. Okai ; M. Samuel ; S. Askey-Jones ; A. S. David ; R. G. BrownSource :
- European Journal of Neurology [ 1351-5101 ] ; 2011-12.
English descriptors
- KwdEn :
Abstract
Background: Impulse control disorders (ICDs) and dopamine dysregulation syndrome (DDS) in Parkinson’s disease are motivation‐based behaviours that involve repetitive occurrences of impulsive and uncontrolled activity. Psychiatric classification is currently inconsistent and unclear. An accurate conceptualisation of these problems is important to guide research and treatment. Methods and Results: The review considers conceptual and methodological problems underlying the diagnosis of ICDs and the assessment of their severity. Whilst having features of obsessive–compulsive spectrum model, ICD‐5 may bring them together for the first time into a single category of behavioural addictions. Whilst matching clinical and biological evidence, any such psychiatric classification in Parkinson’s disease will remain complicated by the interactions of pathophysiology and medication and fail to capture the range of subthreshold but still clinically significant symptomatology. Conclusions: A non‐diagnostic, dimensional construct of disinhibitory psychopathology may be a useful tool to guide research and inform treatment. The role of dysphoria is suggested as a further important factor in driving some of these problem behaviours. This opens the opportunity for adjunctive psychological approaches in management.
Url:
DOI: 10.1111/j.1468-1331.2011.03432.x
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ISTEX:7F259BC58C5A60A317936EA84B5F5B5E2BC1D49ALe document en format XML
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Okai</name><affiliation><mods:affiliation>Section of Cognitive Psychiatry, Institute of Psychiatry, King’s College London, London</mods:affiliation></affiliation></author><author><name sortKey="Samuel, M" sort="Samuel, M" uniqKey="Samuel M" first="M." last="Samuel">M. Samuel</name><affiliation><mods:affiliation>Department of Neurology, King’s College Hospital, NHS Foundation Trust, King's Health Partners, London, and East Kent NHS Foundation Trust, Ashford, Kent</mods:affiliation></affiliation></author><author><name sortKey="Askey Ones, S" sort="Askey Ones, S" uniqKey="Askey Ones S" first="S." last="Askey-Jones">S. Askey-Jones</name><affiliation><mods:affiliation>Section of Cognitive Psychiatry, Institute of Psychiatry, King’s College London, London</mods:affiliation></affiliation></author><author><name sortKey="David, A S" sort="David, A S" uniqKey="David A" first="A. S." last="David">A. S. 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Psychiatric classification is currently inconsistent and unclear. An accurate conceptualisation of these problems is important to guide research and treatment. Methods and Results: The review considers conceptual and methodological problems underlying the diagnosis of ICDs and the assessment of their severity. Whilst having features of obsessive–compulsive spectrum model, ICD‐5 may bring them together for the first time into a single category of behavioural addictions. Whilst matching clinical and biological evidence, any such psychiatric classification in Parkinson’s disease will remain complicated by the interactions of pathophysiology and medication and fail to capture the range of subthreshold but still clinically significant symptomatology. Conclusions: A non‐diagnostic, dimensional construct of disinhibitory psychopathology may be a useful tool to guide research and inform treatment. The role of dysphoria is suggested as a further important factor in driving some of these problem behaviours. This opens the opportunity for adjunctive psychological approaches in management.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>D. Okai</name><affiliations><json:string>Section of Cognitive Psychiatry, Institute of Psychiatry, King’s College London, London</json:string></affiliations></json:item><json:item><name>M. Samuel</name><affiliations><json:string>Department of Neurology, King’s College Hospital, NHS Foundation Trust, King's Health Partners, London, and East Kent NHS Foundation Trust, Ashford, Kent</json:string></affiliations></json:item><json:item><name>S. Askey‐Jones</name><affiliations><json:string>Section of Cognitive Psychiatry, Institute of Psychiatry, King’s College London, London</json:string></affiliations></json:item><json:item><name>A. S. 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Brown</name><affiliations><json:string>Department of Psychology, Institute of Psychiatry, King’s College London, London, UK</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>addiction</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>diagnosis</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>disinhibition</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>dysphoria</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>gambling</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>hypersexuality</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>severity</value></json:item></subject><articleId><json:string>ENE3432</json:string></articleId><language><json:string>eng</json:string></language><abstract>Background: Impulse control disorders (ICDs) and dopamine dysregulation syndrome (DDS) in Parkinson’s disease are motivation‐based behaviours that involve repetitive occurrences of impulsive and uncontrolled activity. Psychiatric classification is currently inconsistent and unclear. An accurate conceptualisation of these problems is important to guide research and treatment. Methods and Results: The review considers conceptual and methodological problems underlying the diagnosis of ICDs and the assessment of their severity. Whilst having features of obsessive–compulsive spectrum model, ICD‐5 may bring them together for the first time into a single category of behavioural addictions. Whilst matching clinical and biological evidence, any such psychiatric classification in Parkinson’s disease will remain complicated by the interactions of pathophysiology and medication and fail to capture the range of subthreshold but still clinically significant symptomatology. Conclusions: A non‐diagnostic, dimensional construct of disinhibitory psychopathology may be a useful tool to guide research and inform treatment. The role of dysphoria is suggested as a further important factor in driving some of these problem behaviours. 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S.</forename><surname>David</surname></persName><affiliation>Section of Cognitive Psychiatry, Institute of Psychiatry, King’s College London, London</affiliation></author><author><persName><forename type="first">R. 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Psychiatric classification is currently inconsistent and unclear. An accurate conceptualisation of these problems is important to guide research and treatment. Methods and Results: The review considers conceptual and methodological problems underlying the diagnosis of ICDs and the assessment of their severity. Whilst having features of obsessive–compulsive spectrum model, ICD‐5 may bring them together for the first time into a single category of behavioural addictions. Whilst matching clinical and biological evidence, any such psychiatric classification in Parkinson’s disease will remain complicated by the interactions of pathophysiology and medication and fail to capture the range of subthreshold but still clinically significant symptomatology. Conclusions: A non‐diagnostic, dimensional construct of disinhibitory psychopathology may be a useful tool to guide research and inform treatment. The role of dysphoria is suggested as a further important factor in driving some of these problem behaviours. This opens the opportunity for adjunctive psychological approaches in management.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>addiction</term></item><item><term>diagnosis</term></item><item><term>disinhibition</term></item><item><term>dysphoria</term></item><item><term>gambling</term></item><item><term>hypersexuality</term></item><item><term>severity</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>article category</head><item><term>REVIEW ARTICLE</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2011-12">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/7F259BC58C5A60A317936EA84B5F5B5E2BC1D49A/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Publishing Ltd</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1468-1331</doi><issn type="print">1351-5101</issn><issn type="electronic">1468-1331</issn><idGroup><id type="product" value="ENE"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="EUROPEAN JOURNAL OF NEUROLOGY">European Journal of Neurology</title></titleGroup></publicationMeta><publicationMeta level="part" position="12112"><doi origin="wiley">10.1111/ene.2011.18.issue-12</doi><numberingGroup><numbering type="journalVolume" number="18">18</numbering><numbering type="journalIssue" number="12">12</numbering></numberingGroup><coverDate startDate="2011-12">December 2011</coverDate></publicationMeta><publicationMeta level="unit" type="reviewArticle" position="3" status="forIssue"><doi origin="wiley">10.1111/j.1468-1331.2011.03432.x</doi><idGroup><id type="unit" value="ENE3432"></id></idGroup><countGroup><count type="pageTotal" number="5"></count></countGroup><titleGroup><title type="tocHeading1">Review Article</title><title type="articleCategory">REVIEW ARTICLE</title></titleGroup><copyright>© 2011 The Author(s). European Journal of Neurology © 2011 EFNS</copyright><eventGroup><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:3.0 mode:FullText" date="2011-11-18"></event><event type="publishedOnlineEarlyUnpaginated" date="2011-05-25"></event><event type="firstOnline" date="2011-05-25"></event><event type="publishedOnlineFinalForm" date="2011-11-18"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-24"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-16"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="1379">1379</numbering><numbering type="pageLast" number="1383">1383</numbering></numberingGroup><correspondenceTo>Prof. R. G. Brown, Department of Psychology, Institute of Psychiatry PO77, King’s College London, London, SE5 8AF, UK (tel.: +44/0 20 7848 0773; fax: +44/0 20 7848 5006; e‐mail: <email>richard.g.brown@kcl.ac.uk</email>).</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:ENE.ENE3432.pdf"></link></linkGroup></publicationMeta><contentMeta><unparsedEditorialHistory>Received 7 December 2010 Accepted 7 April 2011</unparsedEditorialHistory><countGroup><count type="figureTotal" number="0"></count><count type="tableTotal" number="1"></count></countGroup><titleGroup><title type="main">Impulse control disorders and dopamine dysregulation in Parkinson’s disease: a broader conceptual framework</title><title type="shortAuthors">D. Okai <i>et al.</i></title><title type="short">Impulse control disorder in Parkinson’s disease</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1"><personName><givenNames>D.</givenNames><familyName>Okai</familyName></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#a2"><personName><givenNames>M.</givenNames><familyName>Samuel</familyName></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#a1"><personName><givenNames>S.</givenNames><familyName>Askey‐Jones</familyName></personName></creator><creator creatorRole="author" xml:id="cr4" affiliationRef="#a1"><personName><givenNames>A. S.</givenNames><familyName>David</familyName></personName></creator><creator creatorRole="author" xml:id="cr5" affiliationRef="#a3"><personName><givenNames>R. G.</givenNames><familyName>Brown</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="a1"><unparsedAffiliation>Section of Cognitive Psychiatry, Institute of Psychiatry, King’s College London, London</unparsedAffiliation></affiliation><affiliation xml:id="a2"><unparsedAffiliation>Department of Neurology, King’s College Hospital, NHS Foundation Trust, King's Health Partners, London, and East Kent NHS Foundation Trust, Ashford, Kent</unparsedAffiliation></affiliation><affiliation xml:id="a3" countryCode="GB"><unparsedAffiliation>Department of Psychology, Institute of Psychiatry, King’s College London, London, UK</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en"><keyword xml:id="k1">addiction</keyword><keyword xml:id="k2">diagnosis</keyword><keyword xml:id="k3">disinhibition</keyword><keyword xml:id="k4">dysphoria</keyword><keyword xml:id="k5">gambling</keyword><keyword xml:id="k6">hypersexuality</keyword><keyword xml:id="k7">severity</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><p><b>Background: </b> Impulse control disorders (ICDs) and dopamine dysregulation syndrome (DDS) in Parkinson’s disease are motivation‐based behaviours that involve repetitive occurrences of impulsive and uncontrolled activity. Psychiatric classification is currently inconsistent and unclear. An accurate conceptualisation of these problems is important to guide research and treatment.</p><p><b>Methods and Results: </b> The review considers conceptual and methodological problems underlying the diagnosis of ICDs and the assessment of their severity. Whilst having features of obsessive–compulsive spectrum model, ICD‐5 may bring them together for the first time into a single category of behavioural addictions. Whilst matching clinical and biological evidence, any such psychiatric classification in Parkinson’s disease will remain complicated by the interactions of pathophysiology and medication and fail to capture the range of subthreshold but still clinically significant symptomatology.</p><p><b>Conclusions: </b> A non‐diagnostic, dimensional construct of disinhibitory psychopathology may be a useful tool to guide research and inform treatment. The role of dysphoria is suggested as a further important factor in driving some of these problem behaviours. This opens the opportunity for adjunctive psychological approaches in management.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Impulse control disorders and dopamine dysregulation in Parkinson’s disease: a broader conceptual framework</title></titleInfo><titleInfo type="abbreviated"><title>Impulse control disorder in Parkinson’s disease</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Impulse control disorders and dopamine dysregulation in Parkinson’s disease: a broader conceptual framework</title></titleInfo><name type="personal"><namePart type="given">D.</namePart><namePart type="family">Okai</namePart><affiliation>Section of Cognitive Psychiatry, Institute of Psychiatry, King’s College London, London</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="family">Samuel</namePart><affiliation>Department of Neurology, King’s College Hospital, NHS Foundation Trust, King's Health Partners, London, and East Kent NHS Foundation Trust, Ashford, Kent</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S.</namePart><namePart type="family">Askey‐Jones</namePart><affiliation>Section of Cognitive Psychiatry, Institute of Psychiatry, King’s College London, London</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A. S.</namePart><namePart type="family">David</namePart><affiliation>Section of Cognitive Psychiatry, Institute of Psychiatry, King’s College London, London</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R. G.</namePart><namePart type="family">Brown</namePart><affiliation>Department of Psychology, Institute of Psychiatry, King’s College London, London, UK</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="review-article" displayLabel="reviewArticle"></genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2011-12</dateIssued><edition>Received 7 December 2010 Accepted 7 April 2011</edition><copyrightDate encoding="w3cdtf">2011</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="tables">1</extent></physicalDescription><abstract lang="en">Background: Impulse control disorders (ICDs) and dopamine dysregulation syndrome (DDS) in Parkinson’s disease are motivation‐based behaviours that involve repetitive occurrences of impulsive and uncontrolled activity. Psychiatric classification is currently inconsistent and unclear. An accurate conceptualisation of these problems is important to guide research and treatment. Methods and Results: The review considers conceptual and methodological problems underlying the diagnosis of ICDs and the assessment of their severity. Whilst having features of obsessive–compulsive spectrum model, ICD‐5 may bring them together for the first time into a single category of behavioural addictions. Whilst matching clinical and biological evidence, any such psychiatric classification in Parkinson’s disease will remain complicated by the interactions of pathophysiology and medication and fail to capture the range of subthreshold but still clinically significant symptomatology. Conclusions: A non‐diagnostic, dimensional construct of disinhibitory psychopathology may be a useful tool to guide research and inform treatment. The role of dysphoria is suggested as a further important factor in driving some of these problem behaviours. This opens the opportunity for adjunctive psychological approaches in management.</abstract><subject lang="en"><genre>Keywords</genre><topic>addiction</topic><topic>diagnosis</topic><topic>disinhibition</topic><topic>dysphoria</topic><topic>gambling</topic><topic>hypersexuality</topic><topic>severity</topic></subject><relatedItem type="host"><titleInfo><title>European Journal of Neurology</title></titleInfo><genre type="Journal">journal</genre><subject><genre>article category</genre><topic>REVIEW ARTICLE</topic></subject><identifier type="ISSN">1351-5101</identifier><identifier type="eISSN">1468-1331</identifier><identifier type="DOI">10.1111/(ISSN)1468-1331</identifier><identifier type="PublisherID">ENE</identifier><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>18</number></detail><detail type="issue"><caption>no.</caption><number>12</number></detail><extent unit="pages"><start>1379</start><end>1383</end><total>5</total></extent></part></relatedItem><identifier type="istex">7F259BC58C5A60A317936EA84B5F5B5E2BC1D49A</identifier><identifier type="DOI">10.1111/j.1468-1331.2011.03432.x</identifier><identifier type="ArticleID">ENE3432</identifier><accessCondition type="use and reproduction" contentType="copyright">© 2011 The Author(s). 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