Arbitrary visuomotor mapping during object manipulation in Parkinson's disease
Identifieur interne : 001E08 ( Main/Corpus ); précédent : 001E07; suivant : 001E09Arbitrary visuomotor mapping during object manipulation in Parkinson's disease
Auteurs : Dennis A. Nowak ; Mitra Ameli ; Friederike Kemper ; Anna-Sophia Sarfeld ; Djamel Bensmail ; Jürgen Konczak ; Gereon R. FinkSource :
- Movement Disorders [ 0885-3185 ] ; 2009-10-15.
English descriptors
Abstract
The objective of this study is to investigate whether subjects with Parkinson's disease are able to use arbitrary color cues linked to the mass of an object to be lifted allowing for the predictive selection of appropriate grip forces. Fourteen patients with Parkinson's disease used a precision grip to lift two objects of different masses (400 and 600 g) in random order. In a “no cue” condition, a noninformative neutral visual stimulus was presented before each lift, thereby not allowing any judgement about which mass to be lifted. In a “cue” condition an arbitrary color cue provided advance information about which of the two masses patients would have to lift in the subsequent trial. Patients performed the conditions with either hand and by both on and off drugs. In the “no cue” trials patients scaled the predictive grip force output according to the perceived mass of the preceding lift. In the “cue” experiment patients scaled grip force in a predictive manner to mass based on the provided color cues. The ability of arbitrary visuomotor mapping was evident at either hand and not influenced by medication on/off. The precision of arbitrary visuomotor mapping correlated negatively with age, but not with disease duration, severity of motor disability on and off drug, severity of cognitive impairment on and off drug, or the amount of levodopa equivalent daily dosage of dopaminergic drugs. These data imply that Parkinson's disease does not preclude the ability of visuomotor mapping in the grip‐lift task. © 2009 Movement Disorder Society
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DOI: 10.1002/mds.22543
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ISTEX:D60E8586DA620D06BF5FB2E159F73050E4BA3C69Le document en format XML
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Nowak MD, PhD</name><affiliations><json:string>Department of Neurology, University of Cologne, Cologne, Germany</json:string><json:string>Institute of Neuroscience and Medicine (INM‐3), Cognitive Neurology, Research Centre Jülich, Jülich, Germany</json:string><json:string>Human Sensorimotor Control Laboratory, University of Minnesota, Minneapolis, Minnesota</json:string></affiliations></json:item><json:item><name>Mitra Ameli MD</name><affiliations><json:string>Department of Neurology, University of Cologne, Cologne, Germany</json:string></affiliations></json:item><json:item><name>Friederike Kemper MD</name><affiliations><json:string>Department of Neurology, University of Cologne, Cologne, Germany</json:string></affiliations></json:item><json:item><name>Anna‐Sophia Sarfeld MS</name><affiliations><json:string>Department of Neurology, University of Cologne, Cologne, Germany</json:string></affiliations></json:item><json:item><name>Djamel Bensmail MD</name><affiliations><json:string>Department of Neurology, University of Cologne, Cologne, Germany</json:string><json:string>Department of Physical Medicine and Rehabilitation, Hôpital R. 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Fourteen patients with Parkinson's disease used a precision grip to lift two objects of different masses (400 and 600 g) in random order. In a “no cue” condition, a noninformative neutral visual stimulus was presented before each lift, thereby not allowing any judgement about which mass to be lifted. In a “cue” condition an arbitrary color cue provided advance information about which of the two masses patients would have to lift in the subsequent trial. Patients performed the conditions with either hand and by both on and off drugs. In the “no cue” trials patients scaled the predictive grip force output according to the perceived mass of the preceding lift. In the “cue” experiment patients scaled grip force in a predictive manner to mass based on the provided color cues. The ability of arbitrary visuomotor mapping was evident at either hand and not influenced by medication on/off. The precision of arbitrary visuomotor mapping correlated negatively with age, but not with disease duration, severity of motor disability on and off drug, severity of cognitive impairment on and off drug, or the amount of levodopa equivalent daily dosage of dopaminergic drugs. 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The precision of arbitrary visuomotor mapping correlated negatively with age, but not with disease duration, severity of motor disability on and off drug, severity of cognitive impairment on and off drug, or the amount of levodopa equivalent daily dosage of dopaminergic drugs. These data imply that Parkinson's disease does not preclude the ability of visuomotor mapping in the grip‐lift task. © 2009 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>grip force</term></item><item><term>lift force</term></item><item><term>conditional motor learning</term></item><item><term>basal ganglia</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>article category</head><item><term>Research Article</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2009-01-12">Received</change><change when="2009-02-23">Registration</change><change when="2009-10-15">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/D60E8586DA620D06BF5FB2E159F73050E4BA3C69/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="short">Mov. 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Poincaré, Garches, AP‐HP, University of Versailles Saint‐Quentin, France</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">grip force</keyword><keyword xml:id="kwd2">lift force</keyword><keyword xml:id="kwd3">conditional motor learning</keyword><keyword xml:id="kwd4">basal ganglia</keyword></keywordGroup><fundingInfo><fundingAgency>Deutsche Forschungsgemeinschaft</fundingAgency><fundingNumber>DFG NO737/4‐1</fundingNumber></fundingInfo><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>The objective of this study is to investigate whether subjects with Parkinson's disease are able to use arbitrary color cues linked to the mass of an object to be lifted allowing for the predictive selection of appropriate grip forces. Fourteen patients with Parkinson's disease used a precision grip to lift two objects of different masses (400 and 600 g) in random order. In a “no cue” condition, a noninformative neutral visual stimulus was presented before each lift, thereby not allowing any judgement about which mass to be lifted. In a “cue” condition an arbitrary color cue provided advance information about which of the two masses patients would have to lift in the subsequent trial. Patients performed the conditions with either hand and by both on and off drugs. In the “no cue” trials patients scaled the predictive grip force output according to the perceived mass of the preceding lift. In the “cue” experiment patients scaled grip force in a predictive manner to mass based on the provided color cues. The ability of arbitrary visuomotor mapping was evident at either hand and not influenced by medication on/off. The precision of arbitrary visuomotor mapping correlated negatively with age, but not with disease duration, severity of motor disability on and off drug, severity of cognitive impairment on and off drug, or the amount of levodopa equivalent daily dosage of dopaminergic drugs. These data imply that Parkinson's disease does not preclude the ability of visuomotor mapping in the grip‐lift task. © 2009 Movement Disorder Society</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="fn3"><p>Potential conflict of interest: None reported.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Arbitrary visuomotor mapping during object manipulation in Parkinson's disease</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Arbitrary Visuomotor Mapping in Parkinson's Disease</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Arbitrary visuomotor mapping during object manipulation in Parkinson's disease</title></titleInfo><name type="personal"><namePart type="given">Dennis A.</namePart><namePart type="family">Nowak</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department of Neurology, University of Cologne, Cologne, Germany</affiliation><affiliation>Institute of Neuroscience and Medicine (INM‐3), Cognitive Neurology, Research Centre Jülich, Jülich, Germany</affiliation><affiliation>Human Sensorimotor Control Laboratory, University of Minnesota, Minneapolis, Minnesota</affiliation><description>Correspondence: Klinik Kipfenberg, Neurochirurgische und Neurologische Fachklinik, Kindinger Strasse 13, D‐85110 Kipfenberg, Germany</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Mitra</namePart><namePart type="family">Ameli</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University of Cologne, Cologne, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Friederike</namePart><namePart type="family">Kemper</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University of Cologne, Cologne, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Anna‐Sophia</namePart><namePart type="family">Sarfeld</namePart><namePart type="termsOfAddress">MS</namePart><affiliation>Department of Neurology, University of Cologne, Cologne, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Djamel</namePart><namePart type="family">Bensmail</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University of Cologne, Cologne, Germany</affiliation><affiliation>Department of Physical Medicine and Rehabilitation, Hôpital R. Poincaré, Garches, AP‐HP, University of Versailles Saint‐Quentin, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jürgen</namePart><namePart type="family">Konczak</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Human Sensorimotor Control Laboratory, University of Minnesota, Minneapolis, Minnesota</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Gereon R.</namePart><namePart type="family">Fink</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department of Neurology, University of Cologne, Cologne, Germany</affiliation><affiliation>Institute of Neuroscience and Medicine (INM‐3), Cognitive Neurology, Research Centre Jülich, Jülich, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2009-10-15</dateIssued><dateCaptured encoding="w3cdtf">2009-01-12</dateCaptured><dateValid encoding="w3cdtf">2009-02-23</dateValid><copyrightDate encoding="w3cdtf">2009</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">2</extent><extent unit="tables">2</extent><extent unit="references">32</extent><extent unit="words">6408</extent></physicalDescription><abstract lang="en">The objective of this study is to investigate whether subjects with Parkinson's disease are able to use arbitrary color cues linked to the mass of an object to be lifted allowing for the predictive selection of appropriate grip forces. Fourteen patients with Parkinson's disease used a precision grip to lift two objects of different masses (400 and 600 g) in random order. In a “no cue” condition, a noninformative neutral visual stimulus was presented before each lift, thereby not allowing any judgement about which mass to be lifted. In a “cue” condition an arbitrary color cue provided advance information about which of the two masses patients would have to lift in the subsequent trial. Patients performed the conditions with either hand and by both on and off drugs. In the “no cue” trials patients scaled the predictive grip force output according to the perceived mass of the preceding lift. In the “cue” experiment patients scaled grip force in a predictive manner to mass based on the provided color cues. The ability of arbitrary visuomotor mapping was evident at either hand and not influenced by medication on/off. The precision of arbitrary visuomotor mapping correlated negatively with age, but not with disease duration, severity of motor disability on and off drug, severity of cognitive impairment on and off drug, or the amount of levodopa equivalent daily dosage of dopaminergic drugs. These data imply that Parkinson's disease does not preclude the ability of visuomotor mapping in the grip‐lift task. © 2009 Movement Disorder Society</abstract><note type="content">*Potential conflict of interest: None reported.</note><note type="funding">Deutsche Forschungsgemeinschaft - No. DFG NO737/4‐1; </note><subject lang="en"><genre>Keywords</genre><topic>grip force</topic><topic>lift force</topic><topic>conditional motor learning</topic><topic>basal ganglia</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><genre type="Journal">journal</genre><subject><genre>article category</genre><topic>Research Article</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>24</number></detail><detail type="issue"><caption>no.</caption><number>13</number></detail><extent unit="pages"><start>1925</start><end>1933</end><total>9</total></extent></part></relatedItem><identifier type="istex">D60E8586DA620D06BF5FB2E159F73050E4BA3C69</identifier><identifier type="DOI">10.1002/mds.22543</identifier><identifier type="ArticleID">MDS22543</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2009 Movement Disorder Society</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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