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What is the functional significance of nondominant arm tremor in essential tremor?

Identifieur interne : 001B95 ( Main/Corpus ); précédent : 001B94; suivant : 001B96

What is the functional significance of nondominant arm tremor in essential tremor?

Auteurs : Elan D. Louis ; Marina Gerbin ; Mary M. Mullaney

Source :

RBID : ISTEX:E9F8FF8F2AD3605A6897C1A8AD7BB47D8980E2CF

English descriptors

Abstract

Tremor in the dominant arm is often the focus of clinical attention in essential tremor (ET) yet many daily activities require both arms. The functional relevance of nondominant arm tremor has rarely been studied. In 181 right‐handed patients with ET, action tremor in each arm was rated using a clinical rating scale. Tremor disability was self‐reported and a performance‐based test of function was administered. Independently of tremor on the right, greater tremor severity on the left was associated with greater self‐reported disability (P = 0.02) and greater performance‐based dysfunction (P < 0.001). In 5.0% of patients, tremor was largely restricted to the nondominant arm. Nondominant arm tremor, independent of dominant arm tremor, had a significant functional correlate, contributing to both greater perceived and greater observable functional difficulty. In 5% of patients, tremor in the nondominant arm was the likely motivator for seeking care, which is another indication of its functional significance. © 2010 Movement Disorder Society.

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DOI: 10.1002/mds.23284

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= 0.02) and greater performance‐based dysfunction (
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< 0.001). In 5.0% of patients, tremor was largely restricted to the nondominant arm. Nondominant arm tremor, independent of dominant arm tremor, had a significant functional correlate, contributing to both greater perceived and greater observable functional difficulty. In 5% of patients, tremor in the nondominant arm was the likely motivator for seeking care, which is another indication of its functional significance. © 2010 Movement Disorder Society.</p>
</abstract>
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<noteGroup>
<note xml:id="fn3">
<p>Potential conflict of interest: The authors report no conflicts of interest.</p>
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<title>What is the functional significance of nondominant arm tremor in essential tremor?</title>
</titleInfo>
<titleInfo type="abbreviated" lang="en">
<title>Nondominant Arm Tremor in Essential Tremor</title>
</titleInfo>
<titleInfo type="alternative" contentType="CDATA" lang="en">
<title>What is the functional significance of nondominant arm tremor in essential tremor?</title>
</titleInfo>
<name type="personal">
<namePart type="given">Elan D.</namePart>
<namePart type="family">Louis</namePart>
<namePart type="termsOfAddress">MD, MSc</namePart>
<affiliation>GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York, USA</affiliation>
<affiliation>Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York, USA</affiliation>
<affiliation>Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, USA</affiliation>
<affiliation>Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA</affiliation>
<description>Correspondence: Unit 198, Neurological Institute, 710 West 168th Street, New York, NY, 10032, USA</description>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Marina</namePart>
<namePart type="family">Gerbin</namePart>
<namePart type="termsOfAddress">MPH</namePart>
<affiliation>GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York, USA</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Mary M.</namePart>
<namePart type="family">Mullaney</namePart>
<namePart type="termsOfAddress">MS</namePart>
<affiliation>GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York, USA</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
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<publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<place>
<placeTerm type="text">Hoboken</placeTerm>
</place>
<dateIssued encoding="w3cdtf">2010-11-15</dateIssued>
<dateCaptured encoding="w3cdtf">2010-03-09</dateCaptured>
<dateValid encoding="w3cdtf">2010-05-10</dateValid>
<copyrightDate encoding="w3cdtf">2010</copyrightDate>
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<languageTerm type="code" authority="iso639-2b">eng</languageTerm>
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<abstract lang="en">Tremor in the dominant arm is often the focus of clinical attention in essential tremor (ET) yet many daily activities require both arms. The functional relevance of nondominant arm tremor has rarely been studied. In 181 right‐handed patients with ET, action tremor in each arm was rated using a clinical rating scale. Tremor disability was self‐reported and a performance‐based test of function was administered. Independently of tremor on the right, greater tremor severity on the left was associated with greater self‐reported disability (P = 0.02) and greater performance‐based dysfunction (P < 0.001). In 5.0% of patients, tremor was largely restricted to the nondominant arm. Nondominant arm tremor, independent of dominant arm tremor, had a significant functional correlate, contributing to both greater perceived and greater observable functional difficulty. In 5% of patients, tremor in the nondominant arm was the likely motivator for seeking care, which is another indication of its functional significance. © 2010 Movement Disorder Society.</abstract>
<note type="content">*Potential conflict of interest: The authors report no conflicts of interest.</note>
<note type="funding">National Institutes of Health (Bethesda, MD) - No. R01 NS39422; No. R01 NS42859; </note>
<subject lang="en">
<genre>Keywords</genre>
<topic>essential tremor</topic>
<topic>clinical</topic>
<topic>function</topic>
<topic>disability</topic>
</subject>
<relatedItem type="host">
<titleInfo>
<title>Movement Disorders</title>
</titleInfo>
<titleInfo type="abbreviated">
<title>Mov. Disord.</title>
</titleInfo>
<genre type="Journal">journal</genre>
<subject>
<genre>article category</genre>
<topic>Brief Report</topic>
</subject>
<identifier type="ISSN">0885-3185</identifier>
<identifier type="eISSN">1531-8257</identifier>
<identifier type="DOI">10.1002/(ISSN)1531-8257</identifier>
<identifier type="PublisherID">MDS</identifier>
<part>
<date>2010</date>
<detail type="volume">
<caption>vol.</caption>
<number>25</number>
</detail>
<detail type="issue">
<caption>no.</caption>
<number>15</number>
</detail>
<extent unit="pages">
<start>2674</start>
<end>2678</end>
<total>5</total>
</extent>
</part>
</relatedItem>
<identifier type="istex">E9F8FF8F2AD3605A6897C1A8AD7BB47D8980E2CF</identifier>
<identifier type="DOI">10.1002/mds.23284</identifier>
<identifier type="ArticleID">MDS23284</identifier>
<accessCondition type="use and reproduction" contentType="copyright">Copyright © 2010 Movement Disorder Society</accessCondition>
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<recordContentSource>WILEY</recordContentSource>
<recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin>
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