Cortical and subcortical diseases: Do true neuropsychological differences exist?
Identifieur interne : 001888 ( Main/Corpus ); précédent : 001887; suivant : 001889Cortical and subcortical diseases: Do true neuropsychological differences exist?
Auteurs : Juan Carlos Arango-Lasprilla ; Heather Rogers ; Jean Lengenfelder ; John Deluca ; Sonia Moreno ; Francisco LoperaSource :
- Archives of Clinical Neuropsychology [ 0887-6177 ] ; 2006-01.
Abstract
Previous work examining the cortical-subcortical distinction as it relates to cognitive patterns has not typically used genetic confirmation to identify these groups, controlled for age, or used a comprehensive battery to assess specific cognitive abilities. The present study is the first to include only genetically confirmed Familial Alzheimer's disease (FAD) and Huntington's disease (HD) patients to evaluate this distinction. Ten patients with FAD, 11 patients with HD, and 17 matched healthy individuals were compared on a comprehensive neuropsychological battery that included tasks of language, memory, attention, visual-spatial, and executive function. The only neuropsychological measures to differentiate the two clinical groups were Animal Fluency and Letter Fluency; performance on all other measures did not differ. Although the neuropsychological battery adequately distinguished between clinical and healthy individuals, it was not useful to further differentiate the cortical or subcortical nature of the disease. FAD and HD appear to have similar neuropsychological profiles; therefore the cortical versus subcortical cognitive distinction may not be clinically meaningful.
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DOI: 10.1016/j.acn.2005.07.004
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first="John" last="Deluca">John Deluca</name><affiliation><mods:affiliation>nd Neuroscience Laboratory, Kessler Medical Rehabilitation Research and Education Corporation 300 Execute Drive, Suite 010 West Orange, NJ 07052, USA</mods:affiliation></affiliation><affiliation><mods:affiliation>ilitation, University of Medicine and Dentistry of New Jersey Newark, NJ, USA</mods:affiliation></affiliation></author><author><name sortKey="Moreno, Sonia" sort="Moreno, Sonia" uniqKey="Moreno S" first="Sonia" last="Moreno">Sonia Moreno</name><affiliation><mods:affiliation>ience Group, University of Antioquia Medellín, Colombia</mods:affiliation></affiliation></author><author><name sortKey="Lopera, Francisco" sort="Lopera, Francisco" uniqKey="Lopera F" first="Francisco" last="Lopera">Francisco Lopera</name><affiliation><mods:affiliation>ience Group, University of Antioquia Medellín, Colombia</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Archives of Clinical Neuropsychology</title><idno type="ISSN">0887-6177</idno><idno type="eISSN">1873-5843</idno><imprint><publisher>Elsevier</publisher><date type="published" when="2006-01">2006-01</date><biblScope unit="volume">21</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="29">29</biblScope><biblScope unit="page" to="40">40</biblScope></imprint><idno type="ISSN">0887-6177</idno></series><idno type="istex">3342B44DA712413EF973E14A38EC9B8CA786F095</idno><idno type="DOI">10.1016/j.acn.2005.07.004</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0887-6177</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">Previous work examining the cortical-subcortical distinction as it relates to cognitive patterns has not typically used genetic confirmation to identify these groups, controlled for age, or used a comprehensive battery to assess specific cognitive abilities. The present study is the first to include only genetically confirmed Familial Alzheimer's disease (FAD) and Huntington's disease (HD) patients to evaluate this distinction. Ten patients with FAD, 11 patients with HD, and 17 matched healthy individuals were compared on a comprehensive neuropsychological battery that included tasks of language, memory, attention, visual-spatial, and executive function. The only neuropsychological measures to differentiate the two clinical groups were Animal Fluency and Letter Fluency; performance on all other measures did not differ. Although the neuropsychological battery adequately distinguished between clinical and healthy individuals, it was not useful to further differentiate the cortical or subcortical nature of the disease. FAD and HD appear to have similar neuropsychological profiles; therefore the cortical versus subcortical cognitive distinction may not be clinically meaningful.</div></front></TEI><istex><corpusName>oup</corpusName><author><json:item><name>Juan Carlos Arango-Lasprilla</name><affiliations><json:string>Neuropsychology and Neuroscience Laboratory, Kessler Medical Rehabilitation Research and Education Corporation 300 Execute Drive, Suite 010 West Orange, NJ 07052, USA</json:string><json:string>Department of Physical Medicine and Rehabilitation, University of Medicine and Dentistry of New Jersey Newark, NJ, USA</json:string><json:string>Neuroscience Group, University of Antioquia Medellín, Colombia</json:string><json:string>E-mail: jcarango@kmrrec.org</json:string></affiliations></json:item><json:item><name>Heather Rogers</name><affiliations><json:string>Uniformed Services University of the Health Sciences Bethesda, MD, USA</json:string></affiliations></json:item><json:item><name>Jean Lengenfelder</name><affiliations><json:string>Neuropsychology and Neuroscience Laboratory, Kessler Medical Rehabilitation Research and Education Corporation 300 Execute Drive, Suite 010 West Orange, NJ 07052, USA</json:string><json:string>Department of Physical Medicine and Rehabilitation, University of Medicine and Dentistry of New Jersey Newark, NJ, USA</json:string></affiliations></json:item><json:item><name>John DeLuca</name><affiliations><json:string>Neuropsychology and Neuroscience Laboratory, Kessler Medical Rehabilitation Research and Education Corporation 300 Execute Drive, Suite 010 West Orange, NJ 07052, USA</json:string><json:string>Department of Physical Medicine and Rehabilitation, University of Medicine and Dentistry of New Jersey Newark, NJ, USA</json:string></affiliations></json:item><json:item><name>Sonia Moreno</name><affiliations><json:string>Neuroscience Group, University of Antioquia Medellín, Colombia</json:string></affiliations></json:item><json:item><name>Francisco Lopera</name><affiliations><json:string>Neuroscience Group, University of Antioquia Medellín, Colombia</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Articles</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Alzheimer's disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Huntington's disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Cortical dementia</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Subcortical disease</value></json:item></subject><language><json:string>eng</json:string></language><abstract>Previous work examining the cortical-subcortical distinction as it relates to cognitive patterns has not typically used genetic confirmation to identify these groups, controlled for age, or used a comprehensive battery to assess specific cognitive abilities. The present study is the first to include only genetically confirmed Familial Alzheimer's disease (FAD) and Huntington's disease (HD) patients to evaluate this distinction. Ten patients with FAD, 11 patients with HD, and 17 matched healthy individuals were compared on a comprehensive neuropsychological battery that included tasks of language, memory, attention, visual-spatial, and executive function. The only neuropsychological measures to differentiate the two clinical groups were Animal Fluency and Letter Fluency; performance on all other measures did not differ. Although the neuropsychological battery adequately distinguished between clinical and healthy individuals, it was not useful to further differentiate the cortical or subcortical nature of the disease. FAD and HD appear to have similar neuropsychological profiles; therefore the cortical versus subcortical cognitive distinction may not be clinically meaningful.</abstract><qualityIndicators><score>6.932</score><pdfVersion>1.3</pdfVersion><pdfPageSize>544 x 742 pts</pdfPageSize><refBibsNative>false</refBibsNative><keywordCount>5</keywordCount><abstractCharCount>1192</abstractCharCount><pdfWordCount>7242</pdfWordCount><pdfCharCount>45895</pdfCharCount><pdfPageCount>12</pdfPageCount><abstractWordCount>161</abstractWordCount></qualityIndicators><title>Cortical and subcortical diseases: Do true neuropsychological differences exist?</title><genre><json:string>research-article</json:string></genre><host><volume>21</volume><pages><last>40</last><first>29</first></pages><issn><json:string>0887-6177</json:string></issn><issue>1</issue><genre></genre><language><json:string>unknown</json:string></language><eissn><json:string>1873-5843</json:string></eissn><title>Archives of Clinical 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Research and Education Corporation 300 Execute Drive, Suite 010 West Orange, NJ 07052, USA</affiliation><affiliation>ilitation, University of Medicine and Dentistry of New Jersey Newark, NJ, USA</affiliation></author><author><persName><forename type="first">Sonia</forename><surname>Moreno</surname></persName><affiliation>ience Group, University of Antioquia Medellín, Colombia</affiliation></author><author><persName><forename type="first">Francisco</forename><surname>Lopera</surname></persName><affiliation>ience Group, University of Antioquia Medellín, Colombia</affiliation></author></analytic><monogr><title level="j">Archives of Clinical Neuropsychology</title><idno type="pISSN">0887-6177</idno><idno type="eISSN">1873-5843</idno><imprint><publisher>Elsevier</publisher><date type="published" when="2006-01"></date><biblScope unit="volume">21</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="29">29</biblScope><biblScope unit="page" 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The present study is the first to include only genetically confirmed Familial Alzheimer's disease (FAD) and Huntington's disease (HD) patients to evaluate this distinction. Ten patients with FAD, 11 patients with HD, and 17 matched healthy individuals were compared on a comprehensive neuropsychological battery that included tasks of language, memory, attention, visual-spatial, and executive function. The only neuropsychological measures to differentiate the two clinical groups were Animal Fluency and Letter Fluency; performance on all other measures did not differ. Although the neuropsychological battery adequately distinguished between clinical and healthy individuals, it was not useful to further differentiate the cortical or subcortical nature of the disease. FAD and HD appear to have similar neuropsychological profiles; therefore the cortical versus subcortical cognitive distinction may not be clinically meaningful.</p></abstract><textClass><keywords scheme="keyword"><list><item><term>Articles</term></item></list></keywords></textClass><textClass><keywords scheme="keyword"><list><head>Keywords</head><item><term>Alzheimer's disease</term></item><item><term>Huntington's disease</term></item><item><term>Cortical dementia</term></item><item><term>Subcortical disease</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2006-01">Published</change><change xml:id="refBibs-istex" who="#ISTEX-API" when="2016-3-14">References added</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/3342B44DA712413EF973E14A38EC9B8CA786F095/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="corpus oup" wicri:toSee="no header"><istex:docType PUBLIC="-//NLM//DTD Journal Publishing DTD v2.3 20070202//EN" URI="journalpublishing.dtd" name="istex:docType"></istex:docType><istex:document><article article-type="research-article"><front><journal-meta><journal-id journal-id-type="hwp">acn</journal-id><journal-id journal-id-type="publisher-id">acn</journal-id><journal-title>Archives of Clinical Neuropsychology</journal-title><issn pub-type="ppub">0887-6177</issn><issn pub-type="epub">1873-5843</issn><publisher><publisher-name>Elsevier</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.1016/j.acn.2005.07.004</article-id><article-categories><subj-group><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Cortical and subcortical diseases: Do true neuropsychological differences exist? <xref ref-type="fn" rid="fn1">☆</xref></article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Arango-Lasprilla</surname><given-names>Juan Carlos</given-names></name><xref ref-type="aff" rid="au1"><sup>a</sup></xref><xref ref-type="aff" rid="au2"><sup>b</sup></xref><xref ref-type="aff" rid="au3"><sup>c</sup></xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Rogers</surname><given-names>Heather</given-names></name><xref ref-type="aff" rid="au4"><sup>d</sup></xref></contrib><contrib contrib-type="author"><name><surname>Lengenfelder</surname><given-names>Jean</given-names></name><xref ref-type="aff" rid="au1"><sup>a</sup></xref><xref ref-type="aff" rid="au2"><sup>b</sup></xref></contrib><contrib contrib-type="author"><name><surname>DeLuca</surname><given-names>John</given-names></name><xref ref-type="aff" rid="au1"><sup>a</sup></xref><xref ref-type="aff" rid="au2"><sup>b</sup></xref></contrib><contrib contrib-type="author"><name><surname>Moreno</surname><given-names>Sonia</given-names></name><xref ref-type="aff" rid="au3"><sup>c</sup></xref></contrib><contrib contrib-type="author"><name><surname>Lopera</surname><given-names>Francisco</given-names></name><xref ref-type="aff" rid="au3"><sup>c</sup></xref></contrib><aff id="au1"><label><sup>a</sup></label><institution>Neuropsychology and Neuroscience Laboratory, Kessler Medical Rehabilitation Research and Education Corporation</institution> <addr-line>300 Execute Drive, Suite 010 West Orange, NJ 07052, USA</addr-line></aff><aff id="au2"><label><sup>b</sup></label><institution>Department of Physical Medicine and Rehabilitation, University of Medicine and Dentistry of New Jersey</institution> <addr-line>Newark, NJ, USA</addr-line></aff><aff id="au3"><label><sup>c</sup></label><institution>Neuroscience Group, University of Antioquia</institution> <addr-line>Medellín, Colombia</addr-line></aff><aff id="au4"><label><sup>d</sup></label><institution>Uniformed Services University of the Health Sciences</institution> <addr-line>Bethesda, MD, USA</addr-line></aff></contrib-group><author-notes><fn id="fn1"><label>☆</label><p>The opinions and assertions contained herein are the private views of the authors and are not to be construed as being official or as reflecting the views of the Uniformed Services University of the Health Sciences or the Department of Defense.</p></fn><corresp id="cor1"><label>*</label>Corresponding author. Tel.: <phone>+1 973 530 3650</phone>; fax: <fax>+1 973 736 7880</fax>. E-mail address: <email>jcarango@kmrrec.org</email></corresp></author-notes><pub-date pub-type="ppub"><month>1</month><year>2006</year></pub-date><volume>21</volume><issue>1</issue><fpage>29</fpage><lpage>40</lpage><history><date date-type="accepted"><day>18</day><month>7</month><year>2005</year></date></history><copyright-statement>© 2005 National Academy of Neuropsychology</copyright-statement><copyright-year>2005</copyright-year><abstract><title>Abstract</title><p>Previous work examining the cortical-subcortical distinction as it relates to cognitive patterns has not typically used genetic confirmation to identify these groups, controlled for age, or used a comprehensive battery to assess specific cognitive abilities. The present study is the first to include only genetically confirmed Familial Alzheimer's disease (FAD) and Huntington's disease (HD) patients to evaluate this distinction. Ten patients with FAD, 11 patients with HD, and 17 matched healthy individuals were compared on a comprehensive neuropsychological battery that included tasks of language, memory, attention, visual-spatial, and executive function. The only neuropsychological measures to differentiate the two clinical groups were Animal Fluency and Letter Fluency; performance on all other measures did not differ. Although the neuropsychological battery adequately distinguished between clinical and healthy individuals, it was not useful to further differentiate the cortical or subcortical nature of the disease. FAD and HD appear to have similar neuropsychological profiles; therefore the cortical versus subcortical cognitive distinction may not be clinically meaningful.</p></abstract><kwd-group><kwd>Alzheimer's disease</kwd><kwd>Huntington's disease</kwd><kwd>Cortical dementia</kwd><kwd>Subcortical disease</kwd></kwd-group></article-meta></front></article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo><title>Cortical and subcortical diseases: Do true neuropsychological differences exist?</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Cortical and subcortical diseases: Do true neuropsychological differences exist? ☆</title></titleInfo><name type="personal"><namePart type="given">Juan Carlos</namePart><namePart type="family">Arango-Lasprilla</namePart><affiliation>nd Neuroscience Laboratory, Kessler Medical Rehabilitation Research and Education Corporation 300 Execute Drive, Suite 010 West Orange, NJ 07052, USA</affiliation><affiliation>ilitation, University of Medicine and Dentistry of New Jersey Newark, NJ, USA</affiliation><affiliation>ience Group, University of Antioquia Medellín, Colombia</affiliation><affiliation>E-mail: jcarango@kmrrec.org</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Heather</namePart><namePart type="family">Rogers</namePart><affiliation>Services University of the Health Sciences Bethesda, MD, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jean</namePart><namePart type="family">Lengenfelder</namePart><affiliation>nd Neuroscience Laboratory, Kessler Medical Rehabilitation Research and Education Corporation 300 Execute Drive, Suite 010 West Orange, NJ 07052, USA</affiliation><affiliation>ilitation, University of Medicine and Dentistry of New Jersey Newark, NJ, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">John</namePart><namePart type="family">DeLuca</namePart><affiliation>nd Neuroscience Laboratory, Kessler Medical Rehabilitation Research and Education Corporation 300 Execute Drive, Suite 010 West Orange, NJ 07052, USA</affiliation><affiliation>ilitation, University of Medicine and Dentistry of New Jersey Newark, NJ, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Sonia</namePart><namePart type="family">Moreno</namePart><affiliation>ience Group, University of Antioquia Medellín, Colombia</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Francisco</namePart><namePart type="family">Lopera</namePart><affiliation>ience Group, University of Antioquia Medellín, Colombia</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="research-article"></genre><subject><topic>Articles</topic></subject><originInfo><publisher>Elsevier</publisher><dateIssued encoding="w3cdtf">2006-01</dateIssued><copyrightDate encoding="w3cdtf">2005</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract>Previous work examining the cortical-subcortical distinction as it relates to cognitive patterns has not typically used genetic confirmation to identify these groups, controlled for age, or used a comprehensive battery to assess specific cognitive abilities. The present study is the first to include only genetically confirmed Familial Alzheimer's disease (FAD) and Huntington's disease (HD) patients to evaluate this distinction. Ten patients with FAD, 11 patients with HD, and 17 matched healthy individuals were compared on a comprehensive neuropsychological battery that included tasks of language, memory, attention, visual-spatial, and executive function. The only neuropsychological measures to differentiate the two clinical groups were Animal Fluency and Letter Fluency; performance on all other measures did not differ. Although the neuropsychological battery adequately distinguished between clinical and healthy individuals, it was not useful to further differentiate the cortical or subcortical nature of the disease. FAD and HD appear to have similar neuropsychological profiles; therefore the cortical versus subcortical cognitive distinction may not be clinically meaningful.</abstract><note type="footnotes">The opinions and assertions contained herein are the private views of the authors and are not to be construed as being official or as reflecting the views of the Uniformed Services University of the Health Sciences or the Department of Defense.</note><subject><genre>Keywords</genre><topic>Alzheimer's disease</topic><topic>Huntington's disease</topic><topic>Cortical dementia</topic><topic>Subcortical disease</topic></subject><relatedItem type="host"><titleInfo><title>Archives of Clinical Neuropsychology</title></titleInfo><genre type="Journal">journal</genre><identifier type="ISSN">0887-6177</identifier><identifier type="eISSN">1873-5843</identifier><identifier type="PublisherID">acn</identifier><identifier type="PublisherID-hwp">acn</identifier><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>21</number></detail><detail type="issue"><caption>no.</caption><number>1</number></detail><extent unit="pages"><start>29</start><end>40</end></extent></part></relatedItem><identifier type="istex">3342B44DA712413EF973E14A38EC9B8CA786F095</identifier><identifier type="DOI">10.1016/j.acn.2005.07.004</identifier><accessCondition type="use and reproduction" contentType="copyright">© 2005 National Academy of Neuropsychology</accessCondition><recordInfo><recordContentSource>OUP</recordContentSource></recordInfo></mods></metadata><enrichments><istex:catWosTEI uri="https://api.istex.fr/document/3342B44DA712413EF973E14A38EC9B8CA786F095/enrichments/catWos"><teiHeader><profileDesc><textClass><classCode scheme="WOS">PSYCHOLOGY, CLINICAL</classCode><classCode scheme="WOS">PSYCHOLOGY</classCode></textClass></profileDesc></teiHeader></istex:catWosTEI></enrichments><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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