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Survey of U.S. Neurologists' Attitudes Towards Deep Brain Stimulation for Parkinson's Disease

Identifieur interne : 001724 ( Main/Corpus ); précédent : 001723; suivant : 001725

Survey of U.S. Neurologists' Attitudes Towards Deep Brain Stimulation for Parkinson's Disease

Auteurs : Ludy C. Shih ; Daniel Tarsy

Source :

RBID : ISTEX:1D9EE26C5DEE702DF5350DF8351846544D65813F

English descriptors

Abstract

Objectives:  Deep brain stimulation (DBS) for Parkinson's disease (PD) was approved by the Food and Drug Administration in 2002 and has demonstrated clinical benefit in advanced PD. Our aim was to assess attitudes of U.S. neurologists towards the role of DBS in management of advanced PD. Materials and Methods:  We sent a 40‐item Internet‐based survey assessing opinions regarding the role of medical and surgical therapies in managing PD to 7722 neurologists in the American Medical Association Physician MasterFile data base. Results:  The response rate was low (4.2%). In total, 78 of the 298 (26%) responders self‐identified as movement disorders specialists. Specialists and non‐specialists had differences on a number of medical strategies used to manage PD. There were no statistically significant differences in reasons for or against referring patients for DBS, except for the number of non‐specialists who agreed with referring a patient who had a “poor or absent response to levodopa” (71% vs. 16%, p < 0.001). Both groups indicated a need for more information concerning appropriate indications for DBS, adverse effects of surgery, and postoperative programming. Conclusions:  Movement disorders specialists and non‐specialists were in general agreement towards the beneficial role of DBS in management of advanced PD except for whether to refer patients with poor or absent response to levodopa.

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DOI: 10.1111/j.1525-1403.2011.00350.x

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ISTEX:1D9EE26C5DEE702DF5350DF8351846544D65813F

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<b>Objectives: </b>
Deep brain stimulation (DBS) for Parkinson's disease (PD) was approved by the Food and Drug Administration in 2002 and has demonstrated clinical benefit in advanced PD. Our aim was to assess attitudes of U.S. neurologists towards the role of DBS in management of advanced PD.</p>
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We sent a 40‐item Internet‐based survey assessing opinions regarding the role of medical and surgical therapies in managing PD to 7722 neurologists in the American Medical Association Physician MasterFile data base.</p>
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<b>Results: </b>
The response rate was low (4.2%). In total, 78 of the 298 (26%) responders self‐identified as movement disorders specialists. Specialists and non‐specialists had differences on a number of medical strategies used to manage PD. There were no statistically significant differences in reasons for or against referring patients for DBS, except for the number of non‐specialists who agreed with referring a patient who had a “poor or absent response to levodopa” (71% vs. 16%,
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<b>Conflict of Interest:</b>
Ludy Shih received support from the Clinical Investigator Training Program: Beth Israel Deaconess Medical Center—Harvard/MIT Health Sciences and Technology, in collaboration with Pfizer Inc. and Merck & Co. Daniel Tarsy has received research funding from Schwarz Pharma and patient education grants from Teva Neurosciences and Boehringer Ingelheim. He has also received consulting fees from Eisai Neuroscience. Medtronic funded the costs associated with administering the survey and data collection. The authors did not receive any payments for conducting the study. Data collection and results interpretation were solely performed by the authors.</p>
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<abstract lang="en">Objectives:  Deep brain stimulation (DBS) for Parkinson's disease (PD) was approved by the Food and Drug Administration in 2002 and has demonstrated clinical benefit in advanced PD. Our aim was to assess attitudes of U.S. neurologists towards the role of DBS in management of advanced PD. Materials and Methods:  We sent a 40‐item Internet‐based survey assessing opinions regarding the role of medical and surgical therapies in managing PD to 7722 neurologists in the American Medical Association Physician MasterFile data base. Results:  The response rate was low (4.2%). In total, 78 of the 298 (26%) responders self‐identified as movement disorders specialists. Specialists and non‐specialists had differences on a number of medical strategies used to manage PD. There were no statistically significant differences in reasons for or against referring patients for DBS, except for the number of non‐specialists who agreed with referring a patient who had a “poor or absent response to levodopa” (71% vs. 16%, p < 0.001). Both groups indicated a need for more information concerning appropriate indications for DBS, adverse effects of surgery, and postoperative programming. Conclusions:  Movement disorders specialists and non‐specialists were in general agreement towards the beneficial role of DBS in management of advanced PD except for whether to refer patients with poor or absent response to levodopa.</abstract>
<subject lang="en">
<genre>Keywords</genre>
<topic>Deep brain stimulation</topic>
<topic>Parkinson's disease</topic>
<topic>patient selection</topic>
<topic>prospective nonrandomized study</topic>
<topic>subthalamic nucleus</topic>
</subject>
<relatedItem type="host">
<titleInfo>
<title>Neuromodulation: Technology at the Neural Interface</title>
</titleInfo>
<genre type="Journal">journal</genre>
<identifier type="ISSN">1094-7159</identifier>
<identifier type="eISSN">1525-1403</identifier>
<identifier type="DOI">10.1111/(ISSN)1525-1403</identifier>
<identifier type="PublisherID">NER</identifier>
<part>
<date>2011</date>
<detail type="volume">
<caption>vol.</caption>
<number>14</number>
</detail>
<detail type="issue">
<caption>no.</caption>
<number>3</number>
</detail>
<extent unit="pages">
<start>208</start>
<end>213</end>
<total>6</total>
</extent>
</part>
</relatedItem>
<identifier type="istex">1D9EE26C5DEE702DF5350DF8351846544D65813F</identifier>
<identifier type="DOI">10.1111/j.1525-1403.2011.00350.x</identifier>
<identifier type="ArticleID">NER350</identifier>
<accessCondition type="use and reproduction" contentType="copyright">© 2011 International Neuromodulation Society</accessCondition>
<recordInfo>
<recordContentSource>WILEY</recordContentSource>
<recordOrigin>Blackwell Publishing Inc</recordOrigin>
</recordInfo>
</mods>
</metadata>
<serie></serie>
</istex>
</record>

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