Accuracy of algorithms to predict accessory pathway location in children with Wolff–Parkinson–White syndrome
Identifieur interne : 001650 ( Main/Corpus ); précédent : 001649; suivant : 001651Accuracy of algorithms to predict accessory pathway location in children with Wolff–Parkinson–White syndrome
Auteurs : Christopher Wren ; Melanie Vogel ; Stephen Lord ; Dominic Abrams ; John Bourke ; Philip Rees ; Eric RosenthalSource :
- Heart [ 1355-6037 ] ; 2012-02-01.
Abstract
Objective The aim of this study was to examine the accuracy in predicting pathway location in children with Wolff–Parkinson–White syndrome for each of seven published algorithms. Patients and interventions ECGs from 100 consecutive children with Wolff–Parkinson–White syndrome undergoing electrophysiological study were analysed by six investigators using seven published algorithms, six of which had been developed in adult patients. Main outcome measures Accuracy and concordance of predictions were adjusted for the number of pathway locations. Results Accessory pathways were left-sided in 49, septal in 20 and right-sided in 31 children. Overall accuracy of prediction was 30–49% for the exact location and 61–68% including adjacent locations. Concordance between investigators varied between 41% and 86%. No algorithm was better at predicting septal pathways (accuracy 5–35%, improving to 40–78% including adjacent locations), but one was significantly worse. Predictive accuracy was 24–53% for the exact location of right-sided pathways (50–71% including adjacent locations) and 32–55% for the exact location of left-sided pathways (58–73% including adjacent locations). Conclusions All algorithms were less accurate in our hands than in other authors' own assessment. None performed well in identifying midseptal or right anteroseptal accessory pathway locations.
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DOI: 10.1136/heartjnl-2011-300269
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<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Accuracy of algorithms to predict accessory pathway location in children with Wolff–Parkinson–White syndrome</title><author><name sortKey="Wren, Christopher" sort="Wren, Christopher" uniqKey="Wren C" first="Christopher" last="Wren">Christopher Wren</name><affiliation><mods:affiliation>Freeman Hospital, Newcastle upon Tyne, UK</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: christopher.wren@nuth.nhs.uk</mods:affiliation></affiliation></author><author><name sortKey="Vogel, Melanie" sort="Vogel, Melanie" uniqKey="Vogel M" first="Melanie" last="Vogel">Melanie Vogel</name><affiliation><mods:affiliation>Justus Liebig University, Giessen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Lord, Stephen" sort="Lord, Stephen" uniqKey="Lord S" first="Stephen" last="Lord">Stephen Lord</name><affiliation><mods:affiliation>Freeman Hospital, Newcastle upon Tyne, UK</mods:affiliation></affiliation></author><author><name sortKey="Abrams, Dominic" sort="Abrams, Dominic" uniqKey="Abrams D" first="Dominic" last="Abrams">Dominic Abrams</name><affiliation><mods:affiliation>Great Ormond Street Hospital, London, UK</mods:affiliation></affiliation><affiliation><mods:affiliation>St. Bartholomew's Hospital, London, UK</mods:affiliation></affiliation></author><author><name sortKey="Bourke, John" sort="Bourke, John" uniqKey="Bourke J" first="John" last="Bourke">John Bourke</name><affiliation><mods:affiliation>Freeman Hospital, Newcastle upon Tyne, UK</mods:affiliation></affiliation></author><author><name sortKey="Rees, Philip" sort="Rees, Philip" uniqKey="Rees P" first="Philip" last="Rees">Philip Rees</name><affiliation><mods:affiliation>Great Ormond Street Hospital, London, UK</mods:affiliation></affiliation></author><author><name sortKey="Rosenthal, Eric" sort="Rosenthal, Eric" uniqKey="Rosenthal E" first="Eric" last="Rosenthal">Eric Rosenthal</name><affiliation><mods:affiliation>Evelina Children's Hospital, London, UK</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:3821817595BC87C721CAE24E19BDA7CAAC0A7B53</idno><date when="2011" year="2011">2011</date><idno type="doi">10.1136/heartjnl-2011-300269</idno><idno type="url">https://api.istex.fr/document/3821817595BC87C721CAE24E19BDA7CAAC0A7B53/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">001650</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">Accuracy of algorithms to predict accessory pathway location in children with Wolff–Parkinson–White syndrome</title><author><name sortKey="Wren, Christopher" sort="Wren, Christopher" uniqKey="Wren C" first="Christopher" last="Wren">Christopher Wren</name><affiliation><mods:affiliation>Freeman Hospital, Newcastle upon Tyne, UK</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: christopher.wren@nuth.nhs.uk</mods:affiliation></affiliation></author><author><name sortKey="Vogel, Melanie" sort="Vogel, Melanie" uniqKey="Vogel M" first="Melanie" last="Vogel">Melanie Vogel</name><affiliation><mods:affiliation>Justus Liebig University, Giessen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Lord, Stephen" sort="Lord, Stephen" uniqKey="Lord S" first="Stephen" last="Lord">Stephen Lord</name><affiliation><mods:affiliation>Freeman Hospital, Newcastle upon Tyne, UK</mods:affiliation></affiliation></author><author><name sortKey="Abrams, Dominic" sort="Abrams, Dominic" uniqKey="Abrams D" first="Dominic" last="Abrams">Dominic Abrams</name><affiliation><mods:affiliation>Great Ormond Street Hospital, London, UK</mods:affiliation></affiliation><affiliation><mods:affiliation>St. Bartholomew's Hospital, London, UK</mods:affiliation></affiliation></author><author><name sortKey="Bourke, John" sort="Bourke, John" uniqKey="Bourke J" first="John" last="Bourke">John Bourke</name><affiliation><mods:affiliation>Freeman Hospital, Newcastle upon Tyne, UK</mods:affiliation></affiliation></author><author><name sortKey="Rees, Philip" sort="Rees, Philip" uniqKey="Rees P" first="Philip" last="Rees">Philip Rees</name><affiliation><mods:affiliation>Great Ormond Street Hospital, London, UK</mods:affiliation></affiliation></author><author><name sortKey="Rosenthal, Eric" sort="Rosenthal, Eric" uniqKey="Rosenthal E" first="Eric" last="Rosenthal">Eric Rosenthal</name><affiliation><mods:affiliation>Evelina Children's Hospital, London, UK</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Heart</title><title level="j" type="abbrev">Heart</title><idno type="ISSN">1355-6037</idno><idno type="eISSN">1468-201X</idno><imprint><publisher>BMJ Publishing Group Ltd and British Cardiovascular Society</publisher><date type="published" when="2012-02-01">2012-02-01</date><biblScope unit="volume">98</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="202">202</biblScope></imprint><idno type="ISSN">1355-6037</idno></series><idno type="istex">3821817595BC87C721CAE24E19BDA7CAAC0A7B53</idno><idno type="DOI">10.1136/heartjnl-2011-300269</idno><idno type="href">heartjnl-98-202.pdf</idno><idno type="ArticleID">heartjnl-2011-300269</idno><idno type="PMID">21917661</idno><idno type="local">heartjnl;98/3/202</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1355-6037</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">Objective The aim of this study was to examine the accuracy in predicting pathway location in children with Wolff–Parkinson–White syndrome for each of seven published algorithms. Patients and interventions ECGs from 100 consecutive children with Wolff–Parkinson–White syndrome undergoing electrophysiological study were analysed by six investigators using seven published algorithms, six of which had been developed in adult patients. Main outcome measures Accuracy and concordance of predictions were adjusted for the number of pathway locations. Results Accessory pathways were left-sided in 49, septal in 20 and right-sided in 31 children. Overall accuracy of prediction was 30–49% for the exact location and 61–68% including adjacent locations. Concordance between investigators varied between 41% and 86%. No algorithm was better at predicting septal pathways (accuracy 5–35%, improving to 40–78% including adjacent locations), but one was significantly worse. Predictive accuracy was 24–53% for the exact location of right-sided pathways (50–71% including adjacent locations) and 32–55% for the exact location of left-sided pathways (58–73% including adjacent locations). Conclusions All algorithms were less accurate in our hands than in other authors' own assessment. None performed well in identifying midseptal or right anteroseptal accessory pathway locations.</div></front></TEI><istex><corpusName>bmj</corpusName><author><json:item><name>Christopher Wren</name><affiliations><json:string>Freeman Hospital, Newcastle upon Tyne, UK</json:string><json:string>E-mail: christopher.wren@nuth.nhs.uk</json:string></affiliations></json:item><json:item><name>Melanie Vogel</name><affiliations><json:string>Justus Liebig University, Giessen, Germany</json:string></affiliations></json:item><json:item><name>Stephen Lord</name><affiliations><json:string>Freeman Hospital, Newcastle upon Tyne, UK</json:string></affiliations></json:item><json:item><name>Dominic Abrams</name><affiliations><json:string>Great Ormond Street Hospital, London, UK</json:string><json:string>St. Bartholomew's Hospital, London, UK</json:string></affiliations></json:item><json:item><name>John Bourke</name><affiliations><json:string>Freeman Hospital, Newcastle upon Tyne, UK</json:string></affiliations></json:item><json:item><name>Philip Rees</name><affiliations><json:string>Great Ormond Street Hospital, London, UK</json:string></affiliations></json:item><json:item><name>Eric Rosenthal</name><affiliations><json:string>Evelina Children's Hospital, London, UK</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Heart rhythm disorders</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Wolff–Parkinson–White syndrome</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>paediatrics</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>electrophysiology</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>electrocardiography</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>paediatric electrophysiology</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>paediatric arrythmias</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>congenital heart disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>paediatric cardiology</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>embryology</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>autonomic defibrillator</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>spectral analysis</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>sinus node function</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>autonomic nervous system</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>transplantation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>congenital—paediatric</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>congenital—adult</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>radiofrequency catheter ablation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>pacing</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>arrhythmias</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>cardiac arrhythmias</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>muscular dystrophy and cardiac involvement</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>catheter ablation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>cardiac electrophysiology</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>mitochondrial cardiomyopathy</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>sudden cardiac death</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>cardiomyopathy</value></json:item></subject><language><json:string>eng</json:string></language><abstract>Objective The aim of this study was to examine the accuracy in predicting pathway location in children with Wolff–Parkinson–White syndrome for each of seven published algorithms. Patients and interventions ECGs from 100 consecutive children with Wolff–Parkinson–White syndrome undergoing electrophysiological study were analysed by six investigators using seven published algorithms, six of which had been developed in adult patients. Main outcome measures Accuracy and concordance of predictions were adjusted for the number of pathway locations. Results Accessory pathways were left-sided in 49, septal in 20 and right-sided in 31 children. Overall accuracy of prediction was 30–49% for the exact location and 61–68% including adjacent locations. Concordance between investigators varied between 41% and 86%. No algorithm was better at predicting septal pathways (accuracy 5–35%, improving to 40–78% including adjacent locations), but one was significantly worse. Predictive accuracy was 24–53% for the exact location of right-sided pathways (50–71% including adjacent locations) and 32–55% for the exact location of left-sided pathways (58–73% including adjacent locations). Conclusions All algorithms were less accurate in our hands than in other authors' own assessment. None performed well in identifying midseptal or right anteroseptal accessory pathway locations.</abstract><qualityIndicators><score>6.257</score><pdfVersion>1.4</pdfVersion><pdfPageSize>595.276 x 793.701 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>27</keywordCount><abstractCharCount>1371</abstractCharCount><pdfWordCount>3501</pdfWordCount><pdfCharCount>23354</pdfCharCount><pdfPageCount>5</pdfPageCount><abstractWordCount>188</abstractWordCount></qualityIndicators><title>Accuracy of algorithms to predict accessory pathway location in children with Wolff–Parkinson–White syndrome</title><pmid><json:string>21917661</json:string></pmid><genre><json:string>research-article</json:string></genre><host><volume>98</volume><pages><first>202</first></pages><issn><json:string>1355-6037</json:string></issn><issue>3</issue><genre></genre><language><json:string>unknown</json:string></language><eissn><json:string>1468-201X</json:string></eissn><title>Heart</title></host><publicationDate>2012</publicationDate><copyrightDate>2011</copyrightDate><doi><json:string>10.1136/heartjnl-2011-300269</json:string></doi><id>3821817595BC87C721CAE24E19BDA7CAAC0A7B53</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/3821817595BC87C721CAE24E19BDA7CAAC0A7B53/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/3821817595BC87C721CAE24E19BDA7CAAC0A7B53/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/3821817595BC87C721CAE24E19BDA7CAAC0A7B53/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a">Accuracy of algorithms to predict accessory pathway location in children with Wolff–Parkinson–White syndrome</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>BMJ Publishing Group Ltd and British Cardiovascular Society</publisher><availability><p>BMJ</p></availability><date>2011-09-13</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a">Accuracy of algorithms to predict accessory pathway location in children with Wolff–Parkinson–White syndrome</title><author corresp="yes"><persName><forename type="first">Christopher</forename><surname>Wren</surname></persName><email>christopher.wren@nuth.nhs.uk</email><affiliation>Freeman Hospital, Newcastle upon Tyne, UK</affiliation></author><author><persName><forename type="first">Melanie</forename><surname>Vogel</surname></persName><affiliation>Justus Liebig University, Giessen, Germany</affiliation></author><author><persName><forename type="first">Stephen</forename><surname>Lord</surname></persName><affiliation>Freeman Hospital, Newcastle upon Tyne, UK</affiliation></author><author><persName><forename type="first">Dominic</forename><surname>Abrams</surname></persName><affiliation>Great Ormond Street Hospital, London, UK</affiliation><affiliation>St. Bartholomew's Hospital, London, UK</affiliation></author><author><persName><forename type="first">John</forename><surname>Bourke</surname></persName><affiliation>Freeman Hospital, Newcastle upon Tyne, UK</affiliation></author><author><persName><forename type="first">Philip</forename><surname>Rees</surname></persName><affiliation>Great Ormond Street Hospital, London, UK</affiliation></author><author><persName><forename type="first">Eric</forename><surname>Rosenthal</surname></persName><affiliation>Evelina Children's Hospital, London, UK</affiliation></author></analytic><monogr><title level="j">Heart</title><title level="j" type="abbrev">Heart</title><idno type="pISSN">1355-6037</idno><idno type="eISSN">1468-201X</idno><imprint><publisher>BMJ Publishing Group Ltd and British Cardiovascular Society</publisher><date type="published" when="2012-02-01"></date><biblScope unit="volume">98</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="202">202</biblScope></imprint></monogr><idno type="istex">3821817595BC87C721CAE24E19BDA7CAAC0A7B53</idno><idno type="DOI">10.1136/heartjnl-2011-300269</idno><idno type="href">heartjnl-98-202.pdf</idno><idno type="ArticleID">heartjnl-2011-300269</idno><idno type="PMID">21917661</idno><idno type="local">heartjnl;98/3/202</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2011-09-13</date></creation><langUsage><language ident="en">en</language></langUsage><abstract><p>Objective The aim of this study was to examine the accuracy in predicting pathway location in children with Wolff–Parkinson–White syndrome for each of seven published algorithms. Patients and interventions ECGs from 100 consecutive children with Wolff–Parkinson–White syndrome undergoing electrophysiological study were analysed by six investigators using seven published algorithms, six of which had been developed in adult patients. Main outcome measures Accuracy and concordance of predictions were adjusted for the number of pathway locations. Results Accessory pathways were left-sided in 49, septal in 20 and right-sided in 31 children. Overall accuracy of prediction was 30–49% for the exact location and 61–68% including adjacent locations. Concordance between investigators varied between 41% and 86%. No algorithm was better at predicting septal pathways (accuracy 5–35%, improving to 40–78% including adjacent locations), but one was significantly worse. Predictive accuracy was 24–53% for the exact location of right-sided pathways (50–71% including adjacent locations) and 32–55% for the exact location of left-sided pathways (58–73% including adjacent locations). Conclusions All algorithms were less accurate in our hands than in other authors' own assessment. None performed well in identifying midseptal or right anteroseptal accessory pathway locations.</p></abstract><textClass><keywords scheme="keyword"><list><head>Keywords</head><item><term>Wolff–Parkinson–White syndrome</term></item><item><term>paediatrics</term></item><item><term>electrophysiology</term></item><item><term>electrocardiography</term></item><item><term>paediatric electrophysiology</term></item><item><term>paediatric arrythmias</term></item><item><term>congenital heart disease</term></item><item><term>paediatric cardiology</term></item><item><term>embryology</term></item><item><term>autonomic defibrillator</term></item><item><term>spectral analysis</term></item><item><term>sinus node function</term></item><item><term>autonomic nervous system</term></item><item><term>transplantation</term></item><item><term>congenital—paediatric</term></item><item><term>congenital—adult</term></item><item><term>radiofrequency catheter ablation</term></item><item><term>pacing</term></item><item><term>arrhythmias</term></item><item><term>cardiac arrhythmias</term></item><item><term>muscular dystrophy and cardiac involvement</term></item><item><term>catheter ablation</term></item><item><term>cardiac electrophysiology</term></item><item><term>mitochondrial cardiomyopathy</term></item><item><term>sudden cardiac death</term></item><item><term>cardiomyopathy</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2011-09-13">Created</change><change when="2012-02-01">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/3821817595BC87C721CAE24E19BDA7CAAC0A7B53/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="corpus bmj" wicri:toSee="no header"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="no"</istex:xmlDeclaration><istex:docType PUBLIC="-//NLM//DTD Journal Archiving and Interchange DTD v2.3 20070202//EN" URI="archivearticle.dtd" name="istex:docType"></istex:docType><istex:document><article article-type="research-article"><front><journal-meta><journal-id journal-id-type="hwp">heartjnl</journal-id><journal-id journal-id-type="nlm-ta">Heart</journal-id><journal-id journal-id-type="publisher-id">heart</journal-id><journal-title>Heart</journal-title><abbrev-journal-title abbrev-type="publisher">Heart</abbrev-journal-title><abbrev-journal-title>Heart</abbrev-journal-title><issn pub-type="ppub">1355-6037</issn><issn pub-type="epub">1468-201X</issn><publisher><publisher-name>BMJ Publishing Group Ltd and British Cardiovascular Society</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">heartjnl-2011-300269</article-id><article-id pub-id-type="doi">10.1136/heartjnl-2011-300269</article-id><article-id pub-id-type="other">heartjnl;98/3/202</article-id><article-id pub-id-type="other">heartjnl;heartjnl-2011-300269</article-id><article-id pub-id-type="pmid">21917661</article-id><article-id pub-id-type="other">202</article-id><article-id pub-id-type="other">heartjnl-2011-300269</article-id><article-categories><subj-group subj-group-type="heading"><subject>Heart rhythm disorders</subject></subj-group><series-title>Original article</series-title></article-categories><title-group><article-title>Accuracy of algorithms to predict accessory pathway location in children with Wolff–Parkinson–White syndrome</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Wren</surname><given-names>Christopher</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Vogel</surname><given-names>Melanie</given-names></name><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Lord</surname><given-names>Stephen</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Abrams</surname><given-names>Dominic</given-names></name><xref ref-type="aff" rid="aff3">3</xref><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name><surname>Bourke</surname><given-names>John</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Rees</surname><given-names>Philip</given-names></name><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author"><name><surname>Rosenthal</surname><given-names>Eric</given-names></name><xref ref-type="aff" rid="aff5">5</xref></contrib></contrib-group><aff id="aff1"><label>1</label>Freeman Hospital, Newcastle upon Tyne, UK</aff><aff id="aff2"><label>2</label>Justus Liebig University, Giessen, Germany</aff><aff id="aff3"><label>3</label>Great Ormond Street Hospital, London, UK</aff><aff id="aff4"><label>4</label>St. Bartholomew's Hospital, London, UK</aff><aff id="aff5"><label>5</label>Evelina Children's Hospital, London, UK</aff><author-notes><corresp><label>Correspondence to</label> Dr Christopher Wren, Department of Paediatric Cardiology, Freeman Hospital, Newcastle upon Tyne NE3 5EL, UK; <email>christopher.wren@nuth.nhs.uk</email></corresp></author-notes><pub-date pub-type="epub-original"><day>13</day><month>9</month><year>2011</year></pub-date><pub-date pub-type="ppub"><day>1</day><month>2</month><year>2012</year></pub-date><pub-date pub-type="epub"><day>13</day><month>9</month><year>2011</year></pub-date><volume>98</volume><volume-id pub-id-type="other">98</volume-id><volume-id pub-id-type="other">98</volume-id><issue>3</issue><issue-id pub-id-type="other">heartjnl;98/3</issue-id><issue-id pub-id-type="other">3</issue-id><issue-id pub-id-type="other">98/3</issue-id><fpage>202</fpage><history><date date-type="accepted"><day>9</day><month>8</month><year>2011</year></date></history><permissions><copyright-statement>© 2011, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</copyright-statement><copyright-year>2011</copyright-year></permissions><self-uri content-type="pdf" xlink:role="full-text" xlink:href="heartjnl-98-202.pdf"></self-uri><abstract><sec><title>Objective</title><p>The aim of this study was to examine the accuracy in predicting pathway location in children with Wolff–Parkinson–White syndrome for each of seven published algorithms.</p></sec><sec><title>Patients and interventions</title><p>ECGs from 100 consecutive children with Wolff–Parkinson–White syndrome undergoing electrophysiological study were analysed by six investigators using seven published algorithms, six of which had been developed in adult patients.</p></sec><sec><title>Main outcome measures</title><p>Accuracy and concordance of predictions were adjusted for the number of pathway locations.</p></sec><sec><title>Results</title><p>Accessory pathways were left-sided in 49, septal in 20 and right-sided in 31 children. Overall accuracy of prediction was 30–49% for the exact location and 61–68% including adjacent locations. Concordance between investigators varied between 41% and 86%. No algorithm was better at predicting septal pathways (accuracy 5–35%, improving to 40–78% including adjacent locations), but one was significantly worse. Predictive accuracy was 24–53% for the exact location of right-sided pathways (50–71% including adjacent locations) and 32–55% for the exact location of left-sided pathways (58–73% including adjacent locations).</p></sec><sec><title>Conclusions</title><p>All algorithms were less accurate in our hands than in other authors' own assessment. None performed well in identifying midseptal or right anteroseptal accessory pathway locations.</p></sec></abstract><kwd-group><kwd>Wolff–Parkinson–White syndrome</kwd><kwd>paediatrics</kwd><kwd>electrophysiology</kwd><kwd>electrocardiography</kwd><kwd>paediatric electrophysiology</kwd><kwd>paediatric arrythmias</kwd><kwd>congenital heart disease</kwd><kwd>paediatric cardiology</kwd><kwd>embryology</kwd><kwd>autonomic defibrillator</kwd><kwd>spectral analysis</kwd><kwd>sinus node function</kwd><kwd>autonomic nervous system</kwd><kwd>transplantation</kwd><kwd>congenital—paediatric</kwd><kwd>congenital—adult</kwd><kwd>radiofrequency catheter ablation</kwd><kwd>pacing</kwd><kwd>arrhythmias</kwd><kwd>cardiac arrhythmias</kwd><kwd>muscular dystrophy and cardiac involvement</kwd><kwd>catheter ablation</kwd><kwd>cardiac electrophysiology</kwd><kwd>mitochondrial cardiomyopathy</kwd><kwd>sudden cardiac death</kwd><kwd>cardiomyopathy</kwd></kwd-group></article-meta></front></article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo><partName>Original article</partName><title>Accuracy of algorithms to predict accessory pathway location in children with Wolff–Parkinson–White syndrome</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><partName>Original article</partName><title>Accuracy of algorithms to predict accessory pathway location in children with Wolff–Parkinson–White syndrome</title></titleInfo><name type="personal" displayLabel="corresp"><namePart type="given">Christopher</namePart><namePart type="family">Wren</namePart><affiliation>Freeman Hospital, Newcastle upon Tyne, UK</affiliation><affiliation>E-mail: christopher.wren@nuth.nhs.uk</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Melanie</namePart><namePart type="family">Vogel</namePart><affiliation>Justus Liebig University, Giessen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Stephen</namePart><namePart type="family">Lord</namePart><affiliation>Freeman Hospital, Newcastle upon Tyne, UK</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Dominic</namePart><namePart type="family">Abrams</namePart><affiliation>Great Ormond Street Hospital, London, UK</affiliation><affiliation>St. Bartholomew's Hospital, London, UK</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">John</namePart><namePart type="family">Bourke</namePart><affiliation>Freeman Hospital, Newcastle upon Tyne, UK</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Philip</namePart><namePart type="family">Rees</namePart><affiliation>Great Ormond Street Hospital, London, UK</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Eric</namePart><namePart type="family">Rosenthal</namePart><affiliation>Evelina Children's Hospital, London, UK</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="research-article"></genre><originInfo><publisher>BMJ Publishing Group Ltd and British Cardiovascular Society</publisher><dateIssued encoding="w3cdtf">2012-02-01</dateIssued><dateCreated encoding="w3cdtf">2011-09-13</dateCreated><copyrightDate encoding="w3cdtf">2011</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract>Objective The aim of this study was to examine the accuracy in predicting pathway location in children with Wolff–Parkinson–White syndrome for each of seven published algorithms. Patients and interventions ECGs from 100 consecutive children with Wolff–Parkinson–White syndrome undergoing electrophysiological study were analysed by six investigators using seven published algorithms, six of which had been developed in adult patients. Main outcome measures Accuracy and concordance of predictions were adjusted for the number of pathway locations. Results Accessory pathways were left-sided in 49, septal in 20 and right-sided in 31 children. Overall accuracy of prediction was 30–49% for the exact location and 61–68% including adjacent locations. Concordance between investigators varied between 41% and 86%. No algorithm was better at predicting septal pathways (accuracy 5–35%, improving to 40–78% including adjacent locations), but one was significantly worse. Predictive accuracy was 24–53% for the exact location of right-sided pathways (50–71% including adjacent locations) and 32–55% for the exact location of left-sided pathways (58–73% including adjacent locations). Conclusions All algorithms were less accurate in our hands than in other authors' own assessment. None performed well in identifying midseptal or right anteroseptal accessory pathway locations.</abstract><subject><genre>Keywords</genre><topic>Wolff–Parkinson–White syndrome</topic><topic>paediatrics</topic><topic>electrophysiology</topic><topic>electrocardiography</topic><topic>paediatric electrophysiology</topic><topic>paediatric arrythmias</topic><topic>congenital heart disease</topic><topic>paediatric cardiology</topic><topic>embryology</topic><topic>autonomic defibrillator</topic><topic>spectral analysis</topic><topic>sinus node function</topic><topic>autonomic nervous system</topic><topic>transplantation</topic><topic>congenital—paediatric</topic><topic>congenital—adult</topic><topic>radiofrequency catheter ablation</topic><topic>pacing</topic><topic>arrhythmias</topic><topic>cardiac arrhythmias</topic><topic>muscular dystrophy and cardiac involvement</topic><topic>catheter ablation</topic><topic>cardiac electrophysiology</topic><topic>mitochondrial cardiomyopathy</topic><topic>sudden cardiac death</topic><topic>cardiomyopathy</topic></subject><relatedItem type="host"><titleInfo><title>Heart</title></titleInfo><titleInfo type="abbreviated"><title>Heart</title></titleInfo><genre type="Journal">journal</genre><identifier type="ISSN">1355-6037</identifier><identifier type="eISSN">1468-201X</identifier><identifier type="PublisherID">heart</identifier><identifier type="PublisherID-hwp">heartjnl</identifier><identifier type="PublisherID-nlm-ta">Heart</identifier><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>98</number></detail><detail type="issue"><caption>no.</caption><number>3</number></detail><extent unit="pages"><start>202</start></extent></part></relatedItem><identifier type="istex">3821817595BC87C721CAE24E19BDA7CAAC0A7B53</identifier><identifier type="DOI">10.1136/heartjnl-2011-300269</identifier><identifier type="href">heartjnl-98-202.pdf</identifier><identifier type="ArticleID">heartjnl-2011-300269</identifier><identifier type="PMID">21917661</identifier><identifier type="local">heartjnl;98/3/202</identifier><accessCondition type="use and reproduction" contentType="copyright">© 2011, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</accessCondition><recordInfo><recordContentSource>BMJ</recordContentSource></recordInfo></mods></metadata><annexes><json:item><original>true</original><mimetype>image/jpeg</mimetype><extension>jpeg</extension><uri>https://api.istex.fr/document/3821817595BC87C721CAE24E19BDA7CAAC0A7B53/annexes/jpeg</uri></json:item></annexes><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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