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Efficacy of desensitizing dentifrices to occlude dentinal tubules

Identifieur interne : 001489 ( Main/Corpus ); précédent : 001488; suivant : 001490

Efficacy of desensitizing dentifrices to occlude dentinal tubules

Auteurs : Maria Davies ; Elizabeth M. Paice ; Sian B. Jones ; Sam Leary ; Andrew R. Curtis ; Nicola X. West

Source :

RBID : ISTEX:94A9095046DC068045EC2EFCB7640EF860CFA351

English descriptors

Abstract

Davies M, Paice EM, Jones SB, Leary S, Curtis AR, West NX. Efficacy of desensitizing dentifrices to occlude dentinal tubules. 
 Eur J Oral Sci 2011; 119: 497–503. © 2011 Eur J Oral Sci Dentine hypersensitivity occurs when patent dentinal tubules are subjected to external stimuli, with pain being reduced by products that occlude tubules. This study compared the efficacy of a recently developed arginine‐containing dentifrice, two established strontium‐based products, and a fluoride control to occlude tubules when subjected to acid challenge. Dentine specimens with patent tubules were divided into four groups that were treated with a slurry consisting of one of the pastes mixed with stimulated human saliva. Treated specimens were further subdivided and soaked in 0.3% citric acid for 10 s, 30 s, 2 min, 5 min or 10 min. Tubule occlusion on representative scanning electron microscopy images was scored by blind review. All three desensitizing pastes offered good tubule occlusion, which was maintained to varying degrees following acidic challenge. After immersion in acid for 10 and 30 s, the strontium acetate‐ and arginine‐containing pastes almost fully occluded tubules, but only the strontium acetate paste retained this level of occlusion after immersion in acid for 2 min, with strong statistical evidence that this paste occluded more tubules than the other pastes after immersion in acid for 2 or 5 min. This suggests that strontium acetate pastes may be the most effective at reducing dentine hypersensitivity.

Url:
DOI: 10.1111/j.1600-0722.2011.00872.x

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ISTEX:94A9095046DC068045EC2EFCB7640EF860CFA351

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<keyword xml:id="k1">arginine</keyword>
<keyword xml:id="k2">citric acid</keyword>
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<i>Davies M, Paice EM, Jones SB, Leary S, Curtis AR, West NX. Efficacy of desensitizing dentifrices to occlude dentinal tubules.</i>
<i>Eur J Oral Sci 2011; 119: 497–503. © 2011 Eur J Oral Sci</i>
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<p>Dentine hypersensitivity occurs when patent dentinal tubules are subjected to external stimuli, with pain being reduced by products that occlude tubules. This study compared the efficacy of a recently developed arginine‐containing dentifrice, two established strontium‐based products, and a fluoride control to occlude tubules when subjected to acid challenge. Dentine specimens with patent tubules were divided into four groups that were treated with a slurry consisting of one of the pastes mixed with stimulated human saliva. Treated specimens were further subdivided and soaked in 0.3% citric acid for 10 s, 30 s, 2 min, 5 min or 10 min. Tubule occlusion on representative scanning electron microscopy images was scored by blind review. All three desensitizing pastes offered good tubule occlusion, which was maintained to varying degrees following acidic challenge. After immersion in acid for 10 and 30 s, the strontium acetate‐ and arginine‐containing pastes almost fully occluded tubules, but only the strontium acetate paste retained this level of occlusion after immersion in acid for 2 min, with strong statistical evidence that this paste occluded more tubules than the other pastes after immersion in acid for 2 or 5 min. This suggests that strontium acetate pastes may be the most effective at reducing dentine hypersensitivity.</p>
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<title>Efficacy of desensitizing dentifrices to occlude dentinal tubules</title>
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<namePart type="given">Maria</namePart>
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<edition>Accepted for publication August 2011</edition>
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<abstract lang="en">Davies M, Paice EM, Jones SB, Leary S, Curtis AR, West NX. Efficacy of desensitizing dentifrices to occlude dentinal tubules. 
 Eur J Oral Sci 2011; 119: 497–503. © 2011 Eur J Oral Sci Dentine hypersensitivity occurs when patent dentinal tubules are subjected to external stimuli, with pain being reduced by products that occlude tubules. This study compared the efficacy of a recently developed arginine‐containing dentifrice, two established strontium‐based products, and a fluoride control to occlude tubules when subjected to acid challenge. Dentine specimens with patent tubules were divided into four groups that were treated with a slurry consisting of one of the pastes mixed with stimulated human saliva. Treated specimens were further subdivided and soaked in 0.3% citric acid for 10 s, 30 s, 2 min, 5 min or 10 min. Tubule occlusion on representative scanning electron microscopy images was scored by blind review. All three desensitizing pastes offered good tubule occlusion, which was maintained to varying degrees following acidic challenge. After immersion in acid for 10 and 30 s, the strontium acetate‐ and arginine‐containing pastes almost fully occluded tubules, but only the strontium acetate paste retained this level of occlusion after immersion in acid for 2 min, with strong statistical evidence that this paste occluded more tubules than the other pastes after immersion in acid for 2 or 5 min. This suggests that strontium acetate pastes may be the most effective at reducing dentine hypersensitivity.</abstract>
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<genre>Keywords</genre>
<topic>arginine</topic>
<topic>citric acid</topic>
<topic>dentine hypersensitivity</topic>
<topic>dentine tubules</topic>
<topic>strontium</topic>
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<title>European Journal of Oral Sciences</title>
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<identifier type="ISSN">0909-8836</identifier>
<identifier type="eISSN">1600-0722</identifier>
<identifier type="DOI">10.1111/(ISSN)1600-0722</identifier>
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<date>2011</date>
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<caption>vol.</caption>
<number>119</number>
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<number>6</number>
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