Efficacy of desensitizing dentifrices to occlude dentinal tubules
Identifieur interne : 001489 ( Main/Corpus ); précédent : 001488; suivant : 001490Efficacy of desensitizing dentifrices to occlude dentinal tubules
Auteurs : Maria Davies ; Elizabeth M. Paice ; Sian B. Jones ; Sam Leary ; Andrew R. Curtis ; Nicola X. WestSource :
- European Journal of Oral Sciences [ 0909-8836 ] ; 2011-12.
English descriptors
Abstract
Davies M, Paice EM, Jones SB, Leary S, Curtis AR, West NX. Efficacy of desensitizing dentifrices to occlude dentinal tubules.
Eur J Oral Sci 2011; 119: 497–503. © 2011 Eur J Oral Sci Dentine hypersensitivity occurs when patent dentinal tubules are subjected to external stimuli, with pain being reduced by products that occlude tubules. This study compared the efficacy of a recently developed arginine‐containing dentifrice, two established strontium‐based products, and a fluoride control to occlude tubules when subjected to acid challenge. Dentine specimens with patent tubules were divided into four groups that were treated with a slurry consisting of one of the pastes mixed with stimulated human saliva. Treated specimens were further subdivided and soaked in 0.3% citric acid for 10 s, 30 s, 2 min, 5 min or 10 min. Tubule occlusion on representative scanning electron microscopy images was scored by blind review. All three desensitizing pastes offered good tubule occlusion, which was maintained to varying degrees following acidic challenge. After immersion in acid for 10 and 30 s, the strontium acetate‐ and arginine‐containing pastes almost fully occluded tubules, but only the strontium acetate paste retained this level of occlusion after immersion in acid for 2 min, with strong statistical evidence that this paste occluded more tubules than the other pastes after immersion in acid for 2 or 5 min. This suggests that strontium acetate pastes may be the most effective at reducing dentine hypersensitivity.
Url:
DOI: 10.1111/j.1600-0722.2011.00872.x
Links to Exploration step
ISTEX:94A9095046DC068045EC2EFCB7640EF860CFA351Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Efficacy of desensitizing dentifrices to occlude dentinal tubules</title><author><name sortKey="Davies, Maria" sort="Davies, Maria" uniqKey="Davies M" first="Maria" last="Davies">Maria Davies</name><affiliation><mods:affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</mods:affiliation></affiliation></author><author><name sortKey="Paice, Elizabeth M" sort="Paice, Elizabeth M" uniqKey="Paice E" first="Elizabeth M." last="Paice">Elizabeth M. Paice</name><affiliation><mods:affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</mods:affiliation></affiliation></author><author><name sortKey="Jones, Sian B" sort="Jones, Sian B" uniqKey="Jones S" first="Sian B." last="Jones">Sian B. Jones</name><affiliation><mods:affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</mods:affiliation></affiliation></author><author><name sortKey="Leary, Sam" sort="Leary, Sam" uniqKey="Leary S" first="Sam" last="Leary">Sam Leary</name><affiliation><mods:affiliation>School of Oral and Dental Science, University of Bristol, Bristol, UK</mods:affiliation></affiliation></author><author><name sortKey="Curtis, Andrew R" sort="Curtis, Andrew R" uniqKey="Curtis A" first="Andrew R." last="Curtis">Andrew R. Curtis</name><affiliation><mods:affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</mods:affiliation></affiliation></author><author><name sortKey="West, Nicola X" sort="West, Nicola X" uniqKey="West N" first="Nicola X." last="West">Nicola X. West</name><affiliation><mods:affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:94A9095046DC068045EC2EFCB7640EF860CFA351</idno><date when="2011" year="2011">2011</date><idno type="doi">10.1111/j.1600-0722.2011.00872.x</idno><idno type="url">https://api.istex.fr/document/94A9095046DC068045EC2EFCB7640EF860CFA351/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">001489</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Efficacy of desensitizing dentifrices to occlude dentinal tubules</title><author><name sortKey="Davies, Maria" sort="Davies, Maria" uniqKey="Davies M" first="Maria" last="Davies">Maria Davies</name><affiliation><mods:affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</mods:affiliation></affiliation></author><author><name sortKey="Paice, Elizabeth M" sort="Paice, Elizabeth M" uniqKey="Paice E" first="Elizabeth M." last="Paice">Elizabeth M. Paice</name><affiliation><mods:affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</mods:affiliation></affiliation></author><author><name sortKey="Jones, Sian B" sort="Jones, Sian B" uniqKey="Jones S" first="Sian B." last="Jones">Sian B. Jones</name><affiliation><mods:affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</mods:affiliation></affiliation></author><author><name sortKey="Leary, Sam" sort="Leary, Sam" uniqKey="Leary S" first="Sam" last="Leary">Sam Leary</name><affiliation><mods:affiliation>School of Oral and Dental Science, University of Bristol, Bristol, UK</mods:affiliation></affiliation></author><author><name sortKey="Curtis, Andrew R" sort="Curtis, Andrew R" uniqKey="Curtis A" first="Andrew R." last="Curtis">Andrew R. Curtis</name><affiliation><mods:affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</mods:affiliation></affiliation></author><author><name sortKey="West, Nicola X" sort="West, Nicola X" uniqKey="West N" first="Nicola X." last="West">Nicola X. West</name><affiliation><mods:affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">European Journal of Oral Sciences</title><idno type="ISSN">0909-8836</idno><idno type="eISSN">1600-0722</idno><imprint><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2011-12">2011-12</date><biblScope unit="volume">119</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="497">497</biblScope><biblScope unit="page" to="503">503</biblScope></imprint><idno type="ISSN">0909-8836</idno></series><idno type="istex">94A9095046DC068045EC2EFCB7640EF860CFA351</idno><idno type="DOI">10.1111/j.1600-0722.2011.00872.x</idno><idno type="ArticleID">EOS872</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0909-8836</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>arginine</term><term>citric acid</term><term>dentine hypersensitivity</term><term>dentine tubules</term><term>strontium</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Davies M, Paice EM, Jones SB, Leary S, Curtis AR, West NX. Efficacy of desensitizing dentifrices to occlude dentinal tubules.
Eur J Oral Sci 2011; 119: 497–503. © 2011 Eur J Oral Sci Dentine hypersensitivity occurs when patent dentinal tubules are subjected to external stimuli, with pain being reduced by products that occlude tubules. This study compared the efficacy of a recently developed arginine‐containing dentifrice, two established strontium‐based products, and a fluoride control to occlude tubules when subjected to acid challenge. Dentine specimens with patent tubules were divided into four groups that were treated with a slurry consisting of one of the pastes mixed with stimulated human saliva. Treated specimens were further subdivided and soaked in 0.3% citric acid for 10 s, 30 s, 2 min, 5 min or 10 min. Tubule occlusion on representative scanning electron microscopy images was scored by blind review. All three desensitizing pastes offered good tubule occlusion, which was maintained to varying degrees following acidic challenge. After immersion in acid for 10 and 30 s, the strontium acetate‐ and arginine‐containing pastes almost fully occluded tubules, but only the strontium acetate paste retained this level of occlusion after immersion in acid for 2 min, with strong statistical evidence that this paste occluded more tubules than the other pastes after immersion in acid for 2 or 5 min. This suggests that strontium acetate pastes may be the most effective at reducing dentine hypersensitivity.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Maria Davies</name><affiliations><json:string>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</json:string></affiliations></json:item><json:item><name>Elizabeth M. Paice</name><affiliations><json:string>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</json:string></affiliations></json:item><json:item><name>Sian B. Jones</name><affiliations><json:string>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</json:string></affiliations></json:item><json:item><name>Sam Leary</name><affiliations><json:string>School of Oral and Dental Science, University of Bristol, Bristol, UK</json:string></affiliations></json:item><json:item><name>Andrew R. Curtis</name><affiliations><json:string>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</json:string></affiliations></json:item><json:item><name>Nicola X. West</name><affiliations><json:string>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>arginine</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>citric acid</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>dentine hypersensitivity</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>dentine tubules</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>strontium</value></json:item></subject><articleId><json:string>EOS872</json:string></articleId><language><json:string>eng</json:string></language><abstract>Davies M, Paice EM, Jones SB, Leary S, Curtis AR, West NX. Efficacy of desensitizing dentifrices to occlude dentinal tubules.
Eur J Oral Sci 2011; 119: 497–503. © 2011 Eur J Oral Sci Dentine hypersensitivity occurs when patent dentinal tubules are subjected to external stimuli, with pain being reduced by products that occlude tubules. This study compared the efficacy of a recently developed arginine‐containing dentifrice, two established strontium‐based products, and a fluoride control to occlude tubules when subjected to acid challenge. Dentine specimens with patent tubules were divided into four groups that were treated with a slurry consisting of one of the pastes mixed with stimulated human saliva. Treated specimens were further subdivided and soaked in 0.3% citric acid for 10 s, 30 s, 2 min, 5 min or 10 min. Tubule occlusion on representative scanning electron microscopy images was scored by blind review. All three desensitizing pastes offered good tubule occlusion, which was maintained to varying degrees following acidic challenge. After immersion in acid for 10 and 30 s, the strontium acetate‐ and arginine‐containing pastes almost fully occluded tubules, but only the strontium acetate paste retained this level of occlusion after immersion in acid for 2 min, with strong statistical evidence that this paste occluded more tubules than the other pastes after immersion in acid for 2 or 5 min. This suggests that strontium acetate pastes may be the most effective at reducing dentine hypersensitivity.</abstract><qualityIndicators><score>7.723</score><pdfVersion>1.3</pdfVersion><pdfPageSize>595.276 x 799.37 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>5</keywordCount><abstractCharCount>1527</abstractCharCount><pdfWordCount>4975</pdfWordCount><pdfCharCount>30972</pdfCharCount><pdfPageCount>7</pdfPageCount><abstractWordCount>229</abstractWordCount></qualityIndicators><title>Efficacy of desensitizing dentifrices to occlude dentinal tubules</title><genre><json:string>article</json:string></genre><host><volume>119</volume><publisherId><json:string>EOS</json:string></publisherId><pages><total>7</total><last>503</last><first>497</first></pages><issn><json:string>0909-8836</json:string></issn><issue>6</issue><genre><json:string>Journal</json:string></genre><language><json:string>unknown</json:string></language><eissn><json:string>1600-0722</json:string></eissn><title>European Journal of Oral Sciences</title><doi><json:string>10.1111/(ISSN)1600-0722</json:string></doi></host><publicationDate>2011</publicationDate><copyrightDate>2011</copyrightDate><doi><json:string>10.1111/j.1600-0722.2011.00872.x</json:string></doi><id>94A9095046DC068045EC2EFCB7640EF860CFA351</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/94A9095046DC068045EC2EFCB7640EF860CFA351/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/94A9095046DC068045EC2EFCB7640EF860CFA351/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/94A9095046DC068045EC2EFCB7640EF860CFA351/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Efficacy of desensitizing dentifrices to occlude dentinal tubules</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><availability><p>WILEY</p></availability><date>2011</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Efficacy of desensitizing dentifrices to occlude dentinal tubules</title><author><persName><forename type="first">Maria</forename><surname>Davies</surname></persName><affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</affiliation></author><author><persName><forename type="first">Elizabeth M.</forename><surname>Paice</surname></persName><affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</affiliation></author><author><persName><forename type="first">Sian B.</forename><surname>Jones</surname></persName><affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</affiliation></author><author><persName><forename type="first">Sam</forename><surname>Leary</surname></persName><affiliation>School of Oral and Dental Science, University of Bristol, Bristol, UK</affiliation></author><author><persName><forename type="first">Andrew R.</forename><surname>Curtis</surname></persName><affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</affiliation></author><author><persName><forename type="first">Nicola X.</forename><surname>West</surname></persName><affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</affiliation></author></analytic><monogr><title level="j">European Journal of Oral Sciences</title><idno type="pISSN">0909-8836</idno><idno type="eISSN">1600-0722</idno><idno type="DOI">10.1111/(ISSN)1600-0722</idno><imprint><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2011-12"></date><biblScope unit="volume">119</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="497">497</biblScope><biblScope unit="page" to="503">503</biblScope></imprint></monogr><idno type="istex">94A9095046DC068045EC2EFCB7640EF860CFA351</idno><idno type="DOI">10.1111/j.1600-0722.2011.00872.x</idno><idno type="ArticleID">EOS872</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2011</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Davies M, Paice EM, Jones SB, Leary S, Curtis AR, West NX. Efficacy of desensitizing dentifrices to occlude dentinal tubules.
Eur J Oral Sci 2011; 119: 497–503. © 2011 Eur J Oral Sci Dentine hypersensitivity occurs when patent dentinal tubules are subjected to external stimuli, with pain being reduced by products that occlude tubules. This study compared the efficacy of a recently developed arginine‐containing dentifrice, two established strontium‐based products, and a fluoride control to occlude tubules when subjected to acid challenge. Dentine specimens with patent tubules were divided into four groups that were treated with a slurry consisting of one of the pastes mixed with stimulated human saliva. Treated specimens were further subdivided and soaked in 0.3% citric acid for 10 s, 30 s, 2 min, 5 min or 10 min. Tubule occlusion on representative scanning electron microscopy images was scored by blind review. All three desensitizing pastes offered good tubule occlusion, which was maintained to varying degrees following acidic challenge. After immersion in acid for 10 and 30 s, the strontium acetate‐ and arginine‐containing pastes almost fully occluded tubules, but only the strontium acetate paste retained this level of occlusion after immersion in acid for 2 min, with strong statistical evidence that this paste occluded more tubules than the other pastes after immersion in acid for 2 or 5 min. This suggests that strontium acetate pastes may be the most effective at reducing dentine hypersensitivity.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>arginine</term></item><item><term>citric acid</term></item><item><term>dentine hypersensitivity</term></item><item><term>dentine tubules</term></item><item><term>strontium</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2011-12">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/94A9095046DC068045EC2EFCB7640EF860CFA351/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Publishing Ltd</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1600-0722</doi><issn type="print">0909-8836</issn><issn type="electronic">1600-0722</issn><idGroup><id type="product" value="EOS"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="EUROPEAN JOURNAL OF ORAL SCIENCES">European Journal of Oral Sciences</title></titleGroup></publicationMeta><publicationMeta level="part" position="12106"><doi origin="wiley">10.1111/eos.2011.119.issue-6</doi><numberingGroup><numbering type="journalVolume" number="119">119</numbering><numbering type="journalIssue" number="6">6</numbering></numberingGroup><coverDate startDate="2011-12">December 2011</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="13" status="forIssue"><doi origin="wiley">10.1111/j.1600-0722.2011.00872.x</doi><idGroup><id type="unit" value="EOS872"></id></idGroup><countGroup><count type="pageTotal" number="7"></count></countGroup><titleGroup><title type="tocHeading1">Original articles</title></titleGroup><copyright>© 2011 Eur J Oral Sci</copyright><eventGroup><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:3.0 mode:FullText" date="2011-11-23"></event><event type="publishedOnlineEarlyUnpaginated" date="2011-10-11"></event><event type="firstOnline" date="2011-10-11"></event><event type="publishedOnlineFinalForm" date="2011-11-23"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-24"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-16"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="497">497</numbering><numbering type="pageLast" number="503">503</numbering></numberingGroup><correspondenceTo>Nicola X. West, Clinical Trials Unit, Bristol Dental School, Lower Maudlin Street, Bristol BS1 2LY, UK
Telefax: +44–117–3424100
E‐mail: <email>n.x.west@bristol.ac.uk</email></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:EOS.EOS872.pdf"></link></linkGroup></publicationMeta><contentMeta><unparsedEditorialHistory>Accepted for publication August 2011</unparsedEditorialHistory><countGroup><count type="figureTotal" number="2"></count><count type="tableTotal" number="2"></count></countGroup><titleGroup><title type="main">Efficacy of desensitizing dentifrices to occlude dentinal tubules</title><title type="shortAuthors"><i>Davies et al.</i></title><title type="short"><i>Efficacy of dentinal tubule occlusion</i></title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1"><personName><givenNames>Maria</givenNames><familyName>Davies</familyName></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#a1"><personName><givenNames>Elizabeth M.</givenNames><familyName>Paice</familyName></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#a1"><personName><givenNames>Sian B.</givenNames><familyName>Jones</familyName></personName></creator><creator creatorRole="author" xml:id="cr4" affiliationRef="#a2"><personName><givenNames>Sam</givenNames><familyName>Leary</familyName></personName></creator><creator creatorRole="author" xml:id="cr5" affiliationRef="#a1"><personName><givenNames>Andrew R.</givenNames><familyName>Curtis</familyName></personName></creator><creator creatorRole="author" xml:id="cr6" affiliationRef="#a1"><personName><givenNames>Nicola X.</givenNames><familyName>West</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="a1"><unparsedAffiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</unparsedAffiliation></affiliation><affiliation xml:id="a2" countryCode="GB"><unparsedAffiliation>School of Oral and Dental Science, University of Bristol, Bristol, UK</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en"><keyword xml:id="k1">arginine</keyword><keyword xml:id="k2">citric acid</keyword><keyword xml:id="k3">dentine hypersensitivity</keyword><keyword xml:id="k4">dentine tubules</keyword><keyword xml:id="k5">strontium</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><p><i>Davies M, Paice EM, Jones SB, Leary S, Curtis AR, West NX. Efficacy of desensitizing dentifrices to occlude dentinal tubules.</i>
<i>Eur J Oral Sci 2011; 119: 497–503. © 2011 Eur J Oral Sci</i></p><p>Dentine hypersensitivity occurs when patent dentinal tubules are subjected to external stimuli, with pain being reduced by products that occlude tubules. This study compared the efficacy of a recently developed arginine‐containing dentifrice, two established strontium‐based products, and a fluoride control to occlude tubules when subjected to acid challenge. Dentine specimens with patent tubules were divided into four groups that were treated with a slurry consisting of one of the pastes mixed with stimulated human saliva. Treated specimens were further subdivided and soaked in 0.3% citric acid for 10 s, 30 s, 2 min, 5 min or 10 min. Tubule occlusion on representative scanning electron microscopy images was scored by blind review. All three desensitizing pastes offered good tubule occlusion, which was maintained to varying degrees following acidic challenge. After immersion in acid for 10 and 30 s, the strontium acetate‐ and arginine‐containing pastes almost fully occluded tubules, but only the strontium acetate paste retained this level of occlusion after immersion in acid for 2 min, with strong statistical evidence that this paste occluded more tubules than the other pastes after immersion in acid for 2 or 5 min. This suggests that strontium acetate pastes may be the most effective at reducing dentine hypersensitivity.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Efficacy of desensitizing dentifrices to occlude dentinal tubules</title></titleInfo><titleInfo type="abbreviated"><title>Efficacy of dentinal tubule occlusion</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Efficacy of desensitizing dentifrices to occlude dentinal tubules</title></titleInfo><name type="personal"><namePart type="given">Maria</namePart><namePart type="family">Davies</namePart><affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Elizabeth M.</namePart><namePart type="family">Paice</namePart><affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Sian B.</namePart><namePart type="family">Jones</namePart><affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Sam</namePart><namePart type="family">Leary</namePart><affiliation>School of Oral and Dental Science, University of Bristol, Bristol, UK</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Andrew R.</namePart><namePart type="family">Curtis</namePart><affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Nicola X.</namePart><namePart type="family">West</namePart><affiliation>Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2011-12</dateIssued><edition>Accepted for publication August 2011</edition><copyrightDate encoding="w3cdtf">2011</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">2</extent><extent unit="tables">2</extent></physicalDescription><abstract lang="en">Davies M, Paice EM, Jones SB, Leary S, Curtis AR, West NX. Efficacy of desensitizing dentifrices to occlude dentinal tubules.
Eur J Oral Sci 2011; 119: 497–503. © 2011 Eur J Oral Sci Dentine hypersensitivity occurs when patent dentinal tubules are subjected to external stimuli, with pain being reduced by products that occlude tubules. This study compared the efficacy of a recently developed arginine‐containing dentifrice, two established strontium‐based products, and a fluoride control to occlude tubules when subjected to acid challenge. Dentine specimens with patent tubules were divided into four groups that were treated with a slurry consisting of one of the pastes mixed with stimulated human saliva. Treated specimens were further subdivided and soaked in 0.3% citric acid for 10 s, 30 s, 2 min, 5 min or 10 min. Tubule occlusion on representative scanning electron microscopy images was scored by blind review. All three desensitizing pastes offered good tubule occlusion, which was maintained to varying degrees following acidic challenge. After immersion in acid for 10 and 30 s, the strontium acetate‐ and arginine‐containing pastes almost fully occluded tubules, but only the strontium acetate paste retained this level of occlusion after immersion in acid for 2 min, with strong statistical evidence that this paste occluded more tubules than the other pastes after immersion in acid for 2 or 5 min. This suggests that strontium acetate pastes may be the most effective at reducing dentine hypersensitivity.</abstract><subject lang="en"><genre>Keywords</genre><topic>arginine</topic><topic>citric acid</topic><topic>dentine hypersensitivity</topic><topic>dentine tubules</topic><topic>strontium</topic></subject><relatedItem type="host"><titleInfo><title>European Journal of Oral Sciences</title></titleInfo><genre type="Journal">journal</genre><identifier type="ISSN">0909-8836</identifier><identifier type="eISSN">1600-0722</identifier><identifier type="DOI">10.1111/(ISSN)1600-0722</identifier><identifier type="PublisherID">EOS</identifier><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>119</number></detail><detail type="issue"><caption>no.</caption><number>6</number></detail><extent unit="pages"><start>497</start><end>503</end><total>7</total></extent></part></relatedItem><identifier type="istex">94A9095046DC068045EC2EFCB7640EF860CFA351</identifier><identifier type="DOI">10.1111/j.1600-0722.2011.00872.x</identifier><identifier type="ArticleID">EOS872</identifier><accessCondition type="use and reproduction" contentType="copyright">© 2011 Eur J Oral Sci</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001489 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Corpus/biblio.hfd -nk 001489 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonV1
|flux= Main
|étape= Corpus
|type= RBID
|clé= ISTEX:94A9095046DC068045EC2EFCB7640EF860CFA351
|texte= Efficacy of desensitizing dentifrices to occlude dentinal tubules
}}
| This area was generated with Dilib version V0.6.23. |  |