Comparison of swallowing function in Parkinson's disease and progressive supranuclear palsy
Identifieur interne : 001478 ( Main/Corpus ); précédent : 001477; suivant : 001479Comparison of swallowing function in Parkinson's disease and progressive supranuclear palsy
Auteurs : Johnston ; June A. Castell ; Sharon Stumacher ; Amy Colcher ; R. Matthew Gideon ; Qun Li ; Donald O. CastellSource :
- Movement Disorders [ 0885-3185 ] ; 1997-05.
English descriptors
Abstract
Dysphagia is common in both Parkinson's disease (PD) and progressive supranuclear palsy (PSP). Although it is believed to be more common in PSP, there are no controlled data and no comparison of swallowing function between these two disorders. Our aim was to assess dysphagia and swallow function in patients with PSP and PD. Seven patients with PSP were matched to seven patients with PD on the basis of disease duration. Self‐rated dysphagia, movement disorder disability, modified barium swallow results, and abnormalities noted on manometry of the lower esophageal sphincter, esophageal body, upper esophageal sphincter, and pharynx were compared between the two groups. Neither severity nor duration of dysphagia differed between the two groups. Patients with PSP had a significantly greater degree of disability [median (range) Hoehn & Yahr score, 4 (3–5) vs. 2 (1–2); p < 0.002]. Manometric abnormalities were similar for the two groups. Oral‐phase abnormalities on modified barium swallow were significantly more frequent in PSP (four patients with PSP vs. no patients with PD; p < 0.005). Pharyngeal abnormalities did not differ. Modified barium‐swallow scores correalated well with self‐reported dysphagia severity for patients with PSP (r = 0.93; p < 0.05) but not for those with PD (r = 0.42; p = NS). The frequency of abnormalities noted during the oral phase was significantly increased in PSP. It is hypothesized that the sensory information conveyed due to this may account for the better correlation between symptoms and swallowing abnormalities and the belief that swallowing problems are more common in PSP.
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DOI: 10.1002/mds.870120310
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Castell</name><affiliation><mods:affiliation>Departments of Medicine, Graduate Hospital, Philadelphia, Pennsylvania, U.S.A.</mods:affiliation></affiliation></author><author><name sortKey="Stumacher, Sharon" sort="Stumacher, Sharon" uniqKey="Stumacher S" first="Sharon" last="Stumacher">Sharon Stumacher</name><affiliation><mods:affiliation>Speech/Language Pathology, Department of Neurology, Graduate Hospital, Philadelphia, Pennsylvania, U.S.A.</mods:affiliation></affiliation></author><author><name sortKey="Colcher, Amy" sort="Colcher, Amy" uniqKey="Colcher A" first="Amy" last="Colcher">Amy Colcher</name><affiliation><mods:affiliation>Departments of Medicine, Movement Disorders Clinic, Department of Neurology, Graduate Hospital, Philadelphia, Pennsylvania, U.S.A.</mods:affiliation></affiliation></author><author><name sortKey="Gideon, R Matthew" sort="Gideon, R Matthew" uniqKey="Gideon R" first="R. Matthew" last="Gideon">R. 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Although it is believed to be more common in PSP, there are no controlled data and no comparison of swallowing function between these two disorders. Our aim was to assess dysphagia and swallow function in patients with PSP and PD. Seven patients with PSP were matched to seven patients with PD on the basis of disease duration. Self‐rated dysphagia, movement disorder disability, modified barium swallow results, and abnormalities noted on manometry of the lower esophageal sphincter, esophageal body, upper esophageal sphincter, and pharynx were compared between the two groups. Neither severity nor duration of dysphagia differed between the two groups. Patients with PSP had a significantly greater degree of disability [median (range) Hoehn & Yahr score, 4 (3–5) vs. 2 (1–2); p < 0.002]. Manometric abnormalities were similar for the two groups. Oral‐phase abnormalities on modified barium swallow were significantly more frequent in PSP (four patients with PSP vs. no patients with PD; p < 0.005). Pharyngeal abnormalities did not differ. Modified barium‐swallow scores correalated well with self‐reported dysphagia severity for patients with PSP (r = 0.93; p < 0.05) but not for those with PD (r = 0.42; p = NS). The frequency of abnormalities noted during the oral phase was significantly increased in PSP. It is hypothesized that the sensory information conveyed due to this may account for the better correlation between symptoms and swallowing abnormalities and the belief that swallowing problems are more common in PSP.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Dr. Johnston</name><affiliations><json:string>Departments of Medicine, Graduate Hospital, Philadelphia, Pennsylvania, U.S.A.</json:string></affiliations></json:item><json:item><name>June A. 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Castell</name><affiliations><json:string>Departments of Medicine, Graduate Hospital, Philadelphia, Pennsylvania, U.S.A.</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Dysphagia</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Modified barium swallow</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Progressive supranuclear palsy</value></json:item></subject><articleId><json:string>MDS870120310</json:string></articleId><language><json:string>eng</json:string></language><abstract>Dysphagia is common in both Parkinson's disease (PD) and progressive supranuclear palsy (PSP). Although it is believed to be more common in PSP, there are no controlled data and no comparison of swallowing function between these two disorders. Our aim was to assess dysphagia and swallow function in patients with PSP and PD. Seven patients with PSP were matched to seven patients with PD on the basis of disease duration. Self‐rated dysphagia, movement disorder disability, modified barium swallow results, and abnormalities noted on manometry of the lower esophageal sphincter, esophageal body, upper esophageal sphincter, and pharynx were compared between the two groups. Neither severity nor duration of dysphagia differed between the two groups. Patients with PSP had a significantly greater degree of disability [median (range) Hoehn & Yahr score, 4 (3–5) vs. 2 (1–2); p > 0.002]. Manometric abnormalities were similar for the two groups. Oral‐phase abnormalities on modified barium swallow were significantly more frequent in PSP (four patients with PSP vs. no patients with PD; p > 0.005). Pharyngeal abnormalities did not differ. Modified barium‐swallow scores correalated well with self‐reported dysphagia severity for patients with PSP (r = 0.93; p > 0.05) but not for those with PD (r = 0.42; p = NS). The frequency of abnormalities noted during the oral phase was significantly increased in PSP. 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Although it is believed to be more common in PSP, there are no controlled data and no comparison of swallowing function between these two disorders. Our aim was to assess dysphagia and swallow function in patients with PSP and PD. Seven patients with PSP were matched to seven patients with PD on the basis of disease duration. Self‐rated dysphagia, movement disorder disability, modified barium swallow results, and abnormalities noted on manometry of the lower esophageal sphincter, esophageal body, upper esophageal sphincter, and pharynx were compared between the two groups. Neither severity nor duration of dysphagia differed between the two groups. Patients with PSP had a significantly greater degree of disability [median (range) Hoehn & Yahr score, 4 (3–5) vs. 2 (1–2); p < 0.002]. Manometric abnormalities were similar for the two groups. Oral‐phase abnormalities on modified barium swallow were significantly more frequent in PSP (four patients with PSP vs. no patients with PD; p < 0.005). Pharyngeal abnormalities did not differ. Modified barium‐swallow scores correalated well with self‐reported dysphagia severity for patients with PSP (r = 0.93; p < 0.05) but not for those with PD (r = 0.42; p = NS). The frequency of abnormalities noted during the oral phase was significantly increased in PSP. 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Matthew</givenNames><familyName>Gideon</familyName></personName></creator><creator xml:id="au6" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Qun</givenNames><familyName>Li</familyName></personName></creator><creator xml:id="au7" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Donald O.</givenNames><familyName>Castell</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="US" type="organization"><unparsedAffiliation>Departments of Medicine, Graduate Hospital, Philadelphia, Pennsylvania, U.S.A.</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="US" type="organization"><unparsedAffiliation>Speech/Language Pathology, Department of Neurology, Graduate Hospital, Philadelphia, Pennsylvania, U.S.A.</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="US" type="organization"><unparsedAffiliation>Departments of Medicine, Movement Disorders Clinic, Department of Neurology, Graduate Hospital, Philadelphia, Pennsylvania, U.S.A.</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">Dysphagia</keyword><keyword xml:id="kwd2">Modified barium swallow</keyword><keyword xml:id="kwd3">Parkinson's disease</keyword><keyword xml:id="kwd4">Progressive supranuclear palsy</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Dysphagia is common in both Parkinson's disease (PD) and progressive supranuclear palsy (PSP). Although it is believed to be more common in PSP, there are no controlled data and no comparison of swallowing function between these two disorders. Our aim was to assess dysphagia and swallow function in patients with PSP and PD. Seven patients with PSP were matched to seven patients with PD on the basis of disease duration. Self‐rated dysphagia, movement disorder disability, modified barium swallow results, and abnormalities noted on manometry of the lower esophageal sphincter, esophageal body, upper esophageal sphincter, and pharynx were compared between the two groups. Neither severity nor duration of dysphagia differed between the two groups. Patients with PSP had a significantly greater degree of disability [median (range) Hoehn & Yahr score, 4 (3–5) vs. 2 (1–2); p < 0.002]. Manometric abnormalities were similar for the two groups. Oral‐phase abnormalities on modified barium swallow were significantly more frequent in PSP (four patients with PSP vs. no patients with PD; p < 0.005). Pharyngeal abnormalities did not differ. Modified barium‐swallow scores correalated well with self‐reported dysphagia severity for patients with PSP (r = 0.93; p < 0.05) but not for those with PD (r = 0.42; p = NS). The frequency of abnormalities noted during the oral phase was significantly increased in PSP. It is hypothesized that the sensory information conveyed due to this may account for the better correlation between symptoms and swallowing abnormalities and the belief that swallowing problems are more common in PSP.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Comparison of swallowing function in Parkinson's disease and progressive supranuclear palsy</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>SWALLOWING IN PSP AND PARKINSON'S DISEASE</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Comparison of swallowing function in Parkinson's disease and progressive supranuclear palsy</title></titleInfo><name type="personal"><namePart type="termsOfAddress">Dr.</namePart><namePart type="family">Johnston</namePart><affiliation>Departments of Medicine, Graduate Hospital, Philadelphia, Pennsylvania, U.S.A.</affiliation><description>Correspondence: Lagan Valley Hospital, Hillsborough Rd., Lisburn, Co. Antrim, BT281JP, UK</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">June A.</namePart><namePart type="family">Castell</namePart><affiliation>Departments of Medicine, Graduate Hospital, Philadelphia, Pennsylvania, U.S.A.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Sharon</namePart><namePart type="family">Stumacher</namePart><affiliation>Speech/Language Pathology, Department of Neurology, Graduate Hospital, Philadelphia, Pennsylvania, U.S.A.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Amy</namePart><namePart type="family">Colcher</namePart><affiliation>Departments of Medicine, Movement Disorders Clinic, Department of Neurology, Graduate Hospital, Philadelphia, Pennsylvania, U.S.A.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R. Matthew</namePart><namePart type="family">Gideon</namePart><affiliation>Departments of Medicine, Graduate Hospital, Philadelphia, Pennsylvania, U.S.A.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Qun</namePart><namePart type="family">Li</namePart><affiliation>Departments of Medicine, Graduate Hospital, Philadelphia, Pennsylvania, U.S.A.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Donald O.</namePart><namePart type="family">Castell</namePart><affiliation>Departments of Medicine, Graduate Hospital, Philadelphia, Pennsylvania, U.S.A.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">1997-05</dateIssued><dateCaptured encoding="w3cdtf">1995-07-19</dateCaptured><dateValid encoding="w3cdtf">1996-10-30</dateValid><copyrightDate encoding="w3cdtf">1997</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">1</extent><extent unit="tables">4</extent><extent unit="references">26</extent></physicalDescription><abstract lang="en">Dysphagia is common in both Parkinson's disease (PD) and progressive supranuclear palsy (PSP). Although it is believed to be more common in PSP, there are no controlled data and no comparison of swallowing function between these two disorders. Our aim was to assess dysphagia and swallow function in patients with PSP and PD. Seven patients with PSP were matched to seven patients with PD on the basis of disease duration. Self‐rated dysphagia, movement disorder disability, modified barium swallow results, and abnormalities noted on manometry of the lower esophageal sphincter, esophageal body, upper esophageal sphincter, and pharynx were compared between the two groups. Neither severity nor duration of dysphagia differed between the two groups. Patients with PSP had a significantly greater degree of disability [median (range) Hoehn & Yahr score, 4 (3–5) vs. 2 (1–2); p < 0.002]. Manometric abnormalities were similar for the two groups. Oral‐phase abnormalities on modified barium swallow were significantly more frequent in PSP (four patients with PSP vs. no patients with PD; p < 0.005). Pharyngeal abnormalities did not differ. Modified barium‐swallow scores correalated well with self‐reported dysphagia severity for patients with PSP (r = 0.93; p < 0.05) but not for those with PD (r = 0.42; p = NS). The frequency of abnormalities noted during the oral phase was significantly increased in PSP. It is hypothesized that the sensory information conveyed due to this may account for the better correlation between symptoms and swallowing abnormalities and the belief that swallowing problems are more common in PSP.</abstract><subject lang="en"><genre>Keywords</genre><topic>Dysphagia</topic><topic>Modified barium swallow</topic><topic>Parkinson's disease</topic><topic>Progressive supranuclear palsy</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><genre type="Journal">journal</genre><subject><genre>article category</genre><topic>Article</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>1997</date><detail type="volume"><caption>vol.</caption><number>12</number></detail><detail type="issue"><caption>no.</caption><number>3</number></detail><extent unit="pages"><start>322</start><end>327</end><total>6</total></extent></part></relatedItem><identifier type="istex">7CDE05B7FBE4557956BA837F1AE876221D3A2409</identifier><identifier type="DOI">10.1002/mds.870120310</identifier><identifier type="ArticleID">MDS870120310</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 1997 Movement Disorder Society</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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