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Assessment of hallucinations in Parkinson’s disease using a novel scale

Identifieur interne : 001008 ( Main/Corpus ); précédent : 001007; suivant : 001009

Assessment of hallucinations in Parkinson’s disease using a novel scale

Auteurs : K. Wada-Isoe ; K. Ohta ; K. Imamura ; M. Kitayama ; T. Nomura ; K. Yasui ; K. Nakaso ; K. Nakashima

Source :

RBID : ISTEX:F65B7149B64EC0C740AA74242B95CCA502FF44AB

English descriptors

Abstract

Objective –  To assess hallucinations in Parkinson’s disease (PD), we developed a novel practical rating scale that evaluates five items including variety, frequency, and severity of hallucinations, caregiver burden levels, and psychiatric status at nighttime. Methods –  Forty‐one PD patients and their caregivers were examined regarding the status of the hallucinations associated with PD. Results –  As a measure of internal consistency, the Tottori University Hallucination Rating Scale (TUHARS) has a Cronbach’s α of 0.88. Mini‐Mental State Examination (MMSE) and Hoehn–Yahr stage were associated with the TUHARS scores in a multivariate regression analysis. Visual hallucinations are the most common. However, half of the patients who reported visual hallucinations also had other hallucinations. The scale scores in the PD patients with dementia (PDD) group were significantly greater than in the PD patients without dementia (PDnD) group. Conclusions –  TUHARS appears to be a suitable and easily administered instrument for assessment of hallucinations in PD. PD patients experienced various kinds of hallucinations. Hallucinations may have a close relationship with cognitive decline in PD patients.

Url:
DOI: 10.1111/j.1600-0404.2007.00907.x

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ISTEX:F65B7149B64EC0C740AA74242B95CCA502FF44AB

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<correspondenceTo>Kenji Wada‐Isoe, Department of Neurology, Faculty of Medicine, Institute of Neurological Sciences, Tottori University, 36‐1 Nishi‐cho, Yonago 683‐8504, Japan
Tel.: +81 859 38 6757
Fax: +81 859 38 6759
e‐mail:
<email normalForm="kewada@grape.med.tottori-u.ac.jp">kewada@grape.med.tottori‐u.ac.jp</email>
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<unparsedEditorialHistory>Accepted for publication June 26, 2007</unparsedEditorialHistory>
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<count type="figureTotal" number="4"></count>
<count type="tableTotal" number="2"></count>
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<titleGroup>
<title type="main">Assessment of hallucinations in Parkinson’s disease using a novel scale</title>
<title type="shortAuthors">
<b>Wada‐Isoe et al.</b>
</title>
<title type="short">
<b>Assessment of hallucinations in PD</b>
</title>
</titleGroup>
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<creator creatorRole="author" xml:id="cr1" affiliationRef="#aff-1-1">
<personName>
<givenNames>K.</givenNames>
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<familyName>Ohta</familyName>
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<personName>
<givenNames>K.</givenNames>
<familyName>Imamura</familyName>
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<creator creatorRole="author" xml:id="cr4" affiliationRef="#aff-1-1">
<personName>
<givenNames>M.</givenNames>
<familyName>Kitayama</familyName>
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<personName>
<givenNames>T.</givenNames>
<familyName>Nomura</familyName>
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<personName>
<givenNames>K.</givenNames>
<familyName>Yasui</familyName>
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<personName>
<givenNames>K.</givenNames>
<familyName>Nakaso</familyName>
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<personName>
<givenNames>K.</givenNames>
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<unparsedAffiliation>Department of Neurology, Faculty of Medicine, Institute of Neurological Sciences, Tottori University, Yonago, Japan</unparsedAffiliation>
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<keyword xml:id="k1">dementia</keyword>
<keyword xml:id="k2">hallucinations</keyword>
<keyword xml:id="k3">Lewy bodies</keyword>
<keyword xml:id="k4">Parkinson’s disease</keyword>
<keyword xml:id="k5">psychiatric symptoms</keyword>
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<abstract type="main" xml:lang="en"><!-- Wada-Isoe K, Ohta K, Imamura K, Kitayama M, Nomura T, Yasui K, Nakaso K, Nakashima K. Assessment of hallucinations in Parkinson&rsquo;s disease using a novel scale.

Acta Neurol Scand: 2008: 117: 35&ndash;40.

&copy; 2007 The Authors Journal compilation &copy; 2007 Blackwell Munksgaard.
-->
<p>
<b>Objective – </b>
To assess hallucinations in Parkinson’s disease (PD), we developed a novel practical rating scale that evaluates five items including variety, frequency, and severity of hallucinations, caregiver burden levels, and psychiatric status at nighttime.</p>
<p>
<b>Methods – </b>
Forty‐one PD patients and their caregivers were examined regarding the status of the hallucinations associated with PD.</p>
<p>
<b>Results – </b>
As a measure of internal consistency, the Tottori University Hallucination Rating Scale (TUHARS) has a Cronbach’s α of 0.88. Mini‐Mental State Examination (MMSE) and Hoehn–Yahr stage were associated with the TUHARS scores in a multivariate regression analysis. Visual hallucinations are the most common. However, half of the patients who reported visual hallucinations also had other hallucinations. The scale scores in the PD patients with dementia (PDD) group were significantly greater than in the PD patients without dementia (PDnD) group.</p>
<p>
<b>Conclusions – </b>
TUHARS appears to be a suitable and easily administered instrument for assessment of hallucinations in PD. PD patients experienced various kinds of hallucinations. Hallucinations may have a close relationship with cognitive decline in PD patients.</p>
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<abstract lang="en">Objective –  To assess hallucinations in Parkinson’s disease (PD), we developed a novel practical rating scale that evaluates five items including variety, frequency, and severity of hallucinations, caregiver burden levels, and psychiatric status at nighttime. Methods –  Forty‐one PD patients and their caregivers were examined regarding the status of the hallucinations associated with PD. Results –  As a measure of internal consistency, the Tottori University Hallucination Rating Scale (TUHARS) has a Cronbach’s α of 0.88. Mini‐Mental State Examination (MMSE) and Hoehn–Yahr stage were associated with the TUHARS scores in a multivariate regression analysis. Visual hallucinations are the most common. However, half of the patients who reported visual hallucinations also had other hallucinations. The scale scores in the PD patients with dementia (PDD) group were significantly greater than in the PD patients without dementia (PDnD) group. Conclusions –  TUHARS appears to be a suitable and easily administered instrument for assessment of hallucinations in PD. PD patients experienced various kinds of hallucinations. Hallucinations may have a close relationship with cognitive decline in PD patients.</abstract>
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<genre>Keywords</genre>
<topic>dementia</topic>
<topic>hallucinations</topic>
<topic>Lewy bodies</topic>
<topic>Parkinson’s disease</topic>
<topic>psychiatric symptoms</topic>
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