Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease
Identifieur interne : 000D33 ( Main/Corpus ); précédent : 000D32; suivant : 000D34Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease
Auteurs : Ali Samii ; Valerie E. Kelly ; Jefferson C. Slimp ; Anne Shumway-Cook ; Robert GoodkinSource :
- Movement Disorders [ 0885-3185 ] ; 2007-07-30.
English descriptors
Abstract
In 17 consecutive patients with Parkinson disease (PD), bilateral subthalamic nucleus (STN) stimulators were implanted during staged surgeries. The Unified Parkinson Disease Rating Scale (UPDRS) and the Dyskinesia Disability Scale were completed both off and on medication prior to any surgery and also OFF and ON stimulation after each surgery. On‐medication UPDRS activities of daily living (ADL) and motor examination scores changed little with unilateral or bilateral stimulation. Off‐medication UPDRS motor examination scores improved to similar degrees after each staged STN electrode implantation. Most of the improvements in off‐medication ADL scores, dyskinesia scores, complications of therapy, and medication dose reduction occurred after unilateral STN stimulation with smaller improvements after the second operation. © 2007 Movement Disorder Society
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DOI: 10.1002/mds.21554
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ISTEX:A7077B27D2745FBA26B5077F214D5822D3FA30CDLe document en format XML
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The Unified Parkinson Disease Rating Scale (UPDRS) and the Dyskinesia Disability Scale were completed both off and on medication prior to any surgery and also OFF and ON stimulation after each surgery. On‐medication UPDRS activities of daily living (ADL) and motor examination scores changed little with unilateral or bilateral stimulation. Off‐medication UPDRS motor examination scores improved to similar degrees after each staged STN electrode implantation. 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Slimp PhD</name><affiliations><json:string>Department of Rehabilitation Medicine, University of Washington, Seattle, Washington, USA</json:string></affiliations></json:item><json:item><name>Anne Shumway‐Cook PhD</name><affiliations><json:string>Department of Rehabilitation Medicine, University of Washington, Seattle, Washington, USA</json:string></affiliations></json:item><json:item><name>Robert Goodkin MD</name><affiliations><json:string>Department of Neurological Surgery, University of Washington, Seattle, Washington, USA</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Parkinson disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>deep brain stimulation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>staged surgery</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>subthalamic nucleus</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>dyskinesia</value></json:item></subject><articleId><json:string>MDS21554</json:string></articleId><language><json:string>eng</json:string></language><abstract>In 17 consecutive patients with Parkinson disease (PD), bilateral subthalamic nucleus (STN) stimulators were implanted during staged surgeries. 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The Unified Parkinson Disease Rating Scale (UPDRS) and the Dyskinesia Disability Scale were completed both <i>off</i> and <i>on</i> medication prior to any surgery and also OFF and ON stimulation after each surgery. <i>On</i>‐medication UPDRS activities of daily living (ADL) and motor examination scores changed little with unilateral or bilateral stimulation. <i>Off‐</i>medication UPDRS motor examination scores improved to similar degrees after each staged STN electrode implantation. Most of the improvements in <i>off</i>‐medication ADL scores, dyskinesia scores, complications of therapy, and medication dose reduction occurred after unilateral STN stimulation with smaller improvements after the second operation. © 2007 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Staged STN Stimulator Implantation in PD</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease</title></titleInfo><name type="personal"><namePart type="given">Ali</namePart><namePart type="family">Samii</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University of Washington, Seattle, Washington, USA</affiliation><affiliation>Parkinson Disease Research Education and Clinical Center, Neurology Section, VA Puget Sound Health Care System, Seattle, Washington, USA</affiliation><description>Correspondence: Department of Neurology, mailstop 127, 1660 S. Columbian Way, Seattle, Washington 98108</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Valerie E.</namePart><namePart type="family">Kelly</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Rehabilitation Medicine, University of Washington, Seattle, Washington, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jefferson C.</namePart><namePart type="family">Slimp</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Rehabilitation Medicine, University of Washington, Seattle, Washington, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Anne</namePart><namePart type="family">Shumway‐Cook</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Rehabilitation Medicine, University of Washington, Seattle, Washington, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Robert</namePart><namePart type="family">Goodkin</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Surgery, University of Washington, Seattle, Washington, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2007-07-30</dateIssued><dateCaptured encoding="w3cdtf">2006-11-06</dateCaptured><dateValid encoding="w3cdtf">2007-04-04</dateValid><copyrightDate encoding="w3cdtf">2007</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">2</extent><extent unit="tables">1</extent><extent unit="references">13</extent><extent unit="words">3422</extent></physicalDescription><abstract lang="en">In 17 consecutive patients with Parkinson disease (PD), bilateral subthalamic nucleus (STN) stimulators were implanted during staged surgeries. The Unified Parkinson Disease Rating Scale (UPDRS) and the Dyskinesia Disability Scale were completed both off and on medication prior to any surgery and also OFF and ON stimulation after each surgery. On‐medication UPDRS activities of daily living (ADL) and motor examination scores changed little with unilateral or bilateral stimulation. Off‐medication UPDRS motor examination scores improved to similar degrees after each staged STN electrode implantation. Most of the improvements in off‐medication ADL scores, dyskinesia scores, complications of therapy, and medication dose reduction occurred after unilateral STN stimulation with smaller improvements after the second operation. © 2007 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>Parkinson disease</topic><topic>deep brain stimulation</topic><topic>staged surgery</topic><topic>subthalamic nucleus</topic><topic>dyskinesia</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. 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|area= ParkinsonV1
|flux= Main
|étape= Corpus
|type= RBID
|clé= ISTEX:A7077B27D2745FBA26B5077F214D5822D3FA30CD
|texte= Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease
}}
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