SCOPA‐cognition cutoff value for detection of Parkinson's disease dementia
Identifieur interne : 000527 ( Main/Corpus ); précédent : 000526; suivant : 000528SCOPA‐cognition cutoff value for detection of Parkinson's disease dementia
Auteurs : Dagmar Verbaan ; Martine Jeukens-Visser ; Teus Van Laar ; Stephanie M. Van Rooden ; Erik W. Van Zwet ; Johan Marinus ; Jacobus J. Van HiltenSource :
- Movement Disorders [ 0885-3185 ] ; 2011-08-15.
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- KwdEn :
Abstract
The SCOPA‐Cognition is a reliable and valid test to evaluate cognitive functioning in Parkinson's disease and is widely used in clinical and research settings. Recently, the Movement Disorder Society introduced criteria for Parkinson's disease dementia. The objective of the present study was to use these criteria to determine SCOPA‐Cognition cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. A total of 282 patients with Parkinson's disease were assessed with the SCOPA‐Cognition and the Movement Disorder Society's Parkinson's disease dementia criteria. From the 275 patients with a complete assessment of the dementia criteria, 12% (n = 32) fulfilled the criteria. Data from 268 patients with complete assessments of both the dementia criteria and the SCOPA‐Cognition were used to determine cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. The area under the curve was 0.91 (95% confidence interval, 0.85–0.97), showing a strong association between the dementia criteria and the SCOPA‐Cognition. The cutoff for maximum accuracy was 22/23, based on the highest sum of sensitivity (0.80) and specificity (0.87), with positive and negative predictive values of 0.43 and 0.97, respectively. The optimal screening cutoff was 24/25, and the optimal diagnostic cutoff was 17/18. Using the recently published Parkinson's disease dementia criteria as a reference, the current study presents SCOPA‐Cognition cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. The availability of SCOPA‐Cognition cutoffs for Parkinson's disease dementia may contribute to the scale's usefulness and promote its further use in both clinical and research settings. © 2011 Movement Disorder Society
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DOI: 10.1002/mds.23750
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Van Hilten</name><affiliation><mods:affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. 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Recently, the Movement Disorder Society introduced criteria for Parkinson's disease dementia. The objective of the present study was to use these criteria to determine SCOPA‐Cognition cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. A total of 282 patients with Parkinson's disease were assessed with the SCOPA‐Cognition and the Movement Disorder Society's Parkinson's disease dementia criteria. From the 275 patients with a complete assessment of the dementia criteria, 12% (n = 32) fulfilled the criteria. Data from 268 patients with complete assessments of both the dementia criteria and the SCOPA‐Cognition were used to determine cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. The area under the curve was 0.91 (95% confidence interval, 0.85–0.97), showing a strong association between the dementia criteria and the SCOPA‐Cognition. The cutoff for maximum accuracy was 22/23, based on the highest sum of sensitivity (0.80) and specificity (0.87), with positive and negative predictive values of 0.43 and 0.97, respectively. The optimal screening cutoff was 24/25, and the optimal diagnostic cutoff was 17/18. Using the recently published Parkinson's disease dementia criteria as a reference, the current study presents SCOPA‐Cognition cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. The availability of SCOPA‐Cognition cutoffs for Parkinson's disease dementia may contribute to the scale's usefulness and promote its further use in both clinical and research settings. © 2011 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Dagmar Verbaan PhD</name><affiliations><json:string>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</json:string></affiliations></json:item><json:item><name>Martine Jeukens‐Visser PhD</name><affiliations><json:string>Department of Rehabilitation, Academic Medical Center, Amsterdam, The Netherlands</json:string></affiliations></json:item><json:item><name>Teus Van Laar MD, PhD</name><affiliations><json:string>Department of Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</json:string></affiliations></json:item><json:item><name>Stephanie M. van Rooden MSc</name><affiliations><json:string>Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands</json:string></affiliations></json:item><json:item><name>Erik W. Van Zwet PhD</name><affiliations><json:string>Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands</json:string></affiliations></json:item><json:item><name>Johan Marinus PhD</name><affiliations><json:string>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</json:string></affiliations></json:item><json:item><name>Jacobus J. van Hilten MD, PhD</name><affiliations><json:string>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease dementia</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>cutoff value</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>SCOPA‐Cognition</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Movement Disorder Society Parkinson's disease dementia criteria</value></json:item></subject><articleId><json:string>MDS23750</json:string></articleId><language><json:string>eng</json:string></language><abstract>The SCOPA‐Cognition is a reliable and valid test to evaluate cognitive functioning in Parkinson's disease and is widely used in clinical and research settings. Recently, the Movement Disorder Society introduced criteria for Parkinson's disease dementia. The objective of the present study was to use these criteria to determine SCOPA‐Cognition cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. A total of 282 patients with Parkinson's disease were assessed with the SCOPA‐Cognition and the Movement Disorder Society's Parkinson's disease dementia criteria. From the 275 patients with a complete assessment of the dementia criteria, 12% (n = 32) fulfilled the criteria. Data from 268 patients with complete assessments of both the dementia criteria and the SCOPA‐Cognition were used to determine cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. The area under the curve was 0.91 (95% confidence interval, 0.85–0.97), showing a strong association between the dementia criteria and the SCOPA‐Cognition. The cutoff for maximum accuracy was 22/23, based on the highest sum of sensitivity (0.80) and specificity (0.87), with positive and negative predictive values of 0.43 and 0.97, respectively. The optimal screening cutoff was 24/25, and the optimal diagnostic cutoff was 17/18. Using the recently published Parkinson's disease dementia criteria as a reference, the current study presents SCOPA‐Cognition cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. The availability of SCOPA‐Cognition cutoffs for Parkinson's disease dementia may contribute to the scale's usefulness and promote its further use in both clinical and research settings. © 2011 Movement Disorder Society</abstract><qualityIndicators><score>6.733</score><pdfVersion>1.3</pdfVersion><pdfPageSize>612 x 810 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>4</keywordCount><abstractCharCount>1788</abstractCharCount><pdfWordCount>3733</pdfWordCount><pdfCharCount>24406</pdfCharCount><pdfPageCount>6</pdfPageCount><abstractWordCount>253</abstractWordCount></qualityIndicators><title>SCOPA‐cognition cutoff value for detection of Parkinson's disease dementia</title><genre><json:string>article</json:string></genre><host><volume>26</volume><publisherId><json:string>MDS</json:string></publisherId><pages><total>6</total><last>1886</last><first>1881</first></pages><issn><json:string>0885-3185</json:string></issn><issue>10</issue><subject><json:item><value>Research Article</value></json:item></subject><genre><json:string>Journal</json:string></genre><language><json:string>unknown</json:string></language><eissn><json:string>1531-8257</json:string></eissn><title>Movement Disorders</title><doi><json:string>10.1002/(ISSN)1531-8257</json:string></doi></host><publicationDate>2011</publicationDate><copyrightDate>2011</copyrightDate><doi><json:string>10.1002/mds.23750</json:string></doi><id>B4A3CCE19B6C047FF90E3A0041F65DD5335474E9</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/B4A3CCE19B6C047FF90E3A0041F65DD5335474E9/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/B4A3CCE19B6C047FF90E3A0041F65DD5335474E9/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/B4A3CCE19B6C047FF90E3A0041F65DD5335474E9/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">SCOPA‐cognition cutoff value for detection of Parkinson's disease dementia</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><availability><p>WILEY</p></availability><date>2011</date></publicationStmt><notesStmt><note type="content">*Funding agencies: This work was supported by grants from Novartis, the Prinses Beatrix Fonds (PBF, project no. WAR05‐0120), the van Alkemade‐Keuls Foundation, and the Dutch Parkinson's Disease Society.</note><note type="content">*Relevant conflicts of interest/financial disclosures: Nothing to report.</note><note type="content">*Full financial disclosures and author roles may be found in the online version of this article.</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">SCOPA‐cognition cutoff value for detection of Parkinson's disease dementia</title><author><persName><forename type="first">Dagmar</forename><surname>Verbaan</surname></persName><roleName type="degree">PhD</roleName><note type="correspondence"><p>Correspondence: Department of Neurology, K5Q‐92, Leiden University Medical Center, P.O. Box 9600, NL‐2300 RC Leiden, The Netherlands</p></note><affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</affiliation></author><author><persName><forename type="first">Martine</forename><surname>Jeukens‐Visser</surname></persName><roleName type="degree">PhD</roleName><affiliation>Department of Rehabilitation, Academic Medical Center, Amsterdam, The Netherlands</affiliation></author><author><persName><forename type="first">Teus</forename><surname>Van Laar</surname></persName><roleName type="degree">MD, PhD</roleName><affiliation>Department of Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</affiliation></author><author><persName><forename type="first">Stephanie M.</forename><surname>van Rooden</surname></persName><roleName type="degree">MSc</roleName><affiliation>Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands</affiliation></author><author><persName><forename type="first">Erik W.</forename><surname>Van Zwet</surname></persName><roleName type="degree">PhD</roleName><affiliation>Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands</affiliation></author><author><persName><forename type="first">Johan</forename><surname>Marinus</surname></persName><roleName type="degree">PhD</roleName><affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</affiliation></author><author><persName><forename type="first">Jacobus J.</forename><surname>van Hilten</surname></persName><roleName type="degree">MD, PhD</roleName><affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</affiliation></author></analytic><monogr><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="pISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><idno type="DOI">10.1002/(ISSN)1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2011-08-15"></date><biblScope unit="volume">26</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="1881">1881</biblScope><biblScope unit="page" to="1886">1886</biblScope></imprint></monogr><idno type="istex">B4A3CCE19B6C047FF90E3A0041F65DD5335474E9</idno><idno type="DOI">10.1002/mds.23750</idno><idno type="ArticleID">MDS23750</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2011</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>The SCOPA‐Cognition is a reliable and valid test to evaluate cognitive functioning in Parkinson's disease and is widely used in clinical and research settings. Recently, the Movement Disorder Society introduced criteria for Parkinson's disease dementia. The objective of the present study was to use these criteria to determine SCOPA‐Cognition cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. A total of 282 patients with Parkinson's disease were assessed with the SCOPA‐Cognition and the Movement Disorder Society's Parkinson's disease dementia criteria. From the 275 patients with a complete assessment of the dementia criteria, 12% (n = 32) fulfilled the criteria. Data from 268 patients with complete assessments of both the dementia criteria and the SCOPA‐Cognition were used to determine cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. The area under the curve was 0.91 (95% confidence interval, 0.85–0.97), showing a strong association between the dementia criteria and the SCOPA‐Cognition. The cutoff for maximum accuracy was 22/23, based on the highest sum of sensitivity (0.80) and specificity (0.87), with positive and negative predictive values of 0.43 and 0.97, respectively. The optimal screening cutoff was 24/25, and the optimal diagnostic cutoff was 17/18. Using the recently published Parkinson's disease dementia criteria as a reference, the current study presents SCOPA‐Cognition cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. 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Disord.</title></titleGroup></publicationMeta><publicationMeta level="part" position="100"><doi origin="wiley" registered="yes">10.1002/mds.v26.10</doi><numberingGroup><numbering type="journalVolume" number="26">26</numbering><numbering type="journalIssue">10</numbering></numberingGroup><coverDate startDate="2011-08-15">15 August 2011</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="190" status="forIssue"><doi origin="wiley" registered="yes">10.1002/mds.23750</doi><idGroup><id type="unit" value="MDS23750"></id></idGroup><countGroup><count type="pageTotal" number="6"></count></countGroup><titleGroup><title type="articleCategory">Research Article</title><title type="tocHeading1">Research Articles</title></titleGroup><copyright ownership="thirdParty">Copyright © 2011 Movement Disorder Society</copyright><eventGroup><event type="manuscriptReceived" date="2010-11-04"></event><event type="manuscriptRevised" date="2011-03-14"></event><event type="manuscriptAccepted" date="2011-03-15"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:3.0.1 mode:FullText" date="2011-12-15"></event><event type="publishedOnlineEarlyUnpaginated" date="2011-05-03"></event><event type="publishedOnlineFinalForm" date="2011-08-26"></event><event type="firstOnline" date="2011-05-03"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-02-02"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-31"></event></eventGroup><numberingGroup><numbering type="pageFirst">1881</numbering><numbering type="pageLast">1886</numbering></numberingGroup><correspondenceTo>Department of Neurology, K5Q‐92, Leiden University Medical Center, P.O. Box 9600, NL‐2300 RC Leiden, The Netherlands</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:MDS.MDS23750.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="1"></count><count type="tableTotal" number="3"></count><count type="referenceTotal" number="31"></count><count type="wordTotal" number="5231"></count></countGroup><titleGroup><title type="main" xml:lang="en">SCOPA‐cognition cutoff value for detection of Parkinson's disease dementia<link href="#fn1"></link><link href="#fn2"></link><link href="#fn3"></link></title><title type="short" xml:lang="en">SCOPA‐Cog Cutoff for PDD</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Dagmar</givenNames><familyName>Verbaan</familyName><degrees>PhD</degrees></personName><contactDetails><email>D.Verbaan@lumc.nl</email></contactDetails></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Martine</givenNames><familyName>Jeukens‐Visser</familyName><degrees>PhD</degrees></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af3"><personName><givenNames>Teus</givenNames><familyName>Van Laar</familyName><degrees>MD, PhD</degrees></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af4"><personName><givenNames>Stephanie M.</givenNames><familyName>van Rooden</familyName><degrees>MSc</degrees></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af5"><personName><givenNames>Erik W.</givenNames><familyName>Van Zwet</familyName><degrees>PhD</degrees></personName></creator><creator xml:id="au6" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Johan</givenNames><familyName>Marinus</familyName><degrees>PhD</degrees></personName></creator><creator xml:id="au7" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Jacobus J.</givenNames><familyName>van Hilten</familyName><degrees>MD, PhD</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="NL" type="organization"><unparsedAffiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="NL" type="organization"><unparsedAffiliation>Department of Rehabilitation, Academic Medical Center, Amsterdam, The Netherlands</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="NL" type="organization"><unparsedAffiliation>Department of Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</unparsedAffiliation></affiliation><affiliation xml:id="af4" countryCode="NL" type="organization"><unparsedAffiliation>Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands</unparsedAffiliation></affiliation><affiliation xml:id="af5" countryCode="NL" type="organization"><unparsedAffiliation>Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">Parkinson's disease dementia</keyword><keyword xml:id="kwd2">cutoff value</keyword><keyword xml:id="kwd3">SCOPA‐Cognition</keyword><keyword xml:id="kwd4"><i>Movement</i> Disorder Society Parkinson's disease dementia criteria</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>The SCOPA‐Cognition is a reliable and valid test to evaluate cognitive functioning in Parkinson's disease and is widely used in clinical and research settings. Recently, the <i>Movement</i> Disorder Society introduced criteria for Parkinson's disease dementia. The objective of the present study was to use these criteria to determine SCOPA‐Cognition cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. A total of 282 patients with Parkinson's disease were assessed with the SCOPA‐Cognition and the <i>Movement</i> Disorder Society's Parkinson's disease dementia criteria. From the 275 patients with a complete assessment of the dementia criteria, 12% (n = 32) fulfilled the criteria. Data from 268 patients with complete assessments of both the dementia criteria and the SCOPA‐Cognition were used to determine cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. The area under the curve was 0.91 (95% confidence interval, 0.85–0.97), showing a strong association between the dementia criteria and the SCOPA‐Cognition. The cutoff for maximum accuracy was 22/23, based on the highest sum of sensitivity (0.80) and specificity (0.87), with positive and negative predictive values of 0.43 and 0.97, respectively. The optimal screening cutoff was 24/25, and the optimal diagnostic cutoff was 17/18. Using the recently published Parkinson's disease dementia criteria as a reference, the current study presents SCOPA‐Cognition cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. The availability of SCOPA‐Cognition cutoffs for Parkinson's disease dementia may contribute to the scale's usefulness and promote its further use in both clinical and research settings. © 2011 Movement Disorder Society</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="fn1"><p><b>Funding agencies:</b> This work was supported by grants from Novartis, the Prinses Beatrix Fonds (PBF, project no. WAR05‐0120), the van Alkemade‐Keuls Foundation, and the Dutch Parkinson's Disease Society.</p></note><note xml:id="fn2"><p><b>Relevant conflicts of interest/financial disclosures:</b> Nothing to report.</p></note><note xml:id="fn3"><p>Full financial disclosures and author roles may be found in the online version of this article.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>SCOPA‐cognition cutoff value for detection of Parkinson's disease dementia</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>SCOPA‐Cog Cutoff for PDD</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>SCOPA‐cognition cutoff value for detection of Parkinson's disease dementia</title></titleInfo><name type="personal"><namePart type="given">Dagmar</namePart><namePart type="family">Verbaan</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</affiliation><description>Correspondence: Department of Neurology, K5Q‐92, Leiden University Medical Center, P.O. Box 9600, NL‐2300 RC Leiden, The Netherlands</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Martine</namePart><namePart type="family">Jeukens‐Visser</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Rehabilitation, Academic Medical Center, Amsterdam, The Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Teus</namePart><namePart type="family">Van Laar</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department of Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Stephanie M.</namePart><namePart type="family">van Rooden</namePart><namePart type="termsOfAddress">MSc</namePart><affiliation>Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Erik W.</namePart><namePart type="family">Van Zwet</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Johan</namePart><namePart type="family">Marinus</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jacobus J.</namePart><namePart type="family">van Hilten</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2011-08-15</dateIssued><dateCaptured encoding="w3cdtf">2010-11-04</dateCaptured><dateValid encoding="w3cdtf">2011-03-15</dateValid><copyrightDate encoding="w3cdtf">2011</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">1</extent><extent unit="tables">3</extent><extent unit="references">31</extent><extent unit="words">5231</extent></physicalDescription><abstract lang="en">The SCOPA‐Cognition is a reliable and valid test to evaluate cognitive functioning in Parkinson's disease and is widely used in clinical and research settings. Recently, the Movement Disorder Society introduced criteria for Parkinson's disease dementia. The objective of the present study was to use these criteria to determine SCOPA‐Cognition cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. A total of 282 patients with Parkinson's disease were assessed with the SCOPA‐Cognition and the Movement Disorder Society's Parkinson's disease dementia criteria. From the 275 patients with a complete assessment of the dementia criteria, 12% (n = 32) fulfilled the criteria. Data from 268 patients with complete assessments of both the dementia criteria and the SCOPA‐Cognition were used to determine cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. The area under the curve was 0.91 (95% confidence interval, 0.85–0.97), showing a strong association between the dementia criteria and the SCOPA‐Cognition. The cutoff for maximum accuracy was 22/23, based on the highest sum of sensitivity (0.80) and specificity (0.87), with positive and negative predictive values of 0.43 and 0.97, respectively. The optimal screening cutoff was 24/25, and the optimal diagnostic cutoff was 17/18. Using the recently published Parkinson's disease dementia criteria as a reference, the current study presents SCOPA‐Cognition cutoffs for maximum accuracy, screening, and diagnosing of Parkinson's disease dementia. The availability of SCOPA‐Cognition cutoffs for Parkinson's disease dementia may contribute to the scale's usefulness and promote its further use in both clinical and research settings. © 2011 Movement Disorder Society</abstract><note type="content">*Funding agencies: This work was supported by grants from Novartis, the Prinses Beatrix Fonds (PBF, project no. WAR05‐0120), the van Alkemade‐Keuls Foundation, and the Dutch Parkinson's Disease Society.</note><note type="content">*Relevant conflicts of interest/financial disclosures: Nothing to report.</note><note type="content">*Full financial disclosures and author roles may be found in the online version of this article.</note><subject lang="en"><genre>Keywords</genre><topic>Parkinson's disease dementia</topic><topic>cutoff value</topic><topic>SCOPA‐Cognition</topic><topic>Movement Disorder Society Parkinson's disease dementia criteria</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><genre type="Journal">journal</genre><subject><genre>article category</genre><topic>Research Article</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>26</number></detail><detail type="issue"><caption>no.</caption><number>10</number></detail><extent unit="pages"><start>1881</start><end>1886</end><total>6</total></extent></part></relatedItem><identifier type="istex">B4A3CCE19B6C047FF90E3A0041F65DD5335474E9</identifier><identifier type="DOI">10.1002/mds.23750</identifier><identifier type="ArticleID">MDS23750</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2011 Movement Disorder Society</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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