Electroconvulsive therapy in the treatment of neuropsychiatric conditions and transcranial magnetic stimulation as a pathophysiological probe in neuropsychiatry
Identifieur interne : 000349 ( Main/Corpus ); précédent : 000348; suivant : 000350Electroconvulsive therapy in the treatment of neuropsychiatric conditions and transcranial magnetic stimulation as a pathophysiological probe in neuropsychiatry
Auteurs : William M. Mcdonald ; Benjamin D. GreenbergSource :
- Depression and Anxiety [ 1091-4269 ] ; 2000.
English descriptors
- KwdEn :
Abstract
It is a challenging task to review transcranial magnetic stimulation (TMS) studies in neuropsychiatric disorders alongside assessments of longstanding clinical applications of ECT as an empirical treatment. The task is challenging because TMS was developed as a probe of neural mechanisms, whereas, in marked contrast, ECT has been a clinical technique from its inception. Since the onset of modern psychopharmacology, the understanding of the potential applications of ECT to neuropsychiatric disorders is generally restricted to case reports of patients with intractable disease that have had at least a partial response to ECT. Studies of the possible efficacy of TMS in neuropsychiatric conditions have a significant advantage over ECT as the treatments are associated with less morbidity. The only serious known complication in TMS is a risk of seizures that may increase in patients with neuropsychiatric conditions such as course brain disease. Only cortical structures are themselves accessible to TMS using current technology. Present TMS techniques, however, seem capable of affecting activity in deeper brain structures that are functionally linked to cortical brain regions. TMS permits novel explorations of relationships between regional brain activity and symptoms of a number of neuropsychiatric disorders, as well as in research relating activity in functionally related brain regions to modulation of cognition and affective states in healthy individuals. This is particularly true at present because TMS and powerful neuroimaging and neuropsychological tools are all making rapid advances simultaneously. Depression and Anxiety 12:135–143, 2000. © 2000 Wiley‐Liss, Inc.
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DOI: 10.1002/1520-6394(2000)12:3<135::AID-DA5>3.0.CO;2-4
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The task is challenging because TMS was developed as a probe of neural mechanisms, whereas, in marked contrast, ECT has been a clinical technique from its inception. Since the onset of modern psychopharmacology, the understanding of the potential applications of ECT to neuropsychiatric disorders is generally restricted to case reports of patients with intractable disease that have had at least a partial response to ECT. Studies of the possible efficacy of TMS in neuropsychiatric conditions have a significant advantage over ECT as the treatments are associated with less morbidity. The only serious known complication in TMS is a risk of seizures that may increase in patients with neuropsychiatric conditions such as course brain disease. Only cortical structures are themselves accessible to TMS using current technology. Present TMS techniques, however, seem capable of affecting activity in deeper brain structures that are functionally linked to cortical brain regions. TMS permits novel explorations of relationships between regional brain activity and symptoms of a number of neuropsychiatric disorders, as well as in research relating activity in functionally related brain regions to modulation of cognition and affective states in healthy individuals. This is particularly true at present because TMS and powerful neuroimaging and neuropsychological tools are all making rapid advances simultaneously. Depression and Anxiety 12:135–143, 2000. © 2000 Wiley‐Liss, Inc.</abstract><subject lang="en"><genre>Keywords</genre><topic>electroconvulsive therapy</topic><topic>transcranial magnetic stimulation</topic><topic>neuropsychiatry</topic><topic>neuropsychiatric disorders</topic><topic>neurological disorders</topic><topic>obsessive compulsive disorders</topic></subject><relatedItem type="host"><titleInfo><title>Depression and Anxiety</title></titleInfo><titleInfo type="abbreviated"><title>Depress. Anxiety</title></titleInfo><name type="personal"><namePart type="given">Martin P.</namePart><namePart type="family">Szuba</namePart><namePart type="termsOfAddress">M.D.</namePart><affiliation>Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania</affiliation></name><name type="personal"><namePart type="given">Catherine J.</namePart><namePart type="family">Datto</namePart><namePart type="termsOfAddress">M.D.</namePart><affiliation>University of Pennsylvania, Philadelphia, Pennsylvania</affiliation></name><name type="personal"><namePart type="given">Sarah H.</namePart><namePart type="family">Lisanby</namePart><namePart type="termsOfAddress">M.D.</namePart><affiliation>Department of Biological Psychiatry, New York State Psychiatric Institute and the Departmentof Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York</affiliation></name><genre type="Journal">journal</genre><subject><genre>article category</genre><topic>Research Article</topic></subject><identifier type="ISSN">1091-4269</identifier><identifier type="eISSN">1520-6394</identifier><identifier type="DOI">10.1002/(ISSN)1520-6394</identifier><identifier type="PublisherID">DA</identifier><part><date>2000</date><detail type="title"><title>Electroconvulsive Therapy and Transcranial Magnetic Stimulation</title></detail><detail type="volume"><caption>vol.</caption><number>12</number></detail><detail type="issue"><caption>no.</caption><number>3</number></detail><extent unit="pages"><start>135</start><end>143</end><total>9</total></extent></part></relatedItem><relatedItem type="preceding"><titleInfo><title>DepressionAnxiety</title></titleInfo><identifier type="ISSN">1062-6417</identifier><identifier type="ISSN">1522-7162</identifier><identifier type="ISSN">1070-9797</identifier><identifier type="ISSN">1522-7154</identifier><part><date point="end">1996</date><detail type="volume"><caption>last vol.</caption><number>4</number></detail><detail type="issue"><caption>last no.</caption><number>2</number></detail></part></relatedItem><identifier type="istex">8AFFA7DF9D5DF2DA4BCA5F855903D123D0AA9453</identifier><identifier type="DOI">10.1002/1520-6394(2000)12:3<135::AID-DA5>3.0.CO;2-4</identifier><identifier type="ArticleID">DA5</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2000 Wiley‐Liss, Inc.</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>John Wiley & Sons, Inc.</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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