Relationship between QRS duration and repolarization abnormalities in patients with wolff-parkinson-white syndrome
Identifieur interne : 000298 ( Main/Corpus ); précédent : 000297; suivant : 000299Relationship between QRS duration and repolarization abnormalities in patients with wolff-parkinson-white syndrome
Auteurs : Fumi Inaba-Sato ; Makoto Hirai ; Hiroshi Hayashi ; Yukihiko Yoshida ; Tetsuo Yanagawa ; Yasushi Tomita ; Kazuki Iwata ; Kazunari Abe ; Masayuki Terazawa ; Makoto Akahoshi ; Mikio Sugino ; Hidehiko SaitoSource :
- Journal of Electrocardiology [ 0022-0736 ] ; 1996.
English descriptors
- KwdEn :
Abstract
Marked T wave abnormalities in 12-lead electrocardiograms often appear after radiofrequency ablation in patients with Wolff-Parkinson-White (WPW) syndrome. Durations of the QRS complex before ablation have been reported to be significantly greater in patients with repolarization abnormalities after ablation than in those with normal repolarization. However, there has been no report concerning the relationship between QRS duration and repolarization abnormalities before ablation. It has been reported that QRST isointegral maps are dependent on local cellular repolarization properties but largely independent of activation sequence, and that they provide quantitative information about repolarization abnormalities. Isointegral maps were constructed from data recorded in 34 patients with WPW syndrome and QRS durations of 0.1 second or longer (21 patients with left-sided accessory pathways and 13 with right-sided pathways) in order to investigate the relationship between QRS duration and abnormalities in repolarization properties during preexcitation. Body surface ECGs were recorded with an 87-lead system at a sampling interval of 1 ms. The QRST values (mean ± 2SD) from 607 normal individuals were taken to represent the normal range. The area with abnormally low QRST values was designated as the −2SD area and the sum of the QRST values (ΣQRST) in this area was calculated. The QRS duration was found to be significantly related to ΣQRST. These results demonstrate that the patients with WPW syndrome had abnormalities in local repolarization properties that were significantly related to QRS duration during preexcitation. The degree of preexcitation may be important in producing these abnormalities in patients with manifest WPW syndrome. This may result in T wave abnormalities after ablation of the accessory pathway attributable to cardiac memory.
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DOI: 10.1016/S0022-0736(96)80094-X
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<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Relationship between QRS duration and repolarization abnormalities in patients with wolff-parkinson-white syndrome</title><author><name sortKey="Inaba Sato, Fumi" sort="Inaba Sato, Fumi" uniqKey="Inaba Sato F" first="Fumi" last="Inaba-Sato">Fumi Inaba-Sato</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Hirai, Makoto" sort="Hirai, Makoto" uniqKey="Hirai M" first="Makoto" last="Hirai">Makoto Hirai</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Hayashi, Hiroshi" sort="Hayashi, Hiroshi" uniqKey="Hayashi H" first="Hiroshi" last="Hayashi">Hiroshi Hayashi</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Yoshida, Yukihiko" sort="Yoshida, Yukihiko" uniqKey="Yoshida Y" first="Yukihiko" last="Yoshida">Yukihiko Yoshida</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Yanagawa, Tetsuo" sort="Yanagawa, Tetsuo" uniqKey="Yanagawa T" first="Tetsuo" last="Yanagawa">Tetsuo Yanagawa</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Tomita, Yasushi" sort="Tomita, Yasushi" uniqKey="Tomita Y" first="Yasushi" last="Tomita">Yasushi Tomita</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Iwata, Kazuki" sort="Iwata, Kazuki" uniqKey="Iwata K" first="Kazuki" last="Iwata">Kazuki Iwata</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Abe, Kazunari" sort="Abe, Kazunari" uniqKey="Abe K" first="Kazunari" last="Abe">Kazunari Abe</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Terazawa, Masayuki" sort="Terazawa, Masayuki" uniqKey="Terazawa M" first="Masayuki" last="Terazawa">Masayuki Terazawa</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Akahoshi, Makoto" sort="Akahoshi, Makoto" uniqKey="Akahoshi M" first="Makoto" last="Akahoshi">Makoto Akahoshi</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Sugino, Mikio" sort="Sugino, Mikio" uniqKey="Sugino M" first="Mikio" last="Sugino">Mikio Sugino</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Saito, Hidehiko" sort="Saito, Hidehiko" uniqKey="Saito H" first="Hidehiko" last="Saito">Hidehiko Saito</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:B3595E6F7C7BED01507A2CD42E0883156F3154B9</idno><date when="1996" year="1996">1996</date><idno type="doi">10.1016/S0022-0736(96)80094-X</idno><idno type="url">https://api.istex.fr/document/B3595E6F7C7BED01507A2CD42E0883156F3154B9/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">000298</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Relationship between QRS duration and repolarization abnormalities in patients with wolff-parkinson-white syndrome</title><author><name sortKey="Inaba Sato, Fumi" sort="Inaba Sato, Fumi" uniqKey="Inaba Sato F" first="Fumi" last="Inaba-Sato">Fumi Inaba-Sato</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Hirai, Makoto" sort="Hirai, Makoto" uniqKey="Hirai M" first="Makoto" last="Hirai">Makoto Hirai</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Hayashi, Hiroshi" sort="Hayashi, Hiroshi" uniqKey="Hayashi H" first="Hiroshi" last="Hayashi">Hiroshi Hayashi</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Yoshida, Yukihiko" sort="Yoshida, Yukihiko" uniqKey="Yoshida Y" first="Yukihiko" last="Yoshida">Yukihiko Yoshida</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Yanagawa, Tetsuo" sort="Yanagawa, Tetsuo" uniqKey="Yanagawa T" first="Tetsuo" last="Yanagawa">Tetsuo Yanagawa</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Tomita, Yasushi" sort="Tomita, Yasushi" uniqKey="Tomita Y" first="Yasushi" last="Tomita">Yasushi Tomita</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Iwata, Kazuki" sort="Iwata, Kazuki" uniqKey="Iwata K" first="Kazuki" last="Iwata">Kazuki Iwata</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Abe, Kazunari" sort="Abe, Kazunari" uniqKey="Abe K" first="Kazunari" last="Abe">Kazunari Abe</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Terazawa, Masayuki" sort="Terazawa, Masayuki" uniqKey="Terazawa M" first="Masayuki" last="Terazawa">Masayuki Terazawa</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Akahoshi, Makoto" sort="Akahoshi, Makoto" uniqKey="Akahoshi M" first="Makoto" last="Akahoshi">Makoto Akahoshi</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Sugino, Mikio" sort="Sugino, Mikio" uniqKey="Sugino M" first="Mikio" last="Sugino">Mikio Sugino</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Saito, Hidehiko" sort="Saito, Hidehiko" uniqKey="Saito H" first="Hidehiko" last="Saito">Hidehiko Saito</name><affiliation><mods:affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Electrocardiology</title><title level="j" type="abbrev">YJELC</title><idno type="ISSN">0022-0736</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1996">1996</date><biblScope unit="volume">29</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="301">301</biblScope><biblScope unit="page" to="308">308</biblScope></imprint><idno type="ISSN">0022-0736</idno></series><idno type="istex">B3595E6F7C7BED01507A2CD42E0883156F3154B9</idno><idno type="DOI">10.1016/S0022-0736(96)80094-X</idno><idno type="PII">S0022-0736(96)80094-X</idno><idno type="ArticleID">9680094X</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0022-0736</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>QRST value</term><term>Wolff-Parkinson-White syndrome</term><term>cardiac memory</term><term>isointegral maps</term><term>repolarization</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Marked T wave abnormalities in 12-lead electrocardiograms often appear after radiofrequency ablation in patients with Wolff-Parkinson-White (WPW) syndrome. Durations of the QRS complex before ablation have been reported to be significantly greater in patients with repolarization abnormalities after ablation than in those with normal repolarization. However, there has been no report concerning the relationship between QRS duration and repolarization abnormalities before ablation. It has been reported that QRST isointegral maps are dependent on local cellular repolarization properties but largely independent of activation sequence, and that they provide quantitative information about repolarization abnormalities. Isointegral maps were constructed from data recorded in 34 patients with WPW syndrome and QRS durations of 0.1 second or longer (21 patients with left-sided accessory pathways and 13 with right-sided pathways) in order to investigate the relationship between QRS duration and abnormalities in repolarization properties during preexcitation. Body surface ECGs were recorded with an 87-lead system at a sampling interval of 1 ms. The QRST values (mean ± 2SD) from 607 normal individuals were taken to represent the normal range. The area with abnormally low QRST values was designated as the −2SD area and the sum of the QRST values (ΣQRST) in this area was calculated. The QRS duration was found to be significantly related to ΣQRST. These results demonstrate that the patients with WPW syndrome had abnormalities in local repolarization properties that were significantly related to QRS duration during preexcitation. The degree of preexcitation may be important in producing these abnormalities in patients with manifest WPW syndrome. This may result in T wave abnormalities after ablation of the accessory pathway attributable to cardiac memory.</div></front></TEI><istex><corpusName>elsevier</corpusName><author><json:item><name>Fumi Inaba-Sato MD</name><affiliations><json:string>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</json:string></affiliations></json:item><json:item><name>Makoto Hirai MD</name><affiliations><json:string>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</json:string></affiliations></json:item><json:item><name>Hiroshi Hayashi MD</name><affiliations><json:string>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</json:string></affiliations></json:item><json:item><name>Yukihiko Yoshida MD</name><affiliations><json:string>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</json:string></affiliations></json:item><json:item><name>Tetsuo Yanagawa MD</name><affiliations><json:string>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</json:string></affiliations></json:item><json:item><name>Yasushi Tomita MD</name><affiliations><json:string>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</json:string></affiliations></json:item><json:item><name>Kazuki Iwata MD</name><affiliations><json:string>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</json:string></affiliations></json:item><json:item><name>Kazunari Abe MD</name><affiliations><json:string>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</json:string></affiliations></json:item><json:item><name>Masayuki Terazawa MD</name><affiliations><json:string>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</json:string></affiliations></json:item><json:item><name>Makoto Akahoshi MD</name><affiliations><json:string>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</json:string></affiliations></json:item><json:item><name>Mikio Sugino MD</name><affiliations><json:string>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</json:string></affiliations></json:item><json:item><name>Hidehiko Saito MD</name><affiliations><json:string>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>QRST value</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Wolff-Parkinson-White syndrome</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>cardiac memory</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>repolarization</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>isointegral maps</value></json:item></subject><articleId><json:string>9680094X</json:string></articleId><language><json:string>eng</json:string></language><abstract>Marked T wave abnormalities in 12-lead electrocardiograms often appear after radiofrequency ablation in patients with Wolff-Parkinson-White (WPW) syndrome. Durations of the QRS complex before ablation have been reported to be significantly greater in patients with repolarization abnormalities after ablation than in those with normal repolarization. However, there has been no report concerning the relationship between QRS duration and repolarization abnormalities before ablation. It has been reported that QRST isointegral maps are dependent on local cellular repolarization properties but largely independent of activation sequence, and that they provide quantitative information about repolarization abnormalities. Isointegral maps were constructed from data recorded in 34 patients with WPW syndrome and QRS durations of 0.1 second or longer (21 patients with left-sided accessory pathways and 13 with right-sided pathways) in order to investigate the relationship between QRS duration and abnormalities in repolarization properties during preexcitation. Body surface ECGs were recorded with an 87-lead system at a sampling interval of 1 ms. The QRST values (mean ± 2SD) from 607 normal individuals were taken to represent the normal range. The area with abnormally low QRST values was designated as the −2SD area and the sum of the QRST values (ΣQRST) in this area was calculated. The QRS duration was found to be significantly related to ΣQRST. These results demonstrate that the patients with WPW syndrome had abnormalities in local repolarization properties that were significantly related to QRS duration during preexcitation. The degree of preexcitation may be important in producing these abnormalities in patients with manifest WPW syndrome. This may result in T wave abnormalities after ablation of the accessory pathway attributable to cardiac memory.</abstract><qualityIndicators><score>8</score><pdfVersion>1.3</pdfVersion><pdfPageSize>576 x 792 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>5</keywordCount><abstractCharCount>1868</abstractCharCount><pdfWordCount>5126</pdfWordCount><pdfCharCount>24735</pdfCharCount><pdfPageCount>8</pdfPageCount><abstractWordCount>268</abstractWordCount></qualityIndicators><title>Relationship between QRS duration and repolarization abnormalities in patients with wolff-parkinson-white syndrome</title><pii><json:string>S0022-0736(96)80094-X</json:string></pii><genre><json:string>research-article</json:string></genre><host><volume>29</volume><pii><json:string>S0022-0736(96)X8090-7</json:string></pii><pages><last>308</last><first>301</first></pages><issn><json:string>0022-0736</json:string></issn><issue>4</issue><genre><json:string>Journal</json:string></genre><language><json:string>unknown</json:string></language><title>Journal of Electrocardiology</title><publicationDate>1996</publicationDate></host><categories><wos><json:string>CARDIAC & CARDIOVASCULAR 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level="a" type="main" xml:lang="en">Relationship between QRS duration and repolarization abnormalities in patients with wolff-parkinson-white syndrome</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>ELSEVIER</publisher><availability><p>ELSEVIER</p></availability><date>1996</date></publicationStmt><notesStmt><note>Supported in part by a Grant-in-Aid for General Scientific Research from the Ministry of Education, Science, Sports, and Culture of Japan and by a Research Grant for Cardiovascular Disease from the Ministry of Health.</note><note type="content">Section title: Original Article</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Relationship between QRS duration and repolarization abnormalities in patients with wolff-parkinson-white syndrome</title><author><persName><forename type="first">Fumi</forename><surname>Inaba-Sato</surname></persName><roleName type="degree">MD</roleName><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation></author><author><persName><forename type="first">Makoto</forename><surname>Hirai</surname></persName><roleName type="degree">MD</roleName><note type="biography">Reprint requests: Makoto Hirai, MD, Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, 65 Tsurumai, Showaku, Nagoya 466, Japan.</note><affiliation>Reprint requests: Makoto Hirai, MD, Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, 65 Tsurumai, Showaku, Nagoya 466, Japan.</affiliation><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation></author><author><persName><forename type="first">Hiroshi</forename><surname>Hayashi</surname></persName><roleName type="degree">MD</roleName><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation></author><author><persName><forename type="first">Yukihiko</forename><surname>Yoshida</surname></persName><roleName type="degree">MD</roleName><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation></author><author><persName><forename type="first">Tetsuo</forename><surname>Yanagawa</surname></persName><roleName type="degree">MD</roleName><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation></author><author><persName><forename type="first">Yasushi</forename><surname>Tomita</surname></persName><roleName type="degree">MD</roleName><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation></author><author><persName><forename type="first">Kazuki</forename><surname>Iwata</surname></persName><roleName type="degree">MD</roleName><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation></author><author><persName><forename type="first">Kazunari</forename><surname>Abe</surname></persName><roleName type="degree">MD</roleName><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation></author><author><persName><forename type="first">Masayuki</forename><surname>Terazawa</surname></persName><roleName type="degree">MD</roleName><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation></author><author><persName><forename type="first">Makoto</forename><surname>Akahoshi</surname></persName><roleName type="degree">MD</roleName><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation></author><author><persName><forename type="first">Mikio</forename><surname>Sugino</surname></persName><roleName type="degree">MD</roleName><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation></author><author><persName><forename type="first">Hidehiko</forename><surname>Saito</surname></persName><roleName type="degree">MD</roleName><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation></author></analytic><monogr><title level="j">Journal of Electrocardiology</title><title level="j" type="abbrev">YJELC</title><idno type="pISSN">0022-0736</idno><idno type="PII">S0022-0736(96)X8090-7</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1996"></date><biblScope unit="volume">29</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="301">301</biblScope><biblScope unit="page" to="308">308</biblScope></imprint></monogr><idno type="istex">B3595E6F7C7BED01507A2CD42E0883156F3154B9</idno><idno type="DOI">10.1016/S0022-0736(96)80094-X</idno><idno type="PII">S0022-0736(96)80094-X</idno><idno type="ArticleID">9680094X</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1996</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Marked T wave abnormalities in 12-lead electrocardiograms often appear after radiofrequency ablation in patients with Wolff-Parkinson-White (WPW) syndrome. Durations of the QRS complex before ablation have been reported to be significantly greater in patients with repolarization abnormalities after ablation than in those with normal repolarization. However, there has been no report concerning the relationship between QRS duration and repolarization abnormalities before ablation. It has been reported that QRST isointegral maps are dependent on local cellular repolarization properties but largely independent of activation sequence, and that they provide quantitative information about repolarization abnormalities. Isointegral maps were constructed from data recorded in 34 patients with WPW syndrome and QRS durations of 0.1 second or longer (21 patients with left-sided accessory pathways and 13 with right-sided pathways) in order to investigate the relationship between QRS duration and abnormalities in repolarization properties during preexcitation. Body surface ECGs were recorded with an 87-lead system at a sampling interval of 1 ms. The QRST values (mean ± 2SD) from 607 normal individuals were taken to represent the normal range. The area with abnormally low QRST values was designated as the −2SD area and the sum of the QRST values (ΣQRST) in this area was calculated. The QRS duration was found to be significantly related to ΣQRST. These results demonstrate that the patients with WPW syndrome had abnormalities in local repolarization properties that were significantly related to QRS duration during preexcitation. The degree of preexcitation may be important in producing these abnormalities in patients with manifest WPW syndrome. This may result in T wave abnormalities after ablation of the accessory pathway attributable to cardiac memory.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Key words</head><item><term>QRST value</term></item><item><term>Wolff-Parkinson-White syndrome</term></item><item><term>cardiac memory</term></item><item><term>repolarization</term></item><item><term>isointegral maps</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="1996">Published</change></revisionDesc></teiHeader></istex:fulltextTEI></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier doc found" wicri:toSee="Elsevier, no converted or simple article"><istex:xmlDeclaration>version="1.0" encoding="utf-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 5.0.1//EN//XML" URI="art501.dtd" name="istex:docType"></istex:docType><istex:document><article version="5.0" xml:lang="en" docsubtype="fla"><item-info><jid>YJELC</jid><aid>9680094X</aid><ce:pii>S0022-0736(96)80094-X</ce:pii><ce:doi>10.1016/S0022-0736(96)80094-X</ce:doi><ce:copyright type="unknown" year="1996">Churchill Livingstone Inc.</ce:copyright></item-info><head><ce:article-footnote><ce:label>*</ce:label><ce:note-para>Supported in part by a Grant-in-Aid for General Scientific Research from the Ministry of Education, Science, Sports, and Culture of Japan and by a Research Grant for Cardiovascular Disease from the Ministry of Health.</ce:note-para></ce:article-footnote><ce:dochead><ce:textfn>Original Article</ce:textfn></ce:dochead><ce:title>Relationship between QRS duration and repolarization abnormalities in patients with wolff-parkinson-white syndrome</ce:title><ce:author-group><ce:author><ce:degrees>MD</ce:degrees><ce:given-name>Fumi</ce:given-name><ce:surname>Inaba-Sato</ce:surname></ce:author><ce:author><ce:degrees>MD</ce:degrees><ce:given-name>Makoto</ce:given-name><ce:surname>Hirai</ce:surname><ce:cross-ref refid="cor1"><ce:sup>1</ce:sup></ce:cross-ref></ce:author><ce:author><ce:degrees>MD</ce:degrees><ce:given-name>Hiroshi</ce:given-name><ce:surname>Hayashi</ce:surname></ce:author><ce:author><ce:degrees>MD</ce:degrees><ce:given-name>Yukihiko</ce:given-name><ce:surname>Yoshida</ce:surname></ce:author><ce:author><ce:degrees>MD</ce:degrees><ce:given-name>Tetsuo</ce:given-name><ce:surname>Yanagawa</ce:surname></ce:author><ce:author><ce:degrees>MD</ce:degrees><ce:given-name>Yasushi</ce:given-name><ce:surname>Tomita</ce:surname></ce:author><ce:author><ce:degrees>MD</ce:degrees><ce:given-name>Kazuki</ce:given-name><ce:surname>Iwata</ce:surname></ce:author><ce:author><ce:degrees>MD</ce:degrees><ce:given-name>Kazunari</ce:given-name><ce:surname>Abe</ce:surname></ce:author><ce:author><ce:degrees>MD</ce:degrees><ce:given-name>Masayuki</ce:given-name><ce:surname>Terazawa</ce:surname></ce:author><ce:author><ce:degrees>MD</ce:degrees><ce:given-name>Makoto</ce:given-name><ce:surname>Akahoshi</ce:surname></ce:author><ce:author><ce:degrees>MD</ce:degrees><ce:given-name>Mikio</ce:given-name><ce:surname>Sugino</ce:surname></ce:author><ce:author><ce:degrees>MD</ce:degrees><ce:given-name>Hidehiko</ce:given-name><ce:surname>Saito</ce:surname></ce:author><ce:affiliation id="aff1"><ce:textfn>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</ce:textfn></ce:affiliation><ce:correspondence id="cor1"><ce:label>1</ce:label><ce:text>Reprint requests: Makoto Hirai, MD, Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, 65 Tsurumai, Showaku, Nagoya 466, Japan.</ce:text></ce:correspondence></ce:author-group><ce:abstract id="ab1" class="author" xml:lang="en"><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:simple-para>Marked T wave abnormalities in 12-lead electrocardiograms often appear after radiofrequency ablation in patients with Wolff-Parkinson-White (WPW) syndrome. Durations of the QRS complex before ablation have been reported to be significantly greater in patients with repolarization abnormalities after ablation than in those with normal repolarization. However, there has been no report concerning the relationship between QRS duration and repolarization abnormalities before ablation. It has been reported that QRST isointegral maps are dependent on local cellular repolarization properties but largely independent of activation sequence, and that they provide quantitative information about repolarization abnormalities. Isointegral maps were constructed from data recorded in 34 patients with WPW syndrome and QRS durations of 0.1 second or longer (21 patients with left-sided accessory pathways and 13 with right-sided pathways) in order to investigate the relationship between QRS duration and abnormalities in repolarization properties during preexcitation. Body surface ECGs were recorded with an 87-lead system at a sampling interval of 1 ms. The QRST values (mean ± 2SD) from 607 normal individuals were taken to represent the normal range. The area with abnormally low QRST values was designated as the −2SD area and the sum of the QRST values (ΣQRST) in this area was calculated. The QRS duration was found to be significantly related to ΣQRST. These results demonstrate that the patients with WPW syndrome had abnormalities in local repolarization properties that were significantly related to QRS duration during preexcitation. The degree of preexcitation may be important in producing these abnormalities in patients with manifest WPW syndrome. This may result in T wave abnormalities after ablation of the accessory pathway attributable to cardiac memory.</ce:simple-para></ce:abstract-sec></ce:abstract><ce:keywords class="keyword" xml:lang="en"><ce:section-title>Key words</ce:section-title><ce:keyword><ce:text>QRST value</ce:text></ce:keyword><ce:keyword><ce:text>Wolff-Parkinson-White syndrome</ce:text></ce:keyword><ce:keyword><ce:text>cardiac memory</ce:text></ce:keyword><ce:keyword><ce:text>repolarization</ce:text></ce:keyword><ce:keyword><ce:text>isointegral maps</ce:text></ce:keyword></ce:keywords></head><tail><ce:bibliography><ce:section-title>References</ce:section-title><ce:bibliography-sec><ce:bib-reference id="bib1"><ce:label>1.</ce:label><sb:reference><sb:contribution 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langtype="en"><sb:authors><sb:author><ce:surname>Geller</ce:surname><ce:given-name>JC</ce:given-name></sb:author><sb:author><ce:surname>Rosen</ce:surname><ce:given-name>MR</ce:given-name></sb:author></sb:authors><sb:title><sb:maintitle>Persistent T-wave changes after alteration of the ventricular activation sequence</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Circulation</sb:maintitle></sb:title><sb:volume-nr>88</sb:volume-nr></sb:series><sb:date>1993</sb:date></sb:issue><sb:pages><sb:first-page>1811</sb:first-page></sb:pages></sb:host></sb:reference></ce:bib-reference></ce:bibliography-sec></ce:bibliography></tail></article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Relationship between QRS duration and repolarization abnormalities in patients with wolff-parkinson-white syndrome</title></titleInfo><titleInfo type="alternative" lang="en" contentType="CDATA"><title>Relationship between QRS duration and repolarization abnormalities in patients with wolff-parkinson-white syndrome</title></titleInfo><name type="personal"><namePart type="given">Fumi</namePart><namePart type="family">Inaba-Sato</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Makoto</namePart><namePart type="family">Hirai</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation><description>Reprint requests: Makoto Hirai, MD, Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, 65 Tsurumai, Showaku, Nagoya 466, Japan.</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hiroshi</namePart><namePart type="family">Hayashi</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yukihiko</namePart><namePart type="family">Yoshida</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Tetsuo</namePart><namePart type="family">Yanagawa</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yasushi</namePart><namePart type="family">Tomita</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Kazuki</namePart><namePart type="family">Iwata</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Kazunari</namePart><namePart type="family">Abe</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Masayuki</namePart><namePart type="family">Terazawa</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Makoto</namePart><namePart type="family">Akahoshi</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Mikio</namePart><namePart type="family">Sugino</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hidehiko</namePart><namePart type="family">Saito</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>From the Division of Cardiology, First Department of Internal Medicine, University of Nagoya School of Medicine, Nagoya, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article"></genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1996</dateIssued><copyrightDate encoding="w3cdtf">1996</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">Marked T wave abnormalities in 12-lead electrocardiograms often appear after radiofrequency ablation in patients with Wolff-Parkinson-White (WPW) syndrome. Durations of the QRS complex before ablation have been reported to be significantly greater in patients with repolarization abnormalities after ablation than in those with normal repolarization. However, there has been no report concerning the relationship between QRS duration and repolarization abnormalities before ablation. It has been reported that QRST isointegral maps are dependent on local cellular repolarization properties but largely independent of activation sequence, and that they provide quantitative information about repolarization abnormalities. Isointegral maps were constructed from data recorded in 34 patients with WPW syndrome and QRS durations of 0.1 second or longer (21 patients with left-sided accessory pathways and 13 with right-sided pathways) in order to investigate the relationship between QRS duration and abnormalities in repolarization properties during preexcitation. Body surface ECGs were recorded with an 87-lead system at a sampling interval of 1 ms. The QRST values (mean ± 2SD) from 607 normal individuals were taken to represent the normal range. The area with abnormally low QRST values was designated as the −2SD area and the sum of the QRST values (ΣQRST) in this area was calculated. The QRS duration was found to be significantly related to ΣQRST. These results demonstrate that the patients with WPW syndrome had abnormalities in local repolarization properties that were significantly related to QRS duration during preexcitation. The degree of preexcitation may be important in producing these abnormalities in patients with manifest WPW syndrome. This may result in T wave abnormalities after ablation of the accessory pathway attributable to cardiac memory.</abstract><note>Supported in part by a Grant-in-Aid for General Scientific Research from the Ministry of Education, Science, Sports, and Culture of Japan and by a Research Grant for Cardiovascular Disease from the Ministry of Health.</note><note type="content">Section title: Original Article</note><subject lang="en"><genre>Key words</genre><topic>QRST value</topic><topic>Wolff-Parkinson-White syndrome</topic><topic>cardiac memory</topic><topic>repolarization</topic><topic>isointegral maps</topic></subject><relatedItem type="host"><titleInfo><title>Journal of Electrocardiology</title></titleInfo><titleInfo type="abbreviated"><title>YJELC</title></titleInfo><genre type="Journal">journal</genre><originInfo><dateIssued encoding="w3cdtf">199610</dateIssued></originInfo><identifier type="ISSN">0022-0736</identifier><identifier type="PII">S0022-0736(96)X8090-7</identifier><part><detail type="volume"><number>29</number><caption>vol.</caption></detail><detail type="issue"><number>4</number><caption>no.</caption></detail><extent unit="issue pages"><start>257</start><end>356</end></extent><extent unit="pages"><start>301</start><end>308</end></extent></part></relatedItem><identifier type="istex">B3595E6F7C7BED01507A2CD42E0883156F3154B9</identifier><identifier type="DOI">10.1016/S0022-0736(96)80094-X</identifier><identifier type="PII">S0022-0736(96)80094-X</identifier><identifier type="ArticleID">9680094X</identifier><accessCondition type="use and reproduction" contentType="">© 1996Churchill Livingstone Inc.</accessCondition><recordInfo><recordContentSource>ELSEVIER</recordContentSource><recordOrigin>Churchill Livingstone Inc., ©1996</recordOrigin></recordInfo></mods></metadata><enrichments><istex:catWosTEI uri="https://api.istex.fr/document/B3595E6F7C7BED01507A2CD42E0883156F3154B9/enrichments/catWos"><teiHeader><profileDesc><textClass><classCode scheme="WOS">CARDIAC & CARDIOVASCULAR SYSTEMS</classCode></textClass></profileDesc></teiHeader></istex:catWosTEI></enrichments><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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