ParkinsonFranceV1, PubMed, Curation, bibRecord, 001189

Influence of age on the potential risk of sudden death in asymptomatic Wolff-Parkinson-White syndrome.

Identifieur interne : 001189 ( PubMed/Curation ); précédent : 001188; suivant : 001190

Influence of age on the potential risk of sudden death in asymptomatic Wolff-Parkinson-White syndrome.

Auteurs : B. Brembilla-Perrot [France] ; I. Holban ; P. Houriez ; O. Claudon ; D. Beurrier ; A C Vançon

Source :

Pacing and clinical electrophysiology : PACE [ 0147-8389 ] ; 2001.

RBID : pubmed:11707045

English descriptors

KwdEn :
- Adolescent, Adult, Age Factors, Aged, Child, Death, Sudden (epidemiology), Death, Sudden (etiology), Electrocardiography, Female, Follow-Up Studies, Humans, Male, Middle Aged, Risk Factors, Wolff-Parkinson-White Syndrome (complications), Wolff-Parkinson-White Syndrome (physiopathology).
MESH :
- complications : Wolff-Parkinson-White Syndrome.
- epidemiology : Death, Sudden.
- etiology : Death, Sudden.
- physiopathology : Wolff-Parkinson-White Syndrome.
- Adolescent, Adult, Age Factors, Aged, Child, Electrocardiography, Female, Follow-Up Studies, Humans, Male, Middle Aged, Risk Factors.

Abstract

Sudden death might be the first event in patients with asymptomatic WPW. The purpose of the study was to know if the age of the patient modifies the electrophysiological characteristics of asymptomatic WPW. Transesophageal stimulation was performed on 92 asymptomatic WPW patients from the following age groups: 10-69 years (n = 14), 20-29 years (n = 33), 30-39 years (n = 15), 40-49 years (n = 17), and 50-69 years (n = 13). The procedure consisted of atrial pacing up to the second AV block, programmed atrial stimulation using one and two extrastimuli delivered on two driven rhythms in the control state, and after infusion of isoproterenol. In thefive age groups, paroxysmal junctional tachycardia occurred, respectively, in 1 (7%), 1 (3%), 2 (13%), 2 (12%) patients, and not at all in the oldest group. AF > 1 minute occurred, respectively, in 3 (21%), 9 (27%), 5 (33%), 3 (18%), and 4 (31%) patients. The dangerous form of WPW (rapid conduction in the Kent bundle > 240/min in the control state or > 300/min after isoproterenol + AF induction) occurred, respectively, in 3 (21%), 9 (27%), 4 (27%), 1 (6%), and 3 (23%) patients. In conclusion, electrophysiological data of asymptomatic WPW are not modified by age of the patient. Elderly patients remain at risk of a dangerous form of WPW; systematic evaluation of WPWis recommended in patients with an active life independent of age.

PubMed: 11707045

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Le document en format XML

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<author><name sortKey="Brembilla Perrot, B" sort="Brembilla Perrot, B" uniqKey="Brembilla Perrot B" first="B" last="Brembilla-Perrot">B. Brembilla-Perrot</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, CHU of Brabois, Vandoeuvre, France. b.brembilla-perrot@chu-nancy.fr</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Cardiology, CHU of Brabois, Vandoeuvre</wicri:regionArea>
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<author><name sortKey="Holban, I" sort="Holban, I" uniqKey="Holban I" first="I" last="Holban">I. Holban</name>
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<author><name sortKey="Houriez, P" sort="Houriez, P" uniqKey="Houriez P" first="P" last="Houriez">P. Houriez</name>
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<author><name sortKey="Claudon, O" sort="Claudon, O" uniqKey="Claudon O" first="O" last="Claudon">O. Claudon</name>
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<author><name sortKey="Beurrier, D" sort="Beurrier, D" uniqKey="Beurrier D" first="D" last="Beurrier">D. Beurrier</name>
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<author><name sortKey="Vancon, A C" sort="Vancon, A C" uniqKey="Vancon A" first="A C" last="Vançon">A C Vançon</name>
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<term>Death, Sudden (epidemiology)</term>
<term>Death, Sudden (etiology)</term>
<term>Electrocardiography</term>
<term>Female</term>
<term>Follow-Up Studies</term>
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<term>Risk Factors</term>
<term>Wolff-Parkinson-White Syndrome (complications)</term>
<term>Wolff-Parkinson-White Syndrome (physiopathology)</term>
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<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Wolff-Parkinson-White Syndrome</term>
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<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Age Factors</term>
<term>Aged</term>
<term>Child</term>
<term>Electrocardiography</term>
<term>Female</term>
<term>Follow-Up Studies</term>
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<front><div type="abstract" xml:lang="en">Sudden death might be the first event in patients with asymptomatic WPW. The purpose of the study was to know if the age of the patient modifies the electrophysiological characteristics of asymptomatic WPW. Transesophageal stimulation was performed on 92 asymptomatic WPW patients from the following age groups: 10-69 years (n = 14), 20-29 years (n = 33), 30-39 years (n = 15), 40-49 years (n = 17), and 50-69 years (n = 13). The procedure consisted of atrial pacing up to the second AV block, programmed atrial stimulation using one and two extrastimuli delivered on two driven rhythms in the control state, and after infusion of isoproterenol. In thefive age groups, paroxysmal junctional tachycardia occurred, respectively, in 1 (7%), 1 (3%), 2 (13%), 2 (12%) patients, and not at all in the oldest group. AF > 1 minute occurred, respectively, in 3 (21%), 9 (27%), 5 (33%), 3 (18%), and 4 (31%) patients. The dangerous form of WPW (rapid conduction in the Kent bundle > 240/min in the control state or > 300/min after isoproterenol + AF induction) occurred, respectively, in 3 (21%), 9 (27%), 4 (27%), 1 (6%), and 3 (23%) patients. In conclusion, electrophysiological data of asymptomatic WPW are not modified by age of the patient. Elderly patients remain at risk of a dangerous form of WPW; systematic evaluation of WPWis recommended in patients with an active life independent of age.</div>
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<Title>Pacing and clinical electrophysiology : PACE</Title>
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<ArticleTitle>Influence of age on the potential risk of sudden death in asymptomatic Wolff-Parkinson-White syndrome.</ArticleTitle>
<Pagination><MedlinePgn>1514-8</MedlinePgn>
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<Abstract><AbstractText>Sudden death might be the first event in patients with asymptomatic WPW. The purpose of the study was to know if the age of the patient modifies the electrophysiological characteristics of asymptomatic WPW. Transesophageal stimulation was performed on 92 asymptomatic WPW patients from the following age groups: 10-69 years (n = 14), 20-29 years (n = 33), 30-39 years (n = 15), 40-49 years (n = 17), and 50-69 years (n = 13). The procedure consisted of atrial pacing up to the second AV block, programmed atrial stimulation using one and two extrastimuli delivered on two driven rhythms in the control state, and after infusion of isoproterenol. In thefive age groups, paroxysmal junctional tachycardia occurred, respectively, in 1 (7%), 1 (3%), 2 (13%), 2 (12%) patients, and not at all in the oldest group. AF > 1 minute occurred, respectively, in 3 (21%), 9 (27%), 5 (33%), 3 (18%), and 4 (31%) patients. The dangerous form of WPW (rapid conduction in the Kent bundle > 240/min in the control state or > 300/min after isoproterenol + AF induction) occurred, respectively, in 3 (21%), 9 (27%), 4 (27%), 1 (6%), and 3 (23%) patients. In conclusion, electrophysiological data of asymptomatic WPW are not modified by age of the patient. Elderly patients remain at risk of a dangerous form of WPW; systematic evaluation of WPWis recommended in patients with an active life independent of age.</AbstractText>
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<MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName>
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Influence of age on the potential risk of sudden death in asymptomatic Wolff-Parkinson-White syndrome.

Influence of age on the potential risk of sudden death in asymptomatic Wolff-Parkinson-White syndrome.

Source :

English descriptors

Abstract

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