Does subthalamic nucleus stimulation induce apathy in Parkinson's disease?
Identifieur interne : 000E14 ( PubMed/Curation ); précédent : 000E13; suivant : 000E15Does subthalamic nucleus stimulation induce apathy in Parkinson's disease?
Auteurs : D. Drapier [France] ; S. Drapier ; P. Sauleau ; C. Haegelen ; S. Raoul ; I. Biseul ; J. Peron ; F. Lallement ; I. Rivier ; J M Reymann ; G. Edan ; M. Verin ; B. MilletSource :
- Journal of neurology [ 0340-5354 ] ; 2006.
English descriptors
- KwdEn :
- Aged, Analysis of Variance, Anxiety (etiology), Deep Brain Stimulation (adverse effects), Depression (etiology), Electrodes, Implanted, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Parkinson Disease (complications), Parkinson Disease (physiopathology), Parkinson Disease (surgery), Parkinson Disease (therapy), Severity of Illness Index, Sleep Stages, Subthalamic Nucleus, Time Factors, Treatment Outcome.
- MESH :
- adverse effects : Deep Brain Stimulation.
- complications : Parkinson Disease.
- etiology : Anxiety, Depression.
- physiopathology : Parkinson Disease.
- surgery : Parkinson Disease.
- therapy : Parkinson Disease.
- Aged, Analysis of Variance, Electrodes, Implanted, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Severity of Illness Index, Sleep Stages, Subthalamic Nucleus, Time Factors, Treatment Outcome.
Abstract
Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) has been shown to significantly improve motor symptoms in advanced Parkinson's disease (PD). Only few studies, however, have focused on the non-motor effects of DBS.
DOI: 10.1007/s00415-006-0177-0
PubMed: 16607469
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000E54
Links to Exploration step
pubmed:16607469Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Does subthalamic nucleus stimulation induce apathy in Parkinson's disease?</title><author><name sortKey="Drapier, D" sort="Drapier, D" uniqKey="Drapier D" first="D" last="Drapier">D. Drapier</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychiatry, Centre Hospitalier Guillaume Régnier, 108 Avenue du Général Leclerc, 35703 Rennes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Psychiatry, Centre Hospitalier Guillaume Régnier, 108 Avenue du Général Leclerc, 35703 Rennes</wicri:regionArea></affiliation></author><author><name sortKey="Drapier, S" sort="Drapier, S" uniqKey="Drapier S" first="S" last="Drapier">S. Drapier</name></author><author><name sortKey="Sauleau, P" sort="Sauleau, P" uniqKey="Sauleau P" first="P" last="Sauleau">P. Sauleau</name></author><author><name sortKey="Haegelen, C" sort="Haegelen, C" uniqKey="Haegelen C" first="C" last="Haegelen">C. Haegelen</name></author><author><name sortKey="Raoul, S" sort="Raoul, S" uniqKey="Raoul S" first="S" last="Raoul">S. Raoul</name></author><author><name sortKey="Biseul, I" sort="Biseul, I" uniqKey="Biseul I" first="I" last="Biseul">I. Biseul</name></author><author><name sortKey="Peron, J" sort="Peron, J" uniqKey="Peron J" first="J" last="Peron">J. Peron</name></author><author><name sortKey="Lallement, F" sort="Lallement, F" uniqKey="Lallement F" first="F" last="Lallement">F. Lallement</name></author><author><name sortKey="Rivier, I" sort="Rivier, I" uniqKey="Rivier I" first="I" last="Rivier">I. Rivier</name></author><author><name sortKey="Reymann, J M" sort="Reymann, J M" uniqKey="Reymann J" first="J M" last="Reymann">J M Reymann</name></author><author><name sortKey="Edan, G" sort="Edan, G" uniqKey="Edan G" first="G" last="Edan">G. Edan</name></author><author><name sortKey="Verin, M" sort="Verin, M" uniqKey="Verin M" first="M" last="Verin">M. Verin</name></author><author><name sortKey="Millet, B" sort="Millet, B" uniqKey="Millet B" first="B" last="Millet">B. Millet</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2006">2006</date><idno type="RBID">pubmed:16607469</idno><idno type="pmid">16607469</idno><idno type="doi">10.1007/s00415-006-0177-0</idno><idno type="wicri:Area/PubMed/Corpus">000E54</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000E54</idno><idno type="wicri:Area/PubMed/Curation">000E14</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000E14</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Does subthalamic nucleus stimulation induce apathy in Parkinson's disease?</title><author><name sortKey="Drapier, D" sort="Drapier, D" uniqKey="Drapier D" first="D" last="Drapier">D. Drapier</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychiatry, Centre Hospitalier Guillaume Régnier, 108 Avenue du Général Leclerc, 35703 Rennes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Psychiatry, Centre Hospitalier Guillaume Régnier, 108 Avenue du Général Leclerc, 35703 Rennes</wicri:regionArea></affiliation></author><author><name sortKey="Drapier, S" sort="Drapier, S" uniqKey="Drapier S" first="S" last="Drapier">S. Drapier</name></author><author><name sortKey="Sauleau, P" sort="Sauleau, P" uniqKey="Sauleau P" first="P" last="Sauleau">P. Sauleau</name></author><author><name sortKey="Haegelen, C" sort="Haegelen, C" uniqKey="Haegelen C" first="C" last="Haegelen">C. Haegelen</name></author><author><name sortKey="Raoul, S" sort="Raoul, S" uniqKey="Raoul S" first="S" last="Raoul">S. Raoul</name></author><author><name sortKey="Biseul, I" sort="Biseul, I" uniqKey="Biseul I" first="I" last="Biseul">I. Biseul</name></author><author><name sortKey="Peron, J" sort="Peron, J" uniqKey="Peron J" first="J" last="Peron">J. Peron</name></author><author><name sortKey="Lallement, F" sort="Lallement, F" uniqKey="Lallement F" first="F" last="Lallement">F. Lallement</name></author><author><name sortKey="Rivier, I" sort="Rivier, I" uniqKey="Rivier I" first="I" last="Rivier">I. Rivier</name></author><author><name sortKey="Reymann, J M" sort="Reymann, J M" uniqKey="Reymann J" first="J M" last="Reymann">J M Reymann</name></author><author><name sortKey="Edan, G" sort="Edan, G" uniqKey="Edan G" first="G" last="Edan">G. Edan</name></author><author><name sortKey="Verin, M" sort="Verin, M" uniqKey="Verin M" first="M" last="Verin">M. Verin</name></author><author><name sortKey="Millet, B" sort="Millet, B" uniqKey="Millet B" first="B" last="Millet">B. Millet</name></author></analytic><series><title level="j">Journal of neurology</title><idno type="ISSN">0340-5354</idno><imprint><date when="2006" type="published">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Analysis of Variance</term><term>Anxiety (etiology)</term><term>Deep Brain Stimulation (adverse effects)</term><term>Depression (etiology)</term><term>Electrodes, Implanted</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>Parkinson Disease (complications)</term><term>Parkinson Disease (physiopathology)</term><term>Parkinson Disease (surgery)</term><term>Parkinson Disease (therapy)</term><term>Severity of Illness Index</term><term>Sleep Stages</term><term>Subthalamic Nucleus</term><term>Time Factors</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Deep Brain Stimulation</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Anxiety</term><term>Depression</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Analysis of Variance</term><term>Electrodes, Implanted</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>Severity of Illness Index</term><term>Sleep Stages</term><term>Subthalamic Nucleus</term><term>Time Factors</term><term>Treatment Outcome</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) has been shown to significantly improve motor symptoms in advanced Parkinson's disease (PD). Only few studies, however, have focused on the non-motor effects of DBS.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">16607469</PMID><DateCreated><Year>2006</Year><Month>09</Month><Day>25</Day></DateCreated><DateCompleted><Year>2006</Year><Month>10</Month><Day>26</Day></DateCompleted><DateRevised><Year>2006</Year><Month>09</Month><Day>25</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">0340-5354</ISSN><JournalIssue CitedMedium="Print"><Volume>253</Volume><Issue>8</Issue><PubDate><Year>2006</Year><Month>Aug</Month></PubDate></JournalIssue><Title>Journal of neurology</Title><ISOAbbreviation>J. Neurol.</ISOAbbreviation></Journal><ArticleTitle>Does subthalamic nucleus stimulation induce apathy in Parkinson's disease?</ArticleTitle><Pagination><MedlinePgn>1083-91</MedlinePgn></Pagination><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) has been shown to significantly improve motor symptoms in advanced Parkinson's disease (PD). Only few studies, however, have focused on the non-motor effects of DBS.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">A consecutive series of 15 patients was assessed three months before (M-3), then three months (M3) and six months (M6) after surgery. Mean (+/- SD) age at surgery was 59.7 (7.6). Mean disease duration at surgery was 12.2 (2.8) years. The Mini International Neuropsychiatric Inventory was used to assess psychiatric disorders three months before surgery. Depression was evaluated using Montgomery and Asberg Rating Scale (MADRS). Anxiety was evaluated using the AMDP system (Association for Methodology and Documentation in Psychiatry). Apathy was particularly evaluated using the Apathy Evaluation Scale (AES) and the Starkstein Scale. All these scales were performed at every evaluation.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Apathy worsened at M3 and M6 after STN-DBS in comparison with the preoperative evaluation: the AES mean score was significantly impaired between the preoperative (38.4+/-7.1) and both the postoperative M3 (44.6+/-9.5, p = 0.003) and M6 scores (46.0+/-10.9, p = 0.013). Significant worsening of apathy was confirmed using the Starkstein scale. There was no evidence of depression: the mean MADRS score did not differ before surgery (9.1+/-7.4) and at both M3 (8.6+/-8.2) and M6 (9.9+/-7.7) after STN-DBS. The anxiety level did not change between preoperative (9.4+/-9.2) and both M3 (5.5+/-4.5) and M6 (6.6+/-4.6) postoperative states.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Although STN-DBS constitutes a therapeutic advance for severely disabled patients with Parkinson's disease, we should keep in mind that this surgical procedure may contribute to the inducing of apathy. Our observation raises the issue of the direct influence of STN- DBS on the limbic system by diffusion of stimulus to the medial limbic compartment of STN.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Drapier</LastName><ForeName>D</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, Centre Hospitalier Guillaume Régnier, 108 Avenue du Général Leclerc, 35703 Rennes, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Drapier</LastName><ForeName>S</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Sauleau</LastName><ForeName>P</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Haegelen</LastName><ForeName>C</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Raoul</LastName><ForeName>S</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Biseul</LastName><ForeName>I</ForeName><Initials>I</Initials></Author><Author ValidYN="Y"><LastName>Peron</LastName><ForeName>J</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Lallement</LastName><ForeName>F</ForeName><Initials>F</Initials></Author><Author ValidYN="Y"><LastName>Rivier</LastName><ForeName>I</ForeName><Initials>I</Initials></Author><Author ValidYN="Y"><LastName>Reymann</LastName><ForeName>J M</ForeName><Initials>JM</Initials></Author><Author ValidYN="Y"><LastName>Edan</LastName><ForeName>G</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Verin</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Millet</LastName><ForeName>B</ForeName><Initials>B</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D018848">Controlled Clinical Trial</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2006</Year><Month>04</Month><Day>10</Day></ArticleDate></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>J Neurol</MedlineTA><NlmUniqueID>0423161</NlmUniqueID><ISSNLinking>0340-5354</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000704" MajorTopicYN="N">Analysis of Variance</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001007" MajorTopicYN="N">Anxiety</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D046690" MajorTopicYN="N">Deep Brain Stimulation</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003863" MajorTopicYN="N">Depression</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004567" MajorTopicYN="N">Electrodes, Implanted</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009483" MajorTopicYN="N">Neuropsychological Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName><QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012720" MajorTopicYN="N">Severity of Illness Index</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012894" MajorTopicYN="Y">Sleep Stages</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020531" MajorTopicYN="Y">Subthalamic Nucleus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2005</Year><Month>07</Month><Day>07</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2005</Year><Month>12</Month><Day>06</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2005</Year><Month>10</Month><Day>09</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2006</Year><Month>4</Month><Day>12</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2006</Year><Month>10</Month><Day>27</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2006</Year><Month>4</Month><Day>12</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">16607469</ArticleId><ArticleId IdType="doi">10.1007/s00415-006-0177-0</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000E14 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 000E14 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonFranceV1
|flux= PubMed
|étape= Curation
|type= RBID
|clé= pubmed:16607469
|texte= Does subthalamic nucleus stimulation induce apathy in Parkinson's disease?
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:16607469" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \
| NlmPubMed2Wicri -a ParkinsonFranceV1
| This area was generated with Dilib version V0.6.29. |  |