ParkinsonFranceV1, PubMed, Corpus, bibRecord, 001485

Neuropsychological prediction of dementia in Parkinson's disease.

Identifieur interne : 001485 ( PubMed/Corpus ); précédent : 001484; suivant : 001486

Neuropsychological prediction of dementia in Parkinson's disease.

Auteurs : F. Mahieux ; G. Fénelon ; A. Flahault ; M J Manifacier ; D. Michelet ; F. Boller

Source :

Journal of neurology, neurosurgery, and psychiatry [ 0022-3050 ] ; 1998.

RBID : pubmed:9489527

English descriptors

KwdEn :
- Aged, Cognition Disorders (diagnosis), Cognition Disorders (etiology), Female, Follow-Up Studies, Humans, Male, Middle Aged, Neuropsychological Tests, Parkinson Disease (complications), Predictive Value of Tests, Severity of Illness Index.
MESH :
- complications : Parkinson Disease.
- diagnosis : Cognition Disorders.
- etiology : Cognition Disorders.
- Aged, Female, Follow-Up Studies, Humans, Male, Middle Aged, Neuropsychological Tests, Predictive Value of Tests, Severity of Illness Index.

Abstract

To identify neuropsychological characteristics predictive of later dementia in Parkinson's disease.

PubMed: 9489527

Links to Exploration step

pubmed:9489527

Le document en format XML

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<author><name sortKey="Mahieux, F" sort="Mahieux, F" uniqKey="Mahieux F" first="F" last="Mahieux">F. Mahieux</name>
<affiliation><nlm:affiliation>Service de Neurologie, Hôpital Tenon, Paris, France.</nlm:affiliation>
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<author><name sortKey="Fenelon, G" sort="Fenelon, G" uniqKey="Fenelon G" first="G" last="Fénelon">G. Fénelon</name>
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<author><name sortKey="Flahault, A" sort="Flahault, A" uniqKey="Flahault A" first="A" last="Flahault">A. Flahault</name>
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<author><name sortKey="Manifacier, M J" sort="Manifacier, M J" uniqKey="Manifacier M" first="M J" last="Manifacier">M J Manifacier</name>
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<author><name sortKey="Michelet, D" sort="Michelet, D" uniqKey="Michelet D" first="D" last="Michelet">D. Michelet</name>
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<author><name sortKey="Boller, F" sort="Boller, F" uniqKey="Boller F" first="F" last="Boller">F. Boller</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Neuropsychological prediction of dementia in Parkinson's disease.</title>
<author><name sortKey="Mahieux, F" sort="Mahieux, F" uniqKey="Mahieux F" first="F" last="Mahieux">F. Mahieux</name>
<affiliation><nlm:affiliation>Service de Neurologie, Hôpital Tenon, Paris, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Fenelon, G" sort="Fenelon, G" uniqKey="Fenelon G" first="G" last="Fénelon">G. Fénelon</name>
</author>
<author><name sortKey="Flahault, A" sort="Flahault, A" uniqKey="Flahault A" first="A" last="Flahault">A. Flahault</name>
</author>
<author><name sortKey="Manifacier, M J" sort="Manifacier, M J" uniqKey="Manifacier M" first="M J" last="Manifacier">M J Manifacier</name>
</author>
<author><name sortKey="Michelet, D" sort="Michelet, D" uniqKey="Michelet D" first="D" last="Michelet">D. Michelet</name>
</author>
<author><name sortKey="Boller, F" sort="Boller, F" uniqKey="Boller F" first="F" last="Boller">F. Boller</name>
</author>
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<series><title level="j">Journal of neurology, neurosurgery, and psychiatry</title>
<idno type="ISSN">0022-3050</idno>
<imprint><date when="1998" type="published">1998</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Cognition Disorders (diagnosis)</term>
<term>Cognition Disorders (etiology)</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neuropsychological Tests</term>
<term>Parkinson Disease (complications)</term>
<term>Predictive Value of Tests</term>
<term>Severity of Illness Index</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Cognition Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cognition Disorders</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neuropsychological Tests</term>
<term>Predictive Value of Tests</term>
<term>Severity of Illness Index</term>
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<front><div type="abstract" xml:lang="en">To identify neuropsychological characteristics predictive of later dementia in Parkinson's disease.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">9489527</PMID>
<DateCreated><Year>1998</Year>
<Month>03</Month>
<Day>24</Day>
</DateCreated>
<DateCompleted><Year>1998</Year>
<Month>03</Month>
<Day>24</Day>
</DateCompleted>
<DateRevised><Year>2014</Year>
<Month>06</Month>
<Day>17</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0022-3050</ISSN>
<JournalIssue CitedMedium="Print"><Volume>64</Volume>
<Issue>2</Issue>
<PubDate><Year>1998</Year>
<Month>Feb</Month>
</PubDate>
</JournalIssue>
<Title>Journal of neurology, neurosurgery, and psychiatry</Title>
<ISOAbbreviation>J. Neurol. Neurosurg. Psychiatr.</ISOAbbreviation>
</Journal>
<ArticleTitle>Neuropsychological prediction of dementia in Parkinson's disease.</ArticleTitle>
<Pagination><MedlinePgn>178-83</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To identify neuropsychological characteristics predictive of later dementia in Parkinson's disease.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">A comprehensive neuropsychological test battery was administered to a cohort of 89 initially non-demented patients with Parkinson's disease consecutively enrolled at a specialised Parkinson's disease clinic. They were reassessed after a mean of 3.5 years for the diagnosis of dementia. The Cox proportional hazards model was used to identify baseline characteristics predictive of dementia.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Only four of the baseline clinical characteristics of Parkinson's disease and neuropsychological variables remained independently linked to subsequent development of dementia: the age of onset of Parkinson's disease (>60 years; relative risk (RR) 4.1, 95% confidence interval (95% CI) 1.8-24.0, p<0.03), the picture completion subtest of the Wechsler adult intelligence scale (score<10; RR 4.9, 95% CI 1.0-24.1, p<0.02), the interference section of the Stroop test (score<21; RR 3.8, p=0.08), and a verbal fluency task (score<9; RR 2.7, 95% CI 0.8-9.1, p=0.09). Depressive symptoms and the severity of motor impairment were not predictive of dementia.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">These features are different from the neuropsychological characteristics predictive of Alzheimer's dementia in healthy elderly people (mainly memory and language performance). They are in keeping with the well known specificity of the impairments in Parkinson's disease for visuospatial abilities and difficulties in inhibiting irrelevant stimuli. It is postulated that the composite nature of the picture completion subtest, involving several cognitive abilities impaired in Parkinson's disease, explains its sensitivity.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Mahieux</LastName>
<ForeName>F</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Service de Neurologie, Hôpital Tenon, Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fénelon</LastName>
<ForeName>G</ForeName>
<Initials>G</Initials>
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<Author ValidYN="Y"><LastName>Flahault</LastName>
<ForeName>A</ForeName>
<Initials>A</Initials>
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<Author ValidYN="Y"><LastName>Manifacier</LastName>
<ForeName>M J</ForeName>
<Initials>MJ</Initials>
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<Author ValidYN="Y"><LastName>Michelet</LastName>
<ForeName>D</ForeName>
<Initials>D</Initials>
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<Author ValidYN="Y"><LastName>Boller</LastName>
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<Language>eng</Language>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003072" MajorTopicYN="N">Cognition Disorders</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005500" MajorTopicYN="N">Follow-Up Studies</DescriptorName>
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<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
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<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
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<MeshHeading><DescriptorName UI="D009483" MajorTopicYN="N">Neuropsychological Tests</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
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<MeshHeading><DescriptorName UI="D011237" MajorTopicYN="N">Predictive Value of Tests</DescriptorName>
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	La maladie de Parkinson en France (serveur d'exploration)
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La maladie de Parkinson en France (serveur d'exploration)

Neuropsychological prediction of dementia in Parkinson's disease.

Neuropsychological prediction of dementia in Parkinson's disease.

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Abstract

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