ParkinsonFranceV1, PubMed, Corpus, bibRecord, 001172

Nonmotor fluctuations in Parkinson's disease: frequent and disabling.

Identifieur interne : 001172 ( PubMed/Corpus ); précédent : 001171; suivant : 001173

Nonmotor fluctuations in Parkinson's disease: frequent and disabling.

Auteurs : Tatiana Witjas ; E. Kaphan ; J P Azulay ; O. Blin ; M. Ceccaldi ; J. Pouget ; M. Poncet ; A Ali Chérif

Source :

Neurology [ 0028-3878 ] ; 2002.

RBID : pubmed:12177375

English descriptors

KwdEn :
- Aged, Autonomic Nervous System Diseases (epidemiology), Autonomic Nervous System Diseases (physiopathology), Autonomic Nervous System Diseases (psychology), Chi-Square Distribution, Cognition Disorders (epidemiology), Cognition Disorders (physiopathology), Cognition Disorders (psychology), Female, Humans, Male, Middle Aged, Parkinson Disease (epidemiology), Parkinson Disease (physiopathology), Parkinson Disease (psychology), Prospective Studies, Sensation Disorders (epidemiology), Sensation Disorders (physiopathology), Sensation Disorders (psychology), Statistics, Nonparametric, Surveys and Questionnaires.
MESH :
- epidemiology : Autonomic Nervous System Diseases, Cognition Disorders, Parkinson Disease, Sensation Disorders.
- physiopathology : Autonomic Nervous System Diseases, Cognition Disorders, Parkinson Disease, Sensation Disorders.
- psychology : Autonomic Nervous System Diseases, Cognition Disorders, Parkinson Disease, Sensation Disorders.
- Aged, Chi-Square Distribution, Female, Humans, Male, Middle Aged, Prospective Studies, Statistics, Nonparametric, Surveys and Questionnaires.

Abstract

To assess the frequency and disability caused by nonmotor fluctuations (NMF) in PD.

PubMed: 12177375

Links to Exploration step

pubmed:12177375

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Nonmotor fluctuations in Parkinson's disease: frequent and disabling.</title>
<author><name sortKey="Witjas, Tatiana" sort="Witjas, Tatiana" uniqKey="Witjas T" first="Tatiana" last="Witjas">Tatiana Witjas</name>
<affiliation><nlm:affiliation>Department of Neurology, CHU Timone, 264 rue Saint Pierre, 13385 Marseille cedex 05, France. twitjas@yahoo.fr</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kaphan, E" sort="Kaphan, E" uniqKey="Kaphan E" first="E" last="Kaphan">E. Kaphan</name>
</author>
<author><name sortKey="Azulay, J P" sort="Azulay, J P" uniqKey="Azulay J" first="J P" last="Azulay">J P Azulay</name>
</author>
<author><name sortKey="Blin, O" sort="Blin, O" uniqKey="Blin O" first="O" last="Blin">O. Blin</name>
</author>
<author><name sortKey="Ceccaldi, M" sort="Ceccaldi, M" uniqKey="Ceccaldi M" first="M" last="Ceccaldi">M. Ceccaldi</name>
</author>
<author><name sortKey="Pouget, J" sort="Pouget, J" uniqKey="Pouget J" first="J" last="Pouget">J. Pouget</name>
</author>
<author><name sortKey="Poncet, M" sort="Poncet, M" uniqKey="Poncet M" first="M" last="Poncet">M. Poncet</name>
</author>
<author><name sortKey="Cherif, A Ali" sort="Cherif, A Ali" uniqKey="Cherif A" first="A Ali" last="Chérif">A Ali Chérif</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2002">2002</date>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Nonmotor fluctuations in Parkinson's disease: frequent and disabling.</title>
<author><name sortKey="Witjas, Tatiana" sort="Witjas, Tatiana" uniqKey="Witjas T" first="Tatiana" last="Witjas">Tatiana Witjas</name>
<affiliation><nlm:affiliation>Department of Neurology, CHU Timone, 264 rue Saint Pierre, 13385 Marseille cedex 05, France. twitjas@yahoo.fr</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kaphan, E" sort="Kaphan, E" uniqKey="Kaphan E" first="E" last="Kaphan">E. Kaphan</name>
</author>
<author><name sortKey="Azulay, J P" sort="Azulay, J P" uniqKey="Azulay J" first="J P" last="Azulay">J P Azulay</name>
</author>
<author><name sortKey="Blin, O" sort="Blin, O" uniqKey="Blin O" first="O" last="Blin">O. Blin</name>
</author>
<author><name sortKey="Ceccaldi, M" sort="Ceccaldi, M" uniqKey="Ceccaldi M" first="M" last="Ceccaldi">M. Ceccaldi</name>
</author>
<author><name sortKey="Pouget, J" sort="Pouget, J" uniqKey="Pouget J" first="J" last="Pouget">J. Pouget</name>
</author>
<author><name sortKey="Poncet, M" sort="Poncet, M" uniqKey="Poncet M" first="M" last="Poncet">M. Poncet</name>
</author>
<author><name sortKey="Cherif, A Ali" sort="Cherif, A Ali" uniqKey="Cherif A" first="A Ali" last="Chérif">A Ali Chérif</name>
</author>
</analytic>
<series><title level="j">Neurology</title>
<idno type="ISSN">0028-3878</idno>
<imprint><date when="2002" type="published">2002</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Autonomic Nervous System Diseases (epidemiology)</term>
<term>Autonomic Nervous System Diseases (physiopathology)</term>
<term>Autonomic Nervous System Diseases (psychology)</term>
<term>Chi-Square Distribution</term>
<term>Cognition Disorders (epidemiology)</term>
<term>Cognition Disorders (physiopathology)</term>
<term>Cognition Disorders (psychology)</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (epidemiology)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson Disease (psychology)</term>
<term>Prospective Studies</term>
<term>Sensation Disorders (epidemiology)</term>
<term>Sensation Disorders (physiopathology)</term>
<term>Sensation Disorders (psychology)</term>
<term>Statistics, Nonparametric</term>
<term>Surveys and Questionnaires</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Autonomic Nervous System Diseases</term>
<term>Cognition Disorders</term>
<term>Parkinson Disease</term>
<term>Sensation Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Autonomic Nervous System Diseases</term>
<term>Cognition Disorders</term>
<term>Parkinson Disease</term>
<term>Sensation Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Autonomic Nervous System Diseases</term>
<term>Cognition Disorders</term>
<term>Parkinson Disease</term>
<term>Sensation Disorders</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Chi-Square Distribution</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
<term>Statistics, Nonparametric</term>
<term>Surveys and Questionnaires</term>
</keywords>
</textClass>
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</teiHeader>
<front><div type="abstract" xml:lang="en">To assess the frequency and disability caused by nonmotor fluctuations (NMF) in PD.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">12177375</PMID>
<DateCreated><Year>2002</Year>
<Month>08</Month>
<Day>14</Day>
</DateCreated>
<DateCompleted><Year>2002</Year>
<Month>09</Month>
<Day>03</Day>
</DateCompleted>
<DateRevised><Year>2015</Year>
<Month>11</Month>
<Day>19</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0028-3878</ISSN>
<JournalIssue CitedMedium="Print"><Volume>59</Volume>
<Issue>3</Issue>
<PubDate><Year>2002</Year>
<Month>Aug</Month>
<Day>13</Day>
</PubDate>
</JournalIssue>
<Title>Neurology</Title>
<ISOAbbreviation>Neurology</ISOAbbreviation>
</Journal>
<ArticleTitle>Nonmotor fluctuations in Parkinson's disease: frequent and disabling.</ArticleTitle>
<Pagination><MedlinePgn>408-13</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To assess the frequency and disability caused by nonmotor fluctuations (NMF) in PD.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">A structured questionnaire was administered to 50 patients with PD with motor fluctuations (MF), focused on 54 nonmotor symptoms classified in three subgroups: 26 dysautonomic, 21 cognitive and psychiatric, and seven pain/sensory NMF. The link between each NMF and the motor state was determined. Patients were asked to grade their disability from 0 (no disability) to 4 (maximum discomfort) and to specify which kind of fluctuation subgroup (motor or nonmotor) was the most incapacitating. A statistical analysis was performed to determine the frequency of each NMF and to determine whether the level of disability resulting from NMF could be correlated to the main characteristics of the population.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">All patients had had at least one type of NMF, most of which were associated with the "off" state. Anxiety (66%), drenching sweats (64%), slowness of thinking (58%), fatigue (56%), and akathisia (54%) were the most frequent NMF. Some symptoms such as anxiety or dyspnea correlated with a greater level of disability. The total number of NMF was found to be correlated with the motor disability. Incapacity resulting from the dysautonomic fluctuations was also significantly correlated with levodopa treatment. Surprisingly, 28% of the patients stated that NMF involved a greater degree of disability than MF.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Nonmotor fluctuations are frequent and debilitating in PD.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Witjas</LastName>
<ForeName>Tatiana</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, CHU Timone, 264 rue Saint Pierre, 13385 Marseille cedex 05, France. twitjas@yahoo.fr</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kaphan</LastName>
<ForeName>E</ForeName>
<Initials>E</Initials>
</Author>
<Author ValidYN="Y"><LastName>Azulay</LastName>
<ForeName>J P</ForeName>
<Initials>JP</Initials>
</Author>
<Author ValidYN="Y"><LastName>Blin</LastName>
<ForeName>O</ForeName>
<Initials>O</Initials>
</Author>
<Author ValidYN="Y"><LastName>Ceccaldi</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>Pouget</LastName>
<ForeName>J</ForeName>
<Initials>J</Initials>
</Author>
<Author ValidYN="Y"><LastName>Poncet</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>Chérif</LastName>
<ForeName>A Ali</ForeName>
<Initials>AA</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Neurology</MedlineTA>
<NlmUniqueID>0401060</NlmUniqueID>
<ISSNLinking>0028-3878</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>AIM</CitationSubset>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001342" MajorTopicYN="N">Autonomic Nervous System Diseases</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
<QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016009" MajorTopicYN="N">Chi-Square Distribution</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003072" MajorTopicYN="N">Cognition Disorders</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
<QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName>
<QualifierName UI="Q000523" MajorTopicYN="Y">psychology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012678" MajorTopicYN="N">Sensation Disorders</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
<QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018709" MajorTopicYN="N">Statistics, Nonparametric</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011795" MajorTopicYN="N">Surveys and Questionnaires</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2002</Year>
<Month>8</Month>
<Day>15</Day>
<Hour>10</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2002</Year>
<Month>9</Month>
<Day>11</Day>
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<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">12177375</ArticleId>
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	La maladie de Parkinson en France (serveur d'exploration)
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La maladie de Parkinson en France (serveur d'exploration)

Nonmotor fluctuations in Parkinson's disease: frequent and disabling.

Nonmotor fluctuations in Parkinson's disease: frequent and disabling.

Source :

English descriptors

Abstract

Links to Exploration step

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Pour manipuler ce document sous Unix (Dilib)

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Pour générer des pages wiki