Subthalamic stimulation in Parkinson disease: with or without anesthesia?
Identifieur interne : 001030 ( PubMed/Corpus ); précédent : 001029; suivant : 001031Subthalamic stimulation in Parkinson disease: with or without anesthesia?
Auteurs : David Maltête ; Soledad Navarro ; Marie-Laure Welter ; Sabine Roche ; Anne-Marie Bonnet ; Jean-Luc Houeto ; Valérie Mesnage ; Bernard Pidoux ; Didier Dormont ; Philippe Cornu ; Yves AgidSource :
- Archives of neurology [ 0003-9942 ] ; 2004.
English descriptors
- KwdEn :
- Aged, Antiparkinson Agents (therapeutic use), Case-Control Studies, Disability Evaluation, Dose-Response Relationship, Radiation, Electric Stimulation Therapy (methods), Electrodes, Implanted, Female, Follow-Up Studies, Humans, Levodopa (therapeutic use), Male, Middle Aged, Motor Activity (physiology), Parkinson Disease (therapy), Retrospective Studies, Statistics, Nonparametric, Subthalamic Nucleus (radiation effects), Time Factors, Treatment Outcome.
- MESH :
- chemical , therapeutic use : Antiparkinson Agents, Levodopa.
- methods : Electric Stimulation Therapy.
- physiology : Motor Activity.
- radiation effects : Subthalamic Nucleus.
- therapy : Parkinson Disease.
- Aged, Case-Control Studies, Disability Evaluation, Dose-Response Relationship, Radiation, Electrodes, Implanted, Female, Follow-Up Studies, Humans, Male, Middle Aged, Retrospective Studies, Statistics, Nonparametric, Time Factors, Treatment Outcome.
Abstract
To study the effects of general anesthesia on the postoperative outcome of patients with Parkinson disease (PD) who underwent surgery using bilateral placement of stimulating electrodes within the subthalamic nucleus (STN).
DOI: 10.1001/archneur.61.3.390
PubMed: 15023817
Links to Exploration step
pubmed:15023817Le document en format XML
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<author><name sortKey="Maltete, David" sort="Maltete, David" uniqKey="Maltete D" first="David" last="Maltête">David Maltête</name>
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<author><name sortKey="Navarro, Soledad" sort="Navarro, Soledad" uniqKey="Navarro S" first="Soledad" last="Navarro">Soledad Navarro</name>
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<author><name sortKey="Welter, Marie Laure" sort="Welter, Marie Laure" uniqKey="Welter M" first="Marie-Laure" last="Welter">Marie-Laure Welter</name>
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<author><name sortKey="Roche, Sabine" sort="Roche, Sabine" uniqKey="Roche S" first="Sabine" last="Roche">Sabine Roche</name>
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<author><name sortKey="Bonnet, Anne Marie" sort="Bonnet, Anne Marie" uniqKey="Bonnet A" first="Anne-Marie" last="Bonnet">Anne-Marie Bonnet</name>
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<author><name sortKey="Dormont, Didier" sort="Dormont, Didier" uniqKey="Dormont D" first="Didier" last="Dormont">Didier Dormont</name>
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<author><name sortKey="Cornu, Philippe" sort="Cornu, Philippe" uniqKey="Cornu P" first="Philippe" last="Cornu">Philippe Cornu</name>
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<term>Antiparkinson Agents (therapeutic use)</term>
<term>Case-Control Studies</term>
<term>Disability Evaluation</term>
<term>Dose-Response Relationship, Radiation</term>
<term>Electric Stimulation Therapy (methods)</term>
<term>Electrodes, Implanted</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Levodopa (therapeutic use)</term>
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<term>Middle Aged</term>
<term>Motor Activity (physiology)</term>
<term>Parkinson Disease (therapy)</term>
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<term>Statistics, Nonparametric</term>
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<term>Treatment Outcome</term>
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<keywords scheme="MESH" qualifier="radiation effects" xml:lang="en"><term>Subthalamic Nucleus</term>
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<term>Case-Control Studies</term>
<term>Disability Evaluation</term>
<term>Dose-Response Relationship, Radiation</term>
<term>Electrodes, Implanted</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Retrospective Studies</term>
<term>Statistics, Nonparametric</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
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<front><div type="abstract" xml:lang="en">To study the effects of general anesthesia on the postoperative outcome of patients with Parkinson disease (PD) who underwent surgery using bilateral placement of stimulating electrodes within the subthalamic nucleus (STN).</div>
</front>
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<Day>16</Day>
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<DateCompleted><Year>2004</Year>
<Month>04</Month>
<Day>14</Day>
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<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
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<Issue>3</Issue>
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<Month>Mar</Month>
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<Title>Archives of neurology</Title>
<ISOAbbreviation>Arch. Neurol.</ISOAbbreviation>
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<ArticleTitle>Subthalamic stimulation in Parkinson disease: with or without anesthesia?</ArticleTitle>
<Pagination><MedlinePgn>390-2</MedlinePgn>
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<Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To study the effects of general anesthesia on the postoperative outcome of patients with Parkinson disease (PD) who underwent surgery using bilateral placement of stimulating electrodes within the subthalamic nucleus (STN).</AbstractText>
<AbstractText Label="DESIGN" NlmCategory="METHODS">Retrospective analysis.</AbstractText>
<AbstractText Label="SETTING" NlmCategory="METHODS">Hôpital de la Salpêtrière, Paris, France.</AbstractText>
<AbstractText Label="PATIENTS" NlmCategory="METHODS">Fifteen PD patients who underwent bilateral implantation of electrodes within the STN received general anesthesia because of severe anxiety, poorly tolerated off-period dystonia, or respiratory difficulties. These patients were compared with 15 patients matched for age, disease duration, and parkinsonian motor disability who underwent the same neurosurgical procedure under local anesthesia.</AbstractText>
<AbstractText Label="MAIN OUTCOME MEASURE" NlmCategory="METHODS">Motor disability scores.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">After surgery, the severity of parkinsonian motor disability was markedly improved in both groups of patients. Compared with patients who were under local anesthesia during the operation, the residual parkinsonian motor score under stimulation (with ["on"] or without ["off"] levodopa) and the intensity of stimulation were higher in patients who were under general anesthesia during the operation.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Although the improvement of parkinsonian motor disability is greater in PD patients who receive local anesthesia during surgery, general anesthesia can be performed in patients unable to tolerate prolonged states without levodopa.</AbstractText>
</Abstract>
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