[Apathy and deep brain stimulation in Parkinson's disease].
Identifieur interne : 000846 ( PubMed/Corpus ); précédent : 000845; suivant : 000847[Apathy and deep brain stimulation in Parkinson's disease].
Auteurs : C. Lozachmeur ; D. DrapierSource :
- Revue neurologique [ 0035-3787 ]
English descriptors
- KwdEn :
- MESH :
- adverse effects : Deep Brain Stimulation.
- complications : Parkinson Disease.
- diagnosis : Dementia, Parkinson Disease.
- etiology : Cognition Disorders, Dementia.
- physiology : Apathy.
- psychology : Parkinson Disease.
- therapy : Parkinson Disease.
- Humans.
Abstract
Apathy was defined by Marin as diminished motivation not attributable to diminished level of consciousness, cognitive impairment, or emotional distress. Up to 42% of Parkinson's disease patients could be concerned. It has a pejorative impact on quality of life and could be predictive of cognitive decline. It has been shown that deep brain stimulation in Parkinson's disease may induce apathy. It seems directly related to the stimulation target, i.e. the subthalamic nucleus, since such an effect has not been observed so far in thalamic and pallidal stimulation. It should certainly not make us question the remarkable effectiveness of subthalamic stimulation in Parkinson's disease patients, but encourages us to be very careful about operability criteria. We must, in this sense, improve identification of at risk patients, seeking a thoroughly diminished motivation, loss of interest or blunting affects.
DOI: 10.1016/j.neurol.2012.06.011
PubMed: 22921249
Links to Exploration step
pubmed:22921249Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">[Apathy and deep brain stimulation in Parkinson's disease].</title>
<author><name sortKey="Lozachmeur, C" sort="Lozachmeur, C" uniqKey="Lozachmeur C" first="C" last="Lozachmeur">C. Lozachmeur</name>
<affiliation><nlm:affiliation>Service de psychiatrie et de psychologie médicale, centre hospitalier universitaire Pontchaillou, Rennes, France. clement.lozachmeur@chu-rennes.fr</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Drapier, D" sort="Drapier, D" uniqKey="Drapier D" first="D" last="Drapier">D. Drapier</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="????"><PubDate><MedlineDate>2012 Aug-Sep</MedlineDate>
</PubDate>
</date>
<idno type="RBID">pubmed:22921249</idno>
<idno type="pmid">22921249</idno>
<idno type="doi">10.1016/j.neurol.2012.06.011</idno>
<idno type="wicri:Area/PubMed/Corpus">000846</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000846</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">[Apathy and deep brain stimulation in Parkinson's disease].</title>
<author><name sortKey="Lozachmeur, C" sort="Lozachmeur, C" uniqKey="Lozachmeur C" first="C" last="Lozachmeur">C. Lozachmeur</name>
<affiliation><nlm:affiliation>Service de psychiatrie et de psychologie médicale, centre hospitalier universitaire Pontchaillou, Rennes, France. clement.lozachmeur@chu-rennes.fr</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Drapier, D" sort="Drapier, D" uniqKey="Drapier D" first="D" last="Drapier">D. Drapier</name>
</author>
</analytic>
<series><title level="j">Revue neurologique</title>
<idno type="ISSN">0035-3787</idno>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Apathy (physiology)</term>
<term>Cognition Disorders (etiology)</term>
<term>Deep Brain Stimulation (adverse effects)</term>
<term>Dementia (diagnosis)</term>
<term>Dementia (etiology)</term>
<term>Humans</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (diagnosis)</term>
<term>Parkinson Disease (psychology)</term>
<term>Parkinson Disease (therapy)</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Deep Brain Stimulation</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Dementia</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cognition Disorders</term>
<term>Dementia</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Apathy</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Humans</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Apathy was defined by Marin as diminished motivation not attributable to diminished level of consciousness, cognitive impairment, or emotional distress. Up to 42% of Parkinson's disease patients could be concerned. It has a pejorative impact on quality of life and could be predictive of cognitive decline. It has been shown that deep brain stimulation in Parkinson's disease may induce apathy. It seems directly related to the stimulation target, i.e. the subthalamic nucleus, since such an effect has not been observed so far in thalamic and pallidal stimulation. It should certainly not make us question the remarkable effectiveness of subthalamic stimulation in Parkinson's disease patients, but encourages us to be very careful about operability criteria. We must, in this sense, improve identification of at risk patients, seeking a thoroughly diminished motivation, loss of interest or blunting affects.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">22921249</PMID>
<DateCreated><Year>2012</Year>
<Month>09</Month>
<Day>21</Day>
</DateCreated>
<DateCompleted><Year>2013</Year>
<Month>03</Month>
<Day>04</Day>
</DateCompleted>
<DateRevised><Year>2012</Year>
<Month>09</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">0035-3787</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>168</Volume>
<Issue>8-9</Issue>
<PubDate><MedlineDate>2012 Aug-Sep</MedlineDate>
</PubDate>
</JournalIssue>
<Title>Revue neurologique</Title>
<ISOAbbreviation>Rev. Neurol. (Paris)</ISOAbbreviation>
</Journal>
<ArticleTitle>[Apathy and deep brain stimulation in Parkinson's disease].</ArticleTitle>
<Pagination><MedlinePgn>620-3</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.neurol.2012.06.011</ELocationID>
<ELocationID EIdType="pii" ValidYN="Y">S0035-3787(12)00875-2</ELocationID>
<Abstract><AbstractText>Apathy was defined by Marin as diminished motivation not attributable to diminished level of consciousness, cognitive impairment, or emotional distress. Up to 42% of Parkinson's disease patients could be concerned. It has a pejorative impact on quality of life and could be predictive of cognitive decline. It has been shown that deep brain stimulation in Parkinson's disease may induce apathy. It seems directly related to the stimulation target, i.e. the subthalamic nucleus, since such an effect has not been observed so far in thalamic and pallidal stimulation. It should certainly not make us question the remarkable effectiveness of subthalamic stimulation in Parkinson's disease patients, but encourages us to be very careful about operability criteria. We must, in this sense, improve identification of at risk patients, seeking a thoroughly diminished motivation, loss of interest or blunting affects.</AbstractText>
<CopyrightInformation>Copyright © 2012 Elsevier Masson SAS. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Lozachmeur</LastName>
<ForeName>C</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Service de psychiatrie et de psychologie médicale, centre hospitalier universitaire Pontchaillou, Rennes, France. clement.lozachmeur@chu-rennes.fr</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Drapier</LastName>
<ForeName>D</ForeName>
<Initials>D</Initials>
</Author>
</AuthorList>
<Language>fre</Language>
<PublicationTypeList><PublicationType UI="D004740">English Abstract</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D016454">Review</PublicationType>
</PublicationTypeList>
<VernacularTitle>Apathie et stimulation cérébrale profonde dans la maladie de Parkinson.</VernacularTitle>
<ArticleDate DateType="Electronic"><Year>2012</Year>
<Month>08</Month>
<Day>24</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>France</Country>
<MedlineTA>Rev Neurol (Paris)</MedlineTA>
<NlmUniqueID>2984779R</NlmUniqueID>
<ISSNLinking>0035-3787</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D057565" MajorTopicYN="N">Apathy</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003072" MajorTopicYN="N">Cognition Disorders</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D046690" MajorTopicYN="N">Deep Brain Stimulation</DescriptorName>
<QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003704" MajorTopicYN="N">Dementia</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2012</Year>
<Month>04</Month>
<Day>16</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2012</Year>
<Month>06</Month>
<Day>22</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2012</Year>
<Month>06</Month>
<Day>26</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2012</Year>
<Month>8</Month>
<Day>28</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2012</Year>
<Month>8</Month>
<Day>28</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2013</Year>
<Month>3</Month>
<Day>5</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">22921249</ArticleId>
<ArticleId IdType="pii">S0035-3787(12)00875-2</ArticleId>
<ArticleId IdType="doi">10.1016/j.neurol.2012.06.011</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000846 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000846 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= ParkinsonFranceV1 |flux= PubMed |étape= Corpus |type= RBID |clé= pubmed:22921249 |texte= [Apathy and deep brain stimulation in Parkinson's disease]. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:22921249" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \ | NlmPubMed2Wicri -a ParkinsonFranceV1
![]() | This area was generated with Dilib version V0.6.29. | ![]() |